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Search results 101 to 200 out of 644 for Hbb-b1

0.022s
Type Details Score
Publication
First Author: Dasgupta T
Year: 2006
Journal: Free Radic Biol Med
Title: Protective effect of arginine on oxidative stress in transgenic sickle mouse models.
Volume: 41
Issue: 12
Pages: 1771-80
Publication
First Author: Romero JR
Year: 2002
Journal: Blood
Title: Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity.
Volume: 99
Issue: 4
Pages: 1103-8
Publication
First Author: Vincent L
Year: 2013
Journal: Blood
Title: Mast cell activation contributes to sickle cell pathobiology and pain in mice.
Volume: 122
Issue: 11
Pages: 1853-62
Publication
First Author: Collinson JM
Year: 2003
Journal: Dev Biol
Title: The roles of Pax6 in the cornea, retina, and olfactory epithelium of the developing mouse embryo.
Volume: 255
Issue: 2
Pages: 303-12
Publication
First Author: Vallelian F
Year: 2022
Journal: Cell Death Differ
Title: Heme-stress activated NRF2 skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages in hemolytic anemia.
Volume: 29
Issue: 8
Pages: 1450-1465
Publication
First Author: Hanson MS
Year: 2013
Journal: Am J Physiol Heart Circ Physiol
Title: A novel hemoglobin-binding peptide reduces cell-free hemoglobin in murine hemolytic anemia.
Volume: 304
Issue: 2
Pages: H328-36
Publication
First Author: Takabayashi S
Year: 2005
Journal: Exp Anim
Title: A mutant mouse with severe anemia and skin abnormalities controlled by a new allele of the flaky skin (fsn) locus.
Volume: 54
Issue: 4
Pages: 339-47
Publication
First Author: Sun K
Year: 2015
Journal: Blood
Title: Elevated adenosine signaling via adenosine A2B receptor induces normal and sickle erythrocyte sphingosine kinase 1 activity.
Volume: 125
Issue: 10
Pages: 1643-52
Publication
First Author: Ning C
Year: 2014
Journal: FASEB J
Title: Excess adenosine A2B receptor signaling contributes to priapism through HIF-1α mediated reduction of PDE5 gene expression.
Volume: 28
Issue: 6
Pages: 2725-35
Publication
First Author: Mi T
Year: 2008
Journal: J Clin Invest
Title: Excess adenosine in murine penile erectile tissues contributes to priapism via A2B adenosine receptor signaling.
Volume: 118
Issue: 4
Pages: 1491-501
Publication
First Author: Wen J
Year: 2010
Journal: FASEB J
Title: Increased adenosine contributes to penile fibrosis, a dangerous feature of priapism, via A2B adenosine receptor signaling.
Volume: 24
Issue: 3
Pages: 740-9
Publication
First Author: Mason KD
Year: 2007
Journal: Cell
Title: Programmed anuclear cell death delimits platelet life span.
Volume: 128
Issue: 6
Pages: 1173-86
Publication
First Author: Walsh CP
Year: 1999
Journal: Genes Dev
Title: Cytosine methylation and mammalian development.
Volume: 13
Issue: 1
Pages: 26-34
Publication
First Author: Perkins AC
Year: 1995
Journal: Nature
Title: Lethal beta-thalassaemia in mice lacking the erythroid CACCC-transcription factor EKLF.
Volume: 375
Issue: 6529
Pages: 318-22
Publication
First Author: Huang S
Year: 2024
Journal: Nat Commun
Title: Mutations in linker-2 of KLF1 impair expression of membrane transporters and cytoskeletal proteins causing hemolysis.
Volume: 15
Issue: 1
Pages: 7019
Publication
First Author: Lagoda G
Year: 2014
Journal: FASEB J
Title: Sustained nitric oxide (NO)-releasing compound reverses dysregulated NO signal transduction in priapism.
Volume: 28
Issue: 1
Pages: 76-84
Publication
First Author: Champion HC
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Phosphodiesterase-5A dysregulation in penile erectile tissue is a mechanism of priapism.
Volume: 102
Issue: 5
Pages: 1661-6
Publication
First Author: Wood KC
Year: 2005
Journal: FASEB J
Title: Endothelial cell NADPH oxidase mediates the cerebral microvascular dysfunction in sickle cell transgenic mice.
