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Search results 101 to 199 out of 199 for Gca

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Type Details Score
Allele
Irak2<tm1.1Pcoh> | MGI:5548123
Name: interleukin-1 receptor-associated kinase 2; targeted mutation 1.1, Philip Cohen
Allele Type: Targeted
Attribute String: Hypomorph
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Allele
Pold1<em1Ewht> | MGI:7797727
 
Name: polymerase (DNA directed), delta 1, catalytic subunit; endonuclease-mediated mutation 1, Eileen White
Allele Type: Endonuclease-mediated
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Genotype
Genotype
Symbol: Nkx2-5/Nkx2-5
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:5654498 | B6.RHJ-Cnga3<cpfl5>/BocJ
Attribute String: congenic, spontaneous mutation, mutant strain
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Publication
22509403 | J:187090
First Author: Pang JJ
Year: 2012
Journal: PLoS One
Title: AAV-mediated cone rescue in a naturally occurring mouse model of CNGA3-achromatopsia.
Volume: 7
Issue: 4
Pages: e35250
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Publication
- | J:167197
First Author: Hawes N
Year: 2006
Journal: Invest Ophthalmol Vis Sci
Title: A Point Mutation in the Cnga3 Gene Causes Cone Photoreceptor Function Loss (cpfl5) in Mice
Volume: 47
Issue: 13
Pages: 4579
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Publication
29131863 | J:250907
First Author: Dai X
Year: 2017
Journal: PLoS One
Title: Long-term retinal cone rescue using a capsid mutant AAV8 vector in a mouse model of CNGA3-achromatopsia.
Volume: 12
Issue: 11
Pages: e0188032
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Allele
Lrrk2<tm2.1Dlbe> | MGI:6273308
 
Name: leucine-rich repeat kinase 2; targeted mutation 2.1, Deanna L Benson
Allele Type: Targeted
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Allele
Nlrc4<em2Vnce> | MGI:6508702
Name: NLR family, CARD domain containing 4; endonuclease-mediated mutation 2, Russell Vance
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Publication
34112814 | J:322020
First Author: Lubberding AF
Year: 2021
Journal: Sci Rep
Title: Age-dependent transition from islet insulin hypersecretion to hyposecretion in mice with the long QT-syndrome loss-of-function mutation Kcnq1-A340V.
Volume: 11
Issue: 1
Pages: 12253
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Allele
Prm1<em1Ssha> | MGI:7520861
 
Name: protamine 1; endonuclease-mediated mutation 1, Saher Sue Hammoud
Allele Type: Endonuclease-mediated
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Publication
37348559 | J:352497
First Author: Kim YC
Year: 2023
Journal: J Biol Chem
Title: Transgenic mice lacking FGF15/19-SHP phosphorylation display altered bile acids and gut bacteria, promoting nonalcoholic fatty liver disease.
Volume: 299
Issue: 8
Pages: 104946
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Strain
MGI:7797728 | C57BL/6J-Pold1<em1Ewht>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Cnga3/Cnga3
Background: involves: RHJ/LeJ
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Irak2/?
Background: involves: C57BL/6
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Cnga3/Cnga3
Background: B6.RHJ-Cnga3/BocJ
Zygosity: hm
Has Mutant Allele: true
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Allele
Cycs<tm1Mak> | MGI:3581449
Name: cytochrome c, somatic; targeted mutation 1, Tak W Mak
Allele Type: Targeted
Attribute String: Inserted expressed sequence
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Strain
MGI:5701676 | B6.129P2-Cycs<tm1Mak>/Cnbc
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5701692 | B6;129P2-Cycs<tm1Mak>/Cnbc
Attribute String: targeted mutation, mutant stock
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Publication
18550520 | J:139891
First Author: Kanungo AK
Year: 2008
Journal: J Biol Chem
Title: Inhibition of apoptosome activation protects injured motor neurons from cell death.
Volume: 283
Issue: 32
Pages: 22105-12
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Allele
Ercc3<tm2Jhjh> | MGI:3836429
 
