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Search results 101 to 200 out of 1513 for Gdnf

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Type Details Score
Publication  
First Author: Chermenina M
Year: 2014
Journal: Neuroscience
Title: GDNF is important for striatal organization and maintenance of dopamine neurons grown in the presence of the striatum.
Volume: 270
Pages: 1-11
Gene
Type: gene
Organism: human
Publication
First Author: Hanbury R
Year: 2003
Journal: J Comp Neurol
Title: GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults.
Volume: 461
Issue: 3
Pages: 307-16
Publication
First Author: Goto A
Year: 2013
Journal: J Neurosci
Title: GDNF and endothelin 3 regulate migration of enteric neural crest-derived cells via protein kinase A and Rac1.
Volume: 33
Issue: 11
Pages: 4901-12
Publication
First Author: Li L
Year: 2019
Journal: Nat Metab
Title: Muscle stem cell renewal suppressed by Gas1 can be reversed by GDNF in mice.
Volume: 1
Issue: 10
Pages: 985-995
Publication
First Author: Luukko K
Year: 1997
Journal: Dev Dyn
Title: Expression of GDNF and its receptors in developing tooth is developmentally regulated and suggests multiple roles in innervation and organogenesis.
Volume: 210
Issue: 4
Pages: 463-71
Publication
First Author: Chi L
Year: 2004
Journal: Development
Title: Sprouty proteins regulate ureteric branching by coordinating reciprocal epithelial Wnt11, mesenchymal Gdnf and stromal Fgf7 signalling during kidney development.
Volume: 131
Issue: 14
Pages: 3345-56
Protein
Organism: Mus musculus/domesticus
Length: 464  
Fragment?: false
Publication
First Author: Lu BC
Year: 2009
Journal: Nat Genet
Title: Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis.
Volume: 41
Issue: 12
Pages: 1295-302
Publication
First Author: Parsadanian A
Year: 2006
Journal: Exp Neurol
Title: Astrocyte-derived transgene GDNF promotes complete and long-term survival of adult facial motoneurons following avulsion and differentially regulates the expression of transcription factors of AP-1 and ATF/CREB families.
Volume: 200
Issue: 1
Pages: 26-37
Publication  
First Author: Naumenko VS
Year: 2014
Journal: Behav Brain Res
Title: Effect of GDNF on depressive-like behavior, spatial learning and key genes of the brain dopamine system in genetically predisposed to behavioral disorders mouse strains.
Volume: 274
Pages: 1-9
Publication
First Author: Emmerson PJ
Year: 2017
Journal: Nat Med
Title: The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.
Volume: 23
Issue: 10
Pages: 1215-1219
Publication
First Author: Kobayashi H
Year: 2007
Journal: Mech Dev
Title: Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects.
Volume: 124
Issue: 4
Pages: 290-303
Publication  
First Author: Stewart AL
Year: 2008
Journal: BMC Dev Biol
Title: Effects of NGF, NT-3 and GDNF family members on neurite outgrowth and migration from pelvic ganglia from embryonic and newborn mice.
Volume: 8
Pages: 73
Protein
Organism: Mus musculus/domesticus
Length: 393  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 225  
Fragment?: true
Publication
First Author: Meng X
Year: 2000
Journal: Science
Title: Regulation of cell fate decision of undifferentiated spermatogonia by GDNF.
Volume: 287
Issue: 5457
Pages: 1489-93
Publication
First Author: Widenfalk J
Year: 1997
Journal: J Neurosci
Title: Neurturin and glial cell line-derived neurotrophic factor receptor-beta (GDNFR-beta), novel proteins related to GDNF and GDNFR-alpha with specific cellular patterns of expression suggesting roles in the developing and adult nervous system and in peripheral organs.
Volume: 17
Issue: 21
Pages: 8506-19
Publication
First Author: Pichel JG
Year: 1996
Journal: Nature
Title: Defects in enteric innervation and kidney development in mice lacking GDNF.
Volume: 382
Issue: 6586
Pages: 73-6
Publication
First Author: Yang L
Year: 2017
Journal: Nat Med
Title: GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.
