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Search results 101 to 144 out of 144 for Eif1

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Hits by Pathway

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Hits by Strain

Type Details Score
Strain
MGI:5004318 | STOCK Tg(Eif1-EGFP)LC125Gsat/Mmucd
Attribute String: mutant stock, transgenic
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GO Term
GO:0033290 | eukaryotic 48S preinitiation complex
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Protein
A0A0U1RPR0
Organism: Mus musculus/domesticus
Length: 66  
Fragment?: false
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Protein Domain
IPR008905 | EIF3C_N_dom
Type: Domain
Description: The largest of the mammalian translation initiation factors, eIF3, consists of at least eight subunits ranging in mass from 35 to 170kDa. eIF3 binds to the 40 S ribosome in an early step of translation initiation and promotes the binding of methionyl-tRNAi and mRNA []. The N-terminal domain of eukaryotic translation initiation factor 3 subunit C mediates eIF3 binding to eIF1 and eIF5 [].
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Protein
Q8BVX3
Organism: Mus musculus/domesticus
Length: 268  
Fragment?: true
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Protein
Q3TL08
Organism: Mus musculus/domesticus
Length: 241  
Fragment?: true
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Protein
Q9CSD3
Organism: Mus musculus/domesticus
Length: 241  
Fragment?: true
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Protein
Q9CV26
Organism: Mus musculus/domesticus
Length: 121  
Fragment?: true
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Protein
M0QWV3
Organism: Mus musculus/domesticus
Length: 249  
Fragment?: true
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Publication
10376878 | -
First Author: Cui Y
Year: 1999
Journal: RNA
Title: Mutations in the MOF2/SUI1 gene affect both translation and nonsense-mediated mRNA decay.
Volume: 5
Issue: 6
Pages: 794-804
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Publication
9488467 | -
First Author: Cui Y
Year: 1998
Journal: Mol Cell Biol
Title: The Mof2/Sui1 protein is a general monitor of translational accuracy.
Volume: 18
Issue: 3
Pages: 1506-16
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Publication
22718758 | -
First Author: Karásková M
Year: 2012
Journal: J Biol Chem
Title: Functional characterization of the role of the N-terminal domain of the c/Nip1 subunit of eukaryotic initiation factor 3 (eIF3) in AUG recognition.
Volume: 287
Issue: 34
Pages: 28420-34
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Protein Domain
IPR005874 | SUI1_euk
Type: Family
Description: eIF1/SUI1 (eukaryotic initiation factor 1) plays an important role in accurate initiator codon recognition during translation initiation. eIF1 interacts with 18S rRNA in the 40S ribosomal subunitduring eukaryotic translation initiation. Point mutations in the yeast eIF1 implicate the protein in maintaining accurate start-site selection but its mechanism of action is unknown [].Cells have evolved elaborate mechanisms to rid themselves of aberrant proteins and transcripts. The nonsense-mediated mRNA decay pathway (NMD) is an example of a pathway that eliminates aberrant mRNAs. In addition to its role in recognition of the AUG codon during translation initiation and maintenance of the appropriate reading frame during translation elongation by directing the ribosome to the proper start site of translation by functioning in concert with eIF-2 and the initiator tRNA-Met, the SUI1 protein plays a role in the NMD pathway [].
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Publication
22123745 | -
First Author: Kouba T
Year: 2012
Journal: Nucleic Acids Res
Title: The eIF3c/NIP1 PCI domain interacts with RNA and RACK1/ASC1 and promotes assembly of translation preinitiation complexes.
Volume: 40
Issue: 6
Pages: 2683-99
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Protein Domain
IPR027516 | EIF3C
Type: Family
Description: Eukaryotic translation initiation factor 3 subunit C (EIF3C) is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. EIF3C appears to be important for eIF3 activity []. Its N-terminal domain mediates eIF3 binding to eIF1 and eIF5 [], and its C-terminal PCI domain forms an important intermolecular bridge between eIF3 and the 40S ribosome [].
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Publication
10347211 | J:55433
First Author: Sheikh MS
Year: 1999
Journal: J Biol Chem
Title: Cloning and characterization of a human genotoxic and endoplasmic reticulum stress-inducible cDNA that encodes translation initiation factor 1(eIF1(A121/SUI1)).
Volume: 274
Issue: 23
Pages: 16487-93
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Protein
Q9CXU9
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: false
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Protein
A0A1L1SSA3
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: true
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Protein
J3QN87
Organism: Mus musculus/domesticus
Length: 90  
Fragment?: true
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Protein
Q3UBT8
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: false
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Protein
Q4V9T8
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: false
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Protein Coding Gene
MGI:95298 | Eif1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1925905 | Eif3j1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3704486 | Eif3j2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1926966 | Eif3c
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1913485 | Eif1ax
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q8R1B4
Organism: Mus musculus/domesticus
Length: 911  
Fragment?: false
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Protein
Q66JU1
Organism: Mus musculus/domesticus
Length: 402  
Fragment?: true
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Protein
P97398
Organism: Mus musculus/domesticus
Length: 323  
Fragment?: false
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Protein Coding Gene
MGI:1915385 | Eif3h
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1351744 | Eif3m
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1860763 | Eif3i
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1921080 | Eif3k
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1858258 | Eif3g
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:99257 | Eif3e
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1933181 | Eif3d
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2386251 | Eif3l
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:106478 | Eif3b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1913335 | Eif3f
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95301 | Eif3a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17581632 | J:148056
First Author: Masutani M
Year: 2007
Journal: EMBO J
Title: Reconstitution reveals the functional core of mammalian eIF3.
Volume: 26
Issue: 14
Pages: 3373-83
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Publication
8995409 | -
First Author: Asano K
Year: 1997
Journal: J Biol Chem
Title: Conservation and diversity of eukaryotic translation initiation factor eIF3.
Volume: 272
Issue: 2
Pages: 1101-9
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Protein Coding Gene
MGI:95299 | Eif2s1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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