Name: excision repair cross-complementing rodent repair deficiency, complementation group 3; targeted mutation 2, Jan H J Hoeijmakers
Allele Type: Targeted
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Strain
MGI:6273316 | C57BL/6NTac-Lrrk2<tm2.1Dlbe>
Attribute String: coisogenic, mutant strain, targeted mutation
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Allele
Ttk<tm1.1Kops> | MGI:6404032
Name: Ttk protein kinase; targeted mutation 1.1, Geert Kops
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence
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Strain
MGI:6729710 | C57BL/6J-Nlrc4<em2Vnce>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Strain
MGI:6509147 | C57BL/6-Nlrc4<em2Vnce>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Bard1<tm8.1Rjbr> | MGI:7284161
Name: BRCA1 associated RING domain 1; targeted mutation 8.1, Richard J Baer
Allele Type: Targeted
Attribute String: Humanized sequence
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Allele
Pstpip2<em4Tbrd> | MGI:7427582
 
Name: proline-serine-threonine phosphatase-interacting protein 2; endonuclease-mediated mutation 4, Tomas Brdicka
Allele Type: Endonuclease-mediated
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Strain
MGI:7522142 | C57BL/6-Prm1<em1Ssha>
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Htr2a<em3(cre)Blr> | MGI:7543067
Name: 5-hydroxytryptamine (serotonin) receptor 2A; endonuclease-mediated mutation 3, Bryan L Roth
Allele Type: Endonuclease-mediated
Attribute String: Humanized sequence, Recombinase, Reporter
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Genotype
Genotype
Symbol: Cycs/Cycs
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Lrrk2/Lrrk2
Background: C57BL/6NTac-Lrrk2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrc4/Nlrc4
Background: C57BL/6-Nlrc4
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Prm1/Prm1
Background: C57BL/6-Prm1
Zygosity: hm
Has Mutant Allele: true
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Publication
34360834 | J:358897
 
First Author: Wang NK
Year: 2021
Journal: Int J Mol Sci
Title: Mouse Models of Achromatopsia in Addressing Temporal "Point of No Return" in Gene-Therapy.
Volume: 22
Issue: 15
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Strain
MGI:3836618 | B6.129P2-Ercc3<tm2Jhjh>
Attribute String: congenic, targeted mutation
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Genotype
Genotype
Symbol: Ercc3/Ercc3
Background: B6.129P2-Ercc3
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Nlrc4/Nlrc4 Nlrp3/Nlrp3
Background: involves: C57BL/6J * C57BL/6N
Zygosity: cx
Has Mutant Allele: true
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Publication
2016065 | J:23858
First Author: Wood L
Year: 1991
Journal: Gene
Title: Isolation of a mouse genomic clone containing four tRNACys-encoding genes.
Volume: 98
Issue: 2
Pages: 249-52
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Publication
23918981 | J:205798
First Author: Pauls E
Year: 2013
Journal: J Immunol
Title: Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice.
Volume: 191
Issue: 5
Pages: 2717-30
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Publication
15907471 | J:98949
First Author: Hao Z
Year: 2005
Journal: Cell
Title: Specific ablation of the apoptotic functions of cytochrome C reveals a differential requirement for cytochrome C and Apaf-1 in apoptosis.
Volume: 121
Issue: 4
Pages: 579-91
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Publication
31147515 | J:277399
First Author: Gifford CA
Year: 2019
Journal: Science
Title: Oligogenic inheritance of a human heart disease involving a genetic modifier.
Volume: 364
Issue: 6443
Pages: 865-870
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Allele
Fgf2<tm2Doe> | MGI:3512180
Name: fibroblast growth factor 2; targeted mutation 2, Thomas Doetschman
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
33361189 | J:306279
     
First Author: Castillo-Tandazo W
Year: 2020
Journal: Mol Cell Biol
Title: Rothmund-Thomson Syndrome-like RECQL4 truncating mutations cause a haploinsufficient low bone mass phenotype in mice.
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Strain
MGI:6404033 | B6.129P2(SJL)-Ttk<tm1.1Kops>/JlmaJ
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:7284162 | STOCK Bard1<tm8.1Rjbr>/Mmjax
Attribute String: mutant stock, targeted mutation
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Strain
MGI:7543128 | C57BL/6J-Htr2a<em3(cre)Blr>/J
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Ercc3/Ercc3 Xpa/Xpa
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Irak1/? Irak2/?
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Mrtfb/Mrtfb<+> Myh7/Myh7<+> Nkx2-5/Nkx2-5<+>
Background: involves: C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Publication
34582935 | J:331188
 