Volume: 23
Issue: 10
Pages: 1158-1166
Publication
First Author: Mullican SE
Year: 2017
Journal: Nat Med
Title: GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates.
Volume: 23
Issue: 10
Pages: 1150-1157
Protein
Organism: Mus musculus/domesticus
Length: 246  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 309  
Fragment?: false
Publication
First Author: Moore MW
Year: 1996
Journal: Nature
Title: Renal and neuronal abnormalities in mice lacking GDNF.
Volume: 382
Issue: 6586
Pages: 76-9
Protein
Organism: Mus musculus/domesticus
Length: 468  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 478  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 425  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 420  
Fragment?: false
Publication
First Author: Sánchez MP
Year: 1996
Journal: Nature
Title: Renal agenesis and the absence of enteric neurons in mice lacking GDNF.
Volume: 382
Issue: 6586
Pages: 70-3
Publication
First Author: Whitehead J
Year: 2005
Journal: Mech Dev
Title: Glial cell-line derived neurotrophic factor-dependent fusimotor neuron survival during development.
Volume: 122
Issue: 1
Pages: 27-41
Publication  
First Author: Igual Gil C
Year: 2022
Journal: Life Sci Alliance
Title: Mitochondrial stress-induced GFRAL signaling controls diurnal food intake and anxiety-like behavior.
Volume: 5
Issue: 11
Protein
Organism: Mus musculus/domesticus
Length: 463  
Fragment?: false
Publication
First Author: Wang H
Year: 2010
Journal: J Neurosci
Title: The timing and location of glial cell line-derived neurotrophic factor expression determine enteric nervous system structure and function.
Volume: 30
Issue: 4
Pages: 1523-38
Publication
First Author: Klein RD
Year: 1997
Journal: Nature
Title: A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor.
Volume: 387
Issue: 6634
Pages: 717-21
Publication
First Author: Langsdorf A
Year: 2011
Journal: Glycobiology
Title: Expression regulation and function of heparan sulfate 6-O-endosulfatases in the spermatogonial stem cell niche.
Volume: 21
Issue: 2
Pages: 152-61
Publication
First Author: Grieshammer U
Year: 2004
Journal: Dev Cell
Title: SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site.
Volume: 6
Issue: 5
Pages: 709-17
Publication
First Author: Zwick M
Year: 2002
Journal: J Neurosci
Title: Glial cell line-derived neurotrophic factor is a survival factor for isolectin B4-positive, but not vanilloid receptor 1-positive, neurons in the mouse.
Volume: 22
Issue: 10
Pages: 4057-65
Publication
First Author: Albers KM
Year: 2006
Journal: J Neurosci
Title: Glial cell-line-derived neurotrophic factor expression in skin alters the mechanical sensitivity of cutaneous nociceptors.
Volume: 26
Issue: 11
Pages: 2981-90
Protein
Organism: Mus musculus/domesticus
Length: 190  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 293  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 302  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 269  
Fragment?: false
Publication
First Author: Vrieseling E
Year: 2006
Journal: Cell
Title: Target-induced transcriptional control of dendritic patterning and connectivity in motor neurons by the ETS gene Pea3.
Volume: 127
Issue: 7
Pages: 1439-52
Publication
First Author: Uesaka T
Year: 2007
Journal: Development
Title: Conditional ablation of GFRalpha1 in postmigratory enteric neurons triggers unconventional neuronal death in the colon and causes a Hirschsprung's disease phenotype.
Volume: 134
Issue: 11
Pages: 2171-81
Publication
First Author: Helmbacher F
Year: 2003
Journal: Neuron
Title: Met signaling is required for recruitment of motor neurons to PEA3-positive motor pools.
Volume: 39
Issue: 5
Pages: 767-77
Publication
First Author: Natarajan D
Year: 2002
Journal: Development
Title: Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis.
Volume: 129
Issue: 22
Pages: 5151-60
Publication
First Author: Nishiyama C
Year: 2012
Journal: Nat Neurosci
Title: Trans-mesenteric neural crest cells are the principal source of the colonic enteric nervous system.
