Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3525728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
|
Specimen Label: |
1F KO |
Detected: |
false |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3525728 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
Note: |
Expression is present in GABA-ergic inhibitory neurons. |
Specimen Label: |
1F WT |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1909528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
|
Specimen Label: |
1G KO |
Detected: |
false |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1909528 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
Note: |
Expression is present in GABA-ergic inhibitory neurons. |
Specimen Label: |
1G WT |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3276828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
|
Specimen Label: |
1E KO |
Detected: |
false |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3276828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
Note: |
Expression is present in GABA-ergic inhibitory neurons. |
Specimen Label: |
1E WT |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3278928 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
Note: |
There is no expression in dopaminergic axon fibers projecting to the nucleus accumbens (although there is expression in GABA-ergic inhibitory neurons). |
Specimen Label: |
1I WT lower |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3278928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
|
Specimen Label: |
1H KO |
Detected: |
false |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3278928 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
Note: |
Expression is present in GABA-ergic inhibitory neurons. |
Specimen Label: |
1H WT |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6514419 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-04-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689617 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:6514720 |
Age: |
embryonic day 10.5 |
|
Note: |
Expression was detected in the developing hypothalamus. |
Specimen Label: |
6B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6514419 |
Assay Type: |
RNA in situ |
Annotation Date: |
2021-04-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689617 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:6514720 |
Age: |
embryonic day 10.5 |
|
Note: |
Expression was detected in the developing hypothalamus. |
Specimen Label: |
6D |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3277028 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
|
Specimen Label: |
1C KO |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3277028 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
Note: |
Expression is present in axon bundles that form the mossy fiber pathway. |
Specimen Label: |
1C WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3583628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
Note: |
There is no expression in the somata of dopaminergic neurons. |
Specimen Label: |
1I WT upper |
Detected: |
false |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3527628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
|
Specimen Label: |
1C KO |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3527628 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
Note: |
Expression is present in axon bundles that form the mossy fiber pathway. |
Specimen Label: |
1C WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3525628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
|
Specimen Label: |
1F KO |
Detected: |
false |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3812175 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2008-10-28 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3525628 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:3812194 |
Age: |
postnatal week 12-15 |
|
Note: |
Expression is present in GABA-ergic inhibitory neurons. |
Specimen Label: |
1F WT |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gobé C |
Year: |
2019 |
Journal: |
PLoS Genet |
Title: |
Dual role of DMXL2 in olfactory information transmission and the first wave of spermatogenesis. |
Volume: |
15 |
Issue: |
2 |
Pages: |
e1007909 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
MGC Data curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
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•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
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Title: |
Cyagen Biosciences Website. |
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•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
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Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Okumura F |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis. |
Volume: |
279 |
Issue: |
51 |
Pages: |
53533-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishii H |
Year: |
1999 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors. |
Volume: |
96 |
Issue: |
7 |
Pages: |
3928-33 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
599
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Interaction Experiment |
Description: |
Dendrite Development Regulated by the Schizophrenia-Associated Gene FEZ1 Involves the Ubiquitin Proteasome System. |
|
•
•
•
•
•
|
Publication |
First Author: |
Boguski MS |
Year: |
1993 |
Journal: |
Nat Genet |
Title: |
dbEST--database for "expressed sequence tags". |
Volume: |
4 |
Issue: |
4 |
Pages: |
332-3 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The first member of the FEZ (fasciculation and elongation protein zeta) family identified was unc-76, from C. elegans. The protein is necessary for normal axon fasciculation and is required for axon-axon interactions []. Later, two human homologues, FEZ1 and FEZ2, were identified []. FEZ1 and FEZ2 interact with PKCzeta and have been shown to induce neurite extension of PC12 cells when co-expressed with a constitutively active mutant of PKCzeta []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
125
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
47
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
35
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
McKnight NC |
Year: |
2012 |
Journal: |
EMBO J |
Title: |
Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC. |
Volume: |
31 |
Issue: |
8 |
Pages: |
1931-46 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents short coiled-coil protein (SCOC). In human, SCOC is required for autophagosome formation during amino acid starvation. It forms a starvation-sensitive trimeric complex with UVRAG (UV radiation resistance associated gene) and FEZ1 and may regulate ULK1 and Beclin 1 complex activities []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
392
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
348
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
348
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
322
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
78
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
331
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
375
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
123
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
373
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
169
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
91
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
53
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
167
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
47
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
345
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Bloom L |
Year: |
1997 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation. |
Volume: |
94 |
Issue: |
7 |
Pages: |
3414-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ren J |
Year: |
2016 |
Journal: |
Brain Res |
Title: |
Interaction between DISC1 and CHL1 in regulation of neurite outgrowth. |
Volume: |
1648 |
Issue: |
Pt A |
Pages: |
290-297 |
|
•
•
•
•
•
|