Volume: 19
Issue: 8
Pages: 989-91
Allele
Name: hemoglobin, beta adult major chain; targeted mutation 1, University of North Carolina
Allele Type: Targeted
Attribute String: Null/knockout
Strain
Attribute String: targeted mutation, mutant stock
Strain
Attribute String: congenic, mutant strain, targeted mutation
Allele
Name: hemoglobin, beta adult minor chain; targeted mutation 1, University of North Carolina
Allele Type: Targeted
Attribute String: Null/knockout
Publication
First Author: Nishino T
Year: 2006
Journal: Br J Haematol
Title: Effects of human gamma-globin in murine beta-thalassaemia.
Volume: 134
Issue: 1
Pages: 100-8
Publication
First Author: Xu C
Year: 2020
Journal: Immunity
Title: The Gut Microbiome Regulates Psychological-Stress-Induced Inflammation.
Volume: 53
Issue: 2
Pages: 417-428.e4
Publication
First Author: Wood KC
Year: 2004
Journal: Am J Physiol Heart Circ Physiol
Title: Endothelial cell P-selectin mediates a proinflammatory and prothrombogenic phenotype in cerebral venules of sickle cell transgenic mice.
Volume: 286
Issue: 5
Pages: H1608-14
Publication
First Author: Zhang D
Year: 2015
Journal: Nature
Title: Neutrophil ageing is regulated by the microbiome.
Volume: 525
Issue: 7570
Pages: 528-32
Publication
First Author: Hidalgo A
Year: 2009
Journal: Nat Med
Title: Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury.
Volume: 15
Issue: 4
Pages: 384-91
Publication
First Author: Robert-Moreno A
Year: 2007
Journal: Leukemia
Title: The notch pathway positively regulates programmed cell death during erythroid differentiation.
Volume: 21
Issue: 7
Pages: 1496-503
Publication
First Author: Nuez B
Year: 1995
Journal: Nature
Title: Defective haematopoiesis in fetal liver resulting from inactivation of the EKLF gene.
Volume: 375
Issue: 6529
Pages: 316-8
Publication  
First Author: Porcu S
Year: 2005
Journal: Gene
Title: beta-Minor globin gene expression is preferentially reduced in EKLF Knock-Out mice.
Volume: 351
Pages: 11-7
Publication
First Author: Lin CS
Year: 1996
Journal: Genes Dev
Title: Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis.
Volume: 10
Issue: 2
Pages: 154-64
Publication
First Author: Lee R
Year: 2001
Journal: Blood
Title: Erythropoietin (Epo) and EpoR expression and 2 waves of erythropoiesis.
Volume: 98
Issue: 5
Pages: 1408-15
Publication
First Author: Yoon D
Year: 2006
Journal: J Biol Chem
Title: Hypoxia-inducible factor-1 deficiency results in dysregulated erythropoiesis signaling and iron homeostasis in mouse development.
Volume: 281
Issue: 35
Pages: 25703-11
Publication
First Author: Rampon C
Year: 2003
Journal: Int J Dev Biol
Title: Multilineage hematopoietic progenitor activity generated autonomously in the mouse yolk sac: analysis using angiogenesis-defective embryos.
Volume: 47
Issue: 4
Pages: 273-80
Allele  
Name: hemoglobin beta chain complex; s2
Allele Type: Chemically induced (ENU)
Publication
First Author: Lewis SE
Year: 1985
Journal: Proc Natl Acad Sci U S A
Title: A mutation in the beta-globin gene detected in the progeny of a female mouse treated with ethylnitrosourea.
Volume: 82
Issue: 17
Pages: 5829-31
Publication
First Author: Bender MA
Year: 2012
Journal: Blood
Title: The hypersensitive sites of the murine β-globin locus control region act independently to affect nuclear localization and transcriptional elongation.
Volume: 119
Issue: 16
Pages: 3820-7
Publication
First Author: Siatecka M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor.
Volume: 107
Issue: 34
Pages: 15151-6
Publication
First Author: Novelli EM
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Vascular TSP1-CD47 signaling promotes sickle cell-associated arterial vasculopathy and pulmonary hypertension in mice.
Volume: 316
Issue: 6
Pages: L1150-L1164
Publication
First Author: Kieran MW
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor.
Volume: 93
Issue: 17
Pages: 9126-31
Publication
First Author: Yoon MJ
Year: 2008
Journal: Mol Cell Biol
Title: Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches.
Volume: 28
Issue: 15
Pages: 4794-804
Publication
First Author: Chen W
Year: 2011
Journal: Am J Pathol
Title: Protein phosphatase 2A catalytic subunit α (PP2Acα) maintains survival of committed erythroid cells in fetal liver erythropoiesis through the STAT5 pathway.
Volume: 178
Issue: 5
Pages: 2333-43
Publication
First Author: Eiymo Mwa Mpollo MS
Year: 2016
Journal: J Clin Invest
Title: Placenta growth factor augments airway hyperresponsiveness via leukotrienes and IL-13.
Volume: 126
Issue: 2
Pages: 571-84
Allele
Name: hemoglobin beta chain complex; targeted mutation 2, University of North Carolina
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
Strain
Attribute String: targeted mutation, mutant stock
Publication
First Author: Lewis J
Year: 1998
Journal: Blood
Title: A common human beta globin splicing mutation modeled in mice.
Volume: 91
Issue: 6
Pages: 2152-6
Publication
First Author: Xie SY
Year: 2007
Journal: Hum Mol Genet
Title: Restoration of the balanced alpha/beta-globin gene expression in beta654-thalassemia mice using combined RNAi and antisense RNA approach.
Volume: 16
Issue: 21
Pages: 2616-25
Publication  
First Author: Bahal R
Year: 2016
Journal: Nat Commun
Title: In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery.
Volume: 7
Pages: 13304
Publication
First Author: Svasti S
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice.
Volume: 106
Issue: 4
Pages: 1205-10
Publication
First Author: Chaichompoo P
Year: 2022
Journal: Sci Rep
Title: Increased autophagy leads to decreased apoptosis during β-thalassaemic mouse and patient erythropoiesis.
Volume: 12
Issue: 1
Pages: 18628
Publication
First Author: Hatada S
Year: 2011
Journal: Exp Hematol
Title: Therapeutic benefits in thalassemic mice transplanted with long-term-cultured bone marrow cells.
Volume: 39
Issue: 3
Pages: 375-83, 383.e1-4
Publication  
First Author: Han G
Year: 2022
Journal: Redox Biol
Title: Nrf2 expands the intracellular pool of the chaperone AHSP in a cellular model of β-thalassemia.
Volume: 50
Pages: 102239
Publication
First Author: Li J
Year: 2014
Journal: J Clin Invest
Title: Neutrophil AKT2 regulates heterotypic cell-cell interactions during vascular inflammation.
Volume: 124
Issue: 4
Pages: 1483-96
Publication
First Author: Chen G
Year: 2016
Journal: Exp Hematol
Title: Targeting Mac-1-mediated leukocyte-RBC interactions uncouples the benefits for acute vaso-occlusion and chronic organ damage.
Volume: 44
Issue: 10
Pages: 940-6
Publication
First Author: Pasricha SR
Year: 2017
Journal: Nat Commun
Title: Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.
Volume: 8
Issue: 1
Pages: 403
Publication
First Author: Keleku-Lukwete N
Year: 2019
Journal: Blood Adv
Title: Nrf2 activation in myeloid cells and endothelial cells differentially mitigates sickle cell disease pathology in mice.
Volume: 3
Issue: 8
Pages: 1285-1297
Publication
First Author: Boulais PE
Year: 2018
Journal: Immunity
Title: The Majority of CD45- Ter119- CD31- Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors.
Volume: 49
Issue: 4
Pages: 627-639.e6
Publication
First Author: Ghanem LR
Year: 2015
Journal: Mol Cell Biol
Title: The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed Derivative Pcbp1 Are Independently Essential to Mouse Development.
Volume: 36
Issue: 2
Pages: 304-19
Publication
First Author: Wang H
Year: 2019
Journal: Physiol Rep
Title: Sickle cell disease up-regulates vasopressin, aquaporin 2, urea transporter A1, Na-K-Cl cotransporter 2, and epithelial Na channels in the mouse kidney medulla despite compromising urinary concentration ability.
