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Search results 101 to 200 out of 214 for Grb14

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:7797357
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-06
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1750322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7797850
Age: embryonic day 14.5
Image: 2E
Specimen Label: 2E
Detected: true
Specimen Num: 5
•
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:7797357
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7797850
Age: embryonic day 14.5
Note: Expression is in the endocrine pancreas.
Specimen Label: Table 1
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5000772
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5541332
Age: embryonic day 16.0
Image: GUDMAP:8401
Note: ubiquitous testis expression
Specimen Label: GUDMAP:8401
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7797357
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7797850
Age: embryonic day 14.5
Image: 2B
Specimen Label: 2B
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7797357
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7797850
Age: embryonic day 14.5
Image: 2A
Note: Expression is at the apical surface of the choroid plexus epithelial layer.
Specimen Label: 2A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7797357
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3274122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7797850
Age: embryonic day 14.5
Note: Expression is at the apical epithelial surface.
Specimen Label: Table 1
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_05
Specimen Label: euxassay_012213_05
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_06
Specimen Label: euxassay_012213_06
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_07
Specimen Label: euxassay_012213_07
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_08
Specimen Label: euxassay_012213_08
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_09
Specimen Label: euxassay_012213_09
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_13
Specimen Label: euxassay_012213_13
Detected: true
Specimen Num: 10
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_14
Specimen Label: euxassay_012213_14
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_15
Specimen Label: euxassay_012213_15
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_16
Specimen Label: euxassay_012213_16
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_17
Specimen Label: euxassay_012213_17
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_18
Specimen Label: euxassay_012213_18
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7797357
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-06
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3292822
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7797850
Age: embryonic day 14.5
Note: Expression is in the lower gut.
Specimen Label: Table 1
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_02
Specimen Label: euxassay_012213_02
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_03
Specimen Label: euxassay_012213_03
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_04
Specimen Label: euxassay_012213_04
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_05
Specimen Label: euxassay_012213_05
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_06
Specimen Label: euxassay_012213_06
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_07
Specimen Label: euxassay_012213_07
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_08
Specimen Label: euxassay_012213_08
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_16
Specimen Label: euxassay_012213_16
Detected: true
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_17
Specimen Label: euxassay_012213_17
Detected: true
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_18
Specimen Label: euxassay_012213_18
Detected: true
Specimen Num: 15
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_19
Specimen Label: euxassay_012213_19
Detected: true
Specimen Num: 16
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_20
Specimen Label: euxassay_012213_20
Detected: true
Specimen Num: 17
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1679723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_21
Specimen Label: euxassay_012213_21
Detected: true
Specimen Num: 18
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7797357
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7797850
Age: postnatal day 21
Image: 3C
Specimen Label: 3C
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7797357
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599822
Stage: TS22
Assay Id: MGI:7797850
Age: embryonic day 14.5
Specimen Label: Table 1
Detected: false
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:5000772
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1929024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5541332
Age: embryonic day 16.0
Image: GUDMAP:8401
Note: epithelium, spotty mesenchyme pattern
Specimen Label: GUDMAP:8401
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_07
Specimen Label: euxassay_012213_07
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_08
Specimen Label: euxassay_012213_08
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_14
Specimen Label: euxassay_012213_14
Detected: true
Specimen Num: 11
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4423810
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825216
Age: embryonic day 14.5
Image: euxassay_012213_15
Specimen Label: euxassay_012213_15
Detected: true
Specimen Num: 12
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7797357
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7797850
Age: embryonic day 14.5
Image: 2A
Specimen Label: 2A
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7797357
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-06
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3273022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7797850
Age: embryonic day 14.5
Note: Expression is in ossified cartilage.
Specimen Label: Table 1
Detected: true
Specimen Num: 7
•
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•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:7797357
Assay Type: Immunohistochemistry
Annotation Date: 2025-01-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757722
Stage: TS22
Assay Id: MGI:7797850
Age: embryonic day 14.5
Specimen Label: Table 1
Detected: false
Specimen Num: 7
•
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Publication
20237330 | J:172261
First Author: Lin RC
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: PI3K(p110 alpha) protects against myocardial infarction-induced heart failure: identification of PI3K-regulated miRNA and mRNA.
