| Type |
Details |
Score |
| GXD Expression |
| Probe: |
MGI:3506448 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-02-07 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:2874723 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:5539458 |
| Age: |
embryonic day 15.5 |
| Image: |
GUDMAP:5782 |
|
| Specimen Label: |
GUDMAP:5782 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3506448 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2005-01-03 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1757721 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:3512432 |
| Age: |
embryonic day 13.5 |
| Image: |
1 |
|
| Specimen Label: |
1 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3506448 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-02-07 |
| Strength: |
Absent |
| Sex: |
Female |
| Emaps: |
EMAPS:2850023 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:5539458 |
| Age: |
embryonic day 15.5 |
| Image: |
GUDMAP:5782 |
|
| Specimen Label: |
GUDMAP:5782 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1689428 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691480 |
| Age: |
postnatal adult |
| Image: |
JAX_1798455 |
|
| Specimen Label: |
JAX_1798455 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3506448 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-02-07 |
| Strength: |
Absent |
| Sex: |
Female |
| Emaps: |
EMAPS:1796223 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:5539458 |
| Age: |
embryonic day 15.5 |
| Image: |
GUDMAP:5782 |
|
| Specimen Label: |
GUDMAP:5782 |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
|
| Assay Type: |
In situ reporter (knock in) |
| Annotation Date: |
2021-04-16 |
| Strength: |
Present |
| Sex: |
Female |
| Emaps: |
EMAPS:1881228 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:6691480 |
| Age: |
postnatal adult |
| Image: |
JAX_1798449 |
|
| Specimen Label: |
JAX_1798449 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
492
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhang L |
| Year: |
2024 |
| Journal: |
Front Genet |
| Title: |
Integrative transcriptomic profiling of ncRNAs and mRNAs in developing mouse lens. |
| Volume: |
15 |
|
| Pages: |
1405715 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cavalheiro GR |
| Year: |
2017 |
| Journal: |
Dev Biol |
| Title: |
N-myc regulates growth and fiber cell differentiation in lens development. |
| Volume: |
429 |
| Issue: |
1 |
| Pages: |
105-117 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yoshimura S |
| Year: |
2024 |
| Journal: |
Nat Commun |
| Title: |
Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions. |
| Volume: |
15 |
| Issue: |
1 |
| Pages: |
3330 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Medina-Martinez O |
| Year: |
2009 |
| Journal: |
Dev Dyn |
| Title: |
Pitx3 controls multiple aspects of lens development. |
| Volume: |
238 |
| Issue: |
9 |
| Pages: |
2193-201 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Keegan CE |
| Year: |
2005 |
| Journal: |
Hum Mol Genet |
| Title: |
Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator. |
| Volume: |
14 |
| Issue: |
1 |
| Pages: |
113-23 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chang B |
| Year: |
2005 |
| Journal: |
Vis Neurosci |
| Title: |
Mouse models of ocular diseases. |
| Volume: |
22 |
| Issue: |
5 |
| Pages: |
587-93 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yokoyama S |
| Year: |
2009 |
| Journal: |
Dev Cell |
| Title: |
A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. |
| Volume: |
17 |
| Issue: |
6 |
| Pages: |
836-48 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Dickinson ME |
| Year: |
2016 |
| Journal: |
Nature |
| Title: |
High-throughput discovery of novel developmental phenotypes. |
| Volume: |
537 |
| Issue: |
7621 |
| Pages: |
508-514 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Jackson Laboratory |
| Year: |
2012 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by The Jackson Laboratory |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gray PA |
| Year: |
2004 |
| Journal: |
Science |
| Title: |
Mouse brain organization revealed through direct genome-scale TF expression analysis. |
| Volume: |
306 |
| Issue: |
5705 |
| Pages: |
2255-7 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Koscielny G |
| Year: |
2014 |
| Journal: |
Nucleic Acids Res |
| Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
| Volume: |
42 |
| Issue: |
Database issue |
| Pages: |
D802-9 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wellcome Trust Sanger Institute |
| Year: |
2009 |
| Journal: |
MGI Direct Data Submission |
| Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GUDMAP Consortium |
| Year: |
2004 |
| Journal: |
www.gudmap.org |
| Title: |
GUDMAP: the GenitoUrinary Development Molecular Anatomy Project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
| Year: |
2014 |
| Journal: |
Database Release |
| Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2014 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
|
| Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Carninci P |
| Year: |
2005 |
| Journal: |
Science |
| Title: |
The transcriptional landscape of the mammalian genome. |
| Volume: |
309 |
| Issue: |
5740 |
| Pages: |
1559-63 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Adams DJ |
| Year: |
2024 |
| Journal: |
Nature |
| Title: |
Genetic determinants of micronucleus formation in vivo. |