Volume: 7
Issue: 8
Pages: e14066
Publication
First Author: Zhang Y
Year: 2011
Journal: Nat Med
Title: Detrimental effects of adenosine signaling in sickle cell disease.
Volume: 17
Issue: 1
Pages: 79-86
Publication
First Author: Lopez RA
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Multiple hematopoietic defects and delayed globin switching in Ikaros null mice.
Volume: 99
Issue: 2
Pages: 602-7
Publication
First Author: Xu J
Year: 2011
Journal: Science
Title: Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.
Volume: 334
Issue: 6058
Pages: 993-6
Publication
First Author: Sankaran VG
Year: 2009
Journal: Nature
Title: Developmental and species-divergent globin switching are driven by BCL11A.
Volume: 460
Issue: 7259
Pages: 1093-7
Publication
First Author: Gudmundsdottir B
Year: 2018
Journal: Cell Rep
Title: POGZ Is Required for Silencing Mouse Embryonic β-like Hemoglobin and Human Fetal Hemoglobin Expression.
Volume: 23
Issue: 11
Pages: 3236-3248
Publication
First Author: Johnson KD
Year: 2015
Journal: Sci Adv
Title: Cis-regulatory mechanisms governing stem and progenitor cell transitions.
Volume: 1
Issue: 8
Pages: e1500503
Publication
First Author: Elorza A
Year: 2008
Journal: J Biol Chem
Title: UCP2 modulates cell proliferation through the MAPK/ERK pathway during erythropoiesis and has no effect on heme biosynthesis.
Volume: 283
Issue: 45
Pages: 30461-70
Publication
First Author: Kaneko H
Year: 2012
Journal: J Biol Chem
Title: N- and C-terminal transactivation domains of GATA1 protein coordinate hematopoietic program.
Volume: 287
Issue: 25
Pages: 21439-49
Publication
First Author: Borges L
Year: 2012
Journal: Blood
Title: A critical role for endoglin in the emergence of blood during embryonic development.
Volume: 119
Issue: 23
Pages: 5417-28
Publication
First Author: Szuber N
Year: 2008
Journal: Exp Hematol
Title: Alternative treatment paradigm for thalassemia using iron chelators.
Volume: 36
Issue: 7
Pages: 773-85
Publication
First Author: Huang J
Year: 2004
Journal: Nucleic Acids Res
Title: Lsh, an epigenetic guardian of repetitive elements.
Volume: 32
Issue: 17
Pages: 5019-28
Publication
First Author: McConnell SC
Year: 2011
Journal: Mol Cell Biol
Title: Human globin knock-in mice complete fetal-to-adult hemoglobin switching in postnatal development.
Volume: 31
Issue: 4
Pages: 876-83
Publication
First Author: Huo Y
Year: 2009
Journal: J Biol Chem
Title: Humanized Mouse Model of Cooley's Anemia.
Volume: 284
Issue: 8
Pages: 4889-96
Publication
First Author: Sparkenbaugh EM
Year: 2016
Journal: Blood
Title: Thrombin-independent contribution of tissue factor to inflammation and cardiac hypertrophy in a mouse model of sickle cell disease.
Volume: 127
Issue: 10
Pages: 1371-3
Publication
First Author: Nakajima O
Year: 2006
Journal: Genes Cells
Title: Transgenic rescue of erythroid 5-aminolevulinate synthase-deficient mice results in the formation of ring sideroblasts and siderocytes.
Volume: 11
Issue: 6
Pages: 685-700
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Dumitriu B
Year: 2010
Journal: PLoS One
Title: Sox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditions.
Volume: 5
Issue: 8
Pages: e12088
Publication
First Author: Regan CP
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Erk5 null mice display multiple extraembryonic vascular and embryonic cardiovascular defects.
Volume: 99
Issue: 14
Pages: 9248-53
Publication
First Author: Suzuki Y
Year: 2002
Journal: Biochem Biophys Res Commun
Title: Model mice for Presbyterian hemoglobinopathy (Asn(beta108)-->Lys) confer hemolytic anemia with altered oxygen affinity and instability of Hb.
