Type |
Details |
Score |
Publication |
First Author: |
Chung Y |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
A critical role of costimulation during intrathymic development of invariant NK T cells. |
Volume: |
180 |
Issue: |
4 |
Pages: |
2276-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pepper M |
Year: |
2011 |
Journal: |
Immunity |
Title: |
Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells. |
Volume: |
35 |
Issue: |
4 |
Pages: |
583-95 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Weinstein JS |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
B cells in T follicular helper cell development and function: separable roles in delivery of ICOS ligand and antigen. |
Volume: |
192 |
Issue: |
7 |
Pages: |
3166-79 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
322
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Maazi H |
Year: |
2015 |
Journal: |
Immunity |
Title: |
ICOS:ICOS-ligand interaction is required for type 2 innate lymphoid cell function, homeostasis, and induction of airway hyperreactivity. |
Volume: |
42 |
Issue: |
3 |
Pages: |
538-51 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
47 |
Description: |
ICOS ligand |
Type: |
chain |
End: |
322 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marczynska J |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
The role of metalloproteinase ADAM17 in regulating ICOS ligand-mediated humoral immune responses. |
Volume: |
193 |
Issue: |
6 |
Pages: |
2753-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Greenwald RJ |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
Cutting edge: inducible costimulator protein regulates both Th1 and Th2 responses to cutaneous leishmaniasis. |
Volume: |
168 |
Issue: |
3 |
Pages: |
991-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tada Y |
Year: |
2006 |
Journal: |
Clin Immunol |
Title: |
Role of inducible costimulator in the development of lupus in MRL/lpr mice. |
Volume: |
120 |
Issue: |
2 |
Pages: |
179-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dong C |
Year: |
2001 |
Journal: |
J Immunol |
Title: |
Cutting edge: critical role of inducible costimulator in germinal center reactions. |
Volume: |
166 |
Issue: |
6 |
Pages: |
3659-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stolberg VR |
Year: |
2005 |
Journal: |
Cell Immunol |
Title: |
Analysis of inducible costimulatory molecule participation during the induction and elicitation of granulomatous responses to mycobacterial and schistosomal antigens. |
Volume: |
237 |
Issue: |
1 |
Pages: |
45-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dong C |
Year: |
2003 |
Journal: |
J Autoimmun |
Title: |
Regulation of immune and autoimmune responses by ICOS. |
Volume: |
21 |
Issue: |
3 |
Pages: |
255-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kornete M |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
ICOS-dependent homeostasis and function of Foxp3+ regulatory T cells in islets of nonobese diabetic mice. |
Volume: |
188 |
Issue: |
3 |
Pages: |
1064-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li J |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Phosphatidylinositol 3-kinase-independent signaling pathways contribute to ICOS-mediated T cell costimulation in acute graft-versus-host disease in mice. |
Volume: |
191 |
Issue: |
1 |
Pages: |
200-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen H |
Year: |
2014 |
Journal: |
Cancer Immunol Res |
Title: |
CD4 T cells require ICOS-mediated PI3K signaling to increase T-Bet expression in the setting of anti-CTLA-4 therapy. |
Volume: |
2 |
Issue: |
2 |
Pages: |
167-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Scales HE |
Year: |
2004 |
Journal: |
Eur J Immunol |
Title: |
Effect of inducible costimulator blockade on the pathological and protective immune responses induced by the gastrointestinal helminth Trichinella spiralis. |
Volume: |
34 |
Issue: |
10 |
Pages: |
2854-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gigoux M |
Year: |
2009 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase. |
Volume: |
106 |
Issue: |
48 |
Pages: |
20371-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vidric M |
Year: |
2006 |
Journal: |
Infect Immun |
Title: |
Role for inducible costimulator in control of Salmonella enterica serovar Typhimurium infection in mice. |
Volume: |
74 |
Issue: |
2 |
Pages: |
1050-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Watanabe M |
Year: |
2005 |
Journal: |
J Immunol |
Title: |
ICOS-mediated costimulation on Th2 differentiation is achieved by the enhancement of IL-4 receptor-mediated signaling. |
Volume: |
174 |
Issue: |
4 |
Pages: |
1989-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hubbard VM |
Year: |
2005 |
Journal: |
Blood |
Title: |
Absence of inducible costimulator on alloreactive T cells reduces graft versus host disease and induces Th2 deviation. |
Volume: |
106 |
Issue: |
9 |
Pages: |
3285-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gotsman I |
Year: |
2006 |
Journal: |
Circulation |
Title: |
Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule. |
Volume: |
114 |
