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Search results 101 to 200 out of 241 for Egln3

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:3720212
Assay Type: Immunohistochemistry
Annotation Date: 2007-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:3720213
Age: embryonic day 8.5
Note: Midbody and caudal somites are negative.
Specimen Label: 3A
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3720212
Assay Type: Immunohistochemistry
Annotation Date: 2007-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618413
Pattern: Regionally restricted
Stage: TS13
Assay Id: MGI:3720213
Age: embryonic day 8.5
Note: Midbody and caudal somites are negative.
Specimen Label: 3C
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3720212
Assay Type: Immunohistochemistry
Annotation Date: 2007-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1618415
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:3720213
Age: embryonic day 9.5
Note: Midbody somites are postive, caudal are negative.
Specimen Label: Not shown
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:6285710
Assay Type: RNA in situ
Annotation Date: 2019-04-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:6285713
Age: embryonic day 14.5
Image: S4A top
Specimen Label: S4A top
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6285710
Assay Type: RNA in situ
Annotation Date: 2019-04-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6285713
Age: postnatal adult
Image: S4A bottom
Specimen Label: S4A bottom
Detected: false
Specimen Num: 2
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Publication
26124271 | J:224600
First Author: Chen Y
Year: 2015
Journal: J Biol Chem
Title: PHD3 Stabilizes the Tight Junction Protein Occludin and Protects Intestinal Epithelial Barrier Function.
Volume: 290
Issue: 33
Pages: 20580-9
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Publication
27635760 | J:248932
First Author: German NJ
Year: 2016
Journal: Mol Cell
Title: PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2.
Volume: 63
Issue: 6
Pages: 1006-20
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Publication
30250231 | J:267495
First Author: Yano H
Year: 2018
Journal: Sci Rep
Title: PHD3 regulates glucose metabolism by suppressing stress-induced signalling and optimising gluconeogenesis and insulin signalling in hepatocytes.
Volume: 8
Issue: 1
Pages: 14290
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Publication
24626957 | J:218623
First Author: Swain L
Year: 2014
Journal: J Leukoc Biol
Title: Prolyl-4-hydroxylase domain 3 (PHD3) is a critical terminator for cell survival of macrophages under stress conditions.
Volume: 96
Issue: 3
Pages: 365-75
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Publication
37140003 | J:338024
First Author: Rosiewicz KS
Year: 2023
Journal: Glia
Title: HIF prolyl hydroxylase 2/3 deletion disrupts astrocytic integrity and exacerbates neuroinflammation.
Volume: 71
Issue: 8
Pages: 2024-2044
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Publication
33023907 | J:299411
First Author: Heidenreich S
Year: 2020
Journal: J Biol Chem
Title: The glucose-sensing transcription factor ChREBP is targeted by proline hydroxylation.
Volume: 295
Issue: 50
Pages: 17158-17168
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Publication
25420773 | J:225283
 
First Author: Henze AT
Year: 2014
Journal: Nat Commun
Title: Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR.
Volume: 5
Pages: 5582
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Publication
26995088 | J:234814
First Author: Liu H
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Prolyl hydroxylase 3 overexpression accelerates the progression of atherosclerosis in ApoE-/- mice.
Volume: 473
Issue: 1
Pages: 99-106
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Publication
28939592 | J:269630
First Author: Cai X
Year: 2018
Journal: FASEB J
Title: α-Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway.
Volume: 32
Issue: 1
Pages: 488-499
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Publication
25385837 | J:229209
First Author: Macías D
Year: 2014
Journal: EMBO Mol Med
Title: Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia.
Volume: 6
Issue: 12
Pages: 1577-92
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Publication
20733101 | J:179490
First Author: Moslehi J
Year: 2010
Journal: Circulation
Title: Loss of hypoxia-inducible factor prolyl hydroxylase activity in cardiomyocytes phenocopies ischemic cardiomyopathy.
Volume: 122
Issue: 10
Pages: 1004-16
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Publication
26774962 | J:232857
First Author: Quaegebeur A
Year: 2016
Journal: Cell Metab
Title: Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism.
Volume: 23
Issue: 2
Pages: 280-91
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Publication
32814068 | J:301250
 
