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Search results 101 to 192 out of 192 for Erp44

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0.019s
Type Details Score
GXD Expression
Probe: MGI:7493392
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7493443
Age: postnatal week 3
Image: 4I
Note: High expression in outer epicardial region and epicardial/myocardial border.
Specimen Label: 4I
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:7493392
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7493443
Age: postnatal adult
Image: 4J
Specimen Label: 4J
Detected: true
Specimen Num: 15
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7493438
Age: postnatal day 1
Image: 4D lacZ P1
Note: Authors report a very specific expression pattern during maturation of heart.
Specimen Label: 4D lacZ P1
Detected: true
Specimen Num: 25
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1603911
Pattern: Not Specified
Stage: TS11
Assay Id: MGI:7493438
Age: embryonic day 7.5
Image: 4A +/- 7.5 dpc
Note: Expression in earliest stages.
Specimen Label: 4A +/- 7.5 dpc
Detected: true
Specimen Num: 16
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7493438
Age: embryonic day 9.5
Image: 4A +/- 9.5 dpc
Specimen Label: 4A +/- 9.5 dpc
Detected: true
Specimen Num: 17
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1603917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7493438
Age: embryonic day 10.5
Image: 4A +/- 10.5 dpc
Specimen Label: 4A +/- 10.5 dpc
Detected: true
Specimen Num: 18
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7493438
Age: embryonic day 12.5
Image: 4A +/- 12.5 dpc
Note: Expression remained high through E12.5.
Specimen Label: 4A +/- 12.5 dpc
Detected: true
Specimen Num: 19
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7493438
Age: embryonic day 12.5
Image: 4L (right)
Specimen Label: 4L (right)
Detected: true
Specimen Num: 28
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1871923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_02
Specimen Label: euxassay_001975_02
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1871923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_03
Specimen Label: euxassay_001975_03
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1871923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_04
Specimen Label: euxassay_001975_04
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1871923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_05
Specimen Label: euxassay_001975_05
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1871923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_06
Specimen Label: euxassay_001975_06
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1871923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_22
Specimen Label: euxassay_001975_22
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1871923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_23
Specimen Label: euxassay_001975_23
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1871923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_24
Specimen Label: euxassay_001975_24
Detected: true
Specimen Num: 18
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7493438
Age: postnatal month 6
Image: 2 LIVER
Specimen Label: 2 LIVER
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:7493392
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-27
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1658928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7493443
Age: postnatal week 12
Note: Expression in epicardium signicantly higher to myocardium
Specimen Label: Epicardium +/+ not shown
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:7493392
Assay Type: Immunohistochemistry
Annotation Date: 2023-06-27
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1658928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7493443
Age: postnatal week 12
Note: Expression in epicardium signficantly lower in heterozygote compared to wild type.
Specimen Label: Epicardium +/- not shown
Detected: true
Specimen Num: 9
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7493438
Age: postnatal month 6
Image: 2 PANCREAS
Specimen Label: 2 PANCREAS
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7493438
Age: postnatal month 6
Image: 2 THYMUS
Specimen Label: 2 THYMUS
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_06
Specimen Label: euxassay_001975_06
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_07
Specimen Label: euxassay_001975_07
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_08
Specimen Label: euxassay_001975_08
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_09
Specimen Label: euxassay_001975_09
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_10
Specimen Label: euxassay_001975_10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_17
Specimen Label: euxassay_001975_17
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_18
Specimen Label: euxassay_001975_18
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_19
Specimen Label: euxassay_001975_19
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_20
Specimen Label: euxassay_001975_20
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1794223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_21
Specimen Label: euxassay_001975_21
Detected: true
Specimen Num: 15
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1832128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7493438
Age: postnatal month 6
Image: 2 BLADDER
Specimen Label: 2 BLADDER
Detected: true
Specimen Num: 8
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3511228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7493438
Age: postnatal month 6
Image: 2 FAT
Specimen Label: 2 FAT
Detected: true
Specimen Num: 15
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7493438
Age: postnatal month 6
Image: 2 SKIN
Specimen Label: 2 SKIN
Detected: true
Specimen Num: 14
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7493438
Age: postnatal month 6
Image: 2 STOMACH
Specimen Label: 2 STOMACH
Detected: true
Specimen Num: 11
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7493438
Age: postnatal month 6
Image: 2 ILIUM
Specimen Label: 2 ILIUM
Detected: true
Specimen Num: 6
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7493438
Age: postnatal month 6
Image: 2 UTERUS
Specimen Label: 2 UTERUS
Detected: true
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-06-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7493438
Age: postnatal month 6
Image: 2 BRAIN
Specimen Label: 2 BRAIN
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_10
Specimen Label: euxassay_001975_10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:974819
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1791823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824619
Age: embryonic day 14.5
Image: euxassay_001975_11
Specimen Label: euxassay_001975_11
Detected: true
Specimen Num: 10
Publication
First Author: Wei Z
Year: 2013
Journal: J Biol Chem
Title: C1q/tumor necrosis factor-related protein 11 (CTRP11), a novel adipose stroma-derived regulator of adipogenesis.
