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Search results 101 to 200 out of 272 for Gdf15

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Protein Coding Gene
MGP_129S1SvImJ_G0033716 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0033699 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0033624 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0033695 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033405 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1346047 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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•
Protein Coding Gene
MGP_C57BL6NJ_G0034212 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0032730 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033383 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033537 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033478 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0033624 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033521 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034230 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032438 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0032845 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0021621 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032274 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
22952779 | J:191658
First Author: Husaini Y
Year: 2012
Journal: PLoS One
Title: Macrophage inhibitory cytokine-1 (MIC-1/GDF15) slows cancer development but increases metastases in TRAMP prostate cancer prone mice.
Volume: 7
Issue: 8
Pages: e43833
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Publication
23231375 | J:195443
First Author: Rossaint J
Year: 2013
Journal: J Thromb Haemost
Title: GDF-15 prevents platelet integrin activation and thrombus formation.
Volume: 11
Issue: 2
Pages: 335-44
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Publication
16397141 | J:118878
First Author: Kempf T
Year: 2006
Journal: Circ Res
Title: The transforming growth factor-beta superfamily member growth-differentiation factor-15 protects the heart from ischemia/reperfusion injury.
Volume: 98
Issue: 3
Pages: 351-60
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Publication
24504814 | J:330599
First Author: Lambrecht S
Year: 2014
Journal: Arthritis Rheumatol
Title: Growth differentiation factor 15, a marker of lung involvement in systemic sclerosis, is involved in fibrosis development but is not indispensable for fibrosis development.
Volume: 66
Issue: 2
Pages: 418-27
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Publication
21242297 | J:176852
First Author: de Jager SC
Year: 2011
Journal: J Exp Med
Title: Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis.
Volume: 208
Issue: 2
Pages: 217-25
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Publication
19864576 | J:154446
First Author: Strelau J
Year: 2009
Journal: J Neurosci
Title: Progressive postnatal motoneuron loss in mice lacking GDF-15.
Volume: 29
Issue: 43
Pages: 13640-8
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Publication
26077927 | J:309234
First Author: Wang X
Year: 2015
Journal: Cell Tissue Res
Title: Growth/differentiation factor-15 and its role in peripheral nervous system lesion and regeneration.
Volume: 362
Issue: 2
Pages: 317-30
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Publication
26733415 | J:259578
 
