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Search results 101 to 200 out of 206 for Emd

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Type Details Score
Publication
21525034 | J:182943
First Author: Dedeic Z
Year: 2011
Journal: J Cell Sci
Title: Emerin inhibits Lmo7 binding to the Pax3 and MyoD promoters and expression of myoblast proliferation genes.
Volume: 124
Issue: Pt 10
Pages: 1691-702
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Publication
28088180 | J:313343
First Author: Smith ER
Year: 2017
Journal: BMC Cell Biol
Title: Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression.
Volume: 18
Issue: 1
Pages: 8
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Publication
31430335 | J:278718
First Author: Wada E
Year: 2019
Journal: PLoS One
Title: Deficiency of emerin contributes differently to the pathogenesis of skeletal and cardiac muscles in LmnaH222P/H222P mutant mice.
Volume: 14
Issue: 8
Pages: e0221512
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Publication
32535204 | J:305046
 
First Author: Hu Q
Year: 2020
Journal: Int J Biol Macromol
Title: Neural-specific distribution of transmembrane protein TMEM240 and formation of TMEM240-Body.
Volume: 161
Pages: 692-703
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Publication
12670476 | J:83147
First Author: Lattanzi G
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Association of emerin with nuclear and cytoplasmic actin is regulated in differentiating myoblasts.
Volume: 303
Issue: 3
Pages: 764-70
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Publication
28188262 | J:241879
First Author: Collins CM
Year: 2017
Journal: Dis Model Mech
Title: MAPK signaling pathways and HDAC3 activity are disrupted during differentiation of emerin-null myogenic progenitor cells.
Volume: 10
Issue: 4
Pages: 385-397
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Publication
18230648 | J:138280
First Author: Bengtsson L
Year: 2008
Journal: J Cell Sci
Title: LUMA interacts with emerin and influences its distribution at the inner nuclear membrane.
Volume: 121
Issue: Pt 4
Pages: 536-48
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Publication
25274778 | J:218095
First Author: Stubenvoll A
Year: 2015
Journal: Hum Mol Genet
Title: Attenuation of Wnt/β-catenin activity reverses enhanced generation of cardiomyocytes and cardiac defects caused by the loss of emerin.
Volume: 24
Issue: 3
Pages: 802-13
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Publication
19933576 | J:159127
First Author: Haque F
Year: 2010
Journal: J Biol Chem
Title: Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.
Volume: 285
Issue: 5
Pages: 3487-98
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Publication
23644458 | J:198746
First Author: Ho CY
Year: 2013
Journal: Nature
Title: Lamin A/C and emerin regulate MKL1-SRF activity by modulating actin dynamics.
Volume: 497
Issue: 7450
Pages: 507-11
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Publication
35150612 | J:321903
First Author: Tang Y
Year: 2022
Journal: Dev Cell
Title: Matrix remodeling controls a nuclear lamin A/C-emerin network that directs Wnt-regulated stem cell fate.
Volume: 57
Issue: 4
Pages: 480-495.e6
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Publication
19022376 | J:143904
First Author: Muchir A
Year: 2009
Journal: Biochim Biophys Acta
Title: Reduced expression of A-type lamins and emerin activates extracellular signal-regulated kinase in cultured cells.
Volume: 1792
Issue: 1
Pages: 75-81
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Publication
19126678 | J:146194
First Author: Tilgner K
Year: 2009
Journal: J Cell Sci
Title: Dynamic complexes of A-type lamins and emerin influence adipogenic capacity of the cell via nucleocytoplasmic distribution of beta-catenin.
Volume: 122
Issue: Pt 3
Pages: 401-13
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Publication
19720741 | J:153986
First Author: Huber MD
Year: 2009
Journal: Mol Cell Biol
Title: Overlapping functions of nuclear envelope proteins NET25 (Lem2) and emerin in regulation of extracellular signal-regulated kinase signaling in myoblast differentiation.