Volume: 15
Issue: 9
Pages: 1211-8
Publication
First Author: Enterría-Morales D
Year: 2020
Journal: Brain Commun
Title: Molecular targets for endogenous glial cell line-derived neurotrophic factor modulation in striatal parvalbumin interneurons.
Volume: 2
Issue: 2
Pages: fcaa105
Publication
First Author: Hoshi M
Year: 2012
Journal: Development
Title: Novel mechanisms of early upper and lower urinary tract patterning regulated by RetY1015 docking tyrosine in mice.
Volume: 139
Issue: 13
Pages: 2405-15
Publication
First Author: Buj-Bello A
Year: 1997
Journal: Nature
Title: Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase.
Volume: 387
Issue: 6634
Pages: 721-4
Publication
First Author: Cabrera JR
Year: 2006
Journal: J Biol Chem
Title: Gas1 is related to the glial cell-derived neurotrophic factor family receptors alpha and regulates Ret signaling.
Volume: 281
Issue: 20
Pages: 14330-9
Protein Domain
Type: Homologous_superfamily
Description: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) receptors are potent survival factors for sympathetic, sensory and central nervous system neurons [, ]. GDNF and neurturin promote neuronal survival by signalling through similar multicomponent receptors that consist of a common receptor tyrosine kinase and a member of a GPI-linked family of receptors that determines ligand specificity [].Structurally, GDNF is composed of five helices with an irregular disulfide-linked array. It is topologically similar to the fungal elicitin fold ().
Publication
First Author: Langsdorf A
Year: 2011
Journal: Am J Respir Cell Mol Biol
Title: Neural crest cell origin and signals for intrinsic neurogenesis in the mammalian respiratory tract.
Volume: 44
Issue: 3
Pages: 293-301
Publication
First Author: Gonzalez-Reyes LE
Year: 2012
Journal: Neuron
Title: Sonic hedgehog maintains cellular and neurochemical homeostasis in the adult nigrostriatal circuit.
Volume: 75
Issue: 2
Pages: 306-19
Publication
First Author: Donnelly CR
Year: 2019
Journal: J Dent Res
Title: Ret Signaling Is Required for Tooth Pulp Innervation during Organogenesis.
Volume: 98
Issue: 6
Pages: 705-712
Publication
First Author: Zhang H
Year: 2019
Journal: Dev Cell
Title: FAT4 Fine-Tunes Kidney Development by Regulating RET Signaling.
Volume: 48
Issue: 6
Pages: 780-792.e4
Gene
Type: gene
Organism: frog, African clawed
Publication
First Author: Taketomi T
Year: 2005
Journal: Nat Neurosci
Title: Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia.
Volume: 8
Issue: 7
Pages: 855-7
Publication
First Author: Kramer ER
Year: 2006
Journal: Neuron
Title: Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb.
Volume: 50
Issue: 1
Pages: 35-47
Publication
First Author: Sergaki MC
Year: 2017
Journal: Cell Rep
Title: GFRα1 Regulates Purkinje Cell Migration by Counteracting NCAM Function.
Volume: 18
Issue: 2
Pages: 367-379
Publication
First Author: Donnelly CR
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Biphasic functions for the GDNF-Ret signaling pathway in chemosensory neuron development and diversification.
Volume: 115
Issue: 3
Pages: E516-E525
Protein
Organism: Mus musculus/domesticus
Length: 359  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 331  
Fragment?: false
Publication
First Author: Naughton CK
Year: 2006
Journal: Biol Reprod
Title: Glial cell-line derived neurotrophic factor-mediated RET signaling regulates spermatogonial stem cell fate.
Volume: 74
Issue: 2
Pages: 314-21
Publication
First Author: Gould TW
Year: 2008
Journal: J Neurosci
Title: The neurotrophic effects of glial cell line-derived neurotrophic factor on spinal motoneurons are restricted to fusimotor subtypes.
Volume: 28
Issue: 9
Pages: 2131-46
Publication
First Author: Hellmich HL
Year: 1996
Journal: Mech Dev
Title: Embryonic expression of glial cell-line derived neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial-mesenchymal interactions.
