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Search results 101 to 200 out of 329 for Fbxw7

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Type Details Score
Publication
First Author: Fukushima H
Year: 2012
Journal: Cell Rep
Title: SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction.
Volume: 1
Issue: 5
Pages: 434-43
Publication
First Author: Wang L
Year: 2020
Journal: Cell Metab
Title: FBW7 Mediates Senescence and Pulmonary Fibrosis through Telomere Uncapping.
Volume: 32
Issue: 5
Pages: 860-877.e9
Publication
First Author: Li H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Genetic Deletion of Fbw7 in the mouse intestinal epithelium aggravated dextran sodium sulfate-induced colitis by modulating the inflammatory response of NF-κB pathway.
Volume: 498
Issue: 4
Pages: 869-876
Publication
First Author: Cai Z
Year: 2024
Journal: Cell Death Dis
Title: Selective deletion of E3 ubiquitin ligase FBW7 in VE-cadherin-positive cells instigates diffuse large B-cell lymphoma in mice in vivo.
Volume: 15
Issue: 3
Pages: 212
Publication
First Author: Li J
Year: 2002
Journal: J Neurochem
Title: SEL-10 interacts with presenilin 1, facilitates its ubiquitination, and alters A-beta peptide production.
Volume: 82
Issue: 6
Pages: 1540-8
Publication
First Author: Wang R
Year: 2013
Journal: Cell Res
Title: FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation.
Volume: 23
Issue: 6
Pages: 803-19
Publication  
First Author: Shen Y
Year: 2019
Journal: Neurobiol Dis
Title: Smooth muscle cell-specific knockout of FBW7 exacerbates intracranial atherosclerotic stenosis.
Volume: 132
Pages: 104584
Publication
First Author: Feng C
Year: 2021
Journal: Immunology
Title: Critical roles of the E3 ubiquitin ligase FBW7 in B-cell response and the pathogenesis of experimental autoimmune arthritis.
Volume: 164
Issue: 3
Pages: 617-636
GXD Expression      
Probe: MGI:3690954
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3691001
Age: embryonic day 1.0,2.5
Specimen Label: C
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:3690954
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3691001
Age: embryonic day 1.0,2.5
Specimen Label: C
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:3690954
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3691001
Age: embryonic day 1.0,2.5
Specimen Label: C
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:3690954
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3691001
Age: embryonic day 1.0,2.5
Specimen Label: C
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:3690954
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3691001
Age: embryonic day 3.5
Specimen Label: B
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:3690954
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3691001
Age: embryonic day 3.5
Specimen Label: B
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:3690954
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:3691001
Age: embryonic day 0.0,0.5
Specimen Label: 1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3690954
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:3691001
Age: embryonic day 0.0,0.5
Specimen Label: 1
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3690954
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3575528
Stage: TS28
Assay Id: MGI:3691001
Age: embryonic day 0.0,0.5
Specimen Label: 1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3690954
Assay Type: RT-PCR
Annotation Date: 2006-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360411
Stage: TS01
Assay Id: MGI:3691001
Age: embryonic day 0.0,0.5
Specimen Label: 1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6501008
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6501018
Age: postnatal week 8
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6501008
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6501018
Age: postnatal week 8
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6501008
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6501018
Age: postnatal week 8
Specimen Label: -/-
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:6501008
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271628
Stage: TS28
Assay Id: MGI:6501018
Age: postnatal week 8
Specimen Label: +/+
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6501008
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271628
Stage: TS28
Assay Id: MGI:6501018
Age: postnatal week 8
Specimen Label: +/-
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6501008
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271628
Stage: TS28
Assay Id: MGI:6501018
Age: postnatal week 8
Specimen Label: -/-
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6501010
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6501020
Age: postnatal week 8
Specimen Label: +/+
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6501010
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6501020
Age: postnatal week 8
Specimen Label: +/-
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6501010
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6501020
Age: postnatal week 8
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6501010
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271628
Stage: TS28
Assay Id: MGI:6501020
Age: postnatal week 8
Specimen Label: +/+
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6501010
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271628
Stage: TS28
Assay Id: MGI:6501020
Age: postnatal week 8
Specimen Label: +/-