First Author: Smaila BD
Year: 2020
Journal: Exp Neurol
Title: Systemic hypoxia mimicry enhances axonal regeneration and functional recovery following peripheral nerve injury.
Volume: 334
Pages: 113436
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Publication
24440788 | J:206444
First Author: Takeda K
Year: 2014
Journal: Am J Pathol
Title: Improved vascular survival and growth in the mouse model of hindlimb ischemia by a remote signaling mechanism.
Volume: 184
Issue: 3
Pages: 686-96
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Publication
24508125 | J:208042
First Author: Duan LJ
Year: 2014
Journal: Am J Pathol
Title: Hematological, hepatic, and retinal phenotypes in mice deficient for prolyl hydroxylase domain proteins in the liver.
Volume: 184
Issue: 4
Pages: 1240-50
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Publication
27981571 | J:241898
First Author: Van Welden S
Year: 2017
Journal: J Pathol
Title: Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis.
Volume: 241
Issue: 4
Pages: 547-558
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Publication
17646578 | J:133568
First Author: Takeda K
Year: 2007
Journal: Circulation
Title: Essential role for prolyl hydroxylase domain protein 2 in oxygen homeostasis of the adult vascular system.
Volume: 116
Issue: 7
Pages: 774-81
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Publication
18056838 | J:132720
First Author: Takeda K
Year: 2008
Journal: Blood
Title: Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins.
Volume: 111
Issue: 6
Pages: 3229-35
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Publication
26075818 | J:225429
First Author: Xie L
Year: 2015
Journal: J Clin Invest
Title: PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban.
Volume: 125
Issue: 7
Pages: 2759-71
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Publication
33464382 | J:306672
First Author: Watts D
Year: 2021
Journal: Cell Mol Life Sci
Title: HIF1α is a direct regulator of steroidogenesis in the adrenal gland.
Volume: 78
Issue: 7
Pages: 3577-3590
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Publication
33819286 | J:304962
First Author: Wei GZ
Year: 2021
Journal: PLoS One
Title: Hypoxia-inducible factor prolyl hydroxylase domain (PHD) inhibition after contusive spinal cord injury does not improve locomotor recovery.
Volume: 16
Issue: 4
Pages: e0249591
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Publication
26818499 | J:229447
First Author: Rajagopalan S
Year: 2016
Journal: J Neurosci
Title: Regulation of ATP13A2 via PHD2-HIF1α Signaling Is Critical for Cellular Iron Homeostasis: Implications for Parkinson's Disease.
Volume: 36
Issue: 4
Pages: 1086-95
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Publication
22786772 | J:189753
First Author: Kiss J
Year: 2012
Journal: J Immunol
Title: Loss of the oxygen sensor PHD3 enhances the innate immune response to abdominal sepsis.
Volume: 189
Issue: 4
Pages: 1955-65
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Publication
22615432 | J:200057
First Author: Chen RL
Year: 2012
Journal: J Physiol
Title: Roles of individual prolyl-4-hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice.
Volume: 590
Issue: 16
Pages: 4079-91
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Publication
30248340 | J:270770
First Author: Strowitzki MJ
Year: 2018
Journal: Am J Pathol
Title: Loss of Prolyl-Hydroxylase 1 Protects against Biliary Fibrosis via Attenuated Activation of Hepatic Stellate Cells.
Volume: 188
Issue: 12
Pages: 2826-2838
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Publication
27614241 | J:237383
First Author: Zhu K
Year: 2016
Journal: Gene
Title: Prolyl hydroxylase domain proteins regulate bone mass through their expression in osteoblasts.
Volume: 594
Issue: 1
Pages: 125-130
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Publication
27561929 | J:241612
 
