|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 1720 for Gata2

0.034s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Allele
Name: regulatory region 249; endonuclease-mediated mutation 2, Emery H Bresnick
Allele Type: Endonuclease-mediated
Attribute String: Modified regulatory region
ncRNA Gene
Type: lncRNA_gene
Organism: mouse, laboratory
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Johnson KD
Year: 2012
Journal: J Clin Invest
Title: Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity.
Volume: 122
Issue: 10
Pages: 3692-704
Publication
First Author: Soukup AA
Year: 2021
Journal: Sci Adv
Title: Conditionally pathogenic genetic variants of a hematopoietic disease-suppressing enhancer.
Volume: 7
Issue: 50
Pages: eabk3521
Publication
First Author: Johnson KD
Year: 2015
Journal: Sci Adv
Title: Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Volume: 1
Issue: 8
Pages: e1500503
Publication
First Author: Mehta C
Year: 2017
Journal: Cell Rep
Title: Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program.
Volume: 20
Issue: 12
Pages: 2966-2979
Publication
First Author: Minegishi N
Year: 1999
Journal: Blood
Title: The mouse GATA-2 gene is expressed in the para-aortic splanchnopleura and aorta-gonads and mesonephros region.
Volume: 93
Issue: 12
Pages: 4196-207
Publication
First Author: Sanalkumar R
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Mechanism governing a stem cell-generating cis-regulatory element.
Volume: 111
Issue: 12
Pages: E1091-100
Publication
First Author: Hewitt KJ
Year: 2017
Journal: Dev Cell
Title: GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.
Volume: 42
Issue: 3
Pages: 213-225.e4
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Publication
First Author: Snow JW
Year: 2011
Journal: Blood
Title: Context-dependent function of "GATA switch" sites in vivo.
Volume: 117
Issue: 18
Pages: 4769-72
Publication
First Author: Hewitt KJ
Year: 2015
Journal: Mol Cell
Title: Hematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell Cistrome.
Volume: 59
Issue: 1
Pages: 62-74
Publication
First Author: Frye M
Year: 2018
Journal: Nat Commun
Title: Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program.
Volume: 9
Issue: 1
Pages: 1511
Publication  
First Author: Li Y
Year: 2022
Journal: Cell Immunol
Title: IL-3 Expands Pre-Basophil and Mast Cell Progenitors by Upregulating the IL-3 Receptor Expression.
Volume: 374
Pages: 104498
Publication
First Author: Snow JW
Year: 2010
Journal: PLoS Genet
Title: A single cis element maintains repression of the key developmental regulator Gata2.
Volume: 6
Issue: 9
Pages: e1001103
Publication
First Author: Fu YK
Year: 2021
Journal: Cell Death Dis
Title: Gata2-L359V impairs primitive and definitive hematopoiesis and blocks cell differentiation in murine chronic myelogenous leukemia model.
Volume: 12
Issue: 6
Pages: 568
Publication
First Author: Nagayama K
Year: 2008
Journal: J Endocrinol
Title: Inhibition of GATA2-dependent transactivation of the TSHbeta gene by ligand-bound estrogen receptor alpha.
Volume: 199
Issue: 1
Pages: 113-25
Publication
First Author: Wilkinson AC
Year: 2013
Journal: Biol Open
Title: Single site-specific integration targeting coupled with embryonic stem cell differentiation provides a high-throughput alternative to in vivo enhancer analyses.
Volume: 2
Issue: 11
Pages: 1229-38
Publication
First Author: Rubel CA
Year: 2016
Journal: Cell Rep
Title: A Gata2-Dependent Transcription Network Regulates Uterine Progesterone Responsiveness and Endometrial Function.
Volume: 17
Issue: 5
Pages: 1414-1425
Publication
First Author: Ohmori S
Year: 2022
Journal: iScience
Title: The Il6 -39 kb enhancer containing clustered GATA2- and PU.1-binding sites is essential for Il6 expression in murine mast cells.
Volume: 25
Issue: 9
Pages: 104942
Publication
First Author: Opdecamp K
Year: 1998
Journal: Mamm Genome
Title: The rat microphthalmia-associated transcription factor gene (Mitf) maps at 4q34-q41 and is mutated in the mib rats.
