| Type |
Details |
Score |
| Publication |
| First Author: |
Luo M |
| Year: |
2015 |
| Journal: |
PLoS Genet |
| Title: |
Polycomb protein SCML2 associates with USP7 and counteracts histone H2A ubiquitination in the XY chromatin during male meiosis. |
| Volume: |
11 |
| Issue: |
1 |
| Pages: |
e1004954 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xu B |
| Year: |
2011 |
| Journal: |
PLoS One |
| Title: |
Replication stress induces micronuclei comprising of aggregated DNA double-strand breaks. |
| Volume: |
6 |
| Issue: |
4 |
| Pages: |
e18618 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bassing CH |
| Year: |
2008 |
| Journal: |
Blood |
| Title: |
Aberrant V(D)J recombination is not required for rapid development of H2ax/p53-deficient thymic lymphomas with clonal translocations. |
| Volume: |
111 |
| Issue: |
4 |
| Pages: |
2163-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zha S |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks. |
| Volume: |
469 |
| Issue: |
7329 |
| Pages: |
250-4 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yen WF |
| Year: |
2017 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
BRCT-domain protein BRIT1 influences class switch recombination. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Muñoz MC |
| Year: |
2014 |
| Journal: |
Nucleic Acids Res |
| Title: |
An RNF168 fragment defective for focal accumulation at DNA damage is proficient for inhibition of homologous recombination in BRCA1 deficient cells. |
| Volume: |
42 |
| Issue: |
12 |
| Pages: |
7720-33 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bhargava R |
| Year: |
2017 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Contribution of canonical nonhomologous end joining to chromosomal rearrangements is enhanced by ATM kinase deficiency. |
| Volume: |
114 |
| Issue: |
4 |
| Pages: |
728-733 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shi YQ |
| Year: |
2013 |
| Journal: |
Gene |
| Title: |
SYCP3-like X-linked 2 is expressed in meiotic germ cells and interacts with synaptonemal complex central element protein 2 and histone acetyltransferase TIP60. |
| Volume: |
527 |
| Issue: |
1 |
| Pages: |
352-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Song Y |
| Year: |
2023 |
| Journal: |
Life Sci Alliance |
| Title: |
Loss of circSRY reduces γH2AX level in germ cells and impairs mouse spermatogenesis. |
| Volume: |
6 |
| Issue: |
2 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
West MH |
| Year: |
1980 |
| Journal: |
Biochemistry |
| Title: |
Histone 2A, a heteromorphous family of eight protein species. |
| Volume: |
19 |
| Issue: |
14 |
| Pages: |
3238-45 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ward IM |
| Year: |
2003 |
| Journal: |
J Biol Chem |
| Title: |
Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX. |
| Volume: |
278 |
| Issue: |
22 |
| Pages: |
19579-82 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Riballo E |
| Year: |
2004 |
| Journal: |
Mol Cell |
| Title: |
A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. |
| Volume: |
16 |
| Issue: |
5 |
| Pages: |
715-24 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Xie A |
| Year: |
2004 |
| Journal: |
Mol Cell |
| Title: |
Control of sister chromatid recombination by histone H2AX. |
| Volume: |
16 |
| Issue: |
6 |
| Pages: |
1017-25 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Turner JM |
| Year: |
2005 |
| Journal: |
Nat Genet |
| Title: |
Silencing of unsynapsed meiotic chromosomes in the mouse. |
| Volume: |
37 |
| Issue: |
1 |
| Pages: |
41-7 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
143
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rybanska-Spaeder I |
| Year: |
2014 |
| Journal: |
PLoS One |
| Title: |
53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition. |
| Volume: |
9 |
| Issue: |
9 |
| Pages: |
e108731 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kato Y |
| Year: |
2015 |
| Journal: |
Hum Mol Genet |
| Title: |
FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis. |
| Volume: |
24 |
| Issue: |
18 |
| Pages: |
5234-49 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cloutier JM |
| Year: |
2016 |
| Journal: |
Chromosoma |
| Title: |
Mammalian meiotic silencing exhibits sexually dimorphic features. |
| Volume: |
125 |
| Issue: |
2 |
| Pages: |
215-26 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Singh N |
| Year: |
2012 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1. |
| Volume: |
109 |
| Issue: |
36 |
| Pages: |
14381-6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adamson B |
| Year: |
2012 |
| Journal: |
Nat Cell Biol |
| Title: |
A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. |
| Volume: |
14 |
| Issue: |
3 |
| Pages: |
318-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ismail IH |
| Year: |
2012 |
| Journal: |
Nucleic Acids Res |
| Title: |
CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage. |
| Volume: |
40 |
| Issue: |
12 |
| Pages: |
5497-510 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gawecka JE |
| Year: |
2013 |
| Journal: |
PLoS One |
| Title: |
Mouse zygotes respond to severe sperm DNA damage by delaying paternal DNA replication and embryonic development. |
| Volume: |
8 |
| Issue: |
2 |
| Pages: |
e56385 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fayer S |
| Year: |
2016 |
| Journal: |
Mamm Genome |
| Title: |
Robertsonian translocations modify genomic distribution of γH2AFX and H3.3 in mouse germ cells. |
| Volume: |
27 |
| Issue: |
5-6 |
| Pages: |
225-36 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu T |
| Year: |
2014 |
| Journal: |
Cell Stem Cell |
| Title: |
Histone variant H2A.X deposition pattern serves as a functional epigenetic mark for distinguishing the developmental potentials of iPSCs. |
| Volume: |
15 |
| Issue: |
3 |
| Pages: |
281-294 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Western blot |
| Annotation Date: |
2013-04-15 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:5474212 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
Testis |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5910047 |
| Assay Type: |
Western blot |
| Annotation Date: |
2017-09-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360422 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5910513 |
| Age: |
embryonic day 1.0 |
| Image: |
5 |
|
