Type |
Details |
Score |
Publication |
First Author: |
Zhang H |
Year: |
2012 |
Journal: |
Endocrinology |
Title: |
Novel genes of visceral adiposity: identification of mouse and human mesenteric estrogen-dependent adipose (MEDA)-4 gene and its adipogenic function. |
Volume: |
153 |
Issue: |
6 |
Pages: |
2665-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen X |
Year: |
2011 |
Journal: |
Oncogene |
Title: |
Anti-proliferative and pro-apoptotic actions of a novel human and mouse ovarian tumor-associated gene OTAG-12: downregulation, alternative splicing and drug sensitization. |
Volume: |
30 |
Issue: |
25 |
Pages: |
2874-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Grover A |
Year: |
2004 |
Journal: |
Biol Reprod |
Title: |
Structural and functional modifications of sertoli cells in the testis of adult follicle-stimulating hormone receptor knockout mice. |
Volume: |
71 |
Issue: |
1 |
Pages: |
117-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar TR |
Year: |
1997 |
Journal: |
Nat Genet |
Title: |
Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility. |
Volume: |
15 |
Issue: |
2 |
Pages: |
201-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang H |
Year: |
2011 |
Journal: |
Diabetologia |
Title: |
Novel hormone-regulated genes in visceral adipose tissue: cloning and identification of proinflammatory cytokine-like mouse and human MEDA-7: implications for obesity, insulin resistance and the metabolic syndrome. |
Volume: |
54 |
Issue: |
9 |
Pages: |
2368-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abel MH |
Year: |
2000 |
Journal: |
Endocrinology |
Title: |
The effect of a null mutation in the follicle-stimulating hormone receptor gene on mouse reproduction. |
Volume: |
141 |
Issue: |
5 |
Pages: |
1795-803 |
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•
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•
•
•
|
Publication |
First Author: |
O'Shaughnessy PJ |
Year: |
1994 |
Journal: |
Mol Cell Endocrinol |
Title: |
Follicle-stimulating hormone receptor mRNA in the mouse ovary during post-natal development in the normal mouse and in the adult hypogonadal (hpg) mouse: structure of alternate transcripts. |
Volume: |
101 |
Issue: |
1-2 |
Pages: |
197-201 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johnston H |
Year: |
2004 |
Journal: |
Endocrinology |
Title: |
Regulation of Sertoli cell number and activity by follicle-stimulating hormone and androgen during postnatal development in the mouse. |
Volume: |
145 |
Issue: |
1 |
Pages: |
318-29 |
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•
•
•
•
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|
Publication |
First Author: |
Zhu LL |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Blocking antibody to the β-subunit of FSH prevents bone loss by inhibiting bone resorption and stimulating bone synthesis. |
Volume: |
109 |
Issue: |
36 |
Pages: |
14574-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao J |
Year: |
2007 |
Journal: |
Endocrinology |
Title: |
Altered ovarian function affects skeletal homeostasis independent of the action of follicle-stimulating hormone. |
Volume: |
148 |
Issue: |
6 |
Pages: |
2613-21 |
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•
•
•
•
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Publication |
First Author: |
Huhtaniemi IT |
Year: |
1992 |
Journal: |
Mol Cell Endocrinol |
Title: |
The murine luteinizing hormone and follicle-stimulating hormone receptor genes: transcription initiation sites, putative promoter sequences and promoter activity. |
Volume: |
88 |
Issue: |
1-3 |
Pages: |
55-66 |
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•
•
•
•
|
Publication |
First Author: |
Chen X |
Year: |
2006 |
Journal: |
Carcinogenesis |
Title: |
Aberrant expression of PDGF ligands and receptors in the tumor prone ovary of follitropin receptor knockout (FORKO) mouse. |
Volume: |
27 |
Issue: |
5 |
Pages: |
903-15 |
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•
•
•
•
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Publication |
First Author: |
Véliz LP |
Year: |
2008 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Functional role of gap junctions in cytokine-induced leukocyte adhesion to endothelium in vivo. |
Volume: |
295 |
Issue: |
3 |
Pages: |
H1056-H1066 |
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•
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Publication |
First Author: |
Ebrahimian T |
Year: |
2008 |
Journal: |
Am J Physiol Heart Circ Physiol |
Title: |
Cardiac hypertrophy is associated with altered thioredoxin and ASK-1 signaling in a mouse model of menopause. |
Volume: |
295 |
Issue: |
4 |
Pages: |
H1481-8 |
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•
•
•
•
•
|
Publication |
First Author: |
Kim KH |
Year: |
2008 |
Journal: |
Biol Reprod |
Title: |
SEBOX is essential for early embryogenesis at the two-cell stage in the mouse. |
Volume: |
79 |
Issue: |
6 |
Pages: |
1192-201 |
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•
•
•
•
•
|
Publication |
First Author: |
Danilovich N |
Year: |
2005 |
Journal: |
Endocrine |
Title: |
Targeting gonadotropin receptor genes: reproductive biology, aging, and related health implications. |
Volume: |
26 |
Issue: |
3 |
Pages: |
219-26 |
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•
•
•
•
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Publication |
First Author: |
O'Shaughnessy PJ |
Year: |
1997 |
Journal: |
