|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 172 out of 172 for Igfbp6

<< First    < Previous  |  Next >    Last >>
0.023s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
7529732 | J:20162
First Author: Schuller AG
Year: 1994
Journal: Mol Cell Endocrinol
Title: cDNA cloning and mRNA expression of the six mouse insulin-like growth factor binding proteins.
Volume: 104
Issue: 1
Pages: 57-66
•
•
•
•
•
Publication
15906375 | J:98927
First Author: Lipinski RJ
Year: 2005
Journal: Dev Dyn
Title: Sonic hedgehog signaling regulates the expression of insulin-like growth factor binding protein-6 during fetal prostate development.
Volume: 233
Issue: 3
Pages: 829-36
•
•
•
•
•
Publication
10579362 | J:58580
First Author: van Kleffens M
Year: 1999
Journal: Endocrinology
Title: Generation of antisera to mouse insulin-like growth factor binding proteins (IGFBP)-1 to -6: comparison of IGFBP protein and messenger ribonucleic acid localization in the mouse embryo.
Volume: 140
Issue: 12
Pages: 5944-52
•
•
•
•
•
Publication
10744620 | J:61500
First Author: Schneider MR
Year: 2000
Journal: FASEB J
Title: Transgenic mouse models for studying the functions of insulin-like growth factor-binding proteins.
Volume: 14
Issue: 5
Pages: 629-40
•
•
•
•
•
Publication
7684980 | J:12803
First Author: Schuller AG
Year: 1993
Journal: Endocrinology
Title: Gene expression of the six insulin-like growth factor binding proteins in the mouse conceptus during mid- and late gestation.
Volume: 132
Issue: 6
Pages: 2544-50
•
•
•
•
•
Publication
7511095 | J:18013
First Author: Hahnel A
Year: 1994
Journal: Endocrinology
Title: Insulin-like growth factor binding proteins are transcribed by preimplantation mouse embryos.
Volume: 134
Issue: 4
Pages: 1956-9
•
•
•
•
•
Publication
8923818 | J:36755
First Author: Mohan S
Year: 1996
Journal: J Clin Endocrinol Metab
Title: Insulin-like growth factor (IGF)-binding proteins in serum--do they have additional roles besides modulating the endocrine IGF actions?
Volume: 81
Issue: 11
Pages: 3817-20
•
•
•
•
•
Publication
9093203 | J:39926
First Author: Liu HC
Year: 1997
Journal: Fertil Steril
Title: Simultaneous detection of multiple gene expression in mouse and human individual preimplantation embryos.
Volume: 67
Issue: 4
Pages: 733-41
•
•
•
•
•
Publication
16047381 | J:103255
First Author: Suzuki Y
Year: 2005
Journal: Anat Rec A Discov Mol Cell Evol Biol
Title: Role of IGFBPs in the morphogenesis of lingual papillae.
Volume: 286
Issue: 1
Pages: 841-7
•
•
•
•
•
Publication
16338473 | J:106102
First Author: Carter AM
Year: 2006
Journal: Placenta
Title: The expression of insulin-like growth factor and insulin-like growth factor binding protein mRNAs in mouse placenta.
Volume: 27
Issue: 2-3
Pages: 278-90
•
•
•
•
•
Publication
8398121 | J:13309
First Author: Schultz GA
Year: 1993
Journal: Mol Reprod Dev
Title: Expression of IGF ligand and receptor genes during preimplantation mammalian development.
Volume: 35
Issue: 4
Pages: 414-20
•
•
•
•
•
Publication
9324049 | J:42775
First Author: Lindenbergh-Kortleve DJ
Year: 1997
Journal: Mol Cell Endocrinol
Title: Gene expression of the insulin-like growth factor system during mouse kidney development.
Volume: 132
Issue: 1-2
Pages: 81-91
•
•
•
•
•
Publication
9685224 | J:48168
First Author: van Kleffens M
Year: 1998
Journal: Mol Cell Endocrinol
Title: mRNA expression patterns of the IGF system during mouse limb bud development, determined by whole mount in situ hybridization.
Volume: 138
Issue: 1-2
Pages: 151-61
•
•
•
•
•
Publication
10502456 | J:59625
First Author: Kleffens M
Year: 1999
Journal: Growth Horm IGF Res
Title: mRNA and protein localization of the IGF system during mouse embryonic development in areas with apoptosis.
Volume: 9
Issue: 3
Pages: 195-204
•
•
•
•
•
Publication
22688304 | J:187514
First Author: Shibata S
Year: 2012
Journal: Eur J Histochem
Title: An in situ hybridization study of the insulin-like growth factor system in developing condylar cartilage of the fetal mouse mandible.
Volume: 56
Issue: 2
Pages: e23
•
•
•
•
•
Publication
7750499 | J:25933
First Author: Wang E
Year: 1995
Journal: Endocrinology
Title: Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis.
Volume: 136
Issue: 6
Pages: 2741-51
•
•
•
•
•
Publication
15721138 | J:98507
First Author: Catón J
Year: 2005
Journal: Arch Oral Biol
Title: IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes.
Volume: 50
Issue: 2
Pages: 123-9
•
•
•
•
•
Publication
35741102 | J:326523
 