| Specimen Label: |
Control |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5910047 |
| Assay Type: |
Western blot |
| Annotation Date: |
2017-09-27 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360422 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:5910513 |
| Age: |
embryonic day 1.0 |
| Image: |
5 |
|
| Specimen Label: |
Bcas2mNull |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6383727 |
| Assay Type: |
Western blot |
| Annotation Date: |
2020-01-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716821 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:6383806 |
| Age: |
embryonic day 13.5 |
| Image: |
2 |
|
| Specimen Label: |
WT |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6383727 |
| Assay Type: |
Western blot |
| Annotation Date: |
2020-01-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716821 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:6383806 |
| Age: |
embryonic day 13.5 |
| Image: |
2 |
|
| Specimen Label: |
Pol mu -/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6383805 |
| Assay Type: |
Western blot |
| Annotation Date: |
2020-01-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716821 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:6383807 |
| Age: |
embryonic day 13.5 |
| Image: |
2 |
|
| Specimen Label: |
WT |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6383805 |
| Assay Type: |
Western blot |
| Annotation Date: |
2020-01-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1716821 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:6383807 |
| Age: |
embryonic day 13.5 |
| Image: |
2 |
|
| Specimen Label: |
Pol mu -/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-03-03 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7439832 |
| Age: |
postnatal adult |
| Image: |
5 |
|
| Specimen Label: |
+/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Western blot |
| Annotation Date: |
2023-03-03 |
| Strength: |
Absent |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7439832 |
| Age: |
postnatal adult |
| Image: |
5 |
|
| Specimen Label: |
-/- |
| Detected: |
false |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7541438 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-10-23 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3570528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7541451 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
GV |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7541438 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-10-23 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3575528 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7541451 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
MII |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7541438 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-10-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360411 |
|
| Stage: |
TS01 |
| Assay Id: |
MGI:7541451 |
| Age: |
embryonic day 0.5 |
|
|
| Specimen Label: |
Z |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7541438 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-10-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:360422 |
|
| Stage: |
TS02 |
| Assay Id: |
MGI:7541451 |
| Age: |
embryonic day 1.0 |
|
|
| Specimen Label: |
2-cell |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7610603 |
| Assay Type: |
Western blot |
| Annotation Date: |
2024-03-08 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:1797228 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7610664 |
| Age: |
postnatal adult |
|
|
| Specimen Label: |
WCE |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2012-02-15 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3570525 |
| Pattern: |
Not Specified |
| Stage: |
TS25 |
| Assay Id: |
MGI:5306038 |
| Age: |
embryonic day 17.5 |
|
|
| Specimen Label: |
5B +/- |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2012-02-15 |
| Strength: |
Strong |
| Sex: |
Female |
| Emaps: |
EMAPS:3570525 |
| Pattern: |
Not Specified |
| Stage: |
TS25 |
| Assay Id: |
MGI:5306038 |
| Age: |
embryonic day 17.5 |
|
| Note: |
Thgere is a 5-fold-larger area of expression in this mutant. |
| Specimen Label: |
5B -/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3839363 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-02-18 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3570528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5749218 |
| Age: |
postnatal |
| Image: |
4A |
|
| Specimen Label: |
4A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3839363 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-02-18 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3570528 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5749218 |
| Age: |
postnatal |
| Image: |
4B |
| Note: |
The number of positive foci has increased in this mutant oocyte. |
| Specimen Label: |
4B |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3839363 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-02-18 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3570527 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:5749218 |
| Age: |
postnatal day 0 |
| Image: |
S2 WT gH2AX Leptonema |
|
| Specimen Label: |
S2 WT gH2AX Leptonema |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3839363 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-02-18 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3570527 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:5749218 |
| Age: |
postnatal day 0 |
| Image: |
S2 WT gH2AX Zygonema |
|
| Specimen Label: |
S2 WT gH2AX Zygonema |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3839363 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-02-18 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3570527 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:5749218 |
| Age: |
postnatal day 0 |
| Image: |
S2 WT gH2AX Pachynema |
|
| Specimen Label: |
S2 WT gH2AX Pachynema |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3839363 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-02-18 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3570527 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:5749218 |
| Age: |
postnatal day 0 |
| Image: |
S2 Mutant gH2AX Leptonema |
| Note: |
Expression in this mutant is the same as in wild-type embryos. |
| Specimen Label: |