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:6501010
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271628
Stage: TS28
Assay Id: MGI:6501020
Age: postnatal week 8
Specimen Label: -/-
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6501009
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6501021
Age: postnatal week 8
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6501009
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6501021
Age: postnatal week 8
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6501009
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6501021
Age: postnatal week 8
Specimen Label: -/-
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6501009
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3271628
Stage: TS28
Assay Id: MGI:6501021
Age: postnatal week 8
Specimen Label: +/+
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6501009
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3271628
Stage: TS28
Assay Id: MGI:6501021
Age: postnatal week 8
Specimen Label: +/-
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6501009
Assay Type: RT-PCR
Annotation Date: 2021-01-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3271628
Stage: TS28
Assay Id: MGI:6501021
Age: postnatal week 8
Specimen Label: -/-
Detected: false
Specimen Num: 6
GXD Expression    
Probe: MGI:7427604
Assay Type: RT-PCR
Annotation Date: 2023-01-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1685326
Stage: TS26
Assay Id: MGI:7427621
Age: embryonic day 18.5
Image: 1
Specimen Label: control
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5540092
Age: embryonic day 15.5
Image: GUDMAP:6679
Specimen Label: GUDMAP:6679
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4422610
Assay Type: RNA in situ
Annotation Date: 2023-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7526598
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2845723
Stage: TS23
Assay Id: MGI:5540092
Age: embryonic day 15.5
Image: GUDMAP:6679
Specimen Label: GUDMAP:6679
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1795023
Stage: TS23
Assay Id: MGI:5540092
Age: embryonic day 15.5
Image: GUDMAP:6679
Specimen Label: GUDMAP:6679
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:3509931
Age: embryonic day 10.5
Image: 1 - left embryo
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Label: 1 - left embryo
Specimen Num: 1
GXD Expression  
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1647018
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:3509931
Age: embryonic day 10.5
Image: 2 - right embryo
Note: Authors stated that in some instances they could not determine expression levels with certainty.
Specimen Label: 2 - right embryo
Specimen Num: 2
GXD Expression  
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2854023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540092
Age: embryonic day 15.5
Image: GUDMAP:6679
Specimen Label: GUDMAP:6679
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2762123
Stage: TS23
Assay Id: MGI:5540092
Age: embryonic day 15.5
Image: GUDMAP:6679
Specimen Label: GUDMAP:6679
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540092
Age: embryonic day 15.5
Image: GUDMAP:6679
Specimen Label: GUDMAP:6679
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4422610
Assay Type: RNA in situ
Annotation Date: 2023-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7526598
Age: embryonic day 14.5
Note: Ventricular zone expression was greater than in the cortical plate.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2851823
Stage: TS23
Assay Id: MGI:5540092
Age: embryonic day 15.5
Image: GUDMAP:6679
Specimen Label: GUDMAP:6679
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2760523
Stage: TS23
Assay Id: MGI:5540092
Age: embryonic day 15.5
Image: GUDMAP:6679
Specimen Label: GUDMAP:6679
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2852723
Stage: TS23
Assay Id: MGI:5540092
Age: embryonic day 15.5
Image: GUDMAP:6679
Specimen Label: GUDMAP:6679
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540092
Age: embryonic day 15.5
Image: GUDMAP:6679
Specimen Label: GUDMAP:6679
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2850023
Stage: TS23
Assay Id: MGI:5540092
Age: embryonic day 15.5
Image: GUDMAP:6679
Specimen Label: GUDMAP:6679
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3507144
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5540092
Age: embryonic day 15.5
Image: GUDMAP:6679
Specimen Label: GUDMAP:6679
Detected: true
Specimen Num: 1
Publication  
First Author: Wang C
Year: 2020
Journal: Redox Biol
Title: Myeloid FBW7 deficiency disrupts redox homeostasis and aggravates dietary-induced insulin resistance.
Volume: 37
Pages: 101688
Publication
First Author: Takada M
Year: 2017
Journal: Oncotarget
Title: EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor.
Volume: 8
Issue: 4
Pages: 6787-6795
Publication
First Author: Biswas M
Year: 2011
Journal: J Biol Chem
Title: The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis.
Volume: 286
Issue: 45
Pages: 39282-9
Publication
First Author: Schülein-Völk C
Year: 2014
Journal: Cell Rep
Title: Dual regulation of Fbw7 function and oncogenic transformation by Usp28.
Volume: 9
Issue: 3
Pages: 1099-109
Publication
First Author: Inuzuka H
Year: 2011
Journal: Nature
Title: SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
Volume: 471
Issue: 7336
Pages: 104-9
Publication
First Author: Sancho R
Year: 2014
Journal: Cell Stem Cell
Title: Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells.
