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Search results 101 to 200 out of 253 for Hus1

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Type Details Score
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_05
Specimen Label: euxassay_012664_05
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_06
Specimen Label: euxassay_012664_06
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_07
Specimen Label: euxassay_012664_07
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_08
Specimen Label: euxassay_012664_08
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_09
Specimen Label: euxassay_012664_09
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_10
Specimen Label: euxassay_012664_10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_11
Specimen Label: euxassay_012664_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_12
Specimen Label: euxassay_012664_12
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_13
Specimen Label: euxassay_012664_13
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_09
Specimen Label: euxassay_012664_09
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_10
Specimen Label: euxassay_012664_10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1690823
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_11
Specimen Label: euxassay_012664_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753923
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_09
Specimen Label: euxassay_012664_09
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753923
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_10
Specimen Label: euxassay_012664_10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1753923
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_11
Specimen Label: euxassay_012664_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_04
Specimen Label: euxassay_012664_04
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_05
Specimen Label: euxassay_012664_05
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_15
Specimen Label: euxassay_012664_15
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_16
Specimen Label: euxassay_012664_16
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_17
Specimen Label: euxassay_012664_17
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1756823
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_18
Specimen Label: euxassay_012664_18
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_09
Specimen Label: euxassay_012664_09
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_13
Specimen Label: euxassay_012664_13
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_14
Specimen Label: euxassay_012664_14
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4417220
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4825487
Age: embryonic day 14.5
Image: euxassay_012664_15
Specimen Label: euxassay_012664_15
Detected: true
Specimen Num: 14
Publication
First Author: Jiang K
Year: 2003
Journal: J Biol Chem
Title: Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345.
Volume: 278
Issue: 27
Pages: 25207-17
Publication
First Author: Cmarik JL
Year: 2000
Journal: Genomics
Title: cDNA cloning and mapping of mouse pleckstrin (Plek), a gene upregulated in transformation-resistant cells.
Volume: 66
Issue: 2
Pages: 204-12
Publication
First Author: Wallace MD
Year: 2014
Journal: Oncogene
Title: Role of DNA damage response pathways in preventing carcinogenesis caused by intrinsic replication stress.
Volume: 33
Issue: 28
Pages: 3688-95
Publication
First Author: Hang H
Year: 2002
Journal: Genomics
Title: Identification and characterization of a paralog of human cell cycle checkpoint gene HUS1.
Volume: 79
Issue: 4
Pages: 487-92
Protein
Organism: Mus musculus/domesticus
Length: 280  
Fragment?: false
Publication
First Author: Colgan J
Year: 2000
Journal: Genomics
Title: Isolation, characterization and targeted disruption of mouse ppia: cyclophilin A is not essential for mammalian cell viability.
Volume: 68
Issue: 2
Pages: 167-78
Publication      
First Author: Colgan JD
Year: 2000
Journal: MGI Direct Data Submission
Title: Isolation and characterization of mouse Ppia, the gene encoding Cyclophilin A
Publication  
First Author: Akagawa R
Year: 2021
Journal: Front Cell Dev Biol
Title: Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons.
Volume: 9
Pages: 753175
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
Publication      
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Protein Domain
Type: Family
Description: Hus1 is a component of the 9-1-1 cell-cycle checkpoint response complex (which consists of Rad9, Hus1, Rad1), a key complex in the coordination of DNA damage sensing, cell cycle progression and DNA repair pathways. In humans, the 9-1-1 complex is recruited to DNA lesions upon damage by the RAD17-replication factor C (RFC) clamp loader complex. It activates checkpoint response and acts as a sliding clamp platform on DNA for several proteins involved in DNA repair. The 9-1-1 complex is necessary for the recruitment of C12orf32/RHINO to sites of double-stranded breaks (DSB) occurring during the S phase [].
UniProt Feature
Begin: 1
Description: Checkpoint protein HUS1
Type: chain
End: 280
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: macaque, rhesus
Protein
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 300  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 276  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 276  
Fragment?: false
Gene
Type: gene
Organism: frog, African clawed
Publication
First Author: Wang X
Year: 2004
Journal: Nucleic Acids Res
Title: Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation.
Volume: 32
Issue: 2
Pages: 767-75
Allele  
Name: HUS1 checkpoint clamp component; wild type
Allele Type: Not Specified
Allele    
Name: HUS1 checkpoint clamp component B; wild type
Allele
Name: HUS1 checkpoint clamp component; targeted mutation 1, Philip Leder
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: HUS1 checkpoint clamp component; targeted mutation 1, Robert S Weiss
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
Allele
Name: HUS1 checkpoint clamp component; targeted mutation 1.1, Robert S Weiss
Allele Type: Targeted
Attribute String: Null/knockout
Allele
Name: HUS1 checkpoint clamp component; targeted mutation 2, Robert S Weiss
Allele Type: Targeted
Attribute String: Conditional ready, Hypomorph
Allele
Name: HUS1 checkpoint clamp component B; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele  
Name: HUS1 checkpoint clamp component; gene trap OST409102, Lexicon Genetics
Allele Type: Gene trapped
Allele
Name: HUS1 checkpoint clamp component; endonuclease-mediated mutation 1, GemPharmatech
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory