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Search results 101 to 197 out of 197 for Fgd4

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0.026s
Type Details Score
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_04
Specimen Label: euxassay_009166_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_05
Specimen Label: euxassay_009166_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_06
Specimen Label: euxassay_009166_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_18
Specimen Label: euxassay_009166_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_19
Specimen Label: euxassay_009166_19
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1761223
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_10
Specimen Label: euxassay_009166_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1761223
Pattern: Spotted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_13
Specimen Label: euxassay_009166_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_06
Specimen Label: euxassay_009166_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_07
Specimen Label: euxassay_009166_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_17
Specimen Label: euxassay_009166_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_08
Specimen Label: euxassay_009166_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_09
Specimen Label: euxassay_009166_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_10
Specimen Label: euxassay_009166_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_11
Specimen Label: euxassay_009166_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_12
Specimen Label: euxassay_009166_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_13
Specimen Label: euxassay_009166_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_14
Specimen Label: euxassay_009166_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_15
Specimen Label: euxassay_009166_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_16
Specimen Label: euxassay_009166_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_07
Specimen Label: euxassay_009166_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_16
Specimen Label: euxassay_009166_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_17
Specimen Label: euxassay_009166_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_01
Specimen Label: euxassay_009166_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_02
Specimen Label: euxassay_009166_02
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_03
Specimen Label: euxassay_009166_03
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_04
Specimen Label: euxassay_009166_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_05
Specimen Label: euxassay_009166_05
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_06
Specimen Label: euxassay_009166_06
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_07
Specimen Label: euxassay_009166_07
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_08
Specimen Label: euxassay_009166_08
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_09
Specimen Label: euxassay_009166_09
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_10
Specimen Label: euxassay_009166_10
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_11
Specimen Label: euxassay_009166_11
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_12
Specimen Label: euxassay_009166_12
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_13
Specimen Label: euxassay_009166_13
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_14
Specimen Label: euxassay_009166_14
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_15
Specimen Label: euxassay_009166_15
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_16
Specimen Label: euxassay_009166_16
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_17
Specimen Label: euxassay_009166_17
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_18
Specimen Label: euxassay_009166_18
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_19
Specimen Label: euxassay_009166_19
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_20
Specimen Label: euxassay_009166_20
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_21
Specimen Label: euxassay_009166_21
Detected: true
Specimen Num: 21
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_22
Specimen Label: euxassay_009166_22
Detected: true
Specimen Num: 22
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_23
Specimen Label: euxassay_009166_23
Detected: true
Specimen Num: 23
GXD Expression  
Probe: MGI:656535
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4824838
Age: embryonic day 14.5
Image: euxassay_009166_24
Specimen Label: euxassay_009166_24
Detected: true
Specimen Num: 24
Publication
First Author: Dong H
Year: 2007
Journal: Heredity (Edinb)
Title: Quantitative trait loci linked to thalamus and cortex gray matter volumes in BXD recombinant inbred mice.
Volume: 99
Issue: 1
Pages: 62-9
Publication
First Author: van der Weyden L
Year: 2020
Journal: G3 (Bethesda)
Title: A Genome-Wide Screen in Mice To Identify Cell-Extrinsic Regulators of Pulmonary Metastatic Colonisation.
Volume: 10
Issue: 6
Pages: 1869-1877
Publication
First Author: Kenney-Hunt JP
Year: 2006
Journal: Mamm Genome
Title: Quantitative trait loci for body size components in mice.
Volume: 17
Issue: 6
Pages: 526-37
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
Publication        
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: FYVE, RhoGEF and PH domain containing 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Delague V
Year: 2007
Journal: Am J Hum Genet
Title: Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H.
Volume: 81
Issue: 1
Pages: 1-16
Strain
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
Publication
First Author: Boubaker C
Year: 2013
Journal: Ann Hum Genet
Title: A novel mutation in FGD4/FRABIN causes Charcot Marie Tooth disease type 4H in patients from a consanguineous Tunisian family.
Volume: 77
Issue: 4
Pages: 336-43
Protein Domain
Type: Domain
Description: FGD4 (also known as FRABIN) is a member of the FGD family and is a small RhoGTPase Cdc42-guanine nucleotide exchange factor. It is associated with Charcot-Marie-Tooth neuropathy type 4 (CMT4), a group of progressive motor and sensory axonal and demyelinating neuropathies that are distinguished from other forms of CMT by autosomal recessive inheritance []. FGD4 has been shown to regulate Schwann cell endocytosis []. This entry represents the N-terminal PH domain of FGD4. FGDs have a RhoGEF (DH) domain, followed by an N-terminal PH domain, a FYVE domain and a C-terminal PH domain. All FGDs are guanine nucleotide exchange factors that activates the Rho GTPase Cdc42, an important regulator of membrane trafficking. The RhoGEF domain is responsible for GEF catalytic activity, while the N-terminal PH domain is involved in intracellular targeting of the DH domain []. PH domains have diverse functions, but in general are involved in targeting proteins to the appropriate cellular location or in the interaction with a binding partner []. They share little sequence conservation, but all have a common fold, which is electrostatically polarized. Less than 10% of PH domains bind phosphoinositide phosphates (PIPs) with high affinity and specificity []. PH domains are distinguished from other PIP-binding domains by their specific high-affinity binding to PIPs with two vicinal phosphate groups: PtdIns(3,4)P2, PtdIns(4,5)P2 or PtdIns(3,4,5)P3 which results in targeting some PH domain proteins to the plasma membrane []. A few display strong specificity in lipid binding. Any specificity is usually determined by loop regions or insertions in the N terminus of the domain, which are not conserved across all PH domains. PH domains are found in cellular signaling proteins such as serine/threonine kinase, tyrosine kinases, regulators of G-proteins, endocytotic GTPases, adaptors, as well as cytoskeletal associated molecules and in lipid associated enzymes [].
Publication
First Author: Oshima T
Year: 2011
Journal: Biol Pharm Bull
Title: Role of FGD1, a Cdc42 guanine nucleotide exchange factor, in epidermal growth factor-stimulated c-Jun NH2-terminal kinase activation and cell migration.
Volume: 34
Issue: 1
Pages: 54-60
Protein
Organism: Mus musculus/domesticus
Length: 766  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 754  
Fragment?: true
Publication
First Author: Lemmon MA
Year: 2004
Journal: Biochem Soc Trans
Title: Pleckstrin homology domains: not just for phosphoinositides.
Volume: 32
Issue: Pt 5
Pages: 707-11
Publication  
First Author: Cozier GE
Year: 2004
Journal: Curr Top Microbiol Immunol
Title: Membrane targeting by pleckstrin homology domains.
Volume: 282
Pages: 49-88
Publication
First Author: Scheffzek K
Year: 2012
Journal: FEBS Lett
Title: Pleckstrin homology (PH) like domains - versatile modules in protein-protein interaction platforms.
Volume: 586
Issue: 17
Pages: 2662-73