Issue: |
19 |
Pages: |
2047-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao X |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Anti-chlamydial Th17 responses are controlled by the inducible costimulator partially through phosphoinositide 3-kinase signaling. |
Volume: |
7 |
Issue: |
12 |
Pages: |
e52657 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kopf M |
Year: |
2000 |
Journal: |
J Exp Med |
Title: |
Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection. |
Volume: |
192 |
Issue: |
1 |
Pages: |
53-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Teichmann LL |
Year: |
2015 |
Journal: |
Immunity |
Title: |
Local triggering of the ICOS coreceptor by CD11c(+) myeloid cells drives organ inflammation in lupus. |
Volume: |
42 |
Issue: |
3 |
Pages: |
552-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu D |
Year: |
2007 |
Journal: |
Nature |
Title: |
Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA. |
Volume: |
450 |
Issue: |
7167 |
Pages: |
299-303 |
|
•
•
•
•
•
|
Publication |
First Author: |
Raineri D |
Year: |
2020 |
Journal: |
Commun Biol |
Title: |
Osteopontin binds ICOSL promoting tumor metastasis. |
Volume: |
3 |
Issue: |
1 |
Pages: |
615 |
|
•
•
•
•
•
|
Publication |
First Author: |
Suh WK |
Year: |
2004 |
Journal: |
J Immunol |
Title: |
The inducible costimulator plays the major costimulatory role in humoral immune responses in the absence of CD28. |
Volume: |
172 |
Issue: |
10 |
Pages: |
5917-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Villegas EN |
Year: |
2002 |
Journal: |
J Immunol |
Title: |
A role for inducible costimulator protein in the CD28- independent mechanism of resistance to Toxoplasma gondii. |
Volume: |
169 |
Issue: |
2 |
Pages: |
937-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao X |
Year: |
2013 |
Journal: |
Mol Med |
Title: |
Enhanced inducible costimulator ligand (ICOS-L) expression on dendritic cells in interleukin-10 deficiency and its impact on T-cell subsets in respiratory tract infection. |
Volume: |
19 |
Issue: |
1 |
Pages: |
346-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu Q |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
ICOS-expressing lymphocytes promote resolution of CD8-mediated lung injury in a mouse model of lung rejection. |
Volume: |
8 |
Issue: |
8 |
Pages: |
e72955 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilson EH |
Year: |
2006 |
Journal: |
J Immunol |
Title: |
B7RP-1-ICOS interactions are required for optimal infection-induced expansion of CD4+ Th1 and Th2 responses. |
Volume: |
177 |
Issue: |
4 |
Pages: |
2365-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gigoux M |
Year: |
2014 |
Journal: |
Mol Immunol |
Title: |
Inducible costimulator facilitates T-dependent B cell activation by augmenting IL-4 translation. |
Volume: |
59 |
Issue: |
1 |
Pages: |
46-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sebina I |
Year: |
2016 |
Journal: |
PLoS Pathog |
Title: |
IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection. |
Volume: |
12 |
Issue: |
11 |
Pages: |
e1005999 |
|
•
•
•
•
•
|
Publication |
First Author: |
Odegard JM |
Year: |
2008 |
Journal: |
J Exp Med |
Title: |
ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity. |
Volume: |
205 |
Issue: |
12 |
Pages: |
2873-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kosuge H |
Year: |
2006 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Critical role of inducible costimulator signaling in the development of arteriosclerosis. |
Volume: |
26 |
Issue: |
12 |
Pages: |
2660-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wong SC |
Year: |
2003 |
Journal: |
Blood |
Title: |
Impaired germinal center formation and recall T-cell-dependent immune responses in mice lacking the costimulatory ligand B7-H2. |
Volume: |
102 |
Issue: |
4 |
Pages: |
1381-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Geels SN |
Year: |
2024 |
Journal: |
Cancer Cell |
Title: |
Interruption of the intratumor CD8(+) TÂ cell:Treg crosstalk improves the efficacy of PD-1 immunotherapy. |
Volume: |
42 |
Issue: |
6 |
Pages: |
1051-1066.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tan AH |
Year: |
2008 |
Journal: |
J Biol Chem |
Title: |
T helper cell-specific regulation of inducible costimulator expression via distinct mechanisms mediated by T-bet and GATA-3. |
Volume: |
283 |
Issue: |
1 |
Pages: |
128-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iwai H |
Year: |
2003 |
Journal: |
J Immunol |
Title: |
Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis. |
Volume: |
171 |
Issue: |
6 |
Pages: |
2848-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen Q |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
A novel ICOS-independent, but CD28- and SAP-dependent, pathway of T cell-dependent, polysaccharide-specific humoral immunity in response to intact Streptococcus pneumoniae versus pneumococcal conjugate vaccine. |
Volume: |
181 |
Issue: |
12 |
Pages: |
8258-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diamantopoulos N |
Year: |
2024 |
Journal: |
J Immunol |
Title: |
ICOS-expressing Regulatory T Cells Influence the Composition of Antitumor CTL Populations. |
