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Search results 101 to 187 out of 187 for Exoc2

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11940
Specimen Label: GUDMAP:11940
Detected: true
Specimen Num: 3
•
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:6190
Specimen Label: GUDMAP:6190
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11847
Specimen Label: GUDMAP:11847
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6890390
Assay Type: RNA in situ
Annotation Date: 2022-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7255031
Age: embryonic day 13.5
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
Probe: MGI:6890390
Assay Type: RNA in situ
Annotation Date: 2022-03-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1736221
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7255031
Age: embryonic day 13.5
Image: 3D
Note: Expression was increased throughout the anterior-posterior axis of the palatal shelves, with particularly strong upregulation in the posterior region.
Specimen Label: 3D
Detected: true
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
Probe: MGI:6890390
Assay Type: RNA in situ
Annotation Date: 2022-03-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1736221
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7255031
Age: embryonic day 13.5
Image: 3E
Note: Expression was increased throughout the anterior-posterior axis of the palatal shelves, with particularly strong upregulation in the posterior region.
Specimen Label: 3E
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:6890390
Assay Type: RNA in situ
Annotation Date: 2022-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736221
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7255031
Age: embryonic day 13.5
Image: 5C
Specimen Label: 5C
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6890390
Assay Type: RNA in situ
Annotation Date: 2022-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1736221
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7255031
Age: embryonic day 13.5
Image: 5C'
Note: Expression was increased in the posterior palatal shelves in mutant compared with wild type.
Specimen Label: 5C'
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:6190
Specimen Label: GUDMAP:6190
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11847
Specimen Label: GUDMAP:11847
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11940
Specimen Label: GUDMAP:11940
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:6190
Specimen Label: GUDMAP:6190
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11847
Specimen Label: GUDMAP:11847
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11940
Specimen Label: GUDMAP:11940
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754021
Stage: TS21
Assay Id: MGI:3508265
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754027
Stage: TS27
Assay Id: MGI:3508265
Age: postnatal newborn
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:6190
Specimen Label: GUDMAP:6190
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11847
Specimen Label: GUDMAP:11847
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11940
Specimen Label: GUDMAP:11940
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280927
Stage: TS27
Assay Id: MGI:3508265
Age: postnatal newborn
Note: The tissue was olfactory epithelium and/or bulb.
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267921
Stage: TS21
Assay Id: MGI:3508265
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3267927
Stage: TS27
Assay Id: MGI:3508265
Age: postnatal newborn
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:6190
Specimen Label: GUDMAP:6190
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11847
Specimen Label: GUDMAP:11847
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11940
Specimen Label: GUDMAP:11940
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11940
Specimen Label: GUDMAP:11940
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757721
Stage: TS21
Assay Id: MGI:3508265
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3508265
Age: postnatal newborn
Specimen Label: 2
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:6190
Specimen Label: GUDMAP:6190
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11847
Specimen Label: GUDMAP:11847
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11940
Specimen Label: GUDMAP:11940
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:3506836
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5539806
Age: embryonic day 15.5
Image: GUDMAP:11940
Specimen Label: GUDMAP:11940
Detected: true
Specimen Num: 3
•
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•
Publication
20579884 | J:163778
First Author: Nichols CD
Year: 2010
Journal: Curr Biol
Title: Salmonella-directed recruitment of new membrane to invasion foci via the host exocyst complex.
Volume: 20
Issue: 14
Pages: 1316-20
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Publication
18480549 | J:150915
First Author: Saito T
Year: 2008
Journal: Biomed Res
Title: Involvement of Exoc3l, a protein structurally related to the exocyst subunit Sec6, in insulin secretion.
Volume: 29
Issue: 2
Pages: 85-91
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Publication
26582389 | J:234047
First Author: Seixas C
Year: 2016
Journal: Mol Biol Cell
Title: Arl13b and the exocyst interact synergistically in ciliogenesis.
Volume: 27
Issue: 2
Pages: 308-20
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Publication
22420621 | J:320331
First Author: Heider MR
Year: 2012
Journal: Traffic
Title: Exorcising the exocyst complex.
Volume: 13
Issue: 7
Pages: 898-907
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Publication
32040930 | J:287549
First Author: Xu J
Year: 2020
Journal: J Dent Res
Title: Genome-wide Identification of Foxf2 Target Genes in Palate Development.
Volume: 99
Issue: 4
Pages: 463-471
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Publication
- | J:279207
     
First Author: Mager J
Year: 2019
Journal: MGI Direct Data Submission
Title: A Catalog of Early Lethal KOMP Phenotypes
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Publication
20412781 | J:140465
First Author: Guo G
Year: 2010
Journal: Dev Cell
Title: Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.
Volume: 18
Issue: 4
Pages: 675-85
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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•
•
Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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•
•
•
Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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•
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•
Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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•
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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•
•
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein Domain
IPR029175 | EXOC2/Sec5
Type: Family
Description: This entry includes Sec5 from yeasts and EXOC2 from animals. In S. cerevisiae, Sec5 is an essential component of the exocyst complex, which is composed of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84 []. The exocyst complex tethers post-Golgi secretory vesicles to the plasma membrane before soluble NSF attachment protein receptor (SNARE)-mediated membrane fusion [].In mammals, active form (GTP-bound) of Ral GTPase interacts with EXOC2 and Exo84 and regulates the assembly interface of a full octameric exocyst complex []. Similar to yeast exocyst, the mammalian exocyst has been directly linked to post-Golgi targeting of secretory vesicles to discreet membrane sites [].
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Protein
Q8K2J3
Organism: Mus musculus/domesticus
Length: 636  
Fragment?: true
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Publication
21997494 | -
First Author: Liu J
Year: 2012
Journal: Protoplasma
Title: The exocyst complex in exocytosis and cell migration.
Volume: 249
Issue: 3
Pages: 587-97
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Publication
7615633 | -
First Author: TerBush DR
Year: 1995
Journal: J Cell Biol
Title: Sec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae.
Volume: 130
Issue: 2
Pages: 299-312
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Protein Domain
IPR039481 | EXOC2/Sec5_N_dom
Type: Domain
Description: This entry represent a domain found at the N terminus of Sec5 from budding yeasts and EXOC2/VPS51 from animals.In S. cerevisiae, Sec5 is an essential component of the exocyst complex, which is composed of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84 []. The exocyst complex tethers post-Golgi secretory vesicles to the plasma membrane before soluble NSF attachment protein receptor (SNARE)-mediated membrane fusion [].In mammals, active form (GTP-bound) of Ral GTPase interacts with EXOC2 and Exo84 and regulates the assembly interface of a full octameric exocyst complex []. Similar to yeast exocyst, the mammalian exocyst has been directly linked to post-Golgi targeting of secretory vesicles to discreet membrane sites [].
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Publication
14525976 | -
First Author: Moskalenko S
Year: 2003
Journal: J Biol Chem
Title: Ral GTPases regulate exocyst assembly through dual subunit interactions.
Volume: 278
Issue: 51
Pages: 51743-8
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Protein
Q9D4H1
Organism: Mus musculus/domesticus
Length: 924  
Fragment?: false
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Protein
Q8BSK6
Organism: Mus musculus/domesticus
Length: 258  
Fragment?: false
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Protein
Q8C984
Organism: Mus musculus/domesticus
Length: 223  
Fragment?: false
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Protein
Q3UVL4
Organism: Mus musculus/domesticus
Length: 782  
Fragment?: false
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