Type |
Details |
Score |
Publication |
First Author: |
Martins LM |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice. |
Volume: |
24 |
Issue: |
22 |
Pages: |
9848-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martins LM |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif. |
Volume: |
277 |
Issue: |
1 |
Pages: |
439-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ulett GC |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
Mechanisms of group B streptococcal-induced apoptosis of murine macrophages. |
Volume: |
175 |
Issue: |
4 |
Pages: |
2555-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kieper N |
Year: |
2010 |
Journal: |
Exp Cell Res |
Title: |
Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1. |
Volume: |
316 |
Issue: |
7 |
Pages: |
1213-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim JB |
Year: |
2013 |
Journal: |
J Biol Chem |
Title: |
Identification of a novel anti-apoptotic E3 ubiquitin ligase that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC, HtrA2, and ARTS. |
Volume: |
288 |
Issue: |
17 |
Pages: |
12014-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nunes M |
Year: |
2001 |
Journal: |
Mech Dev |
Title: |
NSPc1, a novel mammalian Polycomb gene, is expressed in neural crest-derived structures of the peripheral nervous system. |
Volume: |
102 |
Issue: |
1-2 |
Pages: |
219-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rathke-Hartlieb S |
Year: |
2000 |
Journal: |
FEBS Lett |
Title: |
Elevated expression of membrane type 1 metalloproteinase (MT1-MMP) in reactive astrocytes following neurodegeneration in mouse central nervous system. |
Volume: |
481 |
Issue: |
3 |
Pages: |
227-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jones JM |
Year: |
1993 |
Journal: |
Genomics |
Title: |
mnd2: a new mouse model of inherited motor neuron disease. |
Volume: |
16 |
Issue: |
3 |
Pages: |
669-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu ML |
Year: |
2009 |
Journal: |
J Cell Sci |
Title: |
Omi is a mammalian heat-shock protein that selectively binds and detoxifies oligomeric amyloid-beta. |
Volume: |
122 |
Issue: |
Pt 11 |
Pages: |
1917-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dannenberg JH |
Year: |
2004 |
Journal: |
Genes Dev |
Title: |
Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130. |
Volume: |
18 |
Issue: |
23 |
Pages: |
2952-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamauchi S |
Year: |
2014 |
Journal: |
J Cell Biol |
Title: |
p53-mediated activation of the mitochondrial protease HtrA2/Omi prevents cell invasion. |
Volume: |
204 |
Issue: |
7 |
Pages: |
1191-207 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jang W |
Year: |
1999 |
Journal: |
Genome Res |
Title: |
Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13. |
Volume: |
9 |
Issue: |
1 |
Pages: |
53-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo Y |
Year: |
2004 |
Journal: |
J Biol Chem |
Title: |
Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death. |
Volume: |
279 |
Issue: |
23 |
Pages: |
24813-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hu Q |
Year: |
2012 |
Journal: |
Sci Signal |
Title: |
The protease Omi cleaves the mitogen-activated protein kinase kinase MEK1 to inhibit microglial activation. |
Volume: |
5 |
Issue: |
238 |
Pages: |
ra61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barrow LL |
Year: |
1994 |
Journal: |
Genomics |
Title: |
Conserved linkage of early growth response 4, annexin 4, and transforming growth factor alpha on mouse chromosome 6. |
Volume: |
19 |
Issue: |
2 |
Pages: |
388-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weber JS |
Year: |
1998 |
Journal: |
Genomics |
Title: |
High-resolution genetic, physical, and transcript map of the mnd2 region of mouse chromosome 6. |
Volume: |
54 |
Issue: |
1 |
Pages: |
107-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Andree M |
Year: |
2014 |
Journal: |
EMBO J |
Title: |
BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella. |
Volume: |
33 |
Issue: |
19 |
Pages: |
2171-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Swaroop A |
Year: |
1994 |
Journal: |
Hum Mol Genet |
Title: |
Molecular characterization of a novel human gene, SEC13R, related to the yeast secretory pathway gene SEC13, and mapping to a conserved linkage group on human chromosome 3p24-p25 and mouse chromosome 6. |
Volume: |
3 |
Issue: |
8 |
Pages: |
1281-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Patel A |
Year: |
1995 |
Journal: |
Genomics |
Title: |
Mapping of the taurine transporter gene to mouse chromosome 6 and to the short arm of human chromosome 3. |
Volume: |
25 |
Issue: |
1 |
Pages: |
314-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hostager BS |
Year: |
2010 |
Journal: |
PLoS One |
Title: |
HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex. |
Volume: |
5 |
Issue: |
6 |
Pages: |
e11380 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shen T |