Volume: |
213 |
Issue: |
5 |
Pages: |
753-762 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang J |
Year: |
2022 |
Journal: |
J Immunol |
Title: |
ICOS-Deficient Regulatory T Cells Can Prevent Spontaneous Autoimmunity but Are Impaired in Controlling Acute Inflammation. |
Volume: |
209 |
Issue: |
2 |
Pages: |
301-309 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zang X |
Year: |
2006 |
Journal: |
Genomics |
Title: |
A genetic library screen for signaling proteins that interact with phosphorylated T cell costimulatory receptors. |
Volume: |
88 |
Issue: |
6 |
Pages: |
841-845 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marks E |
Year: |
2007 |
Journal: |
Infect Immun |
Title: |
Differential CD28 and inducible costimulatory molecule signaling requirements for protective CD4+ T-cell-mediated immunity against genital tract Chlamydia trachomatis infection. |
Volume: |
75 |
Issue: |
9 |
Pages: |
4638-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park H |
Year: |
2005 |
Journal: |
Nat Immunol |
Title: |
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. |
Volume: |
6 |
Issue: |
11 |
Pages: |
1133-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li X |
Year: |
2024 |
Journal: |
Immunity |
Title: |
Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation. |
Volume: |
57 |
Issue: |
7 |
Pages: |
1603-1617.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Flamar AL |
Year: |
2020 |
Journal: |
Immunity |
Title: |
Interleukin-33 Induces the Enzyme Tryptophan Hydroxylase 1 to Promote Inflammatory Group 2 Innate Lymphoid Cell-Mediated Immunity. |
Volume: |
52 |
Issue: |
4 |
Pages: |
606-619.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tao H |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
Differential controls of MAIT cell effector polarization by mTORC1/mTORC2 via integrating cytokine and costimulatory signals. |
Volume: |
12 |
Issue: |
1 |
Pages: |
2029 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chang JH |
Year: |
2014 |
Journal: |
J Exp Med |
Title: |
TRAF3 regulates the effector function of regulatory T cells and humoral immune responses. |
Volume: |
211 |
Issue: |
1 |
Pages: |
137-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Loke P |
Year: |
2005 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection. |
Volume: |
102 |
Issue: |
28 |
Pages: |
9872-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Elsner RA |
Year: |
2012 |
Journal: |
J Virol |
Title: |
Single and coexpression of CXCR4 and CXCR5 identifies CD4 T helper cells in distinct lymph node niches during influenza virus infection. |
Volume: |
86 |
Issue: |
13 |
Pages: |
7146-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vu F |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
ICOS, CD40, and lymphotoxin beta receptors signal sequentially and interdependently to initiate a germinal center reaction. |
Volume: |
180 |
Issue: |
4 |
Pages: |
2284-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arjunaraja S |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
The nature of an in vivo anti-capsular polysaccharide response is markedly influenced by the composition and/or architecture of the bacterial subcapsular domain. |
Volume: |
188 |
Issue: |
2 |
Pages: |
569-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Guo F |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
CD28 controls differentiation of regulatory T cells from naive CD4 T cells. |
Volume: |
181 |
Issue: |
4 |
Pages: |
2285-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lamhamedi-Cherradi SE |
Year: |
2001 |
Journal: |
Diabetes |
Title: |
Further mapping of the Idd5.1 locus for autoimmune diabetes in NOD mice. |
Volume: |
50 |
Issue: |
12 |
Pages: |
2874-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tan AH |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Regulation of mouse inducible costimulator (ICOS) expression by Fyn-NFATc2 and ERK signaling in T cells. |
Volume: |
281 |
Issue: |
39 |
Pages: |
28666-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Landuyt AE |
Year: |
2021 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
ICOS ligand and IL-10 synergize to promote host-microbiota mutualism. |
Volume: |
118 |
Issue: |
13 |
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Neumann K |
Year: |
2015 |
Journal: |
Eur J Immunol |
Title: |
Liver sinusoidal endothelial cells induce immunosuppressive IL-10-producing Th1 cells via the Notch pathway. |
Volume: |
45 |
Issue: |
7 |
Pages: |
2008-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cao Q |
Year: |
2023 |
Journal: |
JHEP Rep |
Title: |
Type 2 innate lymphoid cells are protective against hepatic ischaemia/reperfusion injury. |
Volume: |
5 |
Issue: |
10 |
Pages: |
100837 |
|
•
•
•
•
•
|
Publication |
First Author: |
Miyahira Y |
Year: |
2003 |
Journal: |
Immunol Lett |
Title: |
Involvement of ICOS-B7RP-1 costimulatory pathway in the regulation of immune responses to Leishmania major and Nippostrongylus brasiliensis infections. |
Volume: |
89 |
Issue: |
2-3 |
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