Volume: 15
Issue: 2
Pages: 139-53
Publication
First Author: Hoshikawa S
Year: 2020
Journal: FASEB J
Title: Phosphorylation-dependent osterix degradation negatively regulates osteoblast differentiation.
Volume: 34
Issue: 11
Pages: 14930-14945
Publication
First Author: Min SH
Year: 2012
Journal: Mol Cell
Title: Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.
Volume: 46
Issue: 6
Pages: 771-83
Publication
First Author: Fukushima H
Year: 2017
Journal: Mol Cell
Title: NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis.
Volume: 68
Issue: 4
Pages: 645-658.e5
Publication
First Author: Mo JS
Year: 2011
Journal: J Cell Sci
Title: Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase.
Volume: 124
Issue: Pt 1
Pages: 100-12
Publication  
First Author: Balamurugan K
Year: 2013
Journal: Nat Commun
Title: FBXW7α attenuates inflammatory signalling by downregulating C/EBPδ and its target gene Tlr4.
Volume: 4
Pages: 1662
Publication
First Author: Grim JE
Year: 2012
Journal: Mol Cell Biol
Title: Fbw7 and p53 cooperatively suppress advanced and chromosomally unstable intestinal cancer.
Volume: 32
Issue: 11
Pages: 2160-7
Publication
First Author: Ramezani-Rad P
Year: 2020
Journal: J Immunol
Title: E3 Ubiquitin Ligase Fbw7 Regulates the Survival of Mature B Cells.
Volume: 204
Issue: 6
Pages: 1535-1542
Publication
First Author: Sun Y
Year: 2014
Journal: Mol Cell Biol
Title: The canonical wnt signal restricts the glycogen synthase kinase 3/fbw7-dependent ubiquitination and degradation of eya1 phosphatase.
Volume: 34
Issue: 13
Pages: 2409-17
Publication
First Author: Xu Y
Year: 2014
Journal: Oncogene
Title: Fbw7-dependent cyclin E regulation ensures terminal maturation of bone marrow erythroid cells by restraining oxidative metabolism.
Volume: 33
Issue: 24
Pages: 3161-71
Publication
First Author: Reavie L
Year: 2013
Journal: Cancer Cell
Title: Regulation of c-Myc ubiquitination controls chronic myelogenous leukemia initiation and progression.
Volume: 23
Issue: 3
Pages: 362-75
Publication
First Author: Bixel MG
Year: 2024
Journal: Nat Commun
Title: Angiogenesis is uncoupled from osteogenesis during calvarial bone regeneration.
Volume: 15
Issue: 1
Pages: 4575
Publication
First Author: Lolla P
Year: 2021
Journal: Biochem J
Title: Inositol pyrophosphates promote MYC polyubiquitination by FBW7 to regulate cell survival.
Volume: 478
Issue: 8
Pages: 1647-1661
Publication
First Author: Duhamel S
Year: 2016
Journal: Cell Cycle
Title: Deregulated ERK1/2 MAP kinase signaling promotes aneuploidy by a Fbxw7β-Aurora A pathway.
Volume: 15
Issue: 12
Pages: 1631-42
Publication
First Author: Maskey D
Year: 2015
Journal: EMBO J
Title: Cell cycle-dependent ubiquitylation and destruction of NDE1 by CDK5-FBW7 regulates ciliary length.
Volume: 34
Issue: 19
Pages: 2424-40
Publication
First Author: Xiao D
Year: 2016
Journal: Mol Cell
Title: Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
Volume: 64
Issue: 3
Pages: 493-506
Publication
First Author: Li L
Year: 2023
Journal: Dev Cell
Title: Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination.
Volume: 58
Issue: 21
Pages: 2275-2291.e6
Publication
First Author: Diefenbacher ME
Year: 2015
Journal: Cancer Res
Title: Usp28 counteracts Fbw7 in intestinal homeostasis and cancer.
Volume: 75
Issue: 7
Pages: 1181-6
Publication
First Author: Sancho R
Year: 2010
Journal: Gastroenterology
Title: F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.
Volume: 139
Issue: 3
Pages: 929-41
Publication
First Author: Sancho R
Year: 2013
Journal: PLoS Biol
Title: Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions.
