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Search results 101 to 200 out of 3468 for Foxa2

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:6381640
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1604225
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7496052
Age: embryonic day 17.5
Image: 2B FOXA2 cKO Male E17.5
Specimen Label: 2B FOXA2 cKO Male E17.5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:6381640
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-07
Strength: Present
Sex: Female
Emaps: EMAPS:1604225
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7496052
Age: embryonic day 17.5
Image: 2B FOXA2 cKO Female E17.5
Specimen Label: 2B FOXA2 cKO Female E17.5
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:2449990
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1604620
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7496050
Age: embryonic day 12.5
Image: 2B FOXA2 cKO Male E12.5
Specimen Label: 2B FOXA2 cKO Male E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:2449990
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-07
Strength: Present
Sex: Female
Emaps: EMAPS:1604620
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7496050
Age: embryonic day 12.5
Image: 2B FOXA2 cKO Female E12.5
Specimen Label: 2B FOXA2 cKO Female E12.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:2449990
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-07
Strength: Present
Sex: Male
Emaps: EMAPS:1604625
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7496050
Age: embryonic day 17.5
Image: 2B FOXA2 cKO Male E17.5
Specimen Label: 2B FOXA2 cKO Male E17.5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:2449990
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-07
Strength: Present
Sex: Female
Emaps: EMAPS:1604625
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:7496050
Age: embryonic day 17.5
Image: 2B FOXA2 cKO Female E17.5
Specimen Label: 2B FOXA2 cKO Female E17.5
Detected: true
Specimen Num: 8
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Publication
17596284 | J:124122
First Author: Ferri AL
Year: 2007
Journal: Development
Title: Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner.
Volume: 134
Issue: 15
Pages: 2761-9
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Publication
37315133 | J:337001
First Author: Cheng C
Year: 2023
Journal: Sci Adv
Title: Yap controls notochord formation and neural tube patterning by integrating mechanotransduction with FoxA2 and Shh expression.
Volume: 9
Issue: 24
Pages: eadf6927
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Publication
24327960 | J:221305
First Author: Bochkis IM
Year: 2013
Journal: Mol Metab
Title: Bile acid-induced inflammatory signaling in mice lacking Foxa2 in the liver leads to activation of mTOR and age-onset obesity.
Volume: 2
Issue: 4
Pages: 447-56
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Publication
25249938 | J:309987
 
First Author: Domanskyi A
Year: 2014
Journal: Front Cell Neurosci
Title: Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance.
Volume: 8
Pages: 275
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Publication
18381283 | J:138581
First Author: Wolfrum C
Year: 2008
Journal: J Biol Chem
Title: Foxa2 activity increases plasma high density lipoprotein levels by regulating apolipoprotein M.
Volume: 283
Issue: 24
Pages: 16940-9
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Publication
16207754 | J:102951
First Author: Sawada A
Year: 2005
Journal: Development
Title: Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor.
Volume: 132
Issue: 21
Pages: 4719-29
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Publication
19234065 | J:146275
First Author: Burtscher I
Year: 2009
Journal: Development
Title: Foxa2 regulates polarity and epithelialization in the endoderm germ layer of the mouse embryo.
Volume: 136
Issue: 6
Pages: 1029-38
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Publication
24496614 | J:208435
First Author: Yi SH
Year: 2014
Journal: Development
Title: Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation.
Volume: 141
Issue: 4
Pages: 761-72
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Publication
19896480 | J:157265
First Author: McKnight KD
Year: 2010
Journal: Dev Biol
Title: Foxh1 and Foxa2 are not required for formation of the midgut and hindgut definitive endoderm.
Volume: 337
Issue: 2
Pages: 471-81
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Publication
15616563 | J:95662
First Author: Wolfrum C
Year: 2004
Journal: Nature
Title: Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes.
Volume: 432
Issue: 7020
Pages: 1027-32
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Publication
24401371 | J:221299
First Author: Mansour AA
Year: 2014
Journal: Development
Title: Nato3 plays an integral role in dorsoventral patterning of the spinal cord by segregating floor plate/p3 fates via Nkx2.2 suppression and Foxa2 maintenance.
Volume: 141
Issue: 3
Pages: 574-84
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Publication
19141476 | J:143476
First Author: Gao N
Year: 2008
Journal: Genes Dev
Title: Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.
Volume: 22
Issue: 24
Pages: 3435-48
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Publication
21093585 | J:170258
First Author: Mavromatakis YE
Year: 2011
Journal: Mech Dev
Title: Foxa1 and Foxa2 positively and negatively regulate Shh signalling to specify ventral midbrain progenitor identity.
Volume: 128
Issue: 1-2
Pages: 90-103
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Publication
37861292 | J:352884
   