First Author: Chowdhury R
Year: 2016
Journal: Nat Commun
Title: Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases.
Volume: 7
Pages: 12673
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Publication
31029587 | J:274809
 
First Author: Leinonen H
Year: 2019
Journal: Neuropharmacology
Title: Null mutation in P4h-tm leads to decreased fear and anxiety and increased social behavior in mice.
Volume: 153
Pages: 63-72
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Publication
28716863 | J:247886
First Author: Tavernier SJ
Year: 2017
Journal: J Leukoc Biol
Title: Opposing regulation and roles for PHD3 in lung dendritic cells and alveolar macrophages.
Volume: 102
Issue: 4
Pages: 1115-1126
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Publication
36509284 | J:332130
 
First Author: Kennel KB
Year: 2022
Journal: JCI Insight
Title: The HIF-prolyl hydroxylases have distinct and nonredundant roles in colitis-associated cancer.
Volume: 7
Issue: 22
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Publication
23690557 | J:212783
First Author: Bishop T
Year: 2013
Journal: J Physiol
Title: Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.
Volume: 591
Issue: 14
Pages: 3565-77
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Publication
28418093 | J:243598
First Author: Hulley PA
Year: 2017
Journal: J Pathol
Title: Hypoxia-inducible factor 1-alpha does not regulate osteoclastogenesis but enhances bone resorption activity via prolyl-4-hydroxylase 2.
Volume: 242
Issue: 3
Pages: 322-333
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Publication
20600011 | J:309903
First Author: Tambuwala MM
Year: 2010
Journal: Gastroenterology
Title: Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function.
Volume: 139
Issue: 6
Pages: 2093-101
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Publication
24037093 | J:202021
First Author: Taniguchi CM
Year: 2013
Journal: Nat Med
Title: Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes.
Volume: 19
Issue: 10
Pages: 1325-30
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Publication
33298456 | J:313923
 
First Author: Byts N
Year: 2021
Journal: eNeuro
Title: Transmembrane Prolyl 4-Hydroxylase is a Novel Regulator of Calcium Signaling in Astrocytes.
Volume: 8
Issue: 1
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Publication
22955912 | J:213191
First Author: Laitala A
Year: 2012
Journal: Blood
Title: Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis.
Volume: 120
Issue: 16
Pages: 3336-44
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Publication
22262480 | J:183424
First Author: Kapitsinou PP
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Preischemic targeting of HIF prolyl hydroxylation inhibits fibrosis associated with acute kidney injury.
Volume: 302
Issue: 9
Pages: F1172-9
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Publication
25446011 | J:319086
 
First Author: Rishi MT
Year: 2015
Journal: Microvasc Res
Title: Deletion of prolyl hydroxylase domain proteins (PHD1, PHD3) stabilizes hypoxia inducible factor-1 alpha, promotes neovascularization, and improves perfusion in a murine model of hind-limb ischemia.
Volume: 97
Pages: 181-8
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Publication
28538180 | J:254708
First Author: Yoshinaga M
Year: 2017
Journal: Cell Rep
Title: Regnase-1 Maintains Iron Homeostasis via the Degradation of Transferrin Receptor 1 and Prolyl-Hydroxylase-Domain-Containing Protein 3 mRNAs.
Volume: 19
Issue: 8
Pages: 1614-1630
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Publication
27795296 | J:242994
 
First Author: Guentsch A
Year: 2017
Journal: Mol Cell Biol
Title: PHD2 Is a Regulator for Glycolytic Reprogramming in Macrophages.
Volume: 37
Issue: 1
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Publication
34610308 | J:326966
First Author: Angelini A
Year: 2021
Journal: Cell Rep
Title: PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes.
Volume: 37
Issue: 1
Pages: 109767
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Publication
23264599 | J:194598
First Author: Franke K
Year: 2013
Journal: Blood
Title: HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis.
Volume: 121
Issue: 8
Pages: 1436-45
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Publication
22611156 | J:189129
First Author: Querbes W
Year: 2012
Journal: Blood
Title: Treatment of erythropoietin deficiency in mice with systemically administered siRNA.
Volume: 120
Issue: 9
Pages: 1916-22
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Publication
34718519 | J:323854
 