Volume: 29
Issue: 21
Pages: 5718-28
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Publication
22349700 | J:197280
First Author: Borrego-Pinto J
Year: 2012
Journal: J Cell Sci
Title: Samp1 is a component of TAN lines and is required for nuclear movement.
Volume: 125
Issue: Pt 5
Pages: 1099-105
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Publication
23374351 | J:193454
First Author: Solovei I
Year: 2013
Journal: Cell
Title: LBR and lamin A/C sequentially tether peripheral heterochromatin and inversely regulate differentiation.
Volume: 152
Issue: 3
Pages: 584-98
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Publication
31128203 | J:285646
First Author: Sola-Carvajal A
Year: 2019
Journal: J Invest Dermatol
Title: Accumulation of Progerin Affects the Symmetry of Cell Division and Is Associated with Impaired Wnt Signaling and the Mislocalization of Nuclear Envelope Proteins.
Volume: 139
Issue: 11
Pages: 2272-2280.e12
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Publication
38569934 | J:347982
First Author: Li C
Year: 2024
Journal: J Biol Chem
Title: Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere.
Volume: 300
Issue: 5
Pages: 107254
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Publication
11591818 | J:74817
First Author: Nili E
Year: 2001
Journal: J Cell Sci
Title: Nuclear membrane protein LAP2beta mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less).
Volume: 114
Issue: Pt 18
Pages: 3297-307
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Publication
17164264 | J:117855
First Author: Heydemann A
Year: 2007
Journal: Hum Mol Genet
Title: Nuclear sequestration of delta-sarcoglycan disrupts the nuclear localization of lamin A/C and emerin in cardiomyocytes.
Volume: 16
Issue: 4
Pages: 355-63
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Publication
7490070 | J:26634
First Author: Rivella S
Year: 1995
Journal: Genomics
Title: A comparative transcriptional map of a region of 250 kb on the human and mouse X chromosome between the G6PD and the FLN1 genes.
Volume: 28
Issue: 3
Pages: 377-82
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Publication
28533284 | J:246890
First Author: Stroud MJ
Year: 2017
Journal: J Cell Biol
Title: Nesprin 1α2 is essential for mouse postnatal viability and nuclear positioning in skeletal muscle.
Volume: 216
Issue: 7
Pages: 1915-1924
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Publication
20457914 | J:160544
First Author: Kim CE
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: A molecular mechanism underlying the neural-specific defect in torsinA mutant mice.
Volume: 107
Issue: 21
Pages: 9861-6
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Publication
28462915 | J:250385
 
First Author: Gorelik A
Year: 2017
Journal: Nat Commun
Title: Developmental activities of the complement pathway in migrating neurons.
Volume: 8
Pages: 15096
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Publication
33514739 | J:302139
First Author: Ramirez-Martinez A
Year: 2021
Journal: Nat Commun
Title: The nuclear envelope protein Net39 is essential for muscle nuclear integrity and chromatin organization.
Volume: 12
Issue: 1
Pages: 690
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Publication
29867343 | J:265671
 
First Author: Gorelik A
Year: 2018
Journal: Front Mol Neurosci
Title: Complement C3 Affects Rac1 Activity in the Developing Brain.
Volume: 11
Pages: 150
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Publication
22116031 | J:178993
First Author: Kim Y
Year: 2011
Journal: Science
Title: Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells.
Volume: 334
Issue: 6063
Pages: 1706-10
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Publication
- | J:233450
     
First Author: Nam K-H
Year: 2016
Journal: MGI Direct Data Submission
Title: Direct Data Submission for Alleles from the KRIBB Institute
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Publication
37067297 | J:339839
First Author: Ross JA
Year: 2023
Journal: Cardiovasc Res
Title: Lem2 is essential for cardiac development by maintaining nuclear integrity.