First Author: Dai X
Year: 2021
Journal: Exp Eye Res
Title: Intraperitoneal chromophore injections delay early-onset and rapid retinal cone degeneration in a mouse model of Leber congenital amaurosis.
Volume: 212
Pages: 108776
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Strain
MGI:4358732 | STOCK Fgf2<tm2Doe>/J
Attribute String: mutant stock, targeted mutation
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Publication
26466960 | J:328369
First Author: Liu X
Year: 2015
Journal: J Immunol
Title: Cytosolic Low Molecular Weight FGF2 Orchestrates RIG-I-Mediated Innate Immune Response.
Volume: 195
Issue: 10
Pages: 4943-52
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Publication
31276497 | J:277473
First Author: Castillo-Tandazo W
Year: 2019
Journal: PLoS Genet
Title: ATP-dependent helicase activity is dispensable for the physiological functions of Recql4.
Volume: 15
Issue: 7
Pages: e1008266
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Allele
Tyr<em19Ove> | MGI:6416505
Name: tyrosinase; endonuclease-mediated mutation 19, Paul Overbeek
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Publication
37460896 | J:338968
First Author: Moritz L
Year: 2023
Journal: Nat Struct Mol Biol
Title: Sperm chromatin structure and reproductive fitness are altered by substitution of a single amino acid in mouse protamine 1.
Volume: 30
Issue: 8
Pages: 1077-1091
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Genotype
Genotype
Symbol: Ercc2/Ercc2 Ercc3/Ercc3
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Fgf2/Fgf2
Background: involves: 129P2/OlaHsd * Black Swiss
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(13Naip1-Naip5)1Vnce/Del(13Naip1-Naip5)1Vnce Nlrc4/Nlrc4
Background: involves: C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
28115719 | J:240876
First Author: Zhang H
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Immunoinhibitory checkpoint deficiency in medium and large vessel vasculitis.
Volume: 114
Issue: 6
Pages: E970-E979
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Publication
15939815 | J:112245
First Author: Tokudome T
Year: 2005
Journal: Circulation
Title: Calcineurin-nuclear factor of activated T cells pathway-dependent cardiac remodeling in mice deficient in guanylyl cyclase A, a receptor for atrial and brain natriuretic peptides.
Volume: 111
Issue: 23
Pages: 3095-104
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Publication
19690065 | J:158488
First Author: Miyashita K
Year: 2009
Journal: Diabetes
Title: Natriuretic peptides/cGMP/cGMP-dependent protein kinase cascades promote muscle mitochondrial biogenesis and prevent obesity.
Volume: 58
Issue: 12
Pages: 2880-92
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Publication
19372206 | J:158158
First Author: Li Y
Year: 2009
Journal: Endocrinology
Title: Guanylyl cyclase-A inhibits angiotensin II type 2 receptor-mediated pro-hypertrophic signaling in the heart.
Volume: 150
Issue: 8
Pages: 3759-65
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Publication
36010661 | J:327915
 
First Author: Jang BG
Year: 2022
Journal: Cells
Title: 2,4-Diacetylphloroglucinol Reduces Beta-Amyloid Production and Secretion by Regulating ADAM10 and Intracellular Trafficking in Cellular and Animal Models of Alzheimer's Disease.
Volume: 11
Issue: 16
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Publication
24492610 | J:210676
First Author: Miller BA
Year: 2014
Journal: J Biol Chem
Title: TRPM2 channels protect against cardiac ischemia-reperfusion injury: role of mitochondria.
Volume: 289
Issue: 11
Pages: 7615-29
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Publication
10591008 | J:58744
First Author: Kurnianto E
Year: 1999
Journal: Exp Anim
Title: Diallel cross analysis of body weight in subspecies of mice.
Volume: 48
Issue: 4
Pages: 277-83
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Publication
12545208 | J:81956
First Author: Al-Khedhairy AA
Year: 2002
Journal: Acta Biochim Pol
Title: Molecular cloning and sequencing of rabbit presenilin-1 cDNA fragment.
Volume: 49
Issue: 4
Pages: 1013-7
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Publication
21346246 | J:172413
First Author: Makino A
Year: 2011
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Regulation of mitochondrial morphology and function by O-GlcNAcylation in neonatal cardiac myocytes.
Volume: 300
Issue: 6
Pages: R1296-302
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Publication
28724574 | J:250037
 