Volume: 54
Issue: 1
Pages: 95-105
Publication
First Author: Matsushita N
Year: 1997
Journal: Gene
Title: Cloning and structural organization of the gene encoding the mouse glial cell line-derived neurotrophic factor, GDNF.
Volume: 203
Issue: 2
Pages: 149-57
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Cebrian C
Year: 2014
Journal: Cell Rep
Title: The number of fetal nephron progenitor cells limits ureteric branching and adult nephron endowment.
Volume: 7
Issue: 1
Pages: 127-37
Publication
First Author: Kotzbauer PT
Year: 1996
Journal: Nature
Title: Neurturin, a relative of glial-cell-line-derived neurotrophic factor.
Volume: 384
Issue: 6608
Pages: 467-70
Publication
First Author: Drinkut A
Year: 2016
Journal: Cell Death Dis
Title: Ret is essential to mediate GDNF's neuroprotective and neuroregenerative effect in a Parkinson disease mouse model.
Volume: 7
Issue: 9
Pages: e2359
Publication
First Author: Heuckeroth RO
Year: 1997
Journal: Genomics
Title: Neurturin, a novel neurotrophic factor, is localized to mouse chromosome 17 and human chromosome 19p13.3.
Volume: 44
Issue: 1
Pages: 137-40
Publication
First Author: Watabe K
Year: 1995
Journal: J Neurosci Res
Title: Spontaneously immortalized adult mouse Schwann cells secrete autocrine and paracrine growth-promoting activities.
Volume: 41
Issue: 2
Pages: 279-90
Publication
First Author: Suzuki H
Year: 1998
Journal: J Comp Neurol
Title: Prominent expression of glial cell line-derived neurotrophic factor in human skeletal muscle.
Volume: 402
Issue: 3
Pages: 303-12
Publication
First Author: Quintero EM
Year: 2004
Journal: Neuroscience
Title: Glial cell line-derived neurotrophic factor is essential for neuronal survival in the locus coeruleus-hippocampal noradrenergic pathway.
Volume: 124
Issue: 1
Pages: 137-46
Publication  
First Author: Sotoyama H
Year: 2017
Journal: Neurosci Lett
Title: Striatal hypodopamine phenotypes found in transgenic mice that overexpress glial cell line-derived neurotrophic factor.
Volume: 654
Pages: 99-106
Publication  
First Author: Meir M
Year: 2021
Journal: Int J Mol Sci
Title: Intestinal Epithelial Barrier Maturation by Enteric Glial Cells Is GDNF-Dependent.
Volume: 22
Issue: 4
Publication
First Author: Huang L
Year: 2005
Journal: Neuroscience
Title: Glial cell line-derived neurotrophic factor (GDNF) is required for differentiation of pontine noradrenergic neurons and patterning of central respiratory output.
Volume: 130
Issue: 1
Pages: 95-105
Publication  
First Author: Buhusi M
Year: 2017
Journal: Front Behav Neurosci
Title: Impaired Latent Inhibition in GDNF-Deficient Mice Exposed to Chronic Stress.
Volume: 11
Pages: 177
Publication
First Author: Granholm AC
Year: 1997
Journal: J Neurosci
Title: Morphological alterations in the peripheral and central nervous systems of mice lacking glial cell line-derived neurotrophic factor (GDNF): immunohistochemical studies.
Volume: 17
Issue: 3
Pages: 1168-78
Publication
First Author: Boger HA
Year: 2007
Journal: J Neurosci
Title: Long-term consequences of methamphetamine exposure in young adults are exacerbated in glial cell line-derived neurotrophic factor heterozygous mice.
Volume: 27
Issue: 33
Pages: 8816-25
Publication
First Author: af Bjerkén S
Year: 2007
Journal: Brain Res
Title: Effects of glial cell line-derived neurotrophic factor deletion on ventral mesencephalic organotypic tissue cultures.
Volume: 1133
Issue: 1
Pages: 10-9
Publication
First Author: Airavaara M
Year: 2007
Journal: Genes Brain Behav
Title: Effects of repeated morphine on locomotion, place preference and dopamine in heterozygous glial cell line-derived neurotrophic factor knockout mice.