First Author: Machado V
Year: 2016
Journal: Neurobiol Dis
Title: Growth/differentiation factor-15 deficiency compromises dopaminergic neuron survival and microglial response in the 6-hydroxydopamine mouse model of Parkinson's disease.
Volume: 88
Pages: 1-15
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Publication
33207247 | J:300248
First Author: Breen DM
Year: 2020
Journal: Cell Metab
Title: GDF-15 Neutralization Alleviates Platinum-Based Chemotherapy-Induced Emesis, Anorexia, and Weight Loss in Mice and Nonhuman Primates.
Volume: 32
Issue: 6
Pages: 938-950.e6
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Publication
17982462 | J:292414
First Author: Johnen H
Year: 2007
Journal: Nat Med
Title: Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1.
Volume: 13
Issue: 11
Pages: 1333-40
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Publication
10524241 | J:57452
First Author: Böttner M
Year: 1999
Journal: Gene
Title: Characterization of the rat, mouse, and human genes of growth/differentiation factor-15/macrophage inhibiting cytokine-1 (GDF-15/MIC-1).
Volume: 237
Issue: 1
Pages: 105-11
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Publication
19074584 | J:151817
First Author: Ding Q
Year: 2009
Journal: Endocrinology
Title: Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes.
Volume: 150
Issue: 4
Pages: 1688-96
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Publication
20431030 | J:161327
First Author: Huh SJ
Year: 2010
Journal: Am J Pathol
Title: Macrophage inhibitory cytokine-1 regulates melanoma vascular development.
Volume: 176
Issue: 6
Pages: 2948-57
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Publication
24236027 | J:209210
First Author: Zhou Z
Year: 2013
Journal: PLoS One
Title: Growth differentiation factor-15 suppresses maturation and function of dendritic cells and inhibits tumor-specific immune response.
Volume: 8
Issue: 11
Pages: e78618
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Publication
26154268 | J:319153
First Author: Kim DH
Year: 2015
Journal: Stem Cells Dev
Title: GDF-15 secreted from human umbilical cord blood mesenchymal stem cells delivered through the cerebrospinal fluid promotes hippocampal neurogenesis and synaptic activity in an Alzheimer's disease model.
Volume: 24
Issue: 20
Pages: 2378-90
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2669437
Age: postnatal adult
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2669437
Age: postnatal adult
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2669437
Age: postnatal adult
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2669437
Age: postnatal adult
Specimen Label: 4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1885228
Stage: TS28
Assay Id: MGI:2669437
Age: postnatal adult
Specimen Label: 5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2669437
Age: postnatal adult
Specimen Label: 6
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2669437
Age: postnatal adult
Specimen Label: 7
Detected: true
Specimen Num: 7
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•
GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:2669437
Age: postnatal adult
Specimen Label: 8
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:2669437
Age: postnatal adult
Specimen Label: 9
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:2669438
Age: postnatal adult
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:2669438
Age: postnatal adult
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:2669438
Age: postnatal adult
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:2669438
Age: postnatal adult
Specimen Label: 5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689628
Stage: TS28
Assay Id: MGI:2669438
Age: postnatal adult
Specimen Label: 6
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2669439
Age: embryonic day 16.0
Specimen Label: 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684624
Stage: TS24
Assay Id: MGI:2669439
Age: embryonic day 16.0
Specimen Label: 2
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737324
Stage: TS24
Assay Id: MGI:2669439
Age: embryonic day 16.0
Specimen Label: 3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754424
Stage: TS24
Assay Id: MGI:2669439
Age: embryonic day 16.0
Specimen Label: 4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267824
Stage: TS24
Assay Id: MGI:2669439
Age: embryonic day 16.0
Specimen Label: 5
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1697424
Stage: TS24
Assay Id: MGI:2669439
Age: embryonic day 16.0
Specimen Label: 6
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
     
Probe: MGI:2669436
Assay Type: RT-PCR
Annotation Date: 2003-08-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267828
Stage: TS28
Assay Id: MGI:2669438
Age: postnatal adult
Specimen Label: 4
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691463
Age: postnatal adult
Image: MRC Harwell_1311841
Note: kidney
Specimen Label: MRC Harwell_1311841
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691463
Age: postnatal adult
Image: MRC Harwell_1311839
Specimen Label: MRC Harwell_1311839
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1702128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691463
Age: postnatal adult
Image: MRC Harwell_1311840
Specimen Label: MRC Harwell_1311840
Detected: true
Specimen Num: 1
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Publication
24496615 | J:221296
First Author: Carrillo-García C
Year: 2014
Journal: Development
Title: Growth/differentiation factor 15 promotes EGFR signalling, and regulates proliferation and migration in the hippocampus of neonatal and young adult mice.
Volume: 141
Issue: 4
Pages: 773-83
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Publication
33593916 | J:316128
 
First Author: Sabatini PV
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: GFRAL-expressing neurons suppress food intake via aversive pathways.
Volume: 118
Issue: 8
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Publication
35472437 | J:324679
 
First Author: He R
Year: 2022
Journal: Cancer Lett
Title: SULF2 enhances GDF15-SMAD axis to facilitate the initiation and progression of pancreatic cancer.
Volume: 538
Pages: 215693
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Publication
23316317 | J:312603
First Author: Bonaterra GA
Year: 2012
Journal: J Am Heart Assoc
Title: Growth differentiation factor-15 deficiency inhibits atherosclerosis progression by regulating interleukin-6-dependent inflammatory response to vascular injury.
Volume: 1
Issue: 6
Pages: e002550
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Publication
21516086 | J:171576
First Author: Kempf T
Year: 2011
Journal: Nat Med
Title: GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice.
Volume: 17
Issue: 5
Pages: 581-8
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Publication
34571994 | J:312554
 