First Author: Kheirollahi V
Year: 2022
Journal: Cells
Title: Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis.
Volume: 11
Issue: 12
•
•
•
•
•
Publication
23813480 | J:201076
First Author: Okano T
Year: 2013
Journal: Dev Dyn
Title: Expression of insulin-like growth factor binding proteins during mouse cochlear development.
Volume: 242
Issue: 10
Pages: 1210-21
•
•
•
•
•
Publication
24391734 | J:211117
First Author: Pais RS
Year: 2013
Journal: PLoS One
Title: Transcriptome analysis in prenatal IGF1-deficient mice identifies molecular pathways and target genes involved in distal lung differentiation.
Volume: 8
Issue: 12
Pages: e83028
•
•
•
•
•
Publication
27861515 | J:241923
First Author: López IP
Year: 2016
Journal: PLoS One
Title: Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation.
Volume: 11
Issue: 11
Pages: e0166388
•
•
•
•
•
Publication
31118232 | J:357459
 
First Author: Combes AN
Year: 2019
Journal: Development
Title: Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk.
Volume: 146
Issue: 12
•
•
•
•
•
Publication
23525041 | J:197621
First Author: Ueno M
Year: 2013
Journal: Nat Neurosci
Title: Layer V cortical neurons require microglial support for survival during postnatal development.
Volume: 16
Issue: 5
Pages: 543-51
•
•
•
•
•
Publication
26134413 | J:239654
 
First Author: Marongiu M
Year: 2015
Journal: BMC Dev Biol
Title: FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice.
Volume: 15
Pages: 27
•
•
•
•
•
Publication
- | J:29505
     
