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Search results 101 to 170 out of 170 for Elovl7

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Type Details Score
Publication
27889898 | J:314321
First Author: Moruzzo D
Year: 2017
Journal: Mol Neurobiol
Title: The Transcription Factors EBF1 and EBF2 Are Positive Regulators of Myelination in Schwann Cells.
Volume: 54
Issue: 10
Pages: 8117-8127
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Publication
26928066 | J:234565
First Author: He D
Year: 2016
Journal: Nat Neurosci
Title: Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination.
Volume: 19
Issue: 5
Pages: 678-89
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Publication
37115925 | J:335426
First Author: Butera A
Year: 2023
Journal: Sci Adv
Title: ZFP750 affects the cutaneous barrier through regulating lipid metabolism.
Volume: 9
Issue: 17
Pages: eadg5423
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Publication
25269881 | J:216600
First Author: Lau CG
Year: 2014
Journal: Mol Reprod Dev
Title: Morphology-based mammalian stem cell tests reveal potential developmental toxicity of donepezil.
Volume: 81
Issue: 11
Pages: 994-1008
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Publication
27760309 | J:240758
First Author: Duteil D
Year: 2016
Journal: Cell Rep
Title: Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.
Volume: 17
Issue: 4
Pages: 1008-1021
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Publication
- | J:342612
       
First Author: UniProt curators
Year: 2014
Title: Electronic Gene Ontology annotations created by transferring manual GO annotations between related proteins based on shared sequence features
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Publication
- | J:147112
     
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
20035504 | J:162057
First Author: Shin D
Year: 2009
Journal: Ann Neurol
Title: Dicer ablation in oligodendrocytes provokes neuronal impairment in mice.
Volume: 66
Issue: 6
Pages: 843-57
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HT Experiment
GSE220813 | ZFP750 regulates skin lipid metabolism and cutaneous barrier
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Protein
A0A0G2JFD6
Organism: Mus musculus/domesticus
Length: 74  
Fragment?: false
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Publication
7768822 | -
First Author: el-Sherbeini M
Year: 1995
Journal: J Bacteriol
Title: Cloning and characterization of GNS1: a Saccharomyces cerevisiae gene involved in synthesis of 1,3-beta-glucan in vitro.
Volume: 177
Issue: 11
Pages: 3227-34
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Publication
8027068 | -
First Author: García-Arranz M
Year: 1994
Journal: J Biol Chem
Title: Transcriptional control of yeast plasma membrane H(+)-ATPase by glucose. Cloning and characterization of a new gene involved in this regulation.
Volume: 269
Issue: 27
Pages: 18076-82
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Publication
29458843 | -
 
First Author: Wang Q
Year: 2018
Journal: Microbiol Res
Title: A critical role for very long-chain fatty acid elongases in oleic acid-mediated Saccharomyces cerevisiae cytotoxicity.
Volume: 207
Pages: 1-7
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Publication
21959040 | -
First Author: Naganuma T
Year: 2011
Journal: FEBS Lett
Title: Biochemical characterization of the very long-chain fatty acid elongase ELOVL7.
Volume: 585
Issue: 20
Pages: 3337-41
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Publication
30487246 | -
First Author: Mueller N
Year: 2019
Journal: J Med Genet
Title: De novo mutation in ELOVL1 causes ichthyosis, acanthosis nigricans, hypomyelination, spastic paraplegia, high frequency deafness and optic atrophy.
Volume: 56
Issue: 3
Pages: 164-175
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Protein Domain
IPR002076 | ELO_fam
Type: Family
Description: The ELO family consist of eukaryotic integral membrane proteins involved in fatty acid elongation. This family consist of:Mammalian proteins ELOVL1 to ELOVL7 [, ]. These proteins catalyse the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle, each of them has a specific substrate specificity and physiological functions.Yeast ELO1, ELO2 and ELO3 [, ]. They are components of a microsomal membrane-bound long-chain fatty acid elongation system.Caenorhabditis elegans hypothetical protein C40H1.4.Caenorhabditis elegans hypothetical protein D2024.3.This group of eukaryotic integral membrane proteinsare evolutionary related and have from 290 to 435 amino acid residues. Structurally, they seem to be formed of three sections: a N-terminal region with two transmembrane domains, a central hydrophilic loop and a C-terminal region that contains from one to three transmembrane domains. Members of this family are involved in long chain fatty acid elongation systems that produce the 26-carbon precursors for ceramide and sphingolipid synthesis []. Yeast ELO3 () affects plasma membrane H+-ATPase activity, and may act on a glucose-signalling pathway that controls the expression of several genes that are transcriptionally regulated by glucose such as PMA1 []. It plays an important role in lipotoxic cell death induced by oleic acid through maintaining a balanced fatty acid composition in the plasma membrane []. Mammalian ELOVLs are also associated with known pathologies. ELOVL1 catalyses elongation of saturated and monounsaturated C22-C26-VLCFAs, and dominant mutations cause ichthyosis, hypomyelination of the central white matter that leads to spastic paraplegia and central nystagmus and optic atrophy [], dominant ELOVL4 mutations cause a juvenile macular dystrophy (Stargardt disease-3) and Elovl4 knockout mice die soon after birth due to a deficiency in skin barrier formation. Studies in Elovl6-null mice have revealed that ELOVL6 is involved in an obesity-induced insulin resistance and ELOVL7 is involved in prostate cancer growth [].
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Publication
10791983 | J:61900
First Author: Tvrdik P
Year: 2000
Journal: J Cell Biol
Title: Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids.
Volume: 149
Issue: 3
Pages: 707-18
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Protein
Q8BHI7
Organism: Mus musculus/domesticus
Length: 299  
Fragment?: false
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Protein
A0A0G2JGX5
Organism: Mus musculus/domesticus
Length: 36  
Fragment?: true
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Protein
Q3TS46
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: true
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Protein
D3Z0Z6
Organism: Mus musculus/domesticus
Length: 71  
Fragment?: true
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Protein
X2EXE4
Organism: Mus musculus/domesticus
Length: 299  
Fragment?: true
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Protein
V9GXI2
Organism: Mus musculus/domesticus
Length: 181  
Fragment?: true
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Protein
Q9WU14
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
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Protein
D3Z136
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
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Protein
Q4V9V3
Organism: Mus musculus/domesticus
Length: 202  
Fragment?: false
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Publication
9211877 | -
First Author: Oh CS
Year: 1997
Journal: J Biol Chem
Title: ELO2 and ELO3, homologues of the Saccharomyces cerevisiae ELO1 gene, function in fatty acid elongation and are required for sphingolipid formation.
Volume: 272
Issue: 28
Pages: 17376-84
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Protein
Q9JLJ5
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: false
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Protein
Q9JLJ4
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: false
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Protein
Q920L5
Organism: Mus musculus/domesticus
Length: 267  
Fragment?: false
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Protein
Q9EQC4
Organism: Mus musculus/domesticus
Length: 312  
Fragment?: false
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Protein
O35949
Organism: Mus musculus/domesticus
Length: 271  
Fragment?: false
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Protein
X2EXH0
Organism: Mus musculus/domesticus
Length: 273  
Fragment?: true
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Protein
A0A498WFQ4
Organism: Mus musculus/domesticus
Length: 248  
Fragment?: false
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Protein
A0A0R4J1P7
Organism: Mus musculus/domesticus
Length: 275  
Fragment?: false
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Protein
A0A0G2JFE8
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: true
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Protein
Q548M4
Organism: Mus musculus/domesticus
Length: 279  
Fragment?: false
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Protein
Q543J1
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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