First Author: Hoang M
Year: 2022
Journal: Endocrinology
Title: Isoform-specific Roles of Prolyl Hydroxylases in the Regulation of Pancreatic β-Cell Function.
Volume: 163
Issue: 1
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Publication
24030251 | J:211224
First Author: Bondeva T
Year: 2013
Journal: Mol Endocrinol
Title: Advanced glycated end-products affect HIF-transcriptional activity in renal cells.
Volume: 27
Issue: 11
Pages: 1918-33
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Publication
15210114 | J:91356
First Author: Nakayama K
Year: 2004
Journal: Cell
Title: Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia.
Volume: 117
Issue: 7
Pages: 941-52
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Publication
24145445 | J:202913
First Author: Scholz CC
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.
Volume: 110
Issue: 46
Pages: 18490-5
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Publication
18176562 | J:132630
First Author: Aragonés J
Year: 2008
Journal: Nat Genet
Title: Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism.
Volume: 40
Issue: 2
Pages: 170-80
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Publication
22014577 | J:177485
First Author: Adam J
Year: 2011
Journal: Cancer Cell
Title: Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling.
Volume: 20
Issue: 4
Pages: 524-37
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Publication
37400498 | J:341078
First Author: Zhang T
Year: 2023
Journal: Nat Cell Biol
Title: Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.
Volume: 25
Issue: 7
Pages: 950-962
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Publication
22464323 | J:186085
First Author: Rankin EB
Year: 2012
Journal: Cell
Title: The HIF signaling pathway in osteoblasts directly modulates erythropoiesis through the production of EPO.
Volume: 149
Issue: 1
Pages: 63-74
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Publication
20651146 | J:162614
First Author: Minamishima YA
Year: 2010
Journal: Science
Title: Reactivation of hepatic EPO synthesis in mice after PHD loss.
Volume: 329
Issue: 5990
Pages: 407
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Publication
32663458 | J:296608
First Author: Yoon H
Year: 2020
Journal: Cell Metab
Title: PHD3 Loss Promotes Exercise Capacity and Fat Oxidation in Skeletal Muscle.
Volume: 32
Issue: 2
Pages: 215-228.e7
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Publication
26054543 | J:293573
First Author: Souma T
Year: 2016
Journal: J Am Soc Nephrol
Title: Erythropoietin Synthesis in Renal Myofibroblasts Is Restored by Activation of Hypoxia Signaling.
Volume: 27
Issue: 2
Pages: 428-38
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Publication
38518771 | J:351589
First Author: Nolan ND
Year: 2024
Journal: Cell Rep Med
Title: CRISPR editing of anti-anemia drug target rescues independent preclinical models of retinitis pigmentosa.
Volume: 5
Issue: 4
Pages: 101459
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Publication
23649506 | J:244618
First Author: Zhu K
Year: 2013
Journal: J Bone Miner Res
Title: ATF4 promotes bone angiogenesis by increasing VEGF expression and release in the bone environment.
Volume: 28
Issue: 9
Pages: 1870-1884
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Publication
27565342 | J:234541
First Author: Clever D
Year: 2016
Journal: Cell
Title: Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche.
Volume: 166
Issue: 5
Pages: 1117-1131.e14
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Publication
25846796 | J:221580
First Author: Wu C
Year: 2015
Journal: Genes Dev
Title: Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin.
Volume: 29
Issue: 8
Pages: 817-31
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Publication
27088801 | J:234932
First Author: Kobayashi H
Year: 2016
Journal: J Clin Invest
Title: Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin.
Volume: 126
Issue: 5
Pages: 1926-38
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Publication
18347341 | J:133348
First Author: Ginouvès A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: PHDs overactivation during chronic hypoxia "desensitizes" HIFalpha and protects cells from necrosis.
Volume: 105
Issue: 12
Pages: 4745-50
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Publication
18040029 | J:142981
First Author: Chang EI
Year: 2007
Journal: Circulation
Title: Age decreases endothelial progenitor cell recruitment through decreases in hypoxia-inducible factor 1alpha stabilization during ischemia.
Volume: 116
Issue: 24
Pages: 2818-29
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Publication
24828078 | J:215343
First Author: Taniguchi CM
Year: 2014
Journal: Sci Transl Med
Title: PHD inhibition mitigates and protects against radiation-induced gastrointestinal toxicity via HIF2.
Volume: 6
Issue: 236
Pages: 236ra64
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Publication
27683416 | J:237355
First Author: Urrutia AA
Year: 2016
Journal: Blood
Title: Prolyl-4-hydroxylase 2 and 3 coregulate murine erythropoietin in brain pericytes.
Volume: 128
Issue: 21
Pages: 2550-2560
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Publication
20926767 | J:166934
First Author: Trollmann R
Year: 2010
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Late-gestational systemic hypoxia leads to a similar early gene response in mouse placenta and developing brain.
Volume: 299
Issue: 6
Pages: R1489-99
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Publication
37509073 | J:338819
 
