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Search results 101 to 200 out of 264 for Gab1

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Hits by Strain

Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:7413179
Assay Type: RT-PCR
Annotation Date: 2022-12-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3669920
Stage: TS20
Assay Id: MGI:7413182
Age: embryonic day 12.5
Image: S2
Specimen Label: PGCs +RT
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:3759267
Assay Type: RNA in situ
Annotation Date: 2007-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3516422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3759269
Age: embryonic day 13.75
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1004568
Assay Type: RNA in situ
Annotation Date: 2018-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6267461
Age: embryonic day 14.5
Specimen Label: Table S1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1004568
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540365
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4A Cochlea
Specimen Label: 4A Cochlea
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Apical
Specimen Label: 4D Apical
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
Probe: MGI:7610066
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610081
Age: postnatal adult
Image: 5 Spiral ganglion
Note: Expression co-colocalized with Mettl13 and Nefh expression in neural call bodies of spiral ganglion.
Specimen Label: 5 Spiral ganglion
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:3759267
Assay Type: RNA in situ
Annotation Date: 2007-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3759269
Age: embryonic day 13.75
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:3759267
Assay Type: RNA in situ
Annotation Date: 2007-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689622
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3759269
Age: embryonic day 13.75
Image: 3C
Note: Expression is in the basal diencephalon.
Specimen Label: 3C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3543827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Apical
Specimen Label: 4D Apical
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3543827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Middle
Specimen Label: 4D Middle
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3543827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Basal
Specimen Label: 4D Basal
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3549627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4A Cochlea
Specimen Label: 4A Cochlea
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3549627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Apical
Specimen Label: 4D Apical
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3549627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Middle
Specimen Label: 4D Middle
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3549627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Basal
Specimen Label: 4D Basal
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3533227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Apical
Specimen Label: 4D Apical
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3533227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Middle
Specimen Label: 4D Middle
Detected: true
Specimen Num: 5
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•
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3533227
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Basal
Specimen Label: 4D Basal
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
Probe: MGI:7610066
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610081
Age: postnatal adult
Image: 5 Innervation
Note: Expression co-colocalized with Mettl13 and Nefh expression in nerve fibers innervating inner hair cells and outer hair cells in cochlear duct.
Specimen Label: 5 Innervation
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4A Cochlea
Specimen Label: 4A Cochlea
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Apical
Specimen Label: 4D Apical
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Middle
Specimen Label: 4D Middle
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4D Basal
Specimen Label: 4D Basal
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1906127
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4A Cochlea
Note: No detectable expression in inner or outer hair cells.
Specimen Label: 4A Cochlea
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1906127
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4A Cochlea
Note: No detectable expression in inner or outer hair cells.
Specimen Label: 4A Cochlea
Detected: false
Specimen Num: 1
•
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•
GXD Expression
GXD Expression
 
Probe: MGI:7610066
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7610081
Age: postnatal adult
Image: 5 Cochlear duct
Specimen Label: 5 Cochlear duct
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1004568
Assay Type: RNA in situ
Annotation Date: 2018-12-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6267461
Age: embryonic day 14.5
Specimen Label: Table S1
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:1004568
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540365
Age: embryonic day 14.5
Note: Ventricular zone expression was greater than in the cortical plate.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729527
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4C Utricle
Note: Expression in sensory epithelium. Little or no expression in nonsensory epitheium.
Specimen Label: 4C Utricle
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7610075
Age: postnatal day 0
Image: 4B Ampulla
Note: Expression in sensory epithelium. Expression in transition cells. Little or no expression in nonsensory epitheium
Specimen Label: 4B Ampulla
Detected: true
Specimen Num: 2
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Publication
32358519 | J:287305
First Author: Inoue K
Year: 2020
Journal: Nat Commun
Title: Loss of H3K27me3 imprinting in the Sfmbt2 miRNA cluster causes enlargement of cloned mouse placentas.
Volume: 11
Issue: 1
Pages: 2150
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Publication
15273746 | J:91609
First Author: Araki T
Year: 2004
Journal: Nat Med
Title: Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.
Volume: 10
Issue: 8
Pages: 849-57
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Publication
25825741 | J:220534
First Author: Li X
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Gαi1 and Gαi3 regulate macrophage polarization by forming a complex containing CD14 and Gab1.
Volume: 112
Issue: 15
Pages: 4731-6
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Publication
35483741 | J:324527
First Author: Matoba S
Year: 2022
Journal: Genes Dev
Title: Noncanonical imprinting sustains embryonic development and restrains placental overgrowth.
Volume: 36
Issue: 7-8
Pages: 483-494
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Publication
23424281 | J:194528
First Author: Cao C
Year: 2013
Journal: PLoS Biol
Title: Impairment of TrkB-PSD-95 signaling in Angelman syndrome.
Volume: 11
Issue: 2
Pages: e1001478
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Publication
15736129 | J:98531
First Author: Xie Y
Year: 2005
Journal: Mol Reprod Dev
Title: Six post-implantation lethal knockouts of genes for lipophilic MAPK pathway proteins are expressed in preimplantation mouse embryos and trophoblast stem cells.
Volume: 71
Issue: 1
Pages: 1-11
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Publication
12176364 | J:230362
First Author: Berry DM
Year: 2002
Journal: Curr Biol
Title: A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling.
Volume: 12
Issue: 15
Pages: 1336-41
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Publication
15314156 | J:92782
First Author: Higuchi T
Year: 2004
Journal: Mol Cell Biol
Title: MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.
Volume: 24
Issue: 17
Pages: 7456-68
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Publication
26109068 | J:317558
First Author: Mongan M
Year: 2015
Journal: J Biol Chem
Title: Gene-Environment Interactions Target Mitogen-activated Protein 3 Kinase 1 (MAP3K1) Signaling in Eyelid Morphogenesis.
Volume: 290
Issue: 32
Pages: 19770-9
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Publication
26728565 | J:233610
First Author: Peng Y
Year: 2016
Journal: Mol Psychiatry
Title: The autism-associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain.
Volume: 21
Issue: 7
Pages: 925-35
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Publication
23452850 | J:206901
First Author: Findlay GM
Year: 2013
Journal: Cell
Title: Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate.
Volume: 152
Issue: 5
Pages: 1008-20
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Publication
26393505 | J:296619
First Author: Fan Y
Year: 2015
Journal: PLoS Genet
Title: Tissue-Specific Gain of RTK Signalling Uncovers Selective Cell Vulnerability during Embryogenesis.
Volume: 11
Issue: 9
Pages: e1005533
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Publication
29386106 | J:270726
First Author: Shimada IS
Year: 2018
Journal: Cell Rep
Title: Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis.
Volume: 22
Issue: 5
Pages: 1169-1184
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Publication
34193412 | J:314221
 