Volume: 30
Issue: 4
Pages: 724-32
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Publication
17535812 | J:124616
First Author: Kebache S
Year: 2007
Journal: J Biol Chem
Title: Grb10 and active Raf-1 kinase promote Bad-dependent cell survival.
Volume: 282
Issue: 30
Pages: 21873-83
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Publication
10521483 | J:200516
First Author: Jones N
Year: 1999
Journal: J Biol Chem
Title: Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration.
Volume: 274
Issue: 43
Pages: 30896-905
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Publication
21451961 | J:171917
First Author: Mollah MB
Year: 2011
Journal: Mamm Genome
Title: Intersubspecific subcongenic mouse strain analysis reveals closely linked QTLs with opposite effects on body weight.
Volume: 22
Issue: 5-6
Pages: 282-9
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Publication
16214126 | J:103817
First Author: Nef S
Year: 2005
Journal: Dev Biol
Title: Gene expression during sex determination reveals a robust female genetic program at the onset of ovarian development.
Volume: 287
Issue: 2
Pages: 361-77
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Publication
16284245 | J:103829
First Author: Chen B
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.
Volume: 102
Issue: 47
Pages: 17184-9
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
16919269 | J:112701
First Author: Bailey PJ
Year: 2006
Journal: Exp Cell Res
Title: A global genomic transcriptional code associated with CNS-expressed genes.
Volume: 312
Issue: 16
Pages: 3108-19
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
20973951 | -
 
First Author: Sturk C
Year: 2010
Journal: Cell Commun Signal
Title: Tyrosine phosphorylation of Grb14 by Tie2.
Volume: 8
Pages: 30
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Allele
Grb14<em1Smoc> | MGI:7290005
Name: growth factor receptor bound protein 14; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6475426 | C57BL/6JSmoc-Grb14<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Fgfr2<em2Sor> | MGI:7549361
Name: fibroblast growth factor receptor 2; endonuclease-mediated mutation 2, Philippe Soriano
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Strain
MGI:7549363 | 129S4/SvJae-Fgfr2<em2Sor>/Mmucd
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Protein
F2Z3X7
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: true
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Protein
Q3TS23
Organism: Mus musculus/domesticus
Length: 201  
Fragment?: false
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Publication
15469846 | -
First Author: Lafuente EM
Year: 2004
Journal: Dev Cell
Title: RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion.
Volume: 7
Issue: 4
Pages: 585-95
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Protein Domain
IPR039664 | GRB/APBB1IP
Type: Family
Description: Proteins in this entry consist of a Ras-associated (RA) domain, a PH domain, a family-specific BPS region, and a C-terminal SH2 domain. Grb7, Grb10 and Grb14 are paralogues that are also present in this entry []. These adapter proteins bind a variety of receptor tyrosine kinases, including the insulin and insulin-like growth factor-1 (IGF1) receptors. Grb10 and Grb14 are important tissue-specific negative regulators of insulin and IGF1 signaling based and may contribute to type 2 (non-insulin-dependent) diabetes in humans. RA-PH function as a single structural unit and is dimerized via a helical extension of the PH domain. The PH domain here are proposed to bind phosphoinositides non-cannonically and are unlikely to bind an activated GTPase []. This entry also includes APBB1IP (also known as RIAM), which functions in the signal transduction from Ras activation to actin cytoskeletal remodelling [].
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Publication
23747250 | J:199244
First Author: Ezzat S
Year: 2013
Journal: Cell Metab
Title: The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes.
Volume: 17
Issue: 6
Pages: 929-40
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Publication
37421147 | J:338808
 
First Author: Clark JF
Year: 2023
Journal: Biol Open
Title: FRS2-independent GRB2 interaction with FGFR2 is not required for embryonic development.