First Author: Wulf S
Year: 2023
Journal: Biomolecules
Title: Targeted Disruption of the MORG1 Gene in Mice Causes Embryonic Resorption in Early Phase of Development.
Volume: 13
Issue: 7
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Publication
27325674 | J:236168
First Author: Arsenault PR
Year: 2016
Journal: Mol Cell Biol
Title: The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α.
Volume: 36
Issue: 18
Pages: 2328-43
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Publication
35242281 | J:321522
 
First Author: Kirschner KM
Year: 2022
Journal: Oxid Med Cell Longev
Title: Adaptation of the Oxygen Sensing System during Lung Development.
Volume: 2022
Pages: 9714669
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Publication
22342504 | J:317897
First Author: Gruzdev A
Year: 2012
Journal: Prostaglandins Other Lipid Mediat
Title: PGE2 through the EP4 receptor controls smooth muscle gene expression patterns in the ductus arteriosus critical for remodeling at birth.
Volume: 97
Issue: 3-4
Pages: 109-19
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Publication
26972007 | J:234716
First Author: Segura I
Year: 2016
Journal: Cell Rep
Title: The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A.
Volume: 14
Issue: 11
Pages: 2653-67
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Publication
24748541 | J:225226
First Author: Dykes IM
Year: 2014
Journal: Circ Res
Title: HIC2 is a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region.
Volume: 115
Issue: 1
Pages: 23-31
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Publication
16966370 | J:114669
First Author: Takeda K
Year: 2006
Journal: Mol Cell Biol
Title: Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2.
Volume: 26
Issue: 22
Pages: 8336-46
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Publication
21270129 | J:170943
First Author: Hölscher M
Year: 2011
Journal: J Biol Chem
Title: Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury.
Volume: 286
Issue: 13
Pages: 11185-94
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Publication
26856890 | J:231532
First Author: Lange C
Year: 2016
Journal: EMBO J
Title: Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis.
Volume: 35
Issue: 9
Pages: 924-41
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Publication
33665549 | J:306925
First Author: Menendez-Montes I
Year: 2021
Journal: iScience
Title: Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice.
Volume: 24
Issue: 2
Pages: 102124
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Publication
28262664 | J:245009
 
First Author: Himmels P
Year: 2017
Journal: Nat Commun
Title: Motor neurons control blood vessel patterning in the developing spinal cord.
Volume: 8
Pages: 14583
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Publication
28847650 | J:320427
First Author: Kobayashi H
Year: 2017
Journal: Kidney Int
Title: Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development.
Volume: 92
Issue: 6
Pages: 1370-1383
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