Year: |
2024 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Cardiac-specific deletion of heat shock protein 60 induces mitochondrial stress and disrupts heart development in mice. |
Volume: |
710 |
|
Pages: |
149883 |
|
•
•
•
•
•
|
Publication |
First Author: |
Soma S |
Year: |
2024 |
Journal: |
Stem Cells |
Title: |
O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. |
Volume: |
42 |
Issue: |
1 |
Pages: |
55-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mootha VK |
Year: |
2003 |
Journal: |
Cell |
Title: |
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. |
Volume: |
115 |
Issue: |
5 |
Pages: |
629-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pagliarini DJ |
Year: |
2008 |
Journal: |
Cell |
Title: |
A mitochondrial protein compendium elucidates complex I disease biology. |
Volume: |
134 |
Issue: |
1 |
Pages: |
112-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dickinson ME |
Year: |
2016 |
Journal: |
Nature |
Title: |
High-throughput discovery of novel developmental phenotypes. |
Volume: |
537 |
Issue: |
7621 |
Pages: |
508-514 |
|
•
•
•
•
•
|
Publication |
First Author: |
Koscielny G |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
Volume: |
42 |
Issue: |
Database issue |
Pages: |
D802-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
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|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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|
|
|
•
•
•
•
•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
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|
|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
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|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
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|
|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
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|
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
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•
|
HT Experiment |
Series Id: |
GSE13033 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Allele |
Name: |
HtrA serine peptidase 2; targeted mutation 1.2, Josephine Hoh |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang C |
Year: |
2019 |
Journal: |
Cell Death Dis |
Title: |
Inhibition of HtrA2 alleviated dextran sulfate sodium (DSS)-induced colitis by preventing necroptosis of intestinal epithelial cells. |
Volume: |
10 |
Issue: |
5 |
Pages: |
344 |
|
•
•
•
•
•
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DO Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
458
 |
Fragment?: |
false |
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•
•
•
•
|
Publication |
First Author: |
Sun Y |
Year: |
2017 |
Journal: |
Biochim Biophys Acta |
Title: |
MLF1 is a proapoptotic antagonist of HOP complex-mediated survival. |
Volume: |
1864 |
Issue: |
4 |
Pages: |
719-727 |
|
•
•
•
•
•
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Publication |
First Author: |
Wang X |
Year: |
2004 |
Journal: |
Neurobiol Dis |
Title: |
X-linked inhibitor of apoptosis (XIAP) protein protects against caspase activation and tissue loss after neonatal hypoxia-ischemia. |
Volume: |
16 |
Issue: |
1 |
Pages: |
179-89 |
|
•
•
•
•
•
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Publication |
First Author: |
Hsu PL |
Year: |
2016 |
Journal: |
Oncotarget |
Title: |
Matricellular protein CCN1 mediates doxorubicin-induced cardiomyopathy in mice. |
Volume: |
7 |
Issue: |
24 |
Pages: |
36698-36710 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zheng N |
Year: |
2025 |
Journal: |
Transl Psychiatry |
Title: |
Electrophysiology-based screening identifies neuronal HtrA serine peptidase 2 (HTRA2) as a synaptic plasticity regulator participating in tauopathy. |
Volume: |
15 |
Issue: |
1 |
Pages: |
5 |
|
•
•
•
•
•
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Publication |
First Author: |
Eroglu B |
Year: |
2022 |
Journal: |
Cell Mol Life Sci |
Title: |
Dusp26 phosphatase regulates mitochondrial respiration and oxidative stress and protects neuronal cell death. |
Volume: |
79 |
Issue: |
4 |
Pages: |
198 |
|
•
•
•
•
•
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Publication |
First Author: |
Gammie SC |
Year: |
2022 |
Journal: |
Sci Rep |
Title: |
Evaluation of animal model congruence to human depression based on large-scale gene expression patterns of the CNS. |
Volume: |
12 |
Issue: |
1 |
Pages: |
108 |
|
•
•
•
•
•
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Publication |
First Author: |
Ogando DG |
Year: |
2010 |
Journal: |
Mol Vis |
Title: |
Candidate genes for chromosomes 6 and 10 quantitative trait loci for age-related retinal degeneration in mice. |
Volume: |
16 |
|
Pages: |
1004-18 |
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•
•
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•
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