Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754623 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_18 |
|
Specimen Label: |
euxassay_000085_18 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_19 |
|
Specimen Label: |
euxassay_000085_19 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754623 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_20 |
|
Specimen Label: |
euxassay_000085_20 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754623 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_21 |
|
Specimen Label: |
euxassay_000085_21 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754623 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_22 |
|
Specimen Label: |
euxassay_000085_22 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Uniform |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_17 |
|
Specimen Label: |
euxassay_000085_17 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_18 |
|
Specimen Label: |
euxassay_000085_18 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_19 |
|
Specimen Label: |
euxassay_000085_19 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_20 |
|
Specimen Label: |
euxassay_000085_20 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Spotted |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_21 |
|
Specimen Label: |
euxassay_000085_21 |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_22 |
|
Specimen Label: |
euxassay_000085_22 |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679723 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_23 |
|
Specimen Label: |
euxassay_000085_23 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266436 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-05-04 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7266443 |
Age: |
postnatal day 42-56 |
|
Note: |
No overlap in with Gfap expression. |
Specimen Label: |
3G/I |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266436 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-05-04 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7266443 |
Age: |
postnatal day 42-56 |
|
Note: |
No overlap in with Gfap expression. |
Specimen Label: |
3J |
Detected: |
false |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7266436 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-05-04 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1757728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7266443 |
Age: |
postnatal day 42-56 |
|
Note: |
No overlap in with Gfap expression. |
Specimen Label: |
3K |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_18 |
|
Specimen Label: |
euxassay_000085_18 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:290503 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1679823 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4824862 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_000085_20 |
|
Specimen Label: |
euxassay_000085_20 |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mironova YA |
Year: |
2016 |
Journal: |
Elife |
Title: |
PI(3,5)P2 biosynthesis regulates oligodendrocyte differentiation by intrinsic and extrinsic mechanisms. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Porrello E |
Year: |
2014 |
Journal: |
J Exp Med |
Title: |
Jab1 regulates Schwann cell proliferation and axonal sorting through p27. |
Volume: |
211 |
Issue: |
1 |
Pages: |
29-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bridges D |
Year: |
2012 |
Journal: |
Mol Biol Cell |
Title: |
Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1. |
Volume: |
23 |
Issue: |
15 |
Pages: |
2955-62 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Publication |
First Author: |
Mammalian Functional Genomics Centre |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GO Central curators, GOA curators, Rhea curators |
Year: |
2020 |
|
Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
|
Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Allele |
Name: |
FIG4 phosphoinositide 5-phosphatase; pale tremor |
Allele Type: |
Spontaneous |
|
|
•
•
•
•
•
|
Genotype |
Symbol: |
Fig4/Fig4 |
Background: |
involves: 129P2/OlaHsd * C3H * C57BL/6 * CAST/Ei * SJL |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Fig4/Fig4 Tg(ACTB-Fig4*I41T)705Mm/? |
Background: |
involves: 129 * C3H * C57BL/6J * CAST/Ei * SJL |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Fig4/Fig4 |
Background: |
involves: 129P2/OlaHsd * C3H * SJL |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
FIG4 phosphoinositide 5-phosphatase; wild type |
Allele Type: |
Not Specified |
|
|
•
•
•
•
•
|
Genotype |
Symbol: |
Fig4/Fig4 Tg(Eno2-Fig4)#Mm/? |
Background: |
involves: 129P2/OlaHsd * C3H * C57BL/6 * CAST/Ei * SJL |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Fig4/Fig4 Tg(GFAP-Fig4)#Mm/? |
Background: |
involves: 129P2/OlaHsd * C3H * C57BL/6 * CAST/Ei * SJL |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
907
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, spontaneous mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
spontaneous mutation, mutant strain, congenic |
|
•
•
•
•
•
|
Allele |
Name: |
FIG4 phosphoinositide 5-phosphatase; targeted mutation 1, Velocigene |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Fig4/Fig4 |
Background: |
involves: 129 * C3H * C57BL/6J * CAST/Ei * SJL |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Fig4/Fig4 |
Background: |
B6.Cg-Fig4 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Fig4/Fig4 Tg(ACTB-Fig4*I41T)721Mm/? |
Background: |
involves: 129 * C3H * C57BL/6J * CAST/Ei * SJL |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
FIG4 phosphoinositide 5-phosphatase; gene trap D077F02, German Gene Trap Consortium |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
FIG4 phosphoinositide 5-phosphatase; gene trap OST390762, Lexicon Genetics |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
FIG4 phosphoinositide 5-phosphatase; targeted mutation 1, Mammalian Functional Genomics Centre |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
FIG4 phosphoinositide 5-phosphatase; targeted mutation 1.1. Miriam H Meisler |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
FIG4 phosphoinositide 5-phosphatase; endonuclease-mediated mutation 1, Institute of Molecular Genetics |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant stock, gene trap |
|
•
•
•
•
•
|
Allele |
Name: |
FIG4 phosphoinositide 5-phosphatase; gene trap IST13164B2, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
FIG4 phosphoinositide 5-phosphatase; gene trap IST13284A4, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Allele |
Name: |
FIG4 phosphoinositide 5-phosphatase; gene trap IST14906D5, Texas A&M Institute for Genomic Medicine |
Allele Type: |
Gene trapped |
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion, Miriam H Meisler |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Transgene |
Type: |
transgene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Fig4/Fig4 Tg(Syn1-cre)671Jxm/? |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 705, Miriam H Meisler |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 721, Miriam H Meisler |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion, Miriam H Meisler |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Michell RH |
Year: |
2009 |
Journal: |
EMBO J |
Title: |
A protein complex that regulates PtdIns(3,5)P2 levels. |
Volume: |
28 |
Issue: |
2 |
Pages: |
86-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Duex JE |
Year: |
2006 |
Journal: |
Eukaryot Cell |
Title: |
Phosphoinositide 5-phosphatase Fig 4p is required for both acute rise and subsequent fall in stress-induced phosphatidylinositol 3,5-bisphosphate levels. |
Volume: |
5 |
Issue: |
4 |
Pages: |
723-31 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of polyphosphoinositide phosphatases, including fungal Fig4 and its homologues from animals and plants. They contain a SAC (suppressor of actin) domain. Fig4 is part of the PtdIns(3,5)P2-synthesising complex of yeast at the vacuole membrane []and is involved in regulating both the acute rise and subsequent fall in PI3,5P(2) levels [].In Arabidopsis there are five Fig4 homologues, known as SAC1-5. They play an important role in vacuolar trafficking, vacuolar morphology and function in plants [].In humans, mutations of the FIG4 gene cause Charcot-Marie-Tooth disease 4J (CMT4J), a recessive demyelinating form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system []. |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Nováková P |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
SAC phosphoinositide phosphatases at the tonoplast mediate vacuolar function in Arabidopsis. |
Volume: |
111 |
Issue: |
7 |
Pages: |
2818-23 |
|
•
•
•
•
•
|
DO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Alghamdi TA |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Vac14 protein multimerization is a prerequisite step for Fab1 protein complex assembly and function. |
Volume: |
288 |
Issue: |
13 |
Pages: |
9363-72 |
|
•
•
•
•
•
|