Biol Reprod |
Title: |
Regulation of luteinizing hormone-receptor and follicle-stimulating hormone-receptor messenger ribonucleic acid levels during development in the neonatal mouse ovary. |
Volume: |
57 |
Issue: |
3 |
Pages: |
602-8 |
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•
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Publication |
First Author: |
Abel MH |
Year: |
2003 |
Journal: |
Reproduction |
Title: |
Age-related uterine and ovarian hypertrophy in FSH receptor knockout and FSHbeta subunit knockout mice. |
Volume: |
125 |
Issue: |
2 |
Pages: |
165-73 |
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•
•
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Publication |
First Author: |
Sun L |
Year: |
2006 |
Journal: |
Cell |
Title: |
FSH directly regulates bone mass. |
Volume: |
125 |
Issue: |
2 |
Pages: |
247-60 |
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•
•
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Publication |
First Author: |
Danilovich N |
Year: |
2006 |
Journal: |
Exp Gerontol |
Title: |
Recent female mouse models displaying advanced reproductive aging. |
Volume: |
41 |
Issue: |
2 |
Pages: |
117-22 |
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•
•
•
•
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Publication |
First Author: |
Danilovich N |
Year: |
2003 |
Journal: |
Exp Neurol |
Title: |
Age-related neurodegenerative changes in the central nervous system of estrogen-deficient follitropin receptor knockout mice. |
Volume: |
183 |
Issue: |
2 |
Pages: |
559-72 |
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•
•
•
•
•
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Publication |
First Author: |
Danilovich N |
Year: |
2003 |
Journal: |
Neuroreport |
Title: |
The menopausal mouse: a new neural paradigm of a distressing human condition. |
Volume: |
14 |
Issue: |
12 |
Pages: |
1617-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abel MH |
Year: |
2008 |
Journal: |
Endocrinology |
Title: |
Spermatogenesis and sertoli cell activity in mice lacking sertoli cell receptors for follicle-stimulating hormone and androgen. |
Volume: |
149 |
Issue: |
7 |
Pages: |
3279-85 |
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•
•
•
•
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Publication |
First Author: |
Patsoula E |
Year: |
2001 |
Journal: |
Reproduction |
Title: |
Expression of mRNA for the LH and FSH receptors in mouse oocytes and preimplantation embryos. |
Volume: |
121 |
Issue: |
3 |
Pages: |
455-61 |
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•
•
•
•
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Publication |
First Author: |
Xing Y |
Year: |
2006 |
Journal: |
Reproduction |
Title: |
Murine homologues of the Drosophila gustavus gene are expressed in ovarian granulosa cells. |
Volume: |
131 |
Issue: |
5 |
Pages: |
905-15 |
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•
•
•
•
•
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Publication |
First Author: |
Laissue P |
Year: |
2015 |
Journal: |
Mol Cell Endocrinol |
Title: |
Aetiological coding sequence variants in non-syndromic premature ovarian failure: From genetic linkage analysis to next generation sequencing. |
Volume: |
411 |
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Pages: |
243-57 |
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Publication |
First Author: |
Hirst RC |
Year: |
2004 |
Journal: |
Reproduction |
Title: |
Influence of mutations affecting gonadotropin production or responsiveness on expression of inhibin subunit mRNA and protein in the mouse ovary. |
Volume: |
128 |
Issue: |
1 |
Pages: |
43-52 |
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Publication |
First Author: |
Aravindakshan J |
Year: |
2006 |
Journal: |
Neoplasia |
Title: |
Differential expression of claudin family proteins in mouse ovarian serous papillary epithelial adenoma in aging FSH receptor-deficient mutants. |
Volume: |
8 |
Issue: |
12 |
Pages: |
984-94 |
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Publication |
First Author: |
Hsieh TB |
Year: |
2024 |
Journal: |
J Ovarian Res |
Title: |
Loss of Calponin 2 causes premature ovarian insufficiency in mice. |
Volume: |
17 |
Issue: |
1 |
Pages: |
37 |
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Publication |
First Author: |
Tong GQ |
Year: |
2007 |
Journal: |
J Zhejiang Univ Sci B |
Title: |
Cumulus-specific genes are transcriptionally silent following somatic cell nuclear transfer in a mouse model. |
Volume: |
8 |
Issue: |
8 |
Pages: |
533-9 |
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Publication |
First Author: |
Upton DH |
Year: |
2015 |
Journal: |
Horm Cancer |
Title: |
Granulosa Cell-Specific Brca1 Loss Alone or Combined with Trp53 Haploinsufficiency and Transgenic FSH Expression Fails to Induce Ovarian Tumors. |
Volume: |
6 |
Issue: |
4 |
Pages: |
142-52 |
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Publication |
First Author: |
Umehara T |
Year: |
2016 |
Journal: |
Endocrinology |
Title: |
Neuregulin 1 Regulates Proliferation of Leydig Cells to Support Spermatogenesis and Sexual Behavior in Adult Mice. |
Volume: |
157 |
Issue: |
12 |
Pages: |
4899-4913 |
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First Author: |
Choi Y |
Year: |
2006 |
Journal: |
Cell Mol Life Sci |
Title: |
Genetics of early mammalian folliculogenesis. |
Volume: |
63 |
Issue: |
5 |
Pages: |
579-90 |