First Author: Heduschke A
Year: 2021
Journal: Cells
Title: GDF-15 Deficiency Reduces Autophagic Activity in Human Macrophages In Vitro and Decreases p62-Accumulation in Atherosclerotic Lesions in Mice.
Volume: 10
Issue: 9
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Publication
38013040 | J:343646
 
First Author: Reyes J
Year: 2023
Journal: Brain Behav Immun
Title: Growth differentiation factor-15 is an IFN-γ regulated mediator of infection-induced weight loss and the hepatic FGF21 response.
Volume: 116
Pages: 24-33
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Publication
28223503 | J:241649
First Author: Morrow RM
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity.
Volume: 114
Issue: 10
Pages: 2705-2710
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Publication
19375854 | J:150685
First Author: Iguchi G
Year: 2009
Journal: Cancer Lett
Title: A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2.
Volume: 282
Issue: 2
Pages: 152-8
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Publication
23791946 | J:245356
First Author: Chu ML
Year: 2013
Journal: Structure
Title: structural Studies of Wnts and identification of an LRP6 binding site.
Volume: 21
Issue: 7
Pages: 1235-42
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Publication
- | J:166124
     
First Author: Taconic Biosciences
Year: 2010
Journal: Unpublished
Title: Information obtained from Taconic Biosciences
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Publication
27235139 | J:236115
First Author: Artz A
Year: 2016
Journal: Blood
Title: GDF-15 inhibits integrin activation and mouse neutrophil recruitment through the ALK-5/TGF-βRII heterodimer.
Volume: 128
Issue: 4
Pages: 529-41
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Publication
33151561 | J:302564
First Author: Lee J
Year: 2021
Journal: J Cell Physiol
Title: Macrophage inhibitory cytokine-1 promotes angiogenesis by eliciting the GFRAL-mediated endothelial cell signaling.
Volume: 236
Issue: 5
Pages: 4008-4023
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Publication
28771943 | J:278252
 
First Author: Romaine A
Year: 2018
Journal: Acta Physiol (Oxf)
Title: Overexpression of integrin α11 induces cardiac fibrosis in mice.
Volume: 222
Issue: 2
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Publication
32929274 | J:305853
First Author: Harb H
Year: 2020
Journal: Nat Immunol
Title: A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.
Volume: 21
Issue: 11
Pages: 1359-1370
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Publication
31155355 | J:294396
First Author: Chang KC
Year: 2019
Journal: Curr Biol
Title: Opposing Effects of Growth and Differentiation Factors in Cell-Fate Specification.
Volume: 29
Issue: 12
Pages: 1963-1975.e5
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Publication
23844157 | J:204300
First Author: Ge Y
Year: 2013
Journal: PLoS One
Title: RNAi screen reveals potentially novel roles of cytokines in myoblast differentiation.
Volume: 8
Issue: 7
Pages: e68068
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Publication
32464196 | J:300508
 
First Author: Hilliard SA
Year: 2020
Journal: Mech Dev
Title: Mdm4 controls ureteric bud branching via regulation of p53 activity.
Volume: 163
Pages: 103616
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Publication
27120339 | J:248734
First Author: Bolt CC
Year: 2016
Journal: PLoS One
Title: Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate.
Volume: 11
Issue: 4
Pages: e0154413
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Publication
26657772 | J:240000
First Author: Park JY
Year: 2016
Journal: Development
Title: The apical complex protein Pals1 is required to maintain cerebellar progenitor cells in a proliferative state.
Volume: 143
Issue: 1
Pages: 133-46
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Publication
15342483 | J:108109
First Author: Oxburgh L
Year: 2004
Journal: Development
Title: TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population.
Volume: 131
Issue: 18
Pages: 4593-605
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
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First Author: Wellcome Trust Sanger Institute
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Title: Nomenclature Committee Use
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Title: Mouse Gene Trap Data Load from dbGSS
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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