Volume: 295
Issue: 4
Pages: 869-76
Publication
First Author: Shirasawa T
Year: 2003
Journal: J Biol Chem
Title: Oxygen affinity of hemoglobin regulates O2 consumption, metabolism, and physical activity.
Volume: 278
Issue: 7
Pages: 5035-43
Publication
First Author: Martin R
Year: 2004
Journal: Development
Title: SCL interacts with VEGF to suppress apoptosis at the onset of hematopoiesis.
Volume: 131
Issue: 3
Pages: 693-702
Publication
First Author: Xi C
Year: 2023
Journal: Blood
Title: Nrf2 sensitizes ferroptosis through l-2-hydroxyglutarate-mediated chromatin modifications in sickle cell disease.
Volume: 142
Issue: 4
Pages: 382-396
Publication
First Author: Zhang F
Year: 2023
Journal: Nature
Title: An extra-erythrocyte role of haemoglobin body in chondrocyte hypoxia adaption.
Volume: 622
Issue: 7984
Pages: 834-841
Publication
First Author: Bultman SJ
Year: 2005
Journal: Genes Dev
Title: A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development.
Volume: 19
Issue: 23
Pages: 2849-61
Publication
First Author: Song SH
Year: 2010
Journal: Blood
Title: Multiple functions of Ldb1 required for beta-globin activation during erythroid differentiation.
Volume: 116
Issue: 13
Pages: 2356-64
Publication
First Author: Coulpier F
Year: 2009
Journal: Glia
Title: Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers.
Volume: 57
Issue: 13
Pages: 1450-7
Publication
First Author: Ashe A
Year: 2008
Journal: Genome Biol
Title: A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development.
Volume: 9
Issue: 12
Pages: R182
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Fiering S
Year: 1995
Journal: Genes Dev
Title: Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.
Volume: 9
Issue: 18
Pages: 2203-13
Publication
First Author: Keng VW
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Homeobox gene Hex is essential for onset of mouse embryonic liver development and differentiation of the monocyte lineage.
Volume: 276
Issue: 3
Pages: 1155-61
Publication
First Author: Ramos P
Year: 2013
Journal: Nat Med
Title: Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia.
Volume: 19
Issue: 4
Pages: 437-45
Publication
First Author: Chantrathammachart P
Year: 2012
Journal: Blood
Title: Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease.
Volume: 120
Issue: 3
Pages: 636-46
Strain
Attribute String: mutant stock, targeted mutation, transgenic
Strain
Attribute String: targeted mutation, transgenic, mutant stock
Publication
First Author: Yalamanoglu A
Year: 2018
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Depletion of haptoglobin and hemopexin promote hemoglobin-mediated lipoprotein oxidation in sickle cell disease.
Volume: 315
Issue: 5
Pages: L765-L774
Publication  
First Author: Sargur Madabushi S
Year: 2022
Journal: Front Oncol
Title: Development and characterization of a preclinical total marrow irradiation conditioning-based bone marrow transplant model for sickle cell disease.
Volume: 12
Pages: 969429
Publication  
First Author: Cui MH
Year: 2022
Journal: Transl Res
Title: Corrected cerebral blood flow and reduced cerebral inflammation in berk sickle mice with higher fetal hemoglobin.
Volume: 244
Pages: 75-87
Publication
First Author: Archer DR
Year: 2008
Journal: J Nutr
Title: C-reactive protein and interleukin-6 are decreased in transgenic sickle cell mice fed a high protein diet.
Volume: 138
Issue: 6
Pages: 1148-52
Publication
First Author: Stivala S
Year: 2022
Journal: J Thromb Haemost
Title: Dietary alpha-linolenic acid reduces platelet activation and collagen-mediated cell adhesion in sickle cell disease mice.
Volume: 20
Issue: 2
Pages: 375-386
Publication
First Author: Kiefmann R
Year: 2008
Journal: Blood
Title: Red blood cells induce hypoxic lung inflammation.
Volume: 111
Issue: 10
Pages: 5205-14
Publication  
First Author: Peslak SA
Year: 2023
Journal: Mol Ther Nucleic Acids
Title: Forced enhancer-promoter rewiring to alter gene expression in animal models.
Volume: 31
Pages: 452-465