| Volume: |
627 |
| Issue: |
8002 |
| Pages: |
130-136 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Skarnes WC |
| Year: |
2011 |
| Journal: |
Nature |
| Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
| Volume: |
474 |
| Issue: |
7351 |
| Pages: |
337-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Cyagen Biosciences Inc. |
| Year: |
2022 |
|
| Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
| Year: |
2011 |
|
| Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
GOA curators |
| Year: |
2016 |
|
| Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
The Gene Ontology Consortium |
| Year: |
2010 |
|
| Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Diez-Roux G |
| Year: |
2011 |
| Journal: |
PLoS Biol |
| Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
e1000582 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
MGI Genome Annotation Group and UniGene Staff |
| Year: |
2015 |
| Journal: |
Database Download |
| Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
| Year: |
2000 |
| Journal: |
Database Release |
| Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Allen Institute for Brain Science |
| Year: |
2004 |
| Journal: |
Allen Institute |
| Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
| Year: |
2010 |
| Journal: |
Database Download |
| Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Group |
| Year: |
2003 |
| Journal: |
Database Procedure |
| Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bairoch A |
| Year: |
1999 |
| Journal: |
Database Release |
| Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics |
| Year: |
2010 |
| Journal: |
Database Release |
| Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2005 |
|
| Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mouse Genome Informatics Scientific Curators |
| Year: |
2009 |
| Journal: |
Database Download |
| Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE12415 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| HT Experiment |
| Series Id: |
GSE22362 |
| Experiment Type: |
transcription profiling by array |
| Study Type: |
WT vs. Mutant |
| Source: |
ArrayExpress |
|
•
•
•
•
•
|
| Allele |
| Name: |
heat shock transcription factor 4; targeted mutation 1, Nahid F Mivechi |
| Allele Type: |
Targeted |
| Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Hsf4/Hsf4 |
| Background: |
involves: 129S2/SvPas * C57BL/6 |
| Zygosity: |
hm |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Allele |
| Name: |
transgene insertion N7, Suraj P Bhat |
| Allele Type: |
Transgenic |
| Attribute String: |
Inserted expressed sequence, Reporter |
|
•
•
•
•
•
|
| Strain |
| Attribute String: |
mutant strain, transgenic, coisogenic |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Bhat SP |
| Year: |
2019 |
| Journal: |
J Biol Chem |
| Title: |
Transcriptional profiling of single fiber cells in a transgenic paradigm of an inherited childhood cataract reveals absence of molecular heterogeneity. |
| Volume: |
294 |
| Issue: |
37 |
| Pages: |
13530-13544 |
|
•
•
•
•
•
|
| Genotype |
| Symbol: |
Tg(Hsf4/EGFP)N7Spbh/? |
| Background: |
C57BL/6-Tg(Hsf4/EGFP)N7Spbh |
| Zygosity: |
ot |
| Has Mutant Allele: |
true |
|
•
•
•
•
•
|
| Publication |
| First Author: |
McMillan DR |
| Year: |
2002 |
| Journal: |
Mol Cell Biol |
| Title: |
Heat shock transcription factor 2 is not essential for embryonic development, fertility, or adult cognitive and psychomotor function in mice. |
| Volume: |
22 |
| Issue: |
22 |
| Pages: |
8005-14 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fujimoto M |
| Year: |
2010 |
| Journal: |
Mol Biol Cell |
| Title: |
A novel mouse HSF3 has the potential to activate nonclassical heat-shock genes during heat shock. |
| Volume: |
21 |
| Issue: |
1 |
| Pages: |
106-16 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shaohua H |
| Year: |
2023 |
| Journal: |
J Cell Mol Med |
| Title: |
Aquaporin 5 maintains lens transparency by regulating the lysosomal pathway using circRNA. |
| Volume: |
27 |
| Issue: |
6 |
| Pages: |
803-818 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Taiwo O |
| Year: |
2013 |
| Journal: |
Epigenetics |
| Title: |
DNA methylation analysis of murine hematopoietic side population cells during aging. |
| Volume: |
8 |
| Issue: |
10 |
| Pages: |
1114-22 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Whitson JA |
| Year: |
2017 |
| Journal: |
Free Radic Biol Med |
| Title: |
Proteomic analysis of the glutathione-deficient LEGSKO mouse lens reveals activation of EMT signaling, loss of lens specific markers, and changes in stress response proteins. |
| Volume: |
113 |
|
| Pages: |
84-96 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
He S |
| Year: |
2010 |
| Journal: |
Epigenetics Chromatin |
| Title: |
Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation. |
| Volume: |
3 |
| Issue: |
1 |
| Pages: |
21 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Sun J |
| Year: |
2015 |
| Journal: |
Mol Vis |
| Title: |
Chromatin features, RNA polymerase II and the comparative expression of lens genes encoding crystallins, transcription factors, and autophagy mediators. |
| Volume: |
21 |
|
| Pages: |
955-73 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gerhard DS |
| Year: |
2004 |
| Journal: |
Genome Res |
| Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
| Volume: |
14 |
| Issue: |
10B |
| Pages: |
2121-7 |
|
•
•
•
•
•
|