First Author: Miura A
Year: 2023
Journal: Elife
Title: Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung.
Volume: 12
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Publication
31689237 | J:294562
First Author: Shen J
Year: 2019
Journal: Aging (Albany NY)
Title: Loss of FoxA2 accelerates neoplastic changes in the intrahepatic bile duct partly via the MAPK signaling pathway.
Volume: 11
Issue: 21
Pages: 9280-9294
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Publication
11914369 | J:77089
First Author: Weidenfeld J
Year: 2002
Journal: J Biol Chem
Title: The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium.
Volume: 277
Issue: 23
Pages: 21061-70
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Publication
31881038 | J:335455
First Author: Wei C
Year: 2019
Journal: PLoS One
Title: Molecular characterization of pulmonary defenses against bacterial invasion in allergic asthma: The role of Foxa2 in regulation of β-defensin 1.
Volume: 14
Issue: 12
Pages: e0226517
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Publication
24025729 | J:243482
First Author: Filant J
Year: 2014
Journal: FASEB J
Title: Integrated chromatin immunoprecipitation sequencing and microarray analysis identifies FOXA2 target genes in the glands of the mouse uterus.
Volume: 28
Issue: 1
Pages: 230-43
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Publication
26283356 | J:226713
First Author: Pristerà A
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice.
Volume: 112
Issue: 35
Pages: E4929-38
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Publication
23359409 | J:194054
First Author: Imuta Y
Year: 2013
Journal: Genesis
Title: Generation of knock-in mice that express nuclear enhanced green fluorescent protein and tamoxifen-inducible Cre recombinase in the notochord from Foxa2 and T loci.
Volume: 51
Issue: 3
Pages: 210-8
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Publication
17389379 | J:120359
First Author: Kimura-Yoshida C
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.
Volume: 104
Issue: 14
Pages: 5919-24
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Publication
21682884 | J:175564
 
First Author: Porter JL
Year: 2011
Journal: Respir Res
Title: Immunohistochemical detection and regulation of α5 nicotinic acetylcholine receptor (nAChR) subunits by FoxA2 during mouse lung organogenesis.
Volume: 12
Pages: 82
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Publication
20692247 | J:165741
First Author: Rojas A
Year: 2010
Journal: Dev Biol
Title: Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer.
Volume: 346
Issue: 2
Pages: 346-55
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Publication
23637192 | J:197145
First Author: Stott SR
Year: 2013
Journal: J Neurosci
Title: Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages.
Volume: 33
Issue: 18
Pages: 8022-34
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Publication
18336786 | J:134070
First Author: van der Sluis M
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells.
Volume: 369
Issue: 4
Pages: 1108-13
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Publication
22696295 | J:185583
First Author: Metzakopian E
Year: 2012
Journal: Development
Title: Genome-wide characterization of Foxa2 targets reveals upregulation of floor plate genes and repression of ventrolateral genes in midbrain dopaminergic progenitors.
Volume: 139
Issue: 14
Pages: 2625-34
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GXD Expression
GXD Expression
   