Volume: 288
Issue: 15
Pages: 10214-29
Publication
First Author: Wang ZV
Year: 2007
Journal: Mol Cell Biol
Title: Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention.
Volume: 27
Issue: 10
Pages: 3716-31
Publication
First Author: Turano C
Year: 2002
Journal: J Cell Physiol
Title: Proteins of the PDI family: unpredicted non-ER locations and functions.
Volume: 193
Issue: 2
Pages: 154-63
Publication
First Author: Hedlund E
Year: 2004
Journal: J Neurosci Res
Title: Identification of a Hoxd10-regulated transcriptional network and combinatorial interactions with Hoxa10 during spinal cord development.
Volume: 75
Issue: 3
Pages: 307-19
Publication
First Author: Lo JC
Year: 2012
Journal: PLoS Genet
Title: RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.
Volume: 8
Issue: 10
Pages: e1002969
Publication      
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
Publication      
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
Publication      
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
Publication
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Wang L
Year: 2008
Journal: EMBO Rep
Title: Crystal structure of human ERp44 shows a dynamic functional modulation by its carboxy-terminal tail.
Volume: 9
Issue: 7
Pages: 642-7
Protein
Organism: Mus musculus/domesticus
Length: 406  
Fragment?: false
Interaction Experiment
Description: SUMOylation of ERp44 enhances Ero1? ER retention contributing to the pathogenesis of obesity and insulin resistance.
Publication
First Author: Anelli T
Year: 2003
Journal: EMBO J
Title: Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44.
Volume: 22
Issue: 19
Pages: 5015-22
Protein Domain
Type: Domain
Description: This entry represents the first redox inactive TRX-like domain b found in endoplasmic reticulum resident protein 44 (ERp44). ERp44 is an endoplasmic reticulum (ER)-resident protein, induced during stress, and involved in thiol-mediated ER retention. It contains an N-terminal TRX domain with a CXFS motif followed by two redox inactive TRX-like domains, homologous to the b and b' domains of PDI. Through the formation of reversible mixed disulfides, ERp44 mediates the ER localization of Ero1alpha, a protein that oxidizes protein disulfide isomerases into their active form [, ]. ERp44 also prevents the secretion of unassembled cargo protein with unpaired cysteines. ERp44 also modulates the activity of inositol 1,4,5-triphosphate type I receptor (IP3R1), an intracellular channel protein that mediates calcium release from the ER to the cytosol []. Similar to PDI, the b domain of ERp44 is likely involved in binding to substrates.
Publication
First Author: Watanabe S
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Structural basis of pH-dependent client binding by ERp44, a key regulator of protein secretion at the ER-Golgi interface.
Volume: 114
Issue: 16
Pages: E3224-E3232
Protein Domain
Type: Domain
Description: ERp44 is an endoplasmic reticulum (ER)-resident protein that retrieves some ER-resident enzymes and immature oligomers of secretory proteins from the Golgi []. It is composed of three thioredoxin (Trx)-like domains (a, b,and b'), followed by a C-terminal extension (C tail). Domain a contains a rather unique CRFS motif. The cysteine in this motif (Cys29) is known to form mixed disulfide bonds with client proteins to promote their thiol-dependent retention. Domain a is followed by two redox inactive Trx-like domains, b and b' []. Interestingly, the interactions between ERp44 and client proteins are pH-dependent []. This entry represents domain b', the second redox inactive TRX-like domain of ERp44.
Protein
Organism: Mus musculus/domesticus
Length: 406  
Fragment?: false