Volume: 11
Issue: 6
Pages: e1001586
Publication
First Author: Siu KT
Year: 2014
Journal: Mol Cell Biol
Title: Chromosome instability underlies hematopoietic stem cell dysfunction and lymphoid neoplasia associated with impaired Fbw7-mediated cyclin E regulation.
Volume: 34
Issue: 17
Pages: 3244-58
Publication
First Author: Zheng B
Year: 2018
Journal: Biochim Biophys Acta
Title: Regulatory crosstalk between KLF5, miR-29a and Fbw7/CDC4 cooperatively promotes atherosclerotic development.
Volume: 1864
Issue: 2
Pages: 374-386
Publication
First Author: Khan OM
Year: 2018
Journal: J Clin Invest
Title: The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.
Volume: 128
Issue: 4
Pages: 1326-1337
Publication    
First Author: Ruiz EJ
Year: 2021
Journal: Elife
Title: USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma.
Volume: 10
Publication
First Author: Kitagawa K
Year: 2014
Journal: Mol Cell Biol
Title: Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development.
Volume: 34
Issue: 14
Pages: 2732-44
Publication
First Author: Ekholm-Reed S
Year: 2013
Journal: Mol Cell Biol
Title: Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1.
Volume: 33
Issue: 18
Pages: 3627-43
Publication
First Author: Bhaskaran N
Year: 2013
Journal: Mol Cell Biol
Title: Fbw7α and Fbw7γ collaborate to shuttle cyclin E1 into the nucleolus for multiubiquitylation.
Volume: 33
Issue: 1
Pages: 85-97
Publication
First Author: Maruyama S
Year: 2001
Journal: Genomics
Title: Characterization of a mouse gene (Fbxw6) that encodes a homologue of Caenorhabditis elegans SEL-10.
Volume: 78
Issue: 3
Pages: 214-22
Publication
First Author: Ferreira RMM
Year: 2017
Journal: Cell Rep
Title: Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression.
Volume: 21
Issue: 4
Pages: 966-978
Publication
First Author: Kumadaki S
Year: 2011
Journal: J Biol Chem
Title: Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.
Volume: 286
Issue: 47
Pages: 40835-46
Publication
First Author: Romeo SG
Year: 2019
Journal: Nat Cell Biol
Title: Endothelial proteolytic activity and interaction with non-resorbing osteoclasts mediate bone elongation.
Volume: 21
Issue: 4
Pages: 430-441
Publication
First Author: Wang VM
Year: 2019
Journal: Nat Cell Biol
Title: CD9 identifies pancreatic cancer stem cells and modulates glutamine metabolism to fuel tumour growth.
Volume: 21
Issue: 11
Pages: 1425-1435
Publication
First Author: Ehling M
Year: 2013
Journal: Development
Title: Notch controls retinal blood vessel maturation and quiescence.
Volume: 140
Issue: 14
Pages: 3051-61
Publication
First Author: Blaas L
Year: 2016
Journal: Nat Cell Biol
Title: Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours.
Volume: 18
Issue: 12
Pages: 1346-1356
Publication
First Author: Messal HA
Year: 2019
Journal: Nature
Title: Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis.
Volume: 566
Issue: 7742
Pages: 126-130
Publication
First Author: Nakajima T
Year: 2015
Journal: J Biol Chem
Title: Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
Volume: 290
Issue: 16
Pages: 10368-81
Publication  
First Author: Mosleh E
Year: 2020
Journal: Endocrinology
Title: Ins1-Cre and Ins1-CreER Gene Replacement Alleles Are Susceptible To Silencing By DNA Hypermethylation.
Volume: 161
Issue: 8
Publication
First Author: Rocher-Ros V
Year: 2010
Journal: Oncogene
Title: Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7.
Volume: 29
Issue: 20
Pages: 2950-61
Publication
First Author: Ramasamy SK
Year: 2014
Journal: Nature
Title: Endothelial Notch activity promotes angiogenesis and osteogenesis in bone.
Volume: 507
Issue: 7492
Pages: 376-380
Publication
First Author: Mavrakis KJ
Year: 2011
Journal: Nat Genet
Title: A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).
Volume: 43
Issue: 7
Pages: 673-8
Publication
First Author: Bonetti P
Year: 2008
Journal: J Cell Biol
Title: Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gamma.
Volume: 182
Issue: 1
Pages: 19-26
Publication
First Author: Wertz IE
Year: 2011
Journal: Nature
Title: Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
Volume: 471
Issue: 7336
Pages: 110-4