| Type |
Details |
Score |
| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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•
•
•
•
•
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| Publication |
| First Author: |
Kawai J |
| Year: |
2001 |
| Journal: |
Nature |
| Title: |
Functional annotation of a full-length mouse cDNA collection. |
| Volume: |
409 |
| Issue: |
6821 |
| Pages: |
685-90 |
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•
•
•
•
•
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| Publication |
| First Author: |
GemPharmatech |
| Year: |
2020 |
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| Title: |
GemPharmatech Website. |
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•
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| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
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•
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| Publication |
| First Author: |
UniProt-GOA |
| Year: |
2012 |
|
| Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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•
•
•
•
•
|
| Publication |
| First Author: |
Okazaki Y |
| Year: |
2002 |
| Journal: |
Nature |
| Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
| Volume: |
420 |
| Issue: |
6915 |
| Pages: |
563-73 |
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•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
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•
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•
•
•
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| Publication |
| First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
| Year: |
2010 |
|
| Title: |
Annotation inferences using phylogenetic trees |
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•
•
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•
•
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| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
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•
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•
•
•
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| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
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•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
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•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
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•
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•
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| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
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•
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•
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| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
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•
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•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
•
•
•
•
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| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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| DO Term |
|
•
•
•
•
•
|
| HT Experiment |
|
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
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•
•
•
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| Publication |
| First Author: |
Fimia GM |
| Year: |
2001 |
| Journal: |
Mol Cell Endocrinol |
| Title: |
Transcriptional cascades during spermatogenesis: pivotal role of CREM and ACT. |
| Volume: |
179 |
| Issue: |
1-2 |
| Pages: |
17-23 |
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•
•
•
•
•
|
| Publication |
| First Author: |
Fimia GM |
| Year: |
2000 |
| Journal: |
Mol Cell Biol |
| Title: |
A family of LIM-only transcriptional coactivators: tissue-specific expression and selective activation of CREB and CREM. |
| Volume: |
20 |
| Issue: |
22 |
| Pages: |
8613-22 |
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•
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| Protein Domain |
| Type: |
Domain |
| Description: |
This entry represents the second LIM domain of Four and a half LIM domains protein 5 (FHL5, also known as ACT), which belongs to the CREB/CREM family of transcription factors. FHL5 is highly expressed in male germ cells and is required for post-meiotic gene expression. It associates with CREM and confers a powerful transcriptional activation function []. Activation by CREB has known to occur upon phosphorylation at an essential regulatory site and the subsequent interaction with the ubiquitous coactivator CREB-binding protein (CBP). However, the activation by FHL5 is independent of phosphorylation and CBP association. It represents a new route for transcriptional activation by CREM and CREB [, ].LIM domains are 50-60 amino acids in size and share two characteristic zinc finger motifs. The two zinc fingers contain eight conserved residues, mostly cysteines and histidines, which coordinately bind to two zinc atoms. LIM domains function as adaptors or scaffolds to support the assembly of multimeric protein complexes [, , ]. |
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| Publication |
| First Author: |
Dawid IB |
| Year: |
1998 |
| Journal: |
Trends Genet |
| Title: |
LIM domains: multiple roles as adapters and functional modifiers in protein interactions. |
| Volume: |
14 |
| Issue: |
4 |
| Pages: |
156-62 |
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•
•
•
•
•
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| Publication |
| First Author: |
Zheng Q |
| Year: |
2007 |
| Journal: |
Biol Cell |
| Title: |
The diverse biofunctions of LIM domain proteins: determined by subcellular localization and protein-protein interaction. |
| Volume: |
99 |
| Issue: |
9 |
| Pages: |
489-502 |
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| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
284
 |
| Fragment?: |
false |
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•
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| Publication |
| First Author: |
Kadrmas JL |
| Year: |
2004 |
| Journal: |
Nat Rev Mol Cell Biol |
| Title: |
The LIM domain: from the cytoskeleton to the nucleus. |
| Volume: |
5 |
| Issue: |
11 |
| Pages: |
920-31 |
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