Volume: 12
Issue: 7
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Protein Domain
IPR035034 | Grb14_SH2
Type: Domain
Description: This entry represents the SH2 domain of Grb14. The Grb7 (growth factor receptor-bound 7) family includes Grb7, Grb10, and Grb14. These are adapter proteins mediating signal transduction from multiple cell surface receptors to diverse downstream pathways. They are composed of an N-terminal proline-rich domain, a Ras Associating-like (RA) domain, a Pleckstrin Homology (PH) domain, a PIR (phosphorylated insulin receptor interacting region) domain (also known as the family-specific BPS region), and a C-terminal SH2 domain []. Grb14 binds to various receptor tyrosine kinases (RTKs) under ligand induction. This interaction involves the SH2 and PIR domains [].
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Protein
B1ATS7
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: true
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Protein
B1ATS8
Organism: Mus musculus/domesticus
Length: 84  
Fragment?: true
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Protein
Q5SUW0
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: true
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Protein Domain
IPR039665 | PH_APBB1IP
Type: Domain
Description: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1IP) consists of a Ras-associated (RA) domain, a PH domain, a family-specific BPS region, and a C-terminal SH2 domain. Grb7, Grb10 and Grb14 are paralogues that are also present in this entry []. These adapter proteins bind a variety of receptor tyrosine kinases, including the insulin and insulin-like growth factor-1 (IGF1) receptors. Grb10 and Grb14 are important tissue-specific negative regulators of insulin and IGF1 signaling based and may contribute to type 2 (non-insulin-dependent) diabetes in humans. RA-PH function as a single structural unit and is dimerized via a helical extension of the PH domain. The PH domain here are proposed to bind phosphoinositides non-cannonically and are unlikely to bind an activated GTPase []. The tandem RA-PH domains are present in a second adapter-protein family, MRL proteins, Caenorhabditis elegansprotein MIG-1012, the mammalian proteins RIAM and lamellipodin and the Drosophila melanogasterprotein Pico12, all of which are Ena/VASP-binding proteins involved in actin-cytoskeleton rearrangement.PH domains have diverse functions, but in general are involved in targeting proteins to the appropriate cellular location or in the interaction with a binding partner. They share little sequence conservation, but all have a common fold, which is electrostatically polarized. Less than 10% of PH domains bind phosphoinositide phosphates (PIPs) with high affinity and specificity. PH domains are distinguished from other PIP-binding domains by their specific high-affinity binding to PIPs with two vicinal phosphate groups: PtdIns(3,4)P2, PtdIns(4,5)P2 or PtdIns(3,4,5)P3 which results in targeting some PH domain proteins to the plasma membrane []. A few display strong specificity in lipid binding. Any specificity is usually determined by loop regions or insertions in the N terminus of the domain, which are not conserved across all PH domains. PH domains are found in cellular signaling proteins such as serine/threonine kinase, tyrosine kinases, regulators of G-proteins, endocytotic GTPases, adaptors, as well as cytoskeletal associated molecules and in lipid associated enzymes.
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Publication
17562854 | J:125017
First Author: Smith FM
Year: 2007
Journal: Mol Cell Biol
Title: Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life.
Volume: 27
Issue: 16
Pages: 5871-86
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Publication
20396999 | J:162811
First Author: Ungaro P
Year: 2010
Journal: Diabetologia
Title: Hepatocyte nuclear factor (HNF)-4alpha-driven epigenetic silencing of the human PED gene.
Volume: 53
Issue: 7
Pages: 1482-92
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Publication
23190452 | J:211541
First Author: Desbuquois B
Year: 2013
Journal: FEBS J
Title: Regulation of insulin and type 1 insulin-like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteins.
Volume: 280
Issue: 3
Pages: 794-816
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Publication
28114323 | J:303454
First Author: Ishikawa A
Year: 2017
Journal: PLoS One
Title: Identification of a Putative Quantitative Trait Gene for Resistance to Obesity in Mice Using Transcriptome Analysis and Causal Inference Tests.
Volume: 12
Issue: 1
Pages: e0170652
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Protein
S4R2K5
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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