Volume: 119
Issue: 11
Pages: 2074-2088
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Publication
27434733 | J:238763
First Author: Choo HJ
Year: 2016
Journal: Stem Cells
Title: Karyopherin Alpha 1 Regulates Satellite Cell Proliferation and Survival by Modulating Nuclear Import.
Volume: 34
Issue: 11
Pages: 2784-2797
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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HT Experiment
E-GEOD-6399 | Transcription profiling of mouse heart from Emd KO and controls
Series Id: GSE6399
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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DO Term
DOID:0070246 | X-linked Emery-Dreifuss muscular dystrophy 1
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GO Term
GO:0160045 | TMEM240-body
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Publication
24254699 | J:317344
First Author: Dietrich M
Year: 2014
Journal: J Alzheimers Dis
Title: Alzheimer's disease-like impaired cognition in endothelial-specific megalin-null mice.
Volume: 39
Issue: 4
Pages: 711-7
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Publication
28143489 | J:317345
First Author: Bartolome F
Year: 2017
Journal: J Neuroinflammation
Title: Obesity and neuroinflammatory phenotype in mice lacking endothelial megalin.
Volume: 14
Issue: 1
Pages: 26
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Publication
27398909 | J:238579
First Author: Le HQ
Year: 2016
Journal: Nat Cell Biol
Title: Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment.
Volume: 18
Issue: 8
Pages: 864-75
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Publication
26190113 | J:232524
First Author: Roccaro AM
Year: 2015
Journal: Cell Rep
Title: CXCR4 Regulates Extra-Medullary Myeloma through Epithelial-Mesenchymal-Transition-like Transcriptional Activation.
Volume: 12
Issue: 4
Pages: 622-35
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Protein Coding Gene
MGI:3648074 | Tmem240
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
26500056 | J:234308
First Author: Silginer M
Year: 2016
Journal: Oncogene
Title: The aryl hydrocarbon receptor links integrin signaling to the TGF-β pathway.
Volume: 35
Issue: 25
Pages: 3260-71
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Publication
31937343 | J:297931
First Author: Bartolome F
Year: 2020
Journal: J Neuroinflammation
Title: Endothelial-specific deficiency of megalin in the brain protects mice against high-fat diet challenge.
Volume: 17
Issue: 1
Pages: 22
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Publication
22647877 | J:212654
First Author: Schober T
Year: 2012
Journal: Circ Res
Title: Myofilament Ca sensitization increases cytosolic Ca binding affinity, alters intracellular Ca homeostasis, and causes pause-dependent Ca-triggered arrhythmia.
Volume: 111
Issue: 2
Pages: 170-9
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Publication
19033660 | J:144735
First Author: Baudenbacher F
Year: 2008
Journal: J Clin Invest
Title: Myofilament Ca2+ sensitization causes susceptibility to cardiac arrhythmia in mice.
Volume: 118
Issue: 12
Pages: 3893-903
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Publication
23896226 | J:225393
 
First Author: Stöhr A
Year: 2013
Journal: J Mol Cell Cardiol
Title: Contractile abnormalities and altered drug response in engineered heart tissue from Mybpc3-targeted knock-in mice.
Volume: 63
Pages: 189-98
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Publication
14519438 | J:307943
First Author: Burkart EM
Year: 2003
Journal: J Mol Cell Cardiol
Title: Altered signaling surrounding the C-lobe of cardiac troponin C in myofilaments containing an alpha-tropomyosin mutation linked to familial hypertrophic cardiomyopathy.
Volume: 35
Issue: 10
Pages: 1285-93
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Publication
10080180 | J:53436
First Author: Bonne G
Year: 1999
Journal: Nat Genet
Title: Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy.
Volume: 21
Issue: 3
Pages: 285-8
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Publication
18515207 | J:137910
First Author: Saito K
Year: 2008
Journal: Bone
Title: Amelogenin binds to both heparan sulfate and bone morphogenetic protein 2 and pharmacologically suppresses the effect of noggin.