Probe: MGI:6173032
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190298
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Foxa2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6173032
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190298
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Foxa2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6173032
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190298
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Foxa2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6173032
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190298
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Foxa2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6173032
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190298
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Foxa2
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6173032
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190298
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Foxa2
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6173032
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190298
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Foxa2
Detected: true
Specimen Num: 7
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Publication
39251590 | J:354428
First Author: Arekatla G
Year: 2024
Journal: Nat Commun
Title: Identification of an embryonic differentiation stage marked by Sox1 and FoxA2 co-expression using combined cell tracking and high dimensional protein imaging.
Volume: 15
Issue: 1
Pages: 7860
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Publication
37944068 | J:345641
First Author: Zhang D
Year: 2024
Journal: Biol Reprod
Title: CK1α deficiency impairs mouse uterine adenogenesis by inducing epithelial cell apoptosis through GSK3β pathway and inhibiting Foxa2 expression through p53 pathway†.
Volume: 110
Issue: 2
Pages: 246-260
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Publication
32645357 | J:294224
First Author: Gredler ML
Year: 2020
Journal: Dev Biol
Title: Foxa1 and Foxa2 orchestrate development of the urethral tube and division of the embryonic cloaca through an autoregulatory loop with Shh.
Volume: 465
Issue: 1
Pages: 23-30
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Publication
35398294 | J:324296
 
First Author: Bell N
Year: 2022
Journal: Bone
Title: Overexpression of transcription factor FoxA2 in the developing skeleton causes an enlargement of the cartilage hypertrophic zone, but it does not trigger ectopic differentiation in immature chondrocytes.
Volume: 160
Pages: 116418
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Publication
23213408 | J:181536
First Author: Harrelson Z
Year: 2012
Journal: Biol Open
Title: Foxa2 mediates critical functions of prechordal plate in patterning and morphogenesis and is cell autonomously required for early ventral endoderm morphogenesis.
Volume: 1
Issue: 3
Pages: 173-81
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Publication
19607821 | J:152413
First Author: Lin W
Year: 2009
Journal: Dev Biol
Title: Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development.
Volume: 333
Issue: 2
Pages: 386-96
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Publication
20035737 | J:157957
First Author: Nakatani T
Year: 2010
Journal: Dev Biol
Title: Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon.
Volume: 339
Issue: 1
Pages: 101-13
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GXD Expression
GXD Expression
Probe: MGI:7510072
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7510116
Age: embryonic day 14.5
Image: S4B
Note: Low-level Foxa2 expression cells, lining the epithelial chords, coexpressed Muc1.
Specimen Label: S4B
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
Probe: MGI:6200641
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6200654
Age: embryonic day 10.5
Image: 6q
Note: There was a reduction of Foxa2 neuro-progenitors at the floorplate.
Specimen Label: 6q
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6200641
Assay Type: Immunohistochemistry
Annotation Date: 2018-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616517
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6200654
Age: embryonic day 10.5
Image: 6v
Note: There was a reduction of Foxa2 neuro-progenitors at the floorplate.
Specimen Label: 6v
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7510072
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7510116
Age: embryonic day 14.5
Image: S4E
Note: Most of the Foxa2 highly expressed cells were Ins1/2 negative (not beta-cells).
Specimen Label: S4E
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:7510072
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7510116
Age: embryonic day 14.5
Image: S4A
Note: High-level Foxa2 expression cells did not express Sox9. Coexpressed with Sox9 in low-level Foxa2 expression cells.
Specimen Label: S4A
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:1338477
Assay Type: Immunohistochemistry
Annotation Date: 2019-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614015
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:6343551
Age: embryonic day 9.25
Image: S1 E9.25
Note: Compared to an adjacent section, Foxa2 expression overlaps with Gli2 at E9.25.
Specimen Label: S1 E9.25
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
Probe: MGI:7510072
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7510116
Age: embryonic day 14.5
Image: S4F
Note: Almost complete overlap between Foxa2 highly expressed cells and Chga expression, showing their likely specification toward an endocrine fate.
Specimen Label: S4F
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:1338477
Assay Type: Immunohistochemistry
Annotation Date: 2019-08-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697420
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:6343551
Age: embryonic day 12.5
Image: S1 E12.5
Note: Compared to an adjacent section, the dorsal limit of Foxa2 expression abuts the ventral limit of Gli2 expression at E12.5.
Specimen Label: S1 E12.5
Detected: true
Specimen Num: 19
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GXD Expression
GXD Expression
Probe: MGI:7510072
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7510116
Age: embryonic day 14.5
Image: S4D
Note: Almost complete overlap between Foxa2 and Pdx1 expression. Most of the Pdx1 highly expressed cells did not display the highest levels of Foxa2.
Specimen Label: S4D
Detected: true
Specimen Num: 9
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Publication
18061569 | J:130469
First Author: Yamanaka Y
Year: 2007
Journal: Dev Cell
Title: Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms.
Volume: 13
Issue: 6
Pages: 884-96
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Publication
15231714 | J:91405
First Author: Abdelkhalek HB
Year: 2004
Journal: Genes Dev
Title: The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation.
Volume: 18
Issue: 14
Pages: 1725-36
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Publication
9078367 | J:176642
First Author: Sasaki H
Year: 1996
Journal: Genes Cells
Title: Enhancer analysis of the mouse HNF-3 beta gene: regulatory elements for node/notochord and floor plate are independent and consist of multiple sub-elements.
Volume: 1
Issue: 1
Pages: 59-72
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Publication
11846474 | J:75055
First Author: Hallonet M
Year: 2002
Journal: Dev Biol
Title: Maintenance of the specification of the anterior definitive endoderm and forebrain depends on the axial mesendoderm: a study using HNF3beta/Foxa2 conditional mutants.
Volume: 243
Issue: 1
Pages: 20-33
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GXD Expression
GXD Expression
Probe: MGI:7510072
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3564523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:7510116
Age: embryonic day 15.5
Image: 5A/B/C
Note: Expressed at lower levels in the cells lining the lumen of the epithelial chords, while high level cells were detected within or adjacent to the epithelial chords. There was a statistically significant correlation between Neurog3 and Foxa2 expression levels (see Fig 5D and 5E).
Specimen Label: 5A/B/C
Detected: true
Specimen Num: 1
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HT Experiment
E-MEXP-3428 | Gene expression profiles of Foxa1 and Foxa2 single and double mutants in embryonic mouse liver
 
