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Search results 101 to 115 out of 115 for Harbi1

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0.027s

Type

Details

Score

Gene

121399122 | LOC121399122

Type:	gene
Organism:	frog, African clawed

•

Gene

121399421 | LOC121399421

Type:	gene
Organism:	frog, African clawed

•

Gene

121401340 | LOC121401340

Type:	gene
Organism:	frog, African clawed

•

Gene

137496691 | LOC137496691

Type:	gene
Organism:	zebrafish

•

Protein

Q8BR93-2

Organism:	Mus musculus/domesticus
Length:	244
Fragment?:	false

•

Protein

Q8BR93-3

Organism:	Mus musculus/domesticus
Length:	246
Fragment?:	false

•

Protein Coding Gene

MGI:1196429 | Atg13

Type:	protein_coding_gene
Organism:	mouse, laboratory

•

Protein Domain

IPR026103 | HARBI1_animal

Type:

Family

Description:

This entry represents the Harbinger transposase-derived proteins mostly from animals. Proteins in this family may have nuclease activity, but do not appear to have transposase activity [, ].Harbinger DNA transposons have been identified in protists, plants, insects,worms, and vertebrates. However, mammals do not have Harbinger transposons. In human, no recognisable members of Harbinger transposase superfamily are found. Instead, a widely expressed HARBI1 gene encoding a 350-amino acid protein derived from a Harbinger transposase has been identified []. The HARBI1 protein is conserved in humans, rats, mice, cows, pigs, chickens, frogs and various bony fish []. Conserved motifs, which are expected to be catalytic centres of nuclease/ligase reactions necessary for transpositions, found in the Harbinger transposases, are also well preserved in the HARBI1 proteins []. It was also proposed that these hypothetical HARBI1 nucleases are also characterised by a strong DNA-target specificity [].

•

Publication

18339812 | -

First Author:	Sinzelle L
Year:	2008
Journal:	Proc Natl Acad Sci U S A
Title:	Transposition of a reconstructed Harbinger element in human cells and functional homology with two transposon-derived cellular genes.
Volume:	105
Issue:	12
Pages:	4715-20

•

Publication

2463832 | -

First Author:	Hergenhahn HG
Year:	1988
Journal:	Biochem J
Title:	Purification and characterization of an alpha 2-macroglobulin-like proteinase inhibitor from plasma of the crayfish Pacifastacus leniusculus.
Volume:	255
Issue:	3
Pages:	801-6

•

Publication

26642436 | -

First Author:	Liang SC
Year:	2015
Journal:	PLoS Genet
Title:	Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2.
Volume:	11
Issue:	12
Pages:	e1005660

•

Protein Domain

IPR045249 | HARBI1-like

Type:	Family
Description:	This entry represents a group of Harbinger transposase-derived proteins, including HARBI1 from animals and ALP1/ALP1L from Arabidopsis. Proteins in this family may have nuclease activity, but do not appear to have transposase activity [, ]. ALP1 is a domesticated Harbinger-related nuclease that interacts genetically with several PcG and trxG components and antagonizes PcG silencing [, ].

•

Protein Domain

IPR027806 | HARBI1_dom

Type:	Domain
Description:	This domain is found in proteins that are related to and are probably endonucleases of the DDE superfamily. Proteins containing this domain include the putative nuclease HARBI1. HARBI1 is a transposase-derived protein that may have nuclease activity potential. It does not have transposase activity [, ].

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

•

Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

•

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