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Search results 101 to 173 out of 173 for Gpr119

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:3001928
Stage: TS28
Assay Id: MGI:5540578
Age: postnatal day 84
Image: GUDMAP:14908
Specimen Label: GUDMAP:14908
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2825426
Stage: TS26
Assay Id: MGI:5540578
Age: embryonic day 17.5
Image: GUDMAP:14907
Specimen Label: GUDMAP:14907
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2825428
Stage: TS28
Assay Id: MGI:5540578
Age: postnatal day 84
Image: GUDMAP:14908
Specimen Label: GUDMAP:14908
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2813626
Stage: TS26
Assay Id: MGI:5540578
Age: embryonic day 17.5
Image: GUDMAP:14907
Specimen Label: GUDMAP:14907
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2813628
Stage: TS28
Assay Id: MGI:5540578
Age: postnatal day 84
Image: GUDMAP:14908
Specimen Label: GUDMAP:14908
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2826026
Stage: TS26
Assay Id: MGI:5540578
Age: embryonic day 17.5
Image: GUDMAP:14907
Specimen Label: GUDMAP:14907
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2826028
Stage: TS28
Assay Id: MGI:5540578
Age: postnatal day 84
Image: GUDMAP:14908
Specimen Label: GUDMAP:14908
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2814226
Stage: TS26
Assay Id: MGI:5540578
Age: embryonic day 17.5
Image: GUDMAP:14907
Specimen Label: GUDMAP:14907
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2814228
Stage: TS28
Assay Id: MGI:5540578
Age: postnatal day 84
Image: GUDMAP:14908
Specimen Label: GUDMAP:14908
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1897626
Stage: TS26
Assay Id: MGI:5540578
Age: embryonic day 17.5
Image: GUDMAP:14907
Specimen Label: GUDMAP:14907
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:1897628
Stage: TS28
Assay Id: MGI:5540578
Age: postnatal day 84
Image: GUDMAP:14908
Specimen Label: GUDMAP:14908
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2969128
Stage: TS28
Assay Id: MGI:5540578
Age: postnatal day 84
Image: GUDMAP:14908
Specimen Label: GUDMAP:14908
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692769
Age: postnatal adult
Image: UC Davis_1877350
Specimen Label: UC Davis_1877350
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2826626
Stage: TS26
Assay Id: MGI:5540578
Age: embryonic day 17.5
Image: GUDMAP:14907
Specimen Label: GUDMAP:14907
Detected: false
Specimen Num: 1
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Male
Emaps: EMAPS:2826628
Stage: TS28
Assay Id: MGI:5540578
Age: postnatal day 84
Image: GUDMAP:14908
Specimen Label: GUDMAP:14908
Detected: false
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:4422401
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2772126
Stage: TS26
Assay Id: MGI:5540578
Age: embryonic day 17.5
Image: GUDMAP:14907
Specimen Label: GUDMAP:14907
Detected: false
Specimen Num: 1
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Publication
- | J:84584
   
First Author: Fredriksson R
Year: 2003
Journal: GenBank Submission
Title: Mus musculus G protein-coupled receptor 119 (Gpr119) mRNA, complete cds
Pages: AY288423
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Publication
31740614 | J:282520
First Author: Grevengoed TJ
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis.
Volume: 116
Issue: 49
Pages: 24770-24778
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Publication
27893106 | J:254677
First Author: Miller S
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Evidence for a GPR18 Role in Diurnal Regulation of Intraocular Pressure.
Volume: 57
Issue: 14
Pages: 6419-6426
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Allele
Gpr119<em1Ikim> | MGI:7429201
Name: G-protein coupled receptor 119; endonuclease-mediated mutation 1, Ikuo Kimura
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
23321696 | J:195887
First Author: Larco DO
Year: 2013
Journal: Endocrinology
Title: The metabolite GnRH-(1-5) inhibits the migration of immortalized GnRH neurons.
Volume: 154
Issue: 2
Pages: 783-95
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Publication
23382219 | J:194542
First Author: Ghai R
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Volume: 110
Issue: 8
Pages: E643-52
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
29471473 | J:258677
First Author: Tough IR
Year: 2018
Journal: Endocrinology
Title: Bidirectional GPR119 Agonism Requires Peptide YY and Glucose for Activity in Mouse and Human Colon Mucosa.
Volume: 159
Issue: 4
Pages: 1704-1717
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Publication
31613319 | J:281759
First Author: Murakami T
Year: 2019
Journal: Endocrinology
Title: Noninvasive Evaluation of GPR119 Agonist Effects on β-Cell Mass in Diabetic Male Mice Using 111In-Exendin-4 SPECT/CT.
Volume: 160
Issue: 12
Pages: 2959-2968
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Publication
27677765 | J:237357
First Author: McKillop AM
Year: 2016
Journal: Diabetologia
Title: Metabolic effects of orally administered small-molecule agonists of GPR55 and GPR119 in multiple low-dose streptozotocin-induced diabetic and incretin-receptor-knockout mice.
Volume: 59
Issue: 12
Pages: 2674-2685
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Allele
Tg(Ins1-GPR119)6Mrl | MGI:6434343
Name: transgene insertion 6, Merck Research Laboratory
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Ins1-GPR119)10Mrl | MGI:6434466
Name: transgene insertion 10, Merck Research Laboratory
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:6438385 | C57BL/6-Tg(Ins1-GPR119)10Mrl/Tac
Attribute String: mutant strain, coisogenic, transgenic
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Strain
MGI:6438384 | C57BL/6-Tg(Ins1-GPR119)6Mrl/Tac
Attribute String: mutant strain, coisogenic, transgenic
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Publication
20519124 | J:160909
First Author: Cox HM
Year: 2010
Journal: Cell Metab
Title: Peptide YY is critical for acylethanolamine receptor Gpr119-induced activation of gastrointestinal mucosal responses.
Volume: 11
Issue: 6
Pages: 532-42
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Publication
22876318 | J:248691
First Author: Sykaras AG
Year: 2012
Journal: PLoS One
Title: Duodenal enteroendocrine I-cells contain mRNA transcripts encoding key endocannabinoid and fatty acid receptors.
Volume: 7
Issue: 8
Pages: e42373
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Publication
19805329 | J:153225
First Author: Whyte LS
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo.
Volume: 106
Issue: 38
Pages: 16511-6
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Protein Domain
IPR028334 | GPR55
Type: Family
Description: Several 7TM receptors have been cloned but theirendogenous ligands are unknown; these have been termed orphan receptors. However, recent research has identified certain pharmacological targets that could be investigated to find, for example, new potential cannabinoid receptors or channels [, , ]. GPR18 [, ], GPR55 [, ], GPR119 []show little structural similarity to CB1 and CB2 receptors, but they respond to endogenous agents analogous to the endogenous cannabinoid ligands, as well as some natural/synthetic cannabinoid receptor ligands []. However, because they do not fulfill all of the cannabinoid receptor criteria defined by IUPHAR, the classification of these proteins remains a contentious issue due to conflicting pharmacological results. As a result, they remain classified as putative endogenous agonists by IUPHAR [].This entry represents G protein-coupled receptor 55. It is thought to play a role in bone physiology by regulating osteoclast number and function [].
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Publication
28676689 | J:253706
First Author: Onodera T
Year: 2017
Journal: Sci Rep
Title: Eicosapentaenoic acid and 5-HEPE enhance macrophage-mediated Treg induction in mice.
Volume: 7
Issue: 1
Pages: 4560
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Publication
21540554 | J:173912
First Author: Ali S
Year: 2011
Journal: J Clin Invest
Title: Dual elimination of the glucagon and GLP-1 receptors in mice reveals plasticity in the incretin axis.