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
36516856 | J:332655
First Author: Delás MJ
Year: 2023
Journal: Dev Cell
Title: Developmental cell fate choice in neural tube progenitors employs two distinct cis-regulatory strategies.
Volume: 58
Issue: 1
Pages: 3-17.e8
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Publication
12865419 | J:84920
First Author: Wolfrum C
Year: 2003
Journal: J Clin Invest
Title: Role of Foxa-2 in adipocyte metabolism and differentiation.
Volume: 112
Issue: 3
Pages: 345-56
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Publication
8530406 | J:30127
First Author: Kaestner KH
Year: 1995
Journal: J Biol Chem
Title: The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.
Volume: 270
Issue: 50
Pages: 30029-35
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Publication
15533813 | J:93513
First Author: Plouhinec JL
Year: 2004
Journal: Gene Expr Patterns
Title: Identification of the mammalian Not gene via a phylogenomic approach.
Volume: 5
Issue: 1
Pages: 11-22
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Publication
9598342 | J:47841
 
First Author: Varlet I
Year: 1997
Journal: Cold Spring Harb Symp Quant Biol
Title: Nodal signaling and axis formation in the mouse.
Volume: 62
Pages: 105-13
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Publication
11291865 | J:74124
First Author: Kinder SJ
Year: 2001
Journal: Int J Dev Biol
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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