S2 Mutant gH2AX Leptonema |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3839363 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-02-18 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3570527 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:5749218 |
| Age: |
postnatal day 0 |
| Image: |
S2 Mutant gH2AX Zygonema |
| Note: |
Expression in this mutant is the same as in wild-type embryos. |
| Specimen Label: |
S2 Mutant gH2AX Zygonema |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3839363 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2016-02-18 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:3570527 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:5749218 |
| Age: |
postnatal day 0 |
| Image: |
S2 Mutant gH2AX Pachynema |
| Note: |
Expression in this mutant is the same as in wild-type embryos. |
| Specimen Label: |
S2 Mutant gH2AX Pachynema |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-15 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3570728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5474115 |
| Age: |
postnatal |
|
|
| Specimen Label: |
3A top, top merge |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2013-04-15 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3570728 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:5474116 |
| Age: |
postnatal |
|
|
| Specimen Label: |
3A bottom, bottom merge |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5629373 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-04-13 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3570728 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:5629426 |
| Age: |
postnatal |
|
| Note: |
Expression is in the nucleus. |
| Specimen Label: |
3B zygotene |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5629373 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-04-13 |
| Strength: |
Present |
| Sex: |
Male |
| Emaps: |
EMAPS:3570728 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:5629426 |
| Age: |
postnatal |
|
| Note: |
Expression is in the sex bodies. |
| Specimen Label: |
3B pachytene |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:1059702 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2018-12-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270422 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:6267487 |
| Age: |
embryonic day 14.5 |
|
|
| Specimen Label: |
Table S1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3584853 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-08-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760628 |
| Pattern: |
Regionally restricted |
| Stage: |
TS28 |
| Assay Id: |
MGI:3585394 |
| Age: |
postnatal day 6 |
|
| Note: |
Expression was detected in olfactory receptor neurons. |
| Specimen Label: |
CNS |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2683248 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2004-01-07 |
| Strength: |
Absent |
| Sex: |
Female |
| Emaps: |
EMAPS:1796521 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:2683253 |
| Age: |
embryonic day 13.5 |
| Image: |
4B, 13.5 dpc |
|
| Specimen Label: |
4B, 13.5 dpc |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2683248 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2004-01-07 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796522 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:2683253 |
| Age: |
embryonic day 14.5 |
| Image: |
4B, 14.5 dpc |
| Note: |
Staining in germ cells was first detected at 14.5 dpc. |
| Specimen Label: |
4B, 14.5 dpc |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:2683248 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2004-01-07 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796523 |
| Pattern: |
Widespread |
| Stage: |
TS23 |
| Assay Id: |
MGI:2683253 |
| Age: |
embryonic day 15.5 |
| Image: |
4B, 15.5 dpc |
| Note: |
Expression in germ cells throughout the gonad, in both cortex and medulla. |
| Specimen Label: |
4B, 15.5 dpc |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3839363 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2009-04-20 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796526 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:3840561 |
| Age: |
embryonic day 18.5 |
| Image: |
S9C |
|
| Specimen Label: |
S9C |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3839363 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2009-04-20 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796526 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:3840561 |
| Age: |
embryonic day 18.5 |
| Image: |
S9D |
| Note: |
Distribution was similar to wild type. |
| Specimen Label: |
S9D |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3839363 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2009-04-20 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796526 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:3840561 |
| Age: |
embryonic day 18.5 |
| Image: |
S9E |
|
| Specimen Label: |
S9E |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3839363 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2009-04-20 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796526 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:3840561 |
| Age: |
embryonic day 18.5 |
| Image: |
S9F |
| Note: |
Distribution was similar to wild type. |
| Specimen Label: |
S9F |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-04-25 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796523 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:7466386 |
| Age: |
embryonic day 15.5 |
|
| Note: |
In XX gonads germ cells are in an advanced stage of meiosis. |
| Specimen Label: |
1D XX Wt - upper |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6358696 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-05-20 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796524 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:7640176 |
| Age: |
embryonic day 16.5 |
|
| Note: |
Expression was detected in meiotic germ cells. |
| Specimen Label: |
3E Eed |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6358696 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-05-20 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796524 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:7640176 |
| Age: |
embryonic day 16.5 |
|
| Note: |