Volume: 9
Issue: 8
Pages: 617-21
Publication
First Author: Vink CS
Year: 2020
Journal: Cell Rep
Title: Iterative Single-Cell Analyses Define the Transcriptome of the First Functional Hematopoietic Stem Cells.
Volume: 31
Issue: 6
Pages: 107627
Publication
First Author: Moignard V
Year: 2013
Journal: Nat Cell Biol
Title: Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis.
Volume: 15
Issue: 4
Pages: 363-72
Publication
First Author: Billing M
Year: 2016
Journal: Exp Hematol
Title: A network including TGFβ/Smad4, Gata2, and p57 regulates proliferation of mouse hematopoietic progenitor cells.
Volume: 44
Issue: 5
Pages: 399-409.e5
Publication
First Author: Pata I
Year: 1999
Journal: Development
Title: The transcription factor GATA3 is a downstream effector of Hoxb1 specification in rhombomere 4.
Volume: 126
Issue: 23
Pages: 5523-31
Publication
First Author: Wei W
Year: 2011
Journal: Mol Cell Biol
Title: Osteoclast progenitors reside in the peroxisome proliferator-activated receptor γ-expressing bone marrow cell population.
Volume: 31
Issue: 23
Pages: 4692-705
Publication
First Author: Hartmann D
Year: 2016
Journal: Circulation
Title: MicroRNA-Based Therapy of GATA2-Deficient Vascular Disease.
Volume: 134
Issue: 24
Pages: 1973-1990
Publication
First Author: Kaimakis P
Year: 2016
Journal: Blood
Title: Functional and molecular characterization of mouse Gata2-independent hematopoietic progenitors.
Volume: 127
Issue: 11
Pages: 1426-37
Publication
First Author: Ohmori S
Year: 2012
Journal: Mol Cell Biol
Title: Regulation of GATA factor expression is distinct between erythroid and mast cell lineages.
Volume: 32
Issue: 23
Pages: 4742-55
Publication
First Author: Xiao L
Year: 2016
Journal: Oncotarget
Title: The essential role of GATA transcription factors in adult murine prostate.
Volume: 7
Issue: 30
Pages: 47891-47903
Publication
First Author: Ghosh A
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: The GATA transcriptional program dictates cell fate equilibrium to establish the maternal-fetal exchange interface and fetal development.
Volume: 121
Issue: 8
Pages: e2310502121
Publication
First Author: Wozniak RJ
Year: 2007
Journal: J Biol Chem
Title: Context-dependent GATA factor function: combinatorial requirements for transcriptional control in hematopoietic and endothelial cells.
Volume: 282
Issue: 19
Pages: 14665-74
Publication
First Author: Moriguchi T
Year: 2015
Journal: Mol Cell Biol
Title: Progenitor stage-specific activity of a cis-acting double GATA motif for Gata1 gene expression.
Volume: 35
Issue: 5
Pages: 805-15
Publication
First Author: Li HS
Year: 2016
Journal: Eur J Haematol
Title: Loss of c-Kit and bone marrow failure upon conditional removal of the GATA-2 C-terminal zinc finger domain in adult mice.
Volume: 97
Issue: 3
Pages: 261-70
Publication
First Author: Chan YC
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Downregulation of endothelial microRNA-200b supports cutaneous wound angiogenesis by desilencing GATA binding protein 2 and vascular endothelial growth factor receptor 2.
Volume: 32
Issue: 6
Pages: 1372-82
Publication
First Author: Li Y
Year: 2015
Journal: J Immunol
Title: The STAT5-GATA2 pathway is critical in basophil and mast cell differentiation and maintenance.
Volume: 194
Issue: 9
Pages: 4328-38
Publication
First Author: Home P
Year: 2017
Journal: Development
Title: Genetic redundancy of GATA factors in the extraembryonic trophoblast lineage ensures the progression of preimplantation and postimplantation mammalian development.