First Author: Wen Z
Year: 2017
Journal: Sci Transl Med
Title: The microvascular niche instructs T cells in large vessel vasculitis via the VEGF-Jagged1-Notch pathway.
Volume: 9
Issue: 399
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Publication
29540721 | J:262566
First Author: Wass C
Year: 2018
Journal: Sci Rep
Title: Dopamine D1 receptor density in the mPFC responds to cognitive demands and receptor turnover contributes to general cognitive ability in mice.
Volume: 8
Issue: 1
Pages: 4533
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Publication
28114323 | J:303454
First Author: Ishikawa A
Year: 2017
Journal: PLoS One
Title: Identification of a Putative Quantitative Trait Gene for Resistance to Obesity in Mice Using Transcriptome Analysis and Causal Inference Tests.
Volume: 12
Issue: 1
Pages: e0170652
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Publication
36852920 | J:334699
First Author: Williams PA
Year: 2023
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Intestinal epithelial autophagy is required for the regenerative benefit of calorie restriction.
Volume: 324
Issue: 5
Pages: G354-G368
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Publication
11821910 | J:76387
First Author: Cervelli M
Year: 2002
Journal: J Mol Evol
Title: Comparative structure analysis of vertebrate U17 small nucleolar RNA (snoRNA).
Volume: 54
Issue: 2
Pages: 166-79
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Publication
29466783 | J:274093
First Author: Liang W
Year: 2018
Journal: Cell Physiol Biochem
Title: Knockout of Low Molecular Weight FGF2 Attenuates Atherosclerosis by Reducing Macrophage Infiltration and Oxidative Stress in Mice.
Volume: 45
Issue: 4
Pages: 1434-1443
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Publication
15073041 | J:94550
First Author: Garmy-Susini B
Year: 2004
Journal: Circ Res
Title: Role of fibroblast growth factor-2 isoforms in the effect of estradiol on endothelial cell migration and proliferation.
Volume: 94
Issue: 10
Pages: 1301-9
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Publication
17150229 | J:119652
First Author: Liao S
Year: 2007
Journal: J Mol Cell Cardiol
Title: The cardioprotective effect of the low molecular weight isoform of fibroblast growth factor-2: the role of JNK signaling.
Volume: 42
Issue: 1
Pages: 106-20
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Publication
19114557 | J:145759
First Author: Andressoo JO
Year: 2009
Journal: Mol Cell Biol
Title: An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair.
Volume: 29
Issue: 5
Pages: 1276-90
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Publication
34860583 | J:335284
First Author: Wang SB
Year: 2021
Journal: Sci Immunol
Title: DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs.
Volume: 6
Issue: 66
Pages: eabi4493
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Publication
25706871 | J:226302
First Author: Dai X
Year: 2015
Journal: PLoS One
Title: The frequency-response electroretinogram distinguishes cone and abnormal rod function in rd12 mice.
Volume: 10
Issue: 2
Pages: e0117570
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Publication
27383589 | J:234639
First Author: Matikainen-Ankney BA
Year: 2016
Journal: J Neurosci
Title: Altered Development of Synapse Structure and Function in Striatum Caused by Parkinson's Disease-Linked LRRK2-G2019S Mutation.
Volume: 36
Issue: 27
Pages: 7128-41
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Publication
24244869 | J:227962
 
First Author: Nusayr E
Year: 2013
Journal: Physiol Rep
Title: FGF2 modulates cardiac remodeling in an isoform- and sex-specific manner.
Volume: 1
Issue: 4
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Publication
24244870 | J:227961
 
