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Search results 101 to 200 out of 201 for Gpat3

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1775122
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3274122
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287422
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3266022
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1624622
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Note: Expression was not detected in the digestive system.
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1721422
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1646922
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1736222
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1683322
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1700022
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1832122
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876522
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Note: Expression was not detected in the immune system.
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1741222
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754022
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599822
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3280922
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1833322
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287022
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752522
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1821522
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
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•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3557722
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702122
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1756322
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1668822
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1802422
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
•
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:4427340
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2672022
Stage: TS22
Assay Id: MGI:5422377
Age: embryonic day 14.5
Note: Expression was not detected in whisker follicle.
Specimen Label: EG2769; Specimen G0855
Detected: false
Specimen Num: 1
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Publication
11003606 | J:296154
First Author: Starodub O
Year: 2000
Journal: Am J Physiol Cell Physiol
Title: Sterol carrier protein-2 localization in endoplasmic reticulum and role in phospholipid formation.
Volume: 279
Issue: 4
Pages: C1259-69
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Publication
30523059 | J:273892
First Author: Quiroga IY
Year: 2019
Journal: Biochem J
Title: Glycerol-3-phosphate acyltransferases 3 and 4 direct glycerolipid synthesis and affect functionality in activated macrophages.
Volume: 476
Issue: 1
Pages: 85-99
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Publication
28930673 | J:251809
First Author: Lodhi IJ
Year: 2017
Journal: Cell Rep
Title: PexRAP Inhibits PRDM16-Mediated Thermogenic Gene Expression.
Volume: 20
Issue: 12
Pages: 2766-2774
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
18156367 | J:130874
First Author: Soupene E
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Mammalian acyl-CoA:lysophosphatidylcholine acyltransferase enzymes.
Volume: 105
Issue: 1
Pages: 88-93
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Publication
18238778 | J:135331
First Author: Chen YQ
Year: 2008
Journal: J Biol Chem
Title: AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase.
Volume: 283
Issue: 15
Pages: 10048-57
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Publication
25491198 | -
 
First Author: Moessinger C
Year: 2014
Journal: BMC Cell Biol
Title: Two different pathways of phosphatidylcholine synthesis, the Kennedy Pathway and the Lands Cycle, differentially regulate cellular triacylglycerol storage.
Volume: 15
Pages: 43
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Publication
21498505 | -
First Author: Moessinger C
Year: 2011
Journal: J Biol Chem
Title: Human lysophosphatidylcholine acyltransferases 1 and 2 are located in lipid droplets where they catalyze the formation of phosphatidylcholine.
Volume: 286
Issue: 24
Pages: 21330-9
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Protein Domain
IPR045252 | LPCAT1-like
Type: Domain
Description: Proteins containing this domain include lysophosphatidylcholine acyltransferase 1 (LPCAT1) and related proteins. LPCAT1 exhibits acyltransferase activity [], []and is involved in LD (lipid droplet)-associated lipid metabolism [, ]. Proteins containing this domain also includes glycerol-3-phosphate acyltransferases, such as GPAT3 and GPAT4, which are involved in de novo triacylglycerol synthesis [, ].
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Protein
Q6NVG1
Organism: Mus musculus/domesticus
Length: 524  
Fragment?: false
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Protein
Q8C0N2
Organism: Mus musculus/domesticus
Length: 438  
Fragment?: false
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Protein
Q8K2C8
Organism: Mus musculus/domesticus
Length: 456  
Fragment?: false
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Protein
Q3TSI4
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: true
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Protein
Q3TIF6
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: false
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Protein
Q6PEU9
Organism: Mus musculus/domesticus
Length: 336  
Fragment?: true
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Protein
O35259
Organism: Mus musculus/domesticus
Length: 294  
Fragment?: false
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Publication
24939733 | J:215498
First Author: Zhang C
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor.
Volume: 307
Issue: 3
Pages: E305-15
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Publication
25559747 | J:337999
 
First Author: Ma S
Year: 2015
Journal: Sci Rep
Title: Thyrotropin and obesity: increased adipose triglyceride content through glycerol-3-phosphate acyltransferase 3.
Volume: 5
Pages: 7633
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Protein
Q9CT84
Organism: Mus musculus/domesticus
Length: 228  
Fragment?: true
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Publication
16294310 | -
First Author: Gully D
Year: 2006
Journal: Proteomics
Title: A protein network for phospholipid synthesis uncovered by a variant of the tandem affinity purification method in Escherichia coli.
Volume: 6
Issue: 1
Pages: 282-93
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Publication
15687349 | -
First Author: Liu D
Year: 2005
Journal: J Lipid Res
Title: Role of dihydroxyacetonephosphate acyltransferase in the biosynthesis of plasmalogens and nonether glycerolipids.
Volume: 46
Issue: 4
Pages: 727-35
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Publication
9536089 | J:47622
First Author: Ofman R
Year: 1998
Journal: Hum Mol Genet
Title: Acyl-CoA:dihydroxyacetonephosphate acyltransferase: cloning of the human cDNA and resolution of the molecular basis in rhizomelic chondrodysplasia punctata type 2.
Volume: 7
Issue: 5
Pages: 847-53
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Publication
12874108 | J:84690
First Author: Rodemer C
Year: 2003
Journal: Hum Mol Genet
Title: Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice.
Volume: 12
Issue: 15
Pages: 1881-95
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Publication
30813330 | -
 