Volume: 144
Issue: 5
Pages: 876-888
Publication
First Author: Ishijima Y
Year: 2012
Journal: Genes Cells
Title: GATA transcription factors are involved in IgE-dependent mast cell degranulation by enhancing the expression of phospholipase C-γ1.
Volume: 17
Issue: 4
Pages: 285-301
Publication
First Author: Robert-Moreno A
Year: 2008
Journal: EMBO J
Title: Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1.
Volume: 27
Issue: 13
Pages: 1886-95
Publication
First Author: Chatterjee S
Year: 2016
Journal: Cell
Title: Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease.
Volume: 167
Issue: 2
Pages: 355-368.e10
Publication
First Author: Ohneda K
Year: 2014
Journal: Mol Cell Biol
Title: Transcription factor GATA1 is dispensable for mast cell differentiation in adult mice.
Volume: 34
Issue: 10
Pages: 1812-26
Publication
First Author: Koyunlar C
Year: 2023
Journal: Blood Adv
Title: Gata2-regulated Gfi1b expression controls endothelial programming during endothelial-to-hematopoietic transition.
Volume: 7
Issue: 10
Pages: 2082-2093
Publication
First Author: Ling T
Year: 2019
Journal: Blood
Title: Chromatin occupancy and epigenetic analysis reveal new insights into the function of the GATA1 N terminus in erythropoiesis.
Volume: 134
Issue: 19
Pages: 1619-1631
Publication
First Author: Ferreira R
Year: 2007
Journal: Blood
Title: Dynamic regulation of Gata factor levels is more important than their identity.
Volume: 109
Issue: 12
Pages: 5481-90
Publication
First Author: Nottingham WT
Year: 2007
Journal: Blood
Title: Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer.
Volume: 110
Issue: 13
Pages: 4188-97
Publication
First Author: Drogat B
Year: 2010
Journal: Blood
Title: Vegf regulates embryonic erythroid development through Gata1 modulation.
Volume: 116
Issue: 12
Pages: 2141-51
Publication
First Author: Lahti L
Year: 2016
Journal: Development
Title: Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei.
Volume: 143
Issue: 3
Pages: 516-29
Publication
First Author: Nakajima T
Year: 2015
Journal: J Biol Chem
Title: Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
Volume: 290
Issue: 16
Pages: 10368-81
Publication
First Author: Pimanda JE
Year: 2008
Journal: Blood
Title: Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code.
Volume: 112
Issue: 12
Pages: 4512-22
Publication
First Author: Kataoka H
Year: 2011
Journal: Blood
Title: Etv2/ER71 induces vascular mesoderm from Flk1+PDGFRα+ primitive mesoderm.
Volume: 118
Issue: 26
Pages: 6975-86
Publication
First Author: Tsarovina K
Year: 2004
Journal: Development
Title: Essential role of Gata transcription factors in sympathetic neuron development.
Volume: 131
Issue: 19
Pages: 4775-86
Publication
First Author: Janardhan HP
Year: 2017
Journal: J Clin Invest
Title: Hdac3 regulates lymphovenous and lymphatic valve formation.
Volume: 127
Issue: 11
Pages: 4193-4206
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: ArrayExpress
Publication
First Author: Virolainen SM
Year: 2012
Journal: Development
Title: Transcriptional regulatory mechanisms underlying the GABAergic neuron fate in different diencephalic prosomeres.
Volume: 139
Issue: 20
Pages: 3795-805
Publication
First Author: Jacob J
Year: 2009
Journal: Development
Title: Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain.
Volume: 136
Issue: 14
Pages: 2477-85
Publication
First Author: Petracca YL
Year: 2016
Journal: Development
Title: The late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cord.
Volume: 143
Issue: 5
Pages: 880-91
Publication
First Author: Achim K
Year: 2013
Journal: Biol Open
Title: The role of Tal2 and Tal1 in the differentiation of midbrain GABAergic neuron precursors.
Volume: 2
Issue: 10
Pages: 990-7
Publication  
First Author: Kirjavainen A
Year: 2022
Journal: Development
Title: Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons.
Volume: 149
Issue: 14
Publication
First Author: Malik N
Year: 2019
Journal: Sci Rep
Title: mTORC1 activity is essential for erythropoiesis and B cell lineage commitment.