First Author: Wang Q
Year: 2021
Journal: Sci Adv
Title: Lacrimal gland budding requires PI3K-dependent suppression of EGF signaling.
Volume: 7
Issue: 27
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Publication
30718289 | J:272613
 
First Author: Koutelou E
Year: 2019
Journal: Development
Title: USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta.
Volume: 146
Issue: 4
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Publication
21862448 | J:198109
First Author: Oeschger FM
Year: 2012
Journal: Cereb Cortex
Title: Gene expression analysis of the embryonic subplate.
Volume: 22
Issue: 6
Pages: 1343-59
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Publication
15102471 | J:114108
First Author: Papin J
Year: 2004
Journal: Curr Opin Biotechnol
Title: Bioinformatics and cellular signaling.
Volume: 15
Issue: 1
Pages: 78-81
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Publication
19521500 | J:149737
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Pathway
R-MMU-180292 | GAB1 signalosome
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Publication
25596749 | -
First Author: Chang CH
Year: 2015
Journal: Oncotarget
Title: Gab1 is essential for membrane translocation, activity and integrity of mTORCs after EGF stimulation in urothelial cell carcinoma.
Volume: 6
Issue: 3
Pages: 1478-89
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DO Term
DOID:0110484 | autosomal recessive nonsyndromic deafness 26
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Interaction Experiment
Sachs M (2000)
Description: Essential role of Gab1 for signaling by the c-Met receptor in vivo.
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Interaction Experiment
Holgado-Madruga M (2003)
Description: Gab1 is an integrator of cell death versus cell survival signals in oxidative stress.
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Interaction Experiment
Yu CF (2002)
Description: ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase.
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GXD Expression
GXD Expression
Probe: MGI:7610068
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610080
Age: postnatal adult
Image: 5 Spiral ganglion
Note: Expression co-colocalized with Gab1 and Nefh expression in neural call bodies of spiral ganglion.
Specimen Label: 5 Spiral ganglion
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7610067
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610082
Age: postnatal adult
Image: 5 Spiral ganglion
Note: Expression co-colocalized with Gab1 and Nefh expression in neural call bodies of spiral ganglion.
Specimen Label: 5 Spiral ganglion
Detected: true
Specimen Num: 3
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HT Experiment
E-GEOD-35778 | Genome-wide analysis of dorsal skin gene expression of control and K14-cre:Gab1fl mutant mice
Series Id: GSE35778
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
11896055 | -
First Author: Yu CF
Year: 2002
Journal: J Biol Chem
Title: ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase.
Volume: 277
Issue: 22
Pages: 19382-8
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GXD Expression
GXD Expression
Probe: MGI:7610068
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610080
Age: postnatal adult
Image: 5 Innervation
Note: Expression co-colocalized with Gab1 and Nefh expression in nerve fibers innervating inner hair cells and outer hair cells in cochlear duct.
Specimen Label: 5 Innervation
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:7610067
Assay Type: Immunohistochemistry
Annotation Date: 2024-03-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7610082
Age: postnatal adult
Image: 5 Innervation
Note: Expression co-colocalized with Gab1 and Nefh expression in nerve fibers innervating inner hair cells and outer hair cells in cochlear duct.
Specimen Label: 5 Innervation
Detected: true
Specimen Num: 2
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Protein Coding Gene
MGI:2443160 | Pag1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q3U1F9
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
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Allele
Gab1<tm1Wbm> | MGI:1934204
Name: growth factor receptor bound protein 2-associated protein 1; targeted mutation 1, Walter Birchmeier
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Protein
Q3V3J9
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: false
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Protein Domain
IPR046355 | Gab1-4-like
Type: Family
Description: This entry represents GRB2-associated-binding proteins 1-4 (Gab1-4) and similar proteins from animals. Proteins in this family contain one PH domain. GAB1 from humans and its orthologues dos and soc-1 from Drosophila and C. elegans [], respectively, function as adapter proteins that modulate intracellular signalling cascades triggered by activated receptor-type kinases. Gab1 from human plays a role in FGFR1 signalling, is involved in the MET/HGF-signalling pathway and functions as an important upstream regulator in EGF-mediated activation of mTORCs [, ].
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Genotype
Genotype
Symbol: Gab1/Gab1
Background: involves: 129P2/OlaHsd
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gab1/Gab1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gab1/Gab1<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gab1/Gab1
Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
Zygosity: hm
Has Mutant Allele: true
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Protein
Q9QYY0
Organism: Mus musculus/domesticus
Length: 695  
Fragment?: false
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