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Search results 101 to 172 out of 172 for Igfbp6

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Type Details Score
Publication
7529732 | J:20162
First Author: Schuller AG
Year: 1994
Journal: Mol Cell Endocrinol
Title: cDNA cloning and mRNA expression of the six mouse insulin-like growth factor binding proteins.
Volume: 104
Issue: 1
Pages: 57-66
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Publication
15906375 | J:98927
First Author: Lipinski RJ
Year: 2005
Journal: Dev Dyn
Title: Sonic hedgehog signaling regulates the expression of insulin-like growth factor binding protein-6 during fetal prostate development.
Volume: 233
Issue: 3
Pages: 829-36
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Publication
10579362 | J:58580
First Author: van Kleffens M
Year: 1999
Journal: Endocrinology
Title: Generation of antisera to mouse insulin-like growth factor binding proteins (IGFBP)-1 to -6: comparison of IGFBP protein and messenger ribonucleic acid localization in the mouse embryo.
Volume: 140
Issue: 12
Pages: 5944-52
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Publication
10744620 | J:61500
First Author: Schneider MR
Year: 2000
Journal: FASEB J
Title: Transgenic mouse models for studying the functions of insulin-like growth factor-binding proteins.
Volume: 14
Issue: 5
Pages: 629-40
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Publication
7684980 | J:12803
First Author: Schuller AG
Year: 1993
Journal: Endocrinology
Title: Gene expression of the six insulin-like growth factor binding proteins in the mouse conceptus during mid- and late gestation.
Volume: 132
Issue: 6
Pages: 2544-50
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Publication
7511095 | J:18013
First Author: Hahnel A
Year: 1994
Journal: Endocrinology
Title: Insulin-like growth factor binding proteins are transcribed by preimplantation mouse embryos.
Volume: 134
Issue: 4
Pages: 1956-9
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Publication
8923818 | J:36755
First Author: Mohan S
Year: 1996
Journal: J Clin Endocrinol Metab
Title: Insulin-like growth factor (IGF)-binding proteins in serum--do they have additional roles besides modulating the endocrine IGF actions?
Volume: 81
Issue: 11
Pages: 3817-20
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Publication
9093203 | J:39926
First Author: Liu HC
Year: 1997
Journal: Fertil Steril
Title: Simultaneous detection of multiple gene expression in mouse and human individual preimplantation embryos.
Volume: 67
Issue: 4
Pages: 733-41
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Publication
16047381 | J:103255
First Author: Suzuki Y
Year: 2005
Journal: Anat Rec A Discov Mol Cell Evol Biol
Title: Role of IGFBPs in the morphogenesis of lingual papillae.
Volume: 286
Issue: 1
Pages: 841-7
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Publication
16338473 | J:106102
First Author: Carter AM
Year: 2006
Journal: Placenta
Title: The expression of insulin-like growth factor and insulin-like growth factor binding protein mRNAs in mouse placenta.
Volume: 27
Issue: 2-3
Pages: 278-90
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Publication
8398121 | J:13309
First Author: Schultz GA
Year: 1993
Journal: Mol Reprod Dev
Title: Expression of IGF ligand and receptor genes during preimplantation mammalian development.
Volume: 35
Issue: 4
Pages: 414-20
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Publication
9324049 | J:42775
First Author: Lindenbergh-Kortleve DJ
Year: 1997
Journal: Mol Cell Endocrinol
Title: Gene expression of the insulin-like growth factor system during mouse kidney development.
Volume: 132
Issue: 1-2
Pages: 81-91
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Publication
9685224 | J:48168
First Author: van Kleffens M
Year: 1998
Journal: Mol Cell Endocrinol
Title: mRNA expression patterns of the IGF system during mouse limb bud development, determined by whole mount in situ hybridization.
Volume: 138
Issue: 1-2
Pages: 151-61
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Publication
10502456 | J:59625
First Author: Kleffens M
Year: 1999
Journal: Growth Horm IGF Res
Title: mRNA and protein localization of the IGF system during mouse embryonic development in areas with apoptosis.
Volume: 9
Issue: 3
Pages: 195-204
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Publication
22688304 | J:187514
First Author: Shibata S
Year: 2012
Journal: Eur J Histochem
Title: An in situ hybridization study of the insulin-like growth factor system in developing condylar cartilage of the fetal mouse mandible.
Volume: 56
Issue: 2
Pages: e23
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Publication
7750499 | J:25933
First Author: Wang E
Year: 1995
Journal: Endocrinology
Title: Cellular patterns of insulin-like growth factor system gene expression in murine chondrogenesis and osteogenesis.
Volume: 136
Issue: 6
Pages: 2741-51
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Publication
15721138 | J:98507
First Author: Catón J
Year: 2005
Journal: Arch Oral Biol
Title: IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes.
Volume: 50
Issue: 2
Pages: 123-9
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Publication
35741102 | J:326523
 
First Author: Kheirollahi V
Year: 2022
Journal: Cells
Title: Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis.
Volume: 11
Issue: 12
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Publication
23813480 | J:201076
First Author: Okano T
Year: 2013
Journal: Dev Dyn
Title: Expression of insulin-like growth factor binding proteins during mouse cochlear development.
Volume: 242
Issue: 10
Pages: 1210-21
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Publication
24391734 | J:211117
First Author: Pais RS
Year: 2013
Journal: PLoS One
Title: Transcriptome analysis in prenatal IGF1-deficient mice identifies molecular pathways and target genes involved in distal lung differentiation.
Volume: 8
Issue: 12
Pages: e83028
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Publication
27861515 | J:241923
First Author: López IP
Year: 2016
Journal: PLoS One
Title: Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation.
Volume: 11
Issue: 11
Pages: e0166388
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Publication
31118232 | J:357459
 