Volume: 121
Issue: 5
Pages: 1917-29
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Publication
26294669 | J:228801
First Author: Wang F
Year: 2015
Journal: Am J Physiol Gastrointest Liver Physiol
Title: The role of apolipoprotein A-IV in regulating glucagon-like peptide-1 secretion.
Volume: 309
Issue: 8
Pages: G680-7
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Publication
16844083 | -
First Author: Kohno M
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Identification of N-arachidonylglycine as the endogenous ligand for orphan G-protein-coupled receptor GPR18.
Volume: 347
Issue: 3
Pages: 827-32
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Publication
18187165 | -
First Author: Burstein S
Year: 2008
Journal: Neuropharmacology
Title: The elmiric acids: biologically active anandamide analogs.
Volume: 55
Issue: 8
Pages: 1259-64
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Publication
19379823 | -
First Author: Bradshaw HB
Year: 2009
Journal: Prostaglandins Other Lipid Mediat
Title: Orphan endogenous lipids and orphan GPCRs: a good match.
Volume: 89
Issue: 3-4
Pages: 131-4
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Publication
23396314 | -
First Author: Southern C
Year: 2013
Journal: J Biomol Screen
Title: Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein-coupled receptors.
Volume: 18
Issue: 5
Pages: 599-609
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Publication
19286662 | -
First Author: Yin H
Year: 2009
Journal: J Biol Chem
Title: Lipid G protein-coupled receptor ligand identification using beta-arrestin PathHunter assay.
Volume: 284
Issue: 18
Pages: 12328-38
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Publication
22014123 | -
First Author: Alexander SP
Year: 2012
Journal: Br J Pharmacol
Title: So what do we call GPR18 now?
Volume: 165
Issue: 8
Pages: 2411-3
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Publication
23686350 | -
First Author: Davenport AP
Year: 2013
Journal: Pharmacol Rev
Title: International Union of Basic and Clinical Pharmacology. LXXXVIII. G protein-coupled receptor list: recommendations for new pairings with cognate ligands.
Volume: 65
Issue: 3
Pages: 967-86
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Protein Domain
IPR028335 | GPR18
Type: Family
Description: Several 7TM receptors have been cloned but their endogenous ligands are unknown; these have been termed orphan receptors. However, recent research has identified certain pharmacological targets that could be investigated to find, for example, new potential cannabinoid receptors or channels [, , ]. GPR18 [, ], GPR55 [, ], GPR119 []show little structural similarity to CB1 and CB2 receptors, but they respond to endogenous agents analogous to the endogenous cannabinoid ligands, as well as some natural/synthetic cannabinoid receptor ligands []. However, because they do not fulfill all of the cannabinoid receptor criteria defined by IUPHAR, the classification of these proteins remains a contentious issue due to conflicting pharmacological results. As a result, they remain classified as putative endogenous agonists by IUPHAR [].This entry represents G protein-coupled receptor 18, also known as N-arachidonyl glycine receptor. It has been found to be a receptor for endogenous lipid neurotransmitters, several of which also bind to cannabinoid receptors [, , , ]. Recent research also supports the hypothesis that GPR18 is the abnormal cannabidiol receptor and N-arachidonoyl glycine, the endogenous lipid metabolite of anandamide, initiates directed microglial migration in the CNS through activation of GPR18 []. However, the pairing of GPR18 with N-arachidonoylglycine (NAGly) and tetrahydrocannabinol (THC) was not reproduced in two studies based on beta-arrestin assays [, ]. So, until further research allows a more definitive decision the function and nomenclature GPR18 is still being debated [, ].
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Publication
32278655 | J:302482
 
First Author: Panaro BL
Year: 2020
Journal: Mol Metab
Title: Intestine-selective reduction of Gcg expression reveals the importance of the distal gut for GLP-1 secretion.
Volume: 37
Pages: 100990
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Protein
Q8K1Z6
Organism: Mus musculus/domesticus
Length: 331  
Fragment?: false
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Protein
Q3UJF0
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Protein
Q14BW0
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Protein
Q14BV9
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Publication
- | J:147112
     
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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