Expression was detected in meiotic germ cells in the mutant at similar levels to wild type. |
| Specimen Label: |
3E Eed |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6358696 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-05-20 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796524 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:7640176 |
| Age: |
embryonic day 16.5 |
|
| Note: |
Expression was detected in meiotic germ cells. |
| Specimen Label: |
S2 Eed |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6358696 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-05-20 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796524 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:7640176 |
| Age: |
embryonic day 16.5 |
|
| Note: |
Expression was detected in meiotic germ cells. |
| Specimen Label: |
S2 Eed |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6358696 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-05-20 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796524 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:7640176 |
| Age: |
embryonic day 16.5 |
|
| Note: |
Expression was detected in meiotic germ cells in the mutant at similar levels to wild type. |
| Specimen Label: |
S2 Eed |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7855910 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-01-29 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796523 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:7856604 |
| Age: |
embryonic day 15.5 |
| Image: |
1A O15 |
|
| Specimen Label: |
1A O15 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7855910 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-01-29 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1796523 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:7856604 |
| Age: |
embryonic day 15.5 |
| Image: |
S2 O15 |
|
| Specimen Label: |
S2 O15 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6430453 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737322 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7481339 |
| Age: |
embryonic day 14.5 |
| Image: |
4E |
| Note: |
Not coexpressed with Six2. |
| Specimen Label: |
4E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6430453 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-05-15 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1737322 |
| Pattern: |
Not Specified |
| Stage: |
TS22 |
| Assay Id: |
MGI:7481339 |
| Age: |
embryonic day 14.5 |
| Image: |
4G |
| Note: |
Not coexpressed with Six2. |
| Specimen Label: |
4G |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-03-20 |
| Strength: |
Ambiguous |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284220 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:6400789 |
| Age: |
embryonic day 11.5 |
| Image: |
4E E11 mutant |
|
| Specimen Label: |
4E E11 mutant |
|
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-03-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284220 |
| Pattern: |
Not Specified |
| Stage: |
TS20 |
| Assay Id: |
MGI:6400789 |
| Age: |
embryonic day 12.5 |
| Image: |
4D mut |
| Note: |
The majority of H2ax-immunopositive cells in the mutant pallium were pyknotic, and 93.2% were also cleaved-Casp3-positive. |
| Specimen Label: |
4D mut |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-03-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284220 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:6400789 |
| Age: |
embryonic day 12.5 |
| Image: |
4E E12 mutant |
| Note: |
74.7% of H2ax-immunopositive cells in the mutant pallium were also Trp53-positive. |
| Specimen Label: |
4E E12 mutant |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-03-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284220 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:6400789 |
| Age: |
embryonic day 12.5 |
| Image: |
4F left |
| Note: |
46.3% of H2ax-immunopositive cells in the mutant pallium were also Pax6-immunopositive radial glial cells. |
| Specimen Label: |
4F left |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-03-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284220 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:6400789 |
| Age: |
embryonic day 12.5 |
| Image: |
4F middle |
| Note: |
H2ax-immunopositive cells in the mutant pallium were not Tbr2-immunopositive intermediate progenitor cells. |
| Specimen Label: |
4F middle |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-03-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284220 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:6400789 |
| Age: |
embryonic day 12.5 |
| Image: |
4F right |
| Note: |
Virtually no H2ax-immunopositive cells in the mutant pallium were Rbfox3-immunopositive neurons (5.1%). |
| Specimen Label: |
4F right |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-03-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284220 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:6400789 |
| Age: |
embryonic day 11.5 |
| Image: |
4E E11 control |
|
| Specimen Label: |
4E E11 control |
| Detected: |
false |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-03-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284220 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:6400789 |
| Age: |
embryonic day 12.5 |
| Image: |
4E E12 control |
|
| Specimen Label: |
4E E12 control |
| Detected: |
false |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-03-20 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284220 |
|
| Stage: |
TS20 |
| Assay Id: |
MGI:6400789 |
| Age: |
embryonic day 12.5 |
| Image: |
4D ctrl |
|
| Specimen Label: |
4D ctrl |
| Detected: |
false |
| Specimen Num: |
1 |
|
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•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5305847 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-03-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284220 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:6400789 |
| Age: |
embryonic day 12.5 |
| Image: |
6A |
| Note: |
38.5% of H2ax-immunopositive cells were also EdU+, similar to the total percentage of EdU+ cells in the mutant pallium. |
| Specimen Label: |
6A |
| Detected: |
true |
| Specimen Num: |
10 |
|
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•
•
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•
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