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First Author: |
Balla A |
Year: |
2003 |
Journal: |
Biol Reprod |
Title: |
Dynamics of ovarian development in the FORKO immature mouse: structural and functional implications for ovarian reserve. |
Volume: |
69 |
Issue: |
4 |
Pages: |
1281-93 |
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Publication |
First Author: |
Song C |
Year: |
2024 |
Journal: |
Sci China Life Sci |
Title: |
Deleterious variants in RNF111 impair female fertility and induce premature ovarian insufficiency in humans and mice. |
Volume: |
67 |
Issue: |
7 |
Pages: |
1325-1337 |
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First Author: |
Urano A |
Year: |
2005 |
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Mol Cell Biol |
Title: |
Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia. |
Volume: |
25 |
Issue: |
15 |
Pages: |
6834-45 |
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Publication |
First Author: |
Hahn KL |
Year: |
2005 |
Journal: |
Development |
Title: |
Lunatic fringe null female mice are infertile due to defects in meiotic maturation. |
Volume: |
132 |
Issue: |
4 |
Pages: |
817-28 |
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First Author: |
Luo X |
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2024 |
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BMC Biol |
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Casein kinase 1α mediates estradiol secretion via CYP19A1 expression in mouse ovarian granulosa cells. |
Volume: |
22 |
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1 |
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176 |
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Wang PJ |
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Nat Genet |
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An abundance of X-linked genes expressed in spermatogonia. |
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27 |
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2017 |
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Hum Mol Genet |
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Age-dependent effects of Armc5 haploinsufficiency on adrenocortical function. |
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Rotgers E |
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2021 |
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FASEB J |
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Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility, and metabolic homeostasis in female mice. |
Volume: |
35 |
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e21770 |
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Heinrich A |
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2020 |
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Cell Rep |
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Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and Spermatogenesis. |
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First Author: |
Wen Y |
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2021 |
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Theranostics |
Title: |
hnRNPU in Sertoli cells cooperates with WT1 and is essential for testicular development by modulating transcriptional factors Sox8/9. |
Volume: |
11 |
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Exp Cell Res |
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A global genomic transcriptional code associated with CNS-expressed genes. |
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312 |
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First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
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First Author: |
Velocigene |
Year: |
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Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
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GUDMAP Consortium |
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GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
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Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
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Database Release |
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The Gene Ontology Consortium |
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BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
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Mouse Genome Informatics Scientific Curators |
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Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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Adams DJ |
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UniProt-GOA |
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Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
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Mouse Genome Database and National Center for Biotechnology Information |
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Allen Institute for Brain Science |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
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Journal: |
Database Download |
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Mouse Genome Informatics Group |
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Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Obtaining and loading genome assembly coordinates from NCBI annotations |
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Database Download |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
692
 |
Fragment?: |
false |
|
•
•
•
•
•
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Publication |
First Author: |
Teino I |
Year: |
2012 |
Journal: |
Biol Reprod |
Title: |
The aryl hydrocarbon receptor regulates mouse Fshr promoter activity through an e-box binding site. |
Volume: |
86 |
Issue: |
3 |
Pages: |
77 |
|
•
•
•
•
•
|
Allele |
Name: |
follicle stimulating hormone receptor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, endonuclease-mediated mutation |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion, Ilpo Huhtaniemi |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(AMH-Fshr*D580Y)#Hht/? |
Background: |
involves: FVB/N |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE77479 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Publication |
First Author: |
Allan CM |
Year: |
2009 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Transgenic mutant D567G but not wild-type human FSH receptor overexpression provides FSH-independent and promiscuous glycoprotein hormone Sertoli cell signaling. |
Volume: |
296 |
Issue: |
5 |
Pages: |
E1022-8 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Charles M Allan |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion, Ilpo Huhtaniemi |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 14, Ilpo Huhtaniemi |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(AMH-Fshr*D580H)14Hht/? |
Background: |
involves: FVB/N |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(AMH-Fshr*D580H)#Hht/? |
Background: |
involves: FVB/N |
Zygosity: |
ot |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Allan CM |
Year: |
2006 |
Journal: |
Biol Reprod |
Title: |
Maintenance of spermatogenesis by the activated human (Asp567Gly) FSH receptor during testicular regression due to hormonal withdrawal. |
Volume: |
74 |
Issue: |
5 |
Pages: |
938-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Allan CM |
Year: |
2004 |
Journal: |
Endocrinology |
Title: |
Complete Sertoli cell proliferation induced by follicle-stimulating hormone (FSH) independently of luteinizing hormone activity: evidence from genetic models of isolated FSH action. |
Volume: |
145 |
Issue: |
4 |
Pages: |
1587-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gromoll J |
Year: |
1996 |
Journal: |
Genomics |
Title: |
The structure and organization of the human follicle-stimulating hormone receptor (FSHR) gene. |
Volume: |
35 |
Issue: |
2 |
Pages: |
308-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kerr B |
Year: |
2009 |
Journal: |
Reproduction |
Title: |
NTRK1 and NTRK2 receptors facilitate follicle assembly and early follicular development in the mouse ovary. |
Volume: |
138 |
Issue: |
1 |
Pages: |
131-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andreu-Vieyra C |
Year: |
2008 |
Journal: |
Mol Endocrinol |
Title: |
Conditional deletion of the retinoblastoma (Rb) gene in ovarian granulosa cells leads to premature ovarian failure. |
Volume: |
22 |
Issue: |
9 |
Pages: |
2141-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barnett KR |
Year: |
2007 |
Journal: |
Toxicol Appl Pharmacol |
Title: |
The aryl hydrocarbon receptor is required for normal gonadotropin responsiveness in the mouse ovary. |
Volume: |
223 |
Issue: |
1 |
Pages: |
66-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou J |
Year: |
1997 |
Journal: |
Mol Endocrinol |
Title: |
Insulin-like growth factor I regulates gonadotropin responsiveness in the murine ovary. |
Volume: |
11 |
Issue: |
13 |
Pages: |
1924-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gong X |
Year: |
2009 |
Journal: |
Biol Reprod |
Title: |
Smad3 is required for normal follicular follicle-stimulating hormone responsiveness in the mouse. |
Volume: |
81 |
Issue: |
4 |
Pages: |
730-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sargent KM |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
Loss of vascular endothelial growth factor A (VEGFA) isoforms in granulosa cells using pDmrt-1-Cre or Amhr2-Cre reduces fertility by arresting follicular development and by reducing litter size in female mice. |
Volume: |
10 |
Issue: |
2 |
Pages: |
e0116332 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hazra R |
Year: |
2014 |
Journal: |
Endocrinology |
Title: |
In vivo actions of the Sertoli cell glucocorticoid receptor. |
Volume: |
155 |
Issue: |
3 |
Pages: |
1120-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huhtaniemi I |
Year: |
2006 |
Journal: |
Mol Cell Endocrinol |
Title: |
Mutations along the pituitary-gonadal axis affecting sexual maturation: novel information from transgenic and knockout mice. |
Volume: |
254-255 |
|
Pages: |
84-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ma Y |
Year: |
2017 |
Journal: |
Endocrinology |
Title: |
Androgen Receptor in the Ovary Theca Cells Plays a Critical Role in Androgen-Induced Reproductive Dysfunction. |
Volume: |
158 |
Issue: |
1 |
Pages: |
98-108 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bennett J |
Year: |
2012 |
Journal: |
Endocrinology |
Title: |
Loss of GATA-6 and GATA-4 in granulosa cells blocks folliculogenesis, ovulation, and follicle stimulating hormone receptor expression leading to female infertility. |
Volume: |
153 |
Issue: |
5 |
Pages: |
2474-85 |
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•
•
•
•
•
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