Volume: 6
Issue: 3
Pages: 287-98
Publication
First Author: Michael L
Year: 2007
Journal: J Anat
Title: The lectin Dolichos biflorus agglutinin is a sensitive indicator of branching morphogenetic activity in the developing mouse metanephric collecting duct system.
Volume: 210
Issue: 1
Pages: 89-97
Publication
First Author: Tanaka M
Year: 2000
Journal: Brain Res Mol Brain Res
Title: Promoter analysis and characteristics of the 5'-untranslated region of the mouse glial cell line-derived neurotrophic factor gene.
Volume: 85
Issue: 1-2
Pages: 91-102
Publication
First Author: Chun HS
Year: 2002
Journal: Exp Neurol
Title: Marked dopaminergic cell loss subsequent to developmental, intranigral expression of glial cell line-derived neurotrophic factor.
Volume: 173
Issue: 2
Pages: 235-44
Publication
First Author: Lonka-Nevalaita L
Year: 2010
Journal: J Neurosci
Title: Characterization of the intracellular localization, processing, and secretion of two glial cell line-derived neurotrophic factor splice isoforms.
Volume: 30
Issue: 34
Pages: 11403-13
Publication
First Author: Salio C
Year: 2014
Journal: J Neurosci
Title: Presynaptic modulation of spinal nociceptive transmission by glial cell line-derived neurotrophic factor (GDNF).
Volume: 34
Issue: 41
Pages: 13819-33
Publication
First Author: Mwangi SM
Year: 2016
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Glial cell line-derived neurotrophic factor protects against high-fat diet-induced hepatic steatosis by suppressing hepatic PPAR-γ expression.
Volume: 310
Issue: 2
Pages: G103-16
Publication
First Author: Hantman AW
Year: 2010
Journal: Nat Neurosci
Title: Clarke's column neurons as the focus of a corticospinal corollary circuit.
Volume: 13
Issue: 10
Pages: 1233-9
Publication
First Author: Menshykau D
Year: 2019
Journal: Nat Commun
Title: Image-based modeling of kidney branching morphogenesis reveals GDNF-RET based Turing-type mechanism and pattern-modulating WNT11 feedback.
Volume: 10
Issue: 1
Pages: 239
Publication
First Author: Broome JD
Year: 1999
Journal: Brain Res Dev Brain Res
Title: Glial cell line-derived neurotrophic factor protects midbrain dopamine neurons from the lethal action of the weaver gene: a quantitative immunocytochemical study.
Volume: 116
Issue: 1
Pages: 1-7
Publication
First Author: Rajan I
Year: 2001
Journal: Pediatr Dev Pathol
Title: RET(Men2B)-transgene produces sympathoadrenal tumors but does not prevent intestinal aganglionosis in gdnf-/- or gfr alpha-1(-/-) mice.
Volume: 4
Issue: 5
Pages: 446-53
Publication
First Author: Anitha M
Year: 2006
Journal: Gastroenterology
Title: Glial-derived neurotrophic factor modulates enteric neuronal survival and proliferation through neuropeptide Y.
Volume: 131
Issue: 4
Pages: 1164-78
Publication
First Author: Shepherd IT
Year: 2001
Journal: Dev Biol
Title: Functional analysis of zebrafish GDNF.
Volume: 231
Issue: 2
Pages: 420-35
Publication  
First Author: Buhusi M
Year: 2016
Journal: Front Behav Neurosci
Title: Stress-Induced Executive Dysfunction in GDNF-Deficient Mice, A Mouse Model of Parkinsonism.
Volume: 10
Pages: 114
Publication
First Author: Gil Z
Year: 2010
Journal: J Natl Cancer Inst
Title: Paracrine regulation of pancreatic cancer cell invasion by peripheral nerves.
Volume: 102
Issue: 2
Pages: 107-18
Publication
First Author: Cullen-McEwen LA
Year: 2001
Journal: Kidney Int
Title: Nephron endowment in glial cell line-derived neurotrophic factor (GDNF) heterozygous mice.
Volume: 60
Issue: 1
Pages: 31-6