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Search results 101 to 200 out of 200 for Hsph1

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Type Details Score
GXD Expression
GXD Expression
     
Probe: MGI:7461958
Assay Type: Western blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:7462573
Age: embryonic day 14.5
Specimen Label: 14 Liver
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:7461958
Assay Type: Western blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610519
Stage: TS19
Assay Id: MGI:7462573
Age: embryonic day 11.5
Specimen Label: 11 Heart
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:7461958
Assay Type: Western blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:7462573
Age: embryonic day 14.5
Specimen Label: 14 Heart
Detected: true
Specimen Num: 8
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•
GXD Expression
GXD Expression
     
Probe: MGI:7461958
Assay Type: Western blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287419
Stage: TS19
Assay Id: MGI:7462573
Age: embryonic day 11.5
Specimen Label: 11 Intestine
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:7461958
Assay Type: Western blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3287422
Stage: TS22
Assay Id: MGI:7462573
Age: embryonic day 14.5
Specimen Label: 14 Intestine
Detected: true
Specimen Num: 10
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•
GXD Expression
GXD Expression
     
Probe: MGI:7461958
Assay Type: Western blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640519
Stage: TS19
Assay Id: MGI:7462573
Age: embryonic day 11.5
Specimen Label: 11 Limb
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:7461958
Assay Type: Western blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640522
Stage: TS22
Assay Id: MGI:7462573
Age: embryonic day 14.5
Specimen Label: 14 Limb
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:7461958
Assay Type: Western blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Stage: TS19
Assay Id: MGI:7462573
Age: embryonic day 11.5
Specimen Label: 11 Residue
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
     
Probe: MGI:7461958
Assay Type: Western blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:7462573
Age: embryonic day 14.5
Specimen Label: 14 Residue
Detected: true
Specimen Num: 14
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GXD Expression
GXD Expression
     
Probe: MGI:7462001
Assay Type: Northern blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603913
Stage: TS13
Assay Id: MGI:7462658
Age: embryonic day 8.5
Specimen Label: 8
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7462001
Assay Type: Northern blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:7462658
Age: embryonic day 10.5
Specimen Label: 10
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
     
Probe: MGI:7462001
Assay Type: Northern blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:7462658
Age: embryonic day 12.5
Specimen Label: 12
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
     
Probe: MGI:7462001
Assay Type: Northern blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:7462658
Age: embryonic day 14.5
Specimen Label: 14
Detected: true
Specimen Num: 4
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•
GXD Expression
GXD Expression
     
Probe: MGI:7462001
Assay Type: Northern blot
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:7462658
Age: embryonic day 17.5
Specimen Label: 17
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1611815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7564545
Age: embryonic day 9.5
Note: Expression was detected in numerous cells located in the dorsal part of the first two branchial arches.
Specimen Label: 1E
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1614815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7564545
Age: embryonic day 9.5
Note: Expression was detected in neural epithelium of the rhombencephalon.
Specimen Label: 1F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1626215
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7564545
Age: embryonic day 9.5
Note: Expression was detected in dental lamina.
Specimen Label: 1E
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1626217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7564545
Age: embryonic day 10.5
Note: Expression was detected in the dental lamina.
Specimen Label: 2E
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7461958
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7462666
Age: embryonic day 11.5
Note: Expressed in the cytoplasm and nuclei of neuroepithelial cells.
Specimen Label: 4A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7461958
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691019
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7462666
Age: embryonic day 11.5
Note: Expressed in the cytoplasm and nuclei of neuroepithelial cells.
Specimen Label: 4B
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:7461958
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1666822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7462666
Age: embryonic day 14.5
Specimen Label: 5A
Detected: true
Specimen Num: 3
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:7461958
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1666822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7462666
Age: embryonic day 14.5
Specimen Label: 5D
Detected: true
Specimen Num: 5
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•
GXD Expression
GXD Expression
 
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3596115
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7564545
Age: embryonic day 9.5
Note: Expression was detected in mesectoderm.
Specimen Label: 1D
Detected: true
Specimen Num: 1
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3596115
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7564545
Age: embryonic day 9.5
Note: Expression was detected in mesectoderm.
Specimen Label: 1E
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3596115
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7564546
Age: embryonic day 9.5
Note: Expression was detected within mesectodermal cells. TUNEL-positive cells were detected in the same area (shown in adjacent pane).
Specimen Label: 3A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3596117
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7564545
Age: embryonic day 10.5
Note: Compared with E9.5, the expression at E10.5 has progressed in a more distal (ventral) direction. Expression was detected in dorsal mesectodermal cells and in epiblast.
Specimen Label: 2F
Detected: true
Specimen Num: 5
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1647017
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7564545
Age: embryonic day 10.5
Note: Expression was detected in the neural epithelium.
Specimen Label: 2F
Detected: true
Specimen Num: 5
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7564545
Age: embryonic day 9.5
Note: Expression was detected in the epiblast.
Specimen Label: 1F
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
   
Probe: MGI:7461958
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1767822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7462666
Age: embryonic day 14.5
Specimen Label: 5D
Detected: true
Specimen Num: 5
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7461958
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1684622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7462666
Age: embryonic day 14.5
Specimen Label: 5A
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7461958
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-17
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1684622
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7462666
Age: embryonic day 14.5
Specimen Label: 5B
Detected: true
Specimen Num: 4
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7461958
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3261821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7462666
Age: embryonic day 13.5
Specimen Label: 6B
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
 
Probe: MGI:7461958
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3261821
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:7462666
Age: embryonic day 13.5
Note: Expressed in condensed cells and condensed bodies.
Specimen Label: 6D
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1638215
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7564545
Age: embryonic day 9.5
Specimen Label: 1E
Detected: true
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
 
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1638217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7564545
Age: embryonic day 10.5
Note: Expression was detected in more distal mesectodermal cells, as compared with E9.5, within the mandibular bud.
Specimen Label: 2E
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1627215
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7564545
Age: embryonic day 9.5
Note: Expression was detected in numerous cells located in the dorsal part of the first two branchial arches.
Specimen Label: 1E
Detected: true
Specimen Num: 2
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•
•
GXD Expression
GXD Expression
   
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7564545
Age: embryonic day 9.5
Specimen Label: 1D
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609815
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7564545
Age: embryonic day 9.5
Note: Expression was detected in mesenchymal cells ventral to the otic vesicle.
Specimen Label: 1F
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1638815
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:7564545
Age: embryonic day 9.5
Specimen Label: 1E
Detected: true
Specimen Num: 2
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•
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•
GXD Expression
GXD Expression
   
Probe: MGI:7564537
Assay Type: Immunohistochemistry
Annotation Date: 2023-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1638817
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7564545
Age: embryonic day 10.5
Specimen Label: 2E
Detected: true
Specimen Num: 4
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Publication
12749852 | J:172890
First Author: Saito Y
Year: 2003
Journal: Exp Cell Res
Title: Identification of alpha-tubulin as an hsp105alpha-binding protein by the yeast two-hybrid system.
Volume: 286
Issue: 2
Pages: 233-40
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Publication
10378145 | J:55460
First Author: Evrard L
Year: 1999
Journal: J Craniofac Genet Dev Biol
Title: Cytochemical identification of HSP110 during early mouse facial development.
Volume: 19
Issue: 1
Pages: 24-32
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Publication
17085013 | J:125118
First Author: Mix E
Year: 2006
Journal: J Autoimmun
Title: 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitor Atorvastatin mediated effects depend on the activation status of target cells in PLP-EAE.
Volume: 27
Issue: 4
Pages: 251-65
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Publication
25088258 | J:217560
First Author: Saito Y
Year: 2014
Journal: Exp Cell Res
Title: Nmi interacts with Hsp105β and enhances the Hsp105β-mediated Hsp70 expression.
Volume: 327
Issue: 1
Pages: 163-70
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Publication
9431456 | J:45236
First Author: Hatayama T
Year: 1997
Journal: Cell Struct Funct
Title: Characteristic expression of high molecular mass heat shock protein HSP105 during mouse embryo development.
Volume: 22
Issue: 5
Pages: 517-25
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Publication
16764683 | J:112182
First Author: Gashegu J
Year: 2006
Journal: Orthod Craniofac Res
Title: Correlation of Hsp110 expression with caspase-3 and -9 during apoptosis induced by in vivo embryonic exposition to retinoic acid or irradiation in early mouse craniofacial development.
Volume: 9
Issue: 2
Pages: 84-92
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Publication
14644449 | J:86751
First Author: Yamagishi N
Year: 2003
Journal: FEBS Lett
Title: Hsp105 but not Hsp70 family proteins suppress the aggregation of heat-denatured protein in the presence of ADP.
Volume: 555
Issue: 2
Pages: 390-6
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Publication
24717441 | J:210436
First Author: Olszak T
Year: 2014
Journal: Nature
Title: Protective mucosal immunity mediated by epithelial CD1d and IL-10.
Volume: 509
Issue: 7501
Pages: 497-502
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Publication
9344682 | J:41735
First Author: Hunt CR
Year: 1997
Journal: Genomics
Title: Assignment of the mouse Hsp25 and Hsp105 genes to the distal region of chromosome 5 by linkage analysis.
Volume: 45
Issue: 2
Pages: 462-3
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Publication
17298173 | J:141590
First Author: Kornmann B
Year: 2007
Journal: PLoS Biol
Title: System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock.
Volume: 5
Issue: 2
Pages: e34
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Publication
19171884 | J:144475
First Author: Wang J
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS.
Volume: 106
Issue: 5
Pages: 1392-7
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Publication
21487003 | J:180915
First Author: Held T
Year: 2011
Journal: Reproduction
Title: Heat-shock protein HSPA4 is required for progression of spermatogenesis.
Volume: 142
Issue: 1
Pages: 133-44
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Publication
36385105 | J:331267
First Author: de Thonel A
Year: 2022
Journal: Nat Commun
Title: CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder.
Volume: 13
Issue: 1
Pages: 7002
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Publication
23980576 | J:231873
First Author: Mohamed BA
Year: 2014
Journal: Am J Respir Cell Mol Biol
Title: Respiratory distress and early neonatal lethality in Hspa4l/Hspa4 double-mutant mice.
Volume: 50
Issue: 4
Pages: 817-24
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Publication
10464095 | J:57234
First Author: Lee CK
Year: 1999
Journal: Science
Title: Gene expression profile of aging and its retardation by caloric restriction.
Volume: 285
Issue: 5432
Pages: 1390-3
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Publication
- | J:46439
     