Volume: 43
Issue: 2
Pages: 371-6
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Publication
25758355 | J:319129
First Author: Mlih M
Year: 2015
Journal: Mol Cell Biochem
Title: Na(+)/H (+) exchanger isoform 1 induced osteopontin expression in cardiomyocytes involves NFAT3/Gata4.
Volume: 404
Issue: 1-2
Pages: 211-20
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Protein Domain
IPR003887 | LEM_dom
Type: Domain
Description: The LEM (LAP2, emerin, MAN1) domain is a globular module of approximately 40amino acids, which is mostly found in the nucleoplasmic portions of metazoaninner nuclear membrane proteins. The LEM domain has been shown to mediatebinding to BAF (barrier-to-autointegration factor) and BAF-DNA complexes. BAFdimers bind to double-stranded DNA non-specifically and thereby bridge DNAmolecules to form a large, discrete nucleoprotein complex [, ].The resolution of the solution structure of the LEM domain reveals that it iscomposed of a three-residue N-terminal helical turn and two large parallelalpha helices interacting through a set of conserved hydrophobic amino acids. The two helices, which are connected by a long loop are oriented at an angle of ~45 degree [, ].Proteins known to contain a LEM domain include:Vertebrate inner nuclear membrane protein MAN1. Vertebrate lamina-associated polypeptide 2 (LAP2) or thymopoietin. Mammalian emerin (EMD). In human, defects in EMD are a cause of X-linked Emery-Dreifuss muscular dystrophy (X-EDMD), an X-linked disorder, characterised by early contractures, muscle wasting and weakness and cardiomyopathy.Xenopus laevis Smad1 antagonistic effector (SANE).Drosophila melanogaster otefin (OTE).Caenorhabditis elegans W01G7.5 protein.
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Protein
Q14C37
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: false
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Protein
A0A087WR04
Organism: Mus musculus/domesticus
Length: 69  
Fragment?: false
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Protein
Q78WP6
Organism: Mus musculus/domesticus
Length: 277  
Fragment?: true
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Protein
A0A087WR92
Organism: Mus musculus/domesticus
Length: 101  
Fragment?: false
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Protein
A0A087WQH1
Organism: Mus musculus/domesticus
Length: 203  
Fragment?: false
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Protein
A0A087WPB5
Organism: Mus musculus/domesticus
Length: 70  
Fragment?: false
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Protein
Q61033
Organism: Mus musculus/domesticus
Length: 693  
Fragment?: false
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Protein
Q61029
Organism: Mus musculus/domesticus
Length: 452  
Fragment?: false
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Protein
Q3U955
Organism: Mus musculus/domesticus
Length: 452  
Fragment?: false
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Protein
Q3U7B3
Organism: Mus musculus/domesticus
Length: 452  
Fragment?: false
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Protein
Q3TNH0
Organism: Mus musculus/domesticus
Length: 412  
Fragment?: false
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Protein
Q3UR33
Organism: Mus musculus/domesticus
Length: 452  
Fragment?: false
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Protein
I7HJS1
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Publication
11435115 | -
First Author: Laguri C
Year: 2001
Journal: Structure
Title: Structural characterization of the LEM motif common to three human inner nuclear membrane proteins.
Volume: 9
Issue: 6
Pages: 503-11
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Publication
11500367 | -
First Author: Cai M
Year: 2001
Journal: EMBO J
Title: Solution structure of the constant region of nuclear envelope protein LAP2 reveals two LEM-domain structures: one binds BAF and the other binds DNA.
Volume: 20
Issue: 16
Pages: 4399-407
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Protein
Q6DVA0
Organism: Mus musculus/domesticus
Length: 511  
Fragment?: false
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Protein
O08579
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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Protein
B7FAU5
Organism: Mus musculus/domesticus
Length: 170  
Fragment?: false
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•
Protein
Q3THM8
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: false
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•
•
•
•
Protein
A2AM95
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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•
•
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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