Volume: 9
Issue: 1
Pages: 16917
Publication
First Author: Tikker L
Year: 2020
Journal: J Neurosci
Title: Inactivation of the GATA Cofactor ZFPM1 Results in Abnormal Development of Dorsal Raphe Serotonergic Neuron Subtypes and Increased Anxiety-Like Behavior.
Volume: 40
Issue: 45
Pages: 8669-8682
Publication
First Author: Huber K
Year: 2013
Journal: Dev Biol
Title: The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells.
Volume: 380
Issue: 2
Pages: 286-98
Allele  
Name: GATA binding protein 2; targeted mutation 4.1, Stuart Orkin
Allele Type: Targeted
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Minegishi N
Year: 1998
Journal: J Biol Chem
Title: Alternative promoters regulate transcription of the mouse GATA-2 gene.
Volume: 273
Issue: 6
Pages: 3625-34
Publication
First Author: Tsai FY
Year: 1994
Journal: Nature
Title: An early haematopoietic defect in mice lacking the transcription factor GATA-2.
Volume: 371
Issue: 6494
Pages: 221-6
Publication
First Author: Ling KW
Year: 2004
Journal: J Exp Med
Title: GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells.
Volume: 200
Issue: 7
Pages: 871-82
Publication
First Author: Rodrigues NP
Year: 2005
Journal: Blood
Title: Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis.
Volume: 106
Issue: 2
Pages: 477-84
Publication
First Author: Zhou Y
Year: 1998
Journal: EMBO J
Title: Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA-2 in urogenital development.
Volume: 17
Issue: 22
Pages: 6689-700
Publication
First Author: Minegishi N
Year: 2003
Journal: Blood
Title: Expression and domain-specific function of GATA-2 during differentiation of the hematopoietic precursor cells in midgestation mouse embryos.
Volume: 102
Issue: 3
Pages: 896-905
Publication
First Author: Kitajima K
Year: 2006
Journal: Blood
Title: Redirecting differentiation of hematopoietic progenitors by a transcription factor, GATA-2.
Volume: 107
Issue: 5
Pages: 1857-63
Publication
First Author: Patient RK
Year: 2002
Journal: Curr Opin Genet Dev
Title: The GATA family (vertebrates and invertebrates).
Volume: 12
Issue: 4
Pages: 416-22
GXD Expression    
Probe: MGI:1329110
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604215
Stage: TS15
Assay Id: MGI:1329131
Age: embryonic day 9.5
Image: 4
Specimen Label: -/- yolk sac
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1329110
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604215
Stage: TS15
Assay Id: MGI:1329131
Age: embryonic day 9.5
Image: 4
Specimen Label: +/- yolk sac
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1329110
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604215
Stage: TS15
Assay Id: MGI:1329131
Age: embryonic day 9.5
Image: 4
Specimen Label: +/+ yolk sac
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1329110
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1329131
Age: embryonic day 9.5
Image: 4
Specimen Label: -/-
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1329110
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1329131
Age: embryonic day 9.5
Image: 4
Specimen Label: +/-
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:1329110
Assay Type: RT-PCR
Annotation Date: 1999-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:1329131
Age: embryonic day 9.5
Image: 4
Specimen Label: +/+
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:1329081
Assay Type: RT-PCR
Annotation Date: 1999-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Stage: TS20
Assay Id: MGI:1329609
Age: embryonic day 12.5
Image: 4
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1329081
Assay Type: RT-PCR
Annotation Date: 1999-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Stage: TS20
Assay Id: MGI:1329609
Age: embryonic day 12.5
Image: 4
Specimen Label: +/-
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1329081
Assay Type: RT-PCR
Annotation Date: 1999-02-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Stage: TS20
Assay Id: MGI:1329609
Age: embryonic day 12.5
Image: 4
Specimen Label: -/-
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:2662893
Assay Type: RT-PCR
Annotation Date: 2003-07-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:2664555
Age: embryonic day 9.5
Specimen Label: E9.5 Yolk sac +/+
Detected: true
Specimen Num: 1