First Author: Karasawa K
Year: 2019
Journal: Int J Mol Sci
Title: Transcriptional Regulation of Acyl-CoA:Glycerol-sn-3-Phosphate Acyltransferases.
Volume: 20
Issue: 4
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Publication
32817111 | -
 
First Author: Noga MJ
Year: 2020
Journal: mBio
Title: Posttranslational Control of PlsB Is Sufficient To Coordinate Membrane Synthesis with Growth in Escherichia coli.
Volume: 11
Issue: 4
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Protein
A0A494BAR5
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: true
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Protein Domain
IPR022284 | GPAT/DHAPAT
Type: Family
Description: This entry represents the Glycerol-3-phosphate O-acyltransferase/dihydroxyacetone phosphate acyltransferase (GPAT/DAPAT) family. This entry includes PlsB, a GPAT from E. coli in which membrane synthesis depends on allosteric control of this enzyme. PlsB regulation plays an important role in the phospholipid synthesis pathway and is part of the response to certain stress signals []. In many other bacteria, PlsB is not found, and appears to be replaced by a two enzyme system for 1-acyl-glycerol-3-phosphate biosynthesis, the PlsX/Y system [, ].GPATs are classified into four isoforms in mammals; GPAT1 and GPAT2 are localized in the mitochondrial outer membrane, whereas GPAT3 and GPAT4 are localized in the endoplasmic reticulum membrane []. This entry includes the mitochondrial isoform, GPAT1 and GPAT2.Dihydroxyacetonephosphate acyltransferase (DHAPAT) catalyses the first step in the biosynthesis of ether phospholipid plasmalogen, and may play also a significant role in nonether glycerolipid biosynthesis [, ]. In humans, mutations in DHAPAT results in the genetic disorder rhizomelic chondrodysplasia punctata type 2, characterised by rhizomelic shortening of femur and humerus, cataract,and severe mental retardation [].
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Protein Domain
IPR045520 | GPAT/DHAPAT_C
Type: Domain
Description: This entry represents the C-terminal domain of glycerol-3-phosphate acyltransferases (GPATs) and dihydroxyacetone phosphate acyltransferases.Dihydroxyacetonephosphate acyltransferase (DHAPAT) catalyses the first step in the biosynthesis of ether phospholipid plasmalogen, and may play also a significant role in nonether glycerolipid biosynthesis [, ]. In humans, mutations in DHAPAT results in the genetic disorder rhizomelic chondrodysplasia punctata type 2, characterised by rhizomelic shortening of femur and humerus, cataract,and severe mental retardation [].This entry includes PlsB, a GPAT from E. coli in which membrane synthesis depends on allosteric control of this enzyme. PlsB regulation plays an important role in the phospholipid synthesis pathway and is part of the response to certain stress signals []. In many other bacteria, PlsB is not found, and appears to be replaced by a two enzyme system for 1-acyl-glycerol-3-phosphate biosynthesis, the PlsX/Y system [, ].GPATs are classified into four isoforms in mammals; GPAT1 and GPAT2 are localized in the mitochondrial outer membrane, whereas GPAT3 and GPAT4 are localized in the endoplasmic reticulum membrane []. This entry includes the mitochondrial isoform GPAT.
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Protein
P98192
Organism: Mus musculus/domesticus
Length: 678  
Fragment?: false
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Protein
Q61586
Organism: Mus musculus/domesticus
Length: 827  
Fragment?: false
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Protein
A0A494BA32
Organism: Mus musculus/domesticus
Length: 681  
Fragment?: false
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Protein
Q545P6
Organism: Mus musculus/domesticus
Length: 678  
Fragment?: false
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Protein
Q69ZG4
Organism: Mus musculus/domesticus
Length: 848  
Fragment?: true
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Protein
Q3TKG9
Organism: Mus musculus/domesticus
Length: 678  
Fragment?: false
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Protein
Q3UBU1
Organism: Mus musculus/domesticus
Length: 678  
Fragment?: false
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Protein
Q8R390
Organism: Mus musculus/domesticus
Length: 678  
Fragment?: false
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Protein
Q05DV2
Organism: Mus musculus/domesticus
Length: 585  
Fragment?: true
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Publication
16949372 | -
First Author: Lu YJ
Year: 2006
Journal: Mol Cell
Title: Acyl-phosphates initiate membrane phospholipid synthesis in Gram-positive pathogens.
Volume: 23
Issue: 5
Pages: 765-72
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Protein
Q14DK4
Organism: Mus musculus/domesticus
Length: 801  
Fragment?: false
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Protein
Q8BYI6
Organism: Mus musculus/domesticus
Length: 544  
Fragment?: false
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Protein
Q3TFD2
Organism: Mus musculus/domesticus
Length: 534  
Fragment?: false
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Protein
Q9D5U0
Organism: Mus musculus/domesticus
Length: 516  
Fragment?: false
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Protein
B2RT16
Organism: Mus musculus/domesticus
Length: 516  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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