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Search results 101 to 116 out of 116 for Eda2r

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0.014s

Type

Details

Score

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

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Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

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Publication

18385763 | -

First Author:	Prodi DA
Year:	2008
Journal:	J Invest Dermatol
Title:	EDA2R is associated with androgenetic alopecia.
Volume:	128
Issue:	9
Pages:	2268-70

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Allele

Eda2r<em1Smoc> | MGI:7289440

Name:	ectodysplasin A2 receptor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

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Strain

MGI:6428558 | C57BL/6JSmoc-Eda2R<em1Smoc>/Smoc

Attribute String:

coisogenic, mutant strain, endonuclease-mediated mutation

•

Publication

33594251 | J:334111

First Author:	Song L
Year:	2021
Journal:	Commun Biol
Title:	Macrophage-derived EDA-A2 inhibits intestinal stem cells by targeting miR-494/EDA2R/β-catenin signaling in mice.
Volume:	4
Issue:	1
Pages:	213

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Publication

22889853 | -

First Author:	Wisniewski SA
Year:	2012
Journal:	J Med Genet
Title:	A new mutation resulting in the truncation of the TRAF6-interacting domain of XEDAR: a possible novel cause of hypohidrotic ectodermal dysplasia.
Volume:	49
Issue:	8
Pages:	499-501

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Publication

20501644 | -

First Author:	Tanikawa C
Year:	2010
Journal:	Mol Cancer Res
Title:	Crosstalk of EDA-A2/XEDAR in the p53 signaling pathway.
Volume:	8
Issue:	6
Pages:	855-63

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Publication

19543321 | -

First Author:	Tanikawa C
Year:	2009
Journal:	Oncogene
Title:	XEDAR as a putative colorectal tumor suppressor that mediates p53-regulated anoikis pathway.
Volume:	28
Issue:	34
Pages:	3081-92

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Publication

11039935 | -

First Author:	Yan M
Year:	2000
Journal:	Science
Title:	Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors.
Volume:	290
Issue:	5491
Pages:	523-7

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Protein Domain

IPR034060 | TNFRSF27_N

Type:

Domain

Description:

TNFRSF27 (also known as ectodysplasin-A2 receptor (EDA2R), X-linked ectodermal dysplasia receptor (XEDAR), EDAA2R, EDA-A2R) is a member of the TNFR superfamily that is recognised by ectodysplasin-A2 (EDA-A2), which is generated by alternative splicing of the EDA receptor (EDAR) ligand EDA-A1 []. It is highly expressed during embryonic development and binds to ectodysplasin-A2 (EDA-A2), playing a crucial role in the p53-signaling pathway. EDA2R is a direct p53 target that is frequently down-regulated in colorectal cancer tissues due to its epigenetic alterations or through the p53 gene mutations [, ]. Mutations in the EDA-A2/XEDAR signaling give rise to ectodermal dysplasia, characterized by loss of hair, sweat glands, and teeth []. A non-synonymous SNP on EDA2R, along with genetic variants in human androgen receptor is associated with androgenetic alopecia (AGA) [].This entry represents the N-terminal domain of TNFRSF27/XEDAR. TNF-receptors are modular proteins. The N-terminal extracellular part contains a cysteine-rich region responsible for ligand-binding. This region is composed of small modules of about 40 residues containing 6 conserved cysteines; the number and type of modules can vary in different members of the family [, , ].

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Protein

Q8BX35

Organism:	Mus musculus/domesticus
Length:	297
Fragment?:	false

•

Publication

9538693 | -

First Author:	Naismith JH
Year:	1998
Journal:	Trends Biochem Sci
Title:	Modularity in the TNF-receptor family.
Volume:	23
Issue:	2
Pages:	74-9

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Publication

11796220 | -

First Author:	Bodmer JL
Year:	2002
Journal:	Trends Biochem Sci
Title:	The molecular architecture of the TNF superfamily.
Volume:	27
Issue:	1
Pages:	19-26

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Publication

8387891 | -

First Author:	Banner DW
Year:	1993
Journal:	Cell
Title:	Crystal structure of the soluble human 55 kd TNF receptor-human TNF beta complex: implications for TNF receptor activation.
Volume:	73
Issue:	3
Pages:	431-45

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Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

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