First Author: Combes AN
Year: 2019
Journal: Development
Title: Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk.
Volume: 146
Issue: 12
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Publication
23525041 | J:197621
First Author: Ueno M
Year: 2013
Journal: Nat Neurosci
Title: Layer V cortical neurons require microglial support for survival during postnatal development.
Volume: 16
Issue: 5
Pages: 543-51
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Publication
26134413 | J:239654
 
First Author: Marongiu M
Year: 2015
Journal: BMC Dev Biol
Title: FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice.
Volume: 15
Pages: 27
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Publication
- | J:29505
     
First Author: Copeland NG
Year: 1999
Journal: Database Release
Title: Copeland-Jenkins (Frederick) Interspecific Backcross Mapping Data
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Publication
22159717 | J:265604
First Author: Naba A
Year: 2012
Journal: Mol Cell Proteomics
Title: The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Volume: 11
Issue: 4
Pages: M111.014647
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Publication
24006456 | J:221550
First Author: Abonnenc M
Year: 2013
Journal: Circ Res
Title: Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.
Volume: 113
Issue: 10
Pages: 1138-47
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
18554416 | J:139177
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Igfbp6<em2Smoc> | MGI:7290365
Name: insulin-like growth factor binding protein 6; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Igfbp6<em1Smoc> | MGI:7290364
Name: insulin-like growth factor binding protein 6; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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HT Experiment
E-GEOD-49383 | Gene expression data from mouse HDAC4 KO pups, postnatal day 3
Series Id: GSE49383
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
10980619 | -
First Author: Sueoka N
Year: 2000
Journal: Oncogene
Title: Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells.
Volume: 19
Issue: 38
Pages: 4432-6
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Protein Domain
IPR022326 | IGFBP-6
Type: Family
Description: Insulin-like growth factors (IGFs)-I and -II are small secreted peptides that stimulate the survival, and promote the proliferation and differentiation, of many cell types []. In biological fluids, these growth factors are usually bound to IGF binding proteins (IGFBPs), which regulate their availability and activity by prolonging their half-life and modulating their receptor interactions. To date, six IGFBP family members have been identified (termed IGFBP1-6) []. They share a conserved gene (intron-exon) organisation and high IGF binding affinity. Structurally, the proteins also share a common domain architecture, possessing a conserved N-terminal IGFBP domain, a highly variable mid-section, and a thyroglobulin type-1 (Tg1) domain in their C-terminal regions. In addition to their role in the regulation of IGF activity, there is evidence for the direct association of IGFBPs with a variety of extracellular and cell surface molecules [, ], with consequent effects upon important biological processes. These include modulation of bone cell proliferation [], and growth arrest of breast and prostate cancer cells [, ]. IGFBP6 is a potent inducer of programmed cell death in lung cancer cells []. The protein may therefore represent a potential target as a cancer therapeutic.
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Publication
17158767 | J:128679
First Author: Fontanière S
Year: 2006
Journal: Endocr Relat Cancer
Title: Gene expression profiling in insulinomas of Men1 beta-cell mutant mice reveals early genetic and epigenetic events involved in pancreatic beta-cell tumorigenesis.
Volume: 13
Issue: 4
Pages: 1223-36
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Publication
24278330 | J:209778
First Author: Mielcarek M
Year: 2013
Journal: PLoS One
Title: HDAC4 does not act as a protein deacetylase in the postnatal murine brain in vivo.
Volume: 8
Issue: 11
Pages: e80849
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Publication
8874492 | -
First Author: Stewart CE
Year: 1996
Journal: Physiol Rev
Title: Growth, differentiation, and survival: multiple physiological functions for insulin-like growth factors.
Volume: 76
Issue: 4
Pages: 1005-26
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Publication
10605625 | -
First Author: Hwa V
Year: 1999
Journal: Endocr Rev
Title: The insulin-like growth factor-binding protein (IGFBP) superfamily.
Volume: 20
Issue: 6
Pages: 761-87
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Publication
7504671 | -
First Author: Oh Y
Year: 1993
Journal: J Biol Chem
Title: Demonstration of receptors for insulin-like growth factor binding protein-3 on Hs578T human breast cancer cells.
Volume: 268
Issue: 35
Pages: 26045-8
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Publication
7499327 | -
First Author: Andress DL
Year: 1995
Journal: J Biol Chem
Title: Heparin modulates the binding of insulin-like growth factor (IGF) binding protein-5 to a membrane protein in osteoblastic cells.
Volume: 270
Issue: 47
Pages: 28289-96
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Publication
7544787 | -
First Author: Mohan S
Year: 1995
Journal: J Biol Chem
Title: Studies on the mechanisms by which insulin-like growth factor (IGF) binding protein-4 (IGFBP-4) and IGFBP-5 modulate IGF actions in bone cells.
Volume: 270
Issue: 35
Pages: 20424-31
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Publication
9115291 | -
First Author: Rajah R
Year: 1997
Journal: J Biol Chem
Title: Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism.
Volume: 272
Issue: 18
Pages: 12181-8
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Protein
P47880
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: false
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