First Author: Nusayr E
Year: 2013
Journal: Physiol Rep
Title: Cardiac development and physiology are modulated by FGF2 in an isoform- and sex-specific manner.
Volume: 1
Issue: 4
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Publication
32342103 | J:294930
 
First Author: Tenthorey JL
Year: 2020
Journal: J Exp Med
Title: NLRC4 inflammasome activation is NLRP3- and phosphorylation-independent during infection and does not protect from melanoma.
Volume: 217
Issue: 7
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Strain
MGI:6430102 | STOCK Tyr<em19Ove>/Mmmh
Attribute String: mutant stock, endonuclease-mediated mutation
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Publication
26546009 | J:285777
First Author: Sankaran JS
Year: 2016
Journal: Mamm Genome
Title: Modulation of unloading-induced bone loss in mice with altered ERK signaling.
Volume: 27
Issue: 1-2
Pages: 47-61
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Publication
30144364 | J:322111
First Author: Burt PM
Year: 2019
Journal: J Cell Physiol
Title: Ablation of low-molecular-weight FGF2 isoform accelerates murine osteoarthritis while loss of high-molecular-weight FGF2 isoforms offers protection.
Volume: 234
Issue: 4
Pages: 4418-4431
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Publication
19056741 | J:147213
First Author: Xiao L
Year: 2009
Journal: J Biol Chem
Title: Exported 18-kDa isoform of fibroblast growth factor-2 is a critical determinant of bone mass in mice.
Volume: 284
Issue: 5
Pages: 3170-82
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Publication
19732411 | J:159598
 
First Author: Jen YH
Year: 2009
Journal: Neural Dev
Title: Glypican-1 controls brain size through regulation of fibroblast growth factor signaling in early neurogenesis.
Volume: 4
Pages: 33
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Publication
32198375 | J:286421
First Author: Hoevenaar WHM
Year: 2020
Journal: Nat Commun
Title: Degree and site of chromosomal instability define its oncogenic potential.
Volume: 11
Issue: 1
Pages: 1501
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Publication
36605205 | J:332442
 
First Author: Pavliuchenko N
Year: 2022
Journal: Front Immunol
Title: Molecular interactions of adaptor protein PSTPIP2 control neutrophil-mediated responses leading to autoinflammation.
Volume: 13
Pages: 1035226
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Publication
26320657 | J:254636
First Author: Song X
Year: 2015
Journal: Immunity
Title: Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage.
Volume: 43
Issue: 3
Pages: 488-501
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Publication
30883949 | J:357831
First Author: Kefalakes E
Year: 2019
Journal: Eur J Neurosci
Title: Isoform-selective as opposed to complete depletion of fibroblast growth factor 2 (FGF-2) has no major impact on survival and gene expression in SOD1(G93A) amyotrophic lateral sclerosis mice.
Volume: 50
Issue: 6
Pages: 3028-3045
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Publication
24632563 | J:210320
 
First Author: Josefsson EC
Year: 2014
Journal: Nat Commun
Title: Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways.
Volume: 5
Pages: 3455
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Publication
39561777 | J:359565
     
First Author: Housset M
Year: 2024
Journal: Dev Cell
Title: Identification of a non-canonical planar cell polarity pathway triggered by light in the developing mouse retina.
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Publication
37808655 | J:341620
     
First Author: Chiu YT
Year: 2023
Journal: bioRxiv
Title: A suite of engineered mice for interrogating psychedelic drug actions.
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Publication
- | J:45473
First Author: Lund L
Year: 1997
Journal: Mouse Genome
Title: PCR typing of obese mice
Volume: 95
Issue: 4
Pages: 889-91
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Publication
21052544 | J:166679
 
First Author: Won J
Year: 2011
Journal: J Ophthalmol
Title: Mouse model resources for vision research.
Volume: 2011
Pages: 391384
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Publication
32290105 | J:282558
 
First Author: Collin GB
Year: 2020
Journal: Cells
Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.
Volume: 9
Issue: 4
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Publication
- | J:94077
     
First Author: Mutant Mouse Regional Resource Centers
Year: 2004
Journal: Unpublished
Title: Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC)
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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