First Author: Copeland NG
Year: 1999
Journal: Database Release
Title: Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data
•
•
•
•
•
Publication
22159717 | J:265604
First Author: Naba A
Year: 2012
Journal: Mol Cell Proteomics
Title: The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Volume: 11
Issue: 4
Pages: M111.014647
•
•
•
•
•
Publication
24006456 | J:221550
First Author: Abonnenc M
Year: 2013
Journal: Circ Res
Title: Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Volume: 113
Issue: 10
Pages: 1138-47
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
•
•
•
•
•
Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
•
•
•
•
•
Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
•
•
•
•
•
Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
•
•
•
•
•
Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
•
•
•
•
•
Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
•
•
•
•
•
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Allele
Igfbp6<em2Smoc> | MGI:7290365
Name: insulin-like growth factor binding protein 6; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Allele
Igfbp6<em1Smoc> | MGI:7290364
Name: insulin-like growth factor binding protein 6; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
HT Experiment
E-GEOD-49383 | Gene expression data from mouse HDAC4 KO pups, postnatal day 3
Series Id: GSE49383
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
•
•
•
•
•
Publication
10980619 | -
First Author: Sueoka N
Year: 2000
Journal: Oncogene
Title: Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells.
Volume: 19
Issue: 38
Pages: 4432-6
•
•
•
•
•
Protein Domain
IPR022326 | IGFBP-6
Type: Family
Description: Insulin-like growth factors (IGFs)-I and -II are small secreted peptides that stimulate the survival, and promote the proliferation and differentiation, of many cell types []. In biological fluids, these growth factors are usually bound to IGF binding proteins (IGFBPs), which regulate their availability and activity by prolonging their half-life and modulating their receptor interactions. To date, six IGFBP family members have been identified (termed IGFBP1-6) []. They share a conserved gene (intron-exon) organisation and high IGF binding affinity. Structurally, the proteins also share a common domain architecture, possessing a conserved N-terminal IGFBP domain, a highly variable mid-section, and a thyroglobulin type-1 (Tg1) domain in their C-terminal regions. In addition to their role in the regulation of IGF activity, there is evidence for the direct association of IGFBPs with a variety of extracellular and cell surface molecules [, ], with consequent effects upon important biological processes. These include modulation of bone cell proliferation [], and growth arrest of breast and prostate cancer cells [, ]. IGFBP6 is a potent inducer of programmed cell death in lung cancer cells []. The protein may therefore represent a potential target as a cancer therapeutic.
•
•
•
•
•
Publication
17158767 | J:128679
First Author: Fontanière S
Year: 2006
Journal: Endocr Relat Cancer
Title: Gene expression profiling in insulinomas of Men1 beta-cell mutant mice reveals early genetic and epigenetic events involved in pancreatic beta-cell tumorigenesis.
Volume: 13
Issue: 4
Pages: 1223-36
•
•
•
•
•
Publication
24278330 | J:209778
First Author: Mielcarek M
Year: 2013
Journal: PLoS One
Title: HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo.
Volume: 8
Issue: 11
Pages: e80849
•
•
•
•
•
Publication
8874492 | -
First Author: Stewart CE
Year: 1996
Journal: Physiol Rev
Title: Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors.
Volume: 76
Issue: 4
Pages: 1005-26
•
•
•
•
•
Publication
10605625 | -
First Author: Hwa V
Year: 1999
Journal: Endocr Rev
Title: The insulin-like growth factor-binding protein (IGFBP) superfamily.
Volume: 20
Issue: 6
Pages: 761-87
•
•
•
•
•
Publication
7504671 | -
First Author: Oh Y
Year: 1993
Journal: J Biol Chem
Title: Demonstration of receptors for insulin-like growth factor binding protein-3 on Hs578T human breast cancer cells.
Volume: 268
Issue: 35
Pages: 26045-8
•
•
•
•
•
Publication
7499327 | -
First Author: Andress DL
Year: 1995
Journal: J Biol Chem
Title: Heparin modulates the binding of insulin-like growth factor (IGF) binding protein-5 to a membrane protein in osteoblastic cells.
Volume: 270
Issue: 47
Pages: 28289-96
•
•
•
•
•
Publication
7544787 | -
First Author: Mohan S
Year: 1995
Journal: J Biol Chem
Title: Studies on the mechanisms by which insulin-like growth factor (IGF) binding protein-4 (IGFBP-4) and IGFBP-5 modulate IGF actions in bone cells.
Volume: 270
Issue: 35
Pages: 20424-31
•
•
•
•
•
Publication
9115291 | -
First Author: Rajah R
Year: 1997
Journal: J Biol Chem
Title: Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism.
Volume: 272
Issue: 18
Pages: 12181-8
•
•
•
•
•
Protein
P47880
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom