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Search results 101 to 189 out of 189 for Fxr2

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Type Details Score
Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Fxr2<tm1Cgr> | MGI:2388128
Name: FMR1 autosomal homolog 2; targeted mutation 1, Ben Oostra
Allele Type: Targeted
Attribute String: Null/knockout
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GXD Expression
GXD Expression
   
Probe: MGI:7464388
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464719
Age: postnatal month 2
Image: 1
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7464388
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464719
Age: postnatal month 2
Image: 1
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:7464388
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464719
Age: postnatal month 2
Image: 1
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7464388
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464719
Age: postnatal month 2
Image: 1
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:7464388
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464724
Age: postnatal month 2
Image: 1
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7464388
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464724
Age: postnatal month 2
Image: 1
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:7464388
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464724
Age: postnatal month 2
Image: 1
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7464388
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464724
Age: postnatal month 2
Image: 1
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:7464388
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464725
Age: postnatal month 2
Image: 1
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7464388
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464725
Age: postnatal month 2
Image: 1
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:7464388
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464725
Age: postnatal month 2
Image: 1
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7464388
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464725
Age: postnatal month 2
Image: 1
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:7464393
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464731
Age: postnatal month 2
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7464393
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464727
Age: postnatal month 2
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7464393
Assay Type: Northern blot
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464730
Age: postnatal month 2
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7464385
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464751
Age: postnatal month 2
Image: 2
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7464387
Assay Type: RT-PCR
Annotation Date: 2023-04-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7464753
Age: postnatal month 2
Image: 2
Specimen Label: fxr2 KO
Detected: true
Specimen Num: 3
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Publication
7489725 | J:59611
First Author: Zhang Y
Year: 1995
Journal: EMBO J
Title: The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2.
Volume: 14
Issue: 21
Pages: 5358-66
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Publication
10556305 | J:58813
First Author: Bardoni B
Year: 1999
Journal: Hum Mol Genet
Title: A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein.
Volume: 8
Issue: 13
Pages: 2557-66
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Publication
15128702 | J:91191
First Author: Mientjes EJ
Year: 2004
Journal: Hum Mol Genet
Title: Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo.
Volume: 13
Issue: 13
Pages: 1291-302
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Publication
30770808 | J:276784
First Author: Estañ MC
Year: 2019
Journal: Nat Commun
Title: Recessive mutations in muscle-specific isoforms of FXR1 cause congenital multi-minicore myopathy.
Volume: 10
Issue: 1
Pages: 797
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Protein
A0A0G2JGH0
Organism: Mus musculus/domesticus
Length: 54  
Fragment?: false
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Publication
30115809 | -
First Author: Greenblatt EJ
Year: 2018
Journal: Science
Title: Fragile X mental retardation 1 gene enhances the translation of large autism-related proteins.
Volume: 361
Issue: 6403
Pages: 709-712
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Publication
1710175 | -
First Author: Verkerk AJ
Year: 1991
Journal: Cell
Title: Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome.
Volume: 65
Issue: 5
Pages: 905-14
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Publication
7781595 | -
First Author: Siomi MC
Year: 1995
Journal: EMBO J
Title: FXR1, an autosomal homolog of the fragile X mental retardation gene.
Volume: 14
Issue: 11
Pages: 2401-8
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Publication
19669947 | -
First Author: Li X
Year: 2009
Journal: Neuromolecular Med
Title: Macro role(s) of microRNAs in fragile X syndrome?
Volume: 11
Issue: 3
Pages: 200-7
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Publication
18957214 | -
First Author: Bassell GJ
Year: 2008
Journal: Neuron
Title: Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function.
Volume: 60
Issue: 2
Pages: 201-14
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Protein Domain
IPR040148 | FMR1
Type: Family
Description: Fragile X messenger ribonucleoprotein 1 (FMRP/FMR1), and its paralogues, FXR1 and FXR2 (RNA-binding protein FXR1 and 2, respectively), comprise a family of RNA-binding proteins [].FMR1 protein is a multifunctional polyribosome-associated protein that plays a central role in neuronal development and synaptic plasticity. It regulates alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of a subset of mRNAs [, , ]. FMR1 is thought to bind target mRNA in the nucleus to form a ribonucleoprotein complex which is transported to dendrites and spines []. It is also required for ovary development and function []. FMR1 has also been shown to interact with components of the miRNA pathway []. A large expansion of the CGG trinucleotide repeat in the 5'-untranslated region of the FMR1 gene causes Fragile X syndrome (FXS), an inherited developmental disorder that causes a broad range of intellectual and physical challenges [].FXR1 and FXR2 interact with FMR1 and seem to have a related role; therefore they are likely to play important roles in the function of FMR1 and in the pathogenesis of the FXS syndrome [, ]. FXR1 is highly expressed in vertebrates muscle cells and is required for proper development of this tissue [, ].
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Protein
Q925S6
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: true
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Protein
Q925S7
Organism: Mus musculus/domesticus
Length: 35  
Fragment?: true
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Protein
A0A0G2JGL6
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: true
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Publication
21072162 | -
First Author: Adams-Cioaba MA
Year: 2010
Journal: PLoS One
Title: Structural studies of the tandem Tudor domains of fragile X mental retardation related proteins FXR1 and FXR2.
Volume: 5
Issue: 11
Pages: e13559
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Publication
10912798 | J:63269
First Author: Bakker CE
Year: 2000
Journal: Exp Cell Res
Title: Immunocytochemical and biochemical characterization of FMRP, FXR1P, and FXR2P in the mouse.
Volume: 258
Issue: 1
Pages: 162-70
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Publication
16886907 | J:116528
First Author: Mahishi L
Year: 2006
Journal: Biochem J
Title: NF-Y, AP2, Nrf1 and Sp1 regulate the fragile X-related gene 2 (FXR2).
Volume: 400
Issue: 2
Pages: 327-35
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Publication
28960184 | -
 