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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16141072 | J:99680
First Author: Carninci P
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21677750 | J:173534
First Author: Skarnes WC
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Volume: 474
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First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
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First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
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Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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First Author: UniProt-GOA
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Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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First Author: GOA curators
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Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
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12466851 | J:80000
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First Author: The Gene Ontology Consortium
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Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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First Author: Mouse Genome Informatics Scientific Curators
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First Author: MGI Genome Annotation Group and UniGene Staff
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First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
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Title: Annotation inferences using phylogenetic trees
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First Author: Allen Institute for Brain Science
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Journal: Allen Institute
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First Author: Mouse Genome Informatics Scientific Curators
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Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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First Author: Mouse Genome Informatics
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Journal: Database Release
Title: Protein Ontology Association Load.
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First Author: Mouse Genome Informatics Scientific Curators
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Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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25573990 | -
First Author: Zappasodi R
Year: 2015
Journal: Blood
Title: HSPH1 inhibition downregulates Bcl-6 and c-Myc and hampers the growth of human aggressive B-cell non-Hodgkin lymphoma.
Volume: 125
Issue: 11
Pages: 1768-71
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First Author: Kai M
Year: 2003
Journal: Oncol Rep
Title: Heat shock protein 105 is overexpressed in a variety of human tumors.
Volume: 10
Issue: 6
Pages: 1777-82
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19476517 | -
First Author: Park HS
Year: 2009
Journal: J Cutan Pathol
Title: Expression of heat shock protein 105 and 70 in malignant melanoma and benign melanocytic nevi.
Volume: 36
Issue: 5
Pages: 511-6
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Publication
20542028 | -
First Author: Yamagishi N
Year: 2010
Journal: Exp Cell Res
Title: Hsp105 reduces the protein aggregation and cytotoxicity by expanded-polyglutamine proteins through the induction of Hsp70.
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Issue: 15
Pages: 2424-33
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Publication
23737532 | -
First Author: Mattoo RU
Year: 2013
Journal: J Biol Chem
Title: Hsp110 is a bona fide chaperone using ATP to unfold stable misfolded polypeptides and reciprocally collaborate with Hsp70 to solubilize protein aggregates.
Volume: 288
Issue: 29
Pages: 21399-411
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Protein Domain
IPR042053 | HSPH1_NBD
Type: Domain
Description: Human HSPH1 (also known as heat shock 105kDa/110kDa protein 1, HSP105; HSP105A; HSP105B) suppresses the aggregation of denatured proteins caused by heat shock in vitro, and may substitute for HSP70 family proteins to suppress the aggregation of denatured proteins in cells under severe stress []. It reduces the protein aggregation and cytotoxicity associated with Polyglutamine (PolyQ) diseases, including Huntington's disease, which are a group of inherited neurodegenerative disorders sharing the characteristic feature of having insoluble protein aggregates in neurons []. The expression of HSPH1 is elevated in various malignant tumors, including malignant melanoma, and there is a direct correlation between HSPH1 expression and B-cell non-Hodgkin lymphomas (B-NHLs) aggressiveness and proliferation [, , ]. HSPH1 belongs to the 105/110kDa heat shock protein (HSP105/110) subfamily of the HSP70-like family. HSP105/110s are believed to function generally as co-chaperones of HSP70 chaperones, acting as nucleotide exchange factors (NEFs), to remove ADP from their HSP70 chaperone partners during the ATP hydrolysis cycle. HSP70 chaperones assist in protein folding and assembly, and can direct incompetent 'client' proteins towards degradation. Like HSP70 chaperones, HSP105/110s have an N-terminal nucleotide-binding domain (NBD) and a C-terminal substrate-binding domain (SBD) [].This entry represents the N-terminal nucleotide-binding domain of HSPH1.
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Protein
Q61699
Organism: Mus musculus/domesticus
Length: 858  
Fragment?: false
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Publication
15770419 | -
First Author: Mayer MP
Year: 2005
Journal: Cell Mol Life Sci
Title: Hsp70 chaperones: cellular functions and molecular mechanism.
Volume: 62
Issue: 6
Pages: 670-84
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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