Type |
Details |
Score |
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
456
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Shiozaki Y |
Year: |
2020 |
Journal: |
iScience |
Title: |
GPAT4-Generated Saturated LPAs Induce Lipotoxicity through Inhibition of Autophagy by Abnormal Formation of Omegasomes. |
Volume: |
23 |
Issue: |
5 |
Pages: |
101105 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
228
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Gully D |
Year: |
2006 |
Journal: |
Proteomics |
Title: |
A protein network for phospholipid synthesis uncovered by a variant of the tandem affinity purification method in Escherichia coli. |
Volume: |
6 |
Issue: |
1 |
Pages: |
282-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu D |
Year: |
2005 |
Journal: |
J Lipid Res |
Title: |
Role of dihydroxyacetonephosphate acyltransferase in the biosynthesis of plasmalogens and nonether glycerolipids. |
Volume: |
46 |
Issue: |
4 |
Pages: |
727-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ofman R |
Year: |
1998 |
Journal: |
Hum Mol Genet |
Title: |
Acyl-CoA:dihydroxyacetonephosphate acyltransferase: cloning of the human cDNA and resolution of the molecular basis in rhizomelic chondrodysplasia punctata type 2. |
Volume: |
7 |
Issue: |
5 |
Pages: |
847-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rodemer C |
Year: |
2003 |
Journal: |
Hum Mol Genet |
Title: |
Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice. |
Volume: |
12 |
Issue: |
15 |
Pages: |
1881-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Karasawa K |
Year: |
2019 |
Journal: |
Int J Mol Sci |
Title: |
Transcriptional Regulation of Acyl-CoA:Glycerol-sn-3-Phosphate Acyltransferases. |
Volume: |
20 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Noga MJ |
Year: |
2020 |
Journal: |
mBio |
Title: |
Posttranslational Control of PlsB Is Sufficient To Coordinate Membrane Synthesis with Growth in Escherichia coli. |
Volume: |
11 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Anunciado-Koza RP |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
Diet-induced adipose tissue expansion is mitigated in mice with a targeted inactivation of mesoderm specific transcript (Mest). |
Volume: |
12 |
Issue: |
6 |
Pages: |
e0179879 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
124
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents the Glycerol-3-phosphate O-acyltransferase/dihydroxyacetone phosphate acyltransferase (GPAT/DAPAT) family. This entry includes PlsB, a GPAT from E. coli in which membrane synthesis depends on allosteric control of this enzyme. PlsB regulation plays an important role in the phospholipid synthesis pathway and is part of the response to certain stress signals []. In many other bacteria, PlsB is not found, and appears to be replaced by a two enzyme system for 1-acyl-glycerol-3-phosphate biosynthesis, the PlsX/Y system [, ].GPATs are classified into four isoforms in mammals; GPAT1 and GPAT2 are localized in the mitochondrial outer membrane, whereas GPAT3 and GPAT4 are localized in the endoplasmic reticulum membrane []. This entry includes the mitochondrial isoform, GPAT1 and GPAT2.Dihydroxyacetonephosphate acyltransferase (DHAPAT) catalyses the first step in the biosynthesis of ether phospholipid plasmalogen, and may play also a significant role in nonether glycerolipid biosynthesis [, ]. In humans, mutations in DHAPAT results in the genetic disorder rhizomelic chondrodysplasia punctata type 2, characterised by rhizomelic shortening of femur and humerus, cataract,and severe mental retardation []. |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Domain |
Description: |
This entry represents the C-terminal domain of glycerol-3-phosphate acyltransferases (GPATs) and dihydroxyacetone phosphate acyltransferases.Dihydroxyacetonephosphate acyltransferase (DHAPAT) catalyses the first step in the biosynthesis of ether phospholipid plasmalogen, and may play also a significant role in nonether glycerolipid biosynthesis [, ]. In humans, mutations in DHAPAT results in the genetic disorder rhizomelic chondrodysplasia punctata type 2, characterised by rhizomelic shortening of femur and humerus, cataract,and severe mental retardation [].This entry includes PlsB, a GPAT from E. coli in which membrane synthesis depends on allosteric control of this enzyme. PlsB regulation plays an important role in the phospholipid synthesis pathway and is part of the response to certain stress signals []. In many other bacteria, PlsB is not found, and appears to be replaced by a two enzyme system for 1-acyl-glycerol-3-phosphate biosynthesis, the PlsX/Y system [, ].GPATs are classified into four isoforms in mammals; GPAT1 and GPAT2 are localized in the mitochondrial outer membrane, whereas GPAT3 and GPAT4 are localized in the endoplasmic reticulum membrane []. This entry includes the mitochondrial isoform GPAT. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
678
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
827
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
681
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
678
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
848
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
678
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
678
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
678
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
585
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu YJ |
Year: |
2006 |
Journal: |
Mol Cell |
Title: |
Acyl-phosphates initiate membrane phospholipid synthesis in Gram-positive pathogens. |
Volume: |
23 |
Issue: |
5 |
Pages: |
765-72 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
801
 |
Fragment?: |
false |
|
•
•
•
•
•
|