First Author: Hagerman RJ
Year: 2017
Journal: Nat Rev Dis Primers
Title: Fragile X syndrome.
Volume: 3
Pages: 17065
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Publication
29713264 | -
 
First Author: Drozd M
Year: 2018
Journal: Front Mol Neurosci
Title: Modeling Fragile X Syndrome in Drosophila.
Volume: 11
Pages: 124
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Publication
25464849 | J:232981
First Author: Kenny PJ
Year: 2014
Journal: Cell Rep
Title: MOV10 and FMRP regulate AGO2 association with microRNA recognition elements.
Volume: 9
Issue: 5
Pages: 1729-41
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Protein
Q8C7U4
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: true
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Protein
Q8BPK8
Organism: Mus musculus/domesticus
Length: 357  
Fragment?: true
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Protein
Q8BPN5
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: true
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Protein
Q61584
Organism: Mus musculus/domesticus
Length: 677  
Fragment?: false
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Protein
Q9WVR4
Organism: Mus musculus/domesticus
Length: 673  
Fragment?: false
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Protein
P35922
Organism: Mus musculus/domesticus
Length: 614  
Fragment?: false
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Protein
A0A0G2JEP0
Organism: Mus musculus/domesticus
Length: 568  
Fragment?: false
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Protein
Q6P5B5
Organism: Mus musculus/domesticus
Length: 674  
Fragment?: false
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Protein
Q6AXB7
Organism: Mus musculus/domesticus
Length: 614  
Fragment?: false
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Protein
E9QAS8
Organism: Mus musculus/domesticus
Length: 631  
Fragment?: false
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Protein
E9QAT0
Organism: Mus musculus/domesticus
Length: 589  
Fragment?: false
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Protein
E9QAS9
Organism: Mus musculus/domesticus
Length: 585  
Fragment?: false
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Protein
Q3TA75
Organism: Mus musculus/domesticus
Length: 655  
Fragment?: true
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Protein
A0A0H2UH27
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
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Protein
E9QNF5
Organism: Mus musculus/domesticus
Length: 593  
Fragment?: false
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Protein
D3Z6U8
Organism: Mus musculus/domesticus
Length: 591  
Fragment?: false
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Protein
Q547R0
Organism: Mus musculus/domesticus
Length: 589  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom