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Search results 101 to 200 out of 227 for Igk-J

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Type Details Score
Publication
22287713 | J:181249
First Author: Aoki-Ota M
Year: 2012
Journal: J Immunol
Title: Skewed primary Igκ repertoire and V-J joining in C57BL/6 mice: implications for recombination accessibility and receptor editing.
Volume: 188
Issue: 5
Pages: 2305-15
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Publication
17404261 | J:145201
First Author: Gilbert MR
Year: 2007
Journal: J Immunol
Title: Dendritic cells from lupus-prone mice are defective in repressing immunoglobulin secretion.
Volume: 178
Issue: 8
Pages: 4803-10
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Publication
8112297 | J:19073
First Author: Kim JY
Year: 1994
Journal: EMBO J
Title: Crossing the SJL lambda locus into kappa-knockout mice reveals a dysfunction of the lambda 1-containing immunoglobulin receptor in B cell differentiation.
Volume: 13
Issue: 4
Pages: 827-34
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Publication
28755662 | J:259881
   
First Author: Shaheen S
Year: 2017
Journal: Elife
Title: Substrate stiffness governs the initiation of B cell activation by the concerted signaling of PKCβ and focal adhesion kinase.
Volume: 6
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Publication
7535094 | J:25735
First Author: Pricop L
Year: 1994
Journal: Int Immunol
Title: Antibody response elicited by T-dependent and T-independent antigens in gene targeted kappa-deficient mice.
Volume: 6
Issue: 12
Pages: 1839-47
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Publication
18178822 | J:215887
First Author: Rankin AL
Year: 2008
Journal: J Immunol
Title: CD4+ T cells recognizing a single self-peptide expressed by APCs induce spontaneous autoimmune arthritis.
Volume: 180
Issue: 2
Pages: 833-41
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Publication
16709806 | J:131775
First Author: Fields ML
Year: 2006
Journal: J Immunol
Title: Exogenous and endogenous TLR ligands activate anti-chromatin and polyreactive B cells.
Volume: 176
Issue: 11
Pages: 6491-502
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Publication
24888587 | J:211640
First Author: Park SK
Year: 2014
Journal: Genes Dev
Title: Pronounced cohabitation of active immunoglobulin genes from three different chromosomes in transcription factories during maximal antibody synthesis.
Volume: 28
Issue: 11
Pages: 1159-64
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Publication
15528332 | J:94297
First Author: Hayashi K
Year: 2004
Journal: J Immunol
Title: Impaired receptor editing in the primary B cell repertoire of BASH-deficient mice.
Volume: 173
Issue: 10
Pages: 5980-8
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:55926
 
First Author: Isobe T
Year: 1997
Journal: Natl Inst Genet Jpn Annual Report
Title: F. Genetic Strains Research Center. Analysis of the genetic structure of Pb hotspot in the Class II of MHC
Volume: 48
Pages: 87-101
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Publication
21908739 | J:179317
First Author: Verkoczy L
Year: 2011
Journal: J Immunol
Title: Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls.
Volume: 187
Issue: 7
Pages: 3785-97
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Publication
11222858 | J:115079
First Author: Casellas R
Year: 2001
Journal: Science
Title: Contribution of receptor editing to the antibody repertoire.
Volume: 291
Issue: 5508
Pages: 1541-4
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Publication
9763604 | J:115200
First Author: Xu H
Year: 1998
Journal: J Exp Med
Title: Regulation of anti-DNA B cells in recombination-activating gene-deficient mice.
Volume: 188
Issue: 7
Pages: 1247-54
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Publication
15153471 | J:90530
First Author: Steeves MA
Year: 2004
Journal: J Immunol
Title: Tolerance to DNA in (NZB x NZW)F1 mice that inherit an anti-DNA V(H) as a conventional micro H chain transgene but not as a V(H) knock-in transgene.
Volume: 172
Issue: 11
Pages: 6568-77
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Publication
19710460 | J:152303
First Author: Liu Z
Year: 2009
Journal: J Immunol
Title: Divergent roles of RelA and c-Rel in establishing chromosomal loops upon activation of the Igkappa gene.
Volume: 183
Issue: 6
Pages: 3819-30
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Publication
22249450 | J:181697
First Author: Xiong H
Year: 2012
Journal: J Exp Med
Title: Sequential class switching is required for the generation of high affinity IgE antibodies.
Volume: 209
Issue: 2
Pages: 353-64
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Allele
Rr163<tm1Lfdn> | MGI:3653474
Name: regulatory region 163; targeted mutation 1, Laurent Ferradini
Allele Type: Targeted
Attribute String: Modified regulatory region, Null/knockout
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Publication
8596914 | J:31727
First Author: Ferradini L
Year: 1996
Journal: Science
Title: Rearrangement-enhancing element upstream of the mouse immunoglobulin kappa chain J cluster.
Volume: 271
Issue: 5254
Pages: 1416-20
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Publication
16682638 | J:110100
First Author: Sirac C
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Light chain inclusion permits terminal B cell differentiation and does not necessarily result in autoreactivity.
Volume: 103
Issue: 20
Pages: 7747-52
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Publication
23280426 | J:193839
First Author: Lechouane F
Year: 2013
Journal: Eur J Immunol
Title: B-cell receptor signal strength influences terminal differentiation.
Volume: 43
Issue: 3
Pages: 619-28
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Publication
19155482 | J:144333
First Author: Xu CR
Year: 2009
Journal: J Immunol
Title: The epigenetic profile of Ig genes is dynamically regulated during B cell differentiation and is modulated by pre-B cell receptor signaling.
Volume: 182
Issue: 3
Pages: 1362-9
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Publication
18297074 | J:133224
First Author: Hewitt SL
Year: 2008
Journal: Nat Immunol
Title: Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells.
Volume: 9
Issue: 4
Pages: 396-404
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Allele
Rr158<tm1(Igh)Xu> | MGI:3757685
Name: regulatory region 158; targeted mutation 1, Yang Xu
Allele Type: Targeted
Attribute String: Modified regulatory region
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Allele
Rr158<tm2Xu> | MGI:3758449
Name: regulatory region 158; targeted mutation 2, Yang Xu
Allele Type: Targeted
Attribute String: Modified regulatory region
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Publication
8612132 | J:32727
First Author: Xu Y
Year: 1996
Journal: Immunity
Title: Deletion of the Ig kappa light chain intronic enhancer/matrix attachment region impairs but does not abolish V kappa J kappa rearrangement.
Volume: 4
Issue: 4
Pages: 377-85
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Publication
16818772 | J:134994
First Author: Inlay MA
Year: 2006
Journal: J Immunol
Title: Roles of the Ig kappa light chain intronic and 3' enhancers in Igk somatic hypermutation.
Volume: 177
Issue: 2
Pages: 1146-51
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Allele
Igk<tm1Cog> | MGI:3795279
Name: immunoglobulin kappa chain complex; targeted mutation 1, Michel Cogne
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Allele
Igk<tm1.1Cog> | MGI:3795280
Name: immunoglobulin kappa chain complex; targeted mutation 1.1, Michel Cogne
Allele Type: Targeted
Attribute String: Conditional ready, Humanized sequence, Inserted expressed sequence
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Allele
Igk<tm1.2Cog> | MGI:3795282
 
Name: immunoglobulin kappa chain complex; targeted mutation 1.2, Michel Cogne
Allele Type: Targeted
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Publication
26666261 | J:232596
First Author: Srour N
Year: 2016
Journal: J Exp Med
Title: A plasma cell differentiation quality control ablates B cell clones with biallelic Ig rearrangements and truncated Ig production.
Volume: 213
Issue: 1
Pages: 109-22
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Allele
Igk-J<tm1(CD4*)Mss> | MGI:3829660
Name: immunoglobulin kappa chain, joining region; targeted mutation 1, Mark S Schlissel
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Publication
31732530 | J:282195
First Author: Finney J
Year: 2019
Journal: J Immunol
Title: Cross-Reactivity to Kynureninase Tolerizes B Cells That Express the HIV-1 Broadly Neutralizing Antibody 2F5.
Volume: 203
Issue: 12
Pages: 3268-3281
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Allele
Igk<tm2.1Cog> | MGI:5788337
Name: immunoglobulin kappa chain complex; targeted mutation 2.1, Michel Cogne
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
29170366 | J:256269
First Author: Williams WB
Year: 2017
Journal: Nat Commun
Title: Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations.
Volume: 8
Issue: 1
Pages: 1732
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Allele
Igk<tm2Cog> | MGI:6148215
Name: immunoglobulin kappa chain complex; targeted mutation 2, Michel Cogne
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:6148945 | B6;129P2-Igk<tm2Cog>/Orl
Attribute String: mutant stock, targeted mutation
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Allele
Tg(IGH,IGKV@)HCo12Nlo | MGI:6505314
Name: transgene insertion HCo12, Nils Lonberg
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
32846123 | J:300935
First Author: Sangesland M
Year: 2020
Journal: Cell Rep
Title: A Single Human VH-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood.
Volume: 32
Issue: 8
Pages: 108065
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Allele
Tg(IGHV1-69,IGKV@)#Nlo | MGI:6504952
Name: transgene insertion, Nils Lonberg
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(IGHV1-2,IGKV@)#Nlo | MGI:6504953
Name: transgene insertion, Nils Lonberg
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Tg(IGH,IGKV@)HC2KCo5Nlo | MGI:6505564
Name: transgene insertion HC2KCo5, Nils Lonberg
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Publication
9631008 | J:301297
First Author: Fishwild DM
Year: 1996
Journal: Nat Biotechnol
Title: High-avidity human IgG kappa monoclonal antibodies from a novel strain of minilocus transgenic mice.
Volume: 14
Issue: 7
Pages: 845-51
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Allele
Tg(IGH,IGKV@)HC2KCo4Nlo | MGI:6505567
Name: transgene insertion HC2KCo4, Nils Lonberg
Allele Type: Transgenic
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Igk<tm3.1Cog> | MGI:7377755
Name: immunoglobulin kappa chain complex; targeted mutation 3.1, Michel Cogne
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Strain
MGI:7570343 | STOCK Igk<tm3.1Cog>/Orl
Attribute String: mutant strain, targeted mutation
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Allele
Igk<em1Smoc> | MGI:7290376
Name: immunoglobulin kappa chain complex; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6428896 | C57BL/6JSmoc-Igk<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:7624198 | C57BL/6JSmoc-Igl<em1Smoc> Igk<em1Smoc> Ighj4<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Igk<em2Smoc> | MGI:7290377
Name: immunoglobulin kappa chain complex; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6428061 | BALB/cJ-Igk<em2Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Genotype
Genotype
Symbol: Igk/Igk Iglc1/Iglc1
Background: involves: 129S7/SvEvBrd * C57BL/6J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igh-J/Igh-J Igk/Igk
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr158/Rr158
Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S2/SvPas * C57BL/6)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr163/Rr163<+>
Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CB20)
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr163/Rr163
Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * CB20)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igk-J/Igk-J<+> Igk/?
Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igk-J/Igk-J<+> Igk/?
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igk/Igk Iglc1/Iglc1<+>
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igk/Igk Iglc1/Iglc1
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igk/Igk Iglc1/Iglc1<+>
Background: involves: 129S7/SvEvBrd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igk/Igk Iglc1/Iglc1
Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igk/Igk Iglc1/Iglc1
Background: involves: 129S7/SvEvBrd
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igkc/Igkc<+> Rr158/Rr158<+>
Background: Not Specified
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr158/Rr158
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr158/Rr158
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Rr158/Rr158
Background: either: (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129S2/SvPas * C57BL/6)
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igk/Igk Tg(Mx1-cre)1Cgn/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igk/Igk
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igk/Igk Tg(Mx1-cre)1Cgn/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA * FVB/N
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igk/Igk
Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igkc/Igkc<+> Igk-J/Igk-J<+>
Background: involves: 129S4/SvJae
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igk/Igk Tg(H2-Ea-HA)HACIIAjca/? Tg(Tcra/Tcrb)1Vbo/?
Background: C.Cg-Igk Tg(H2-Ea-HA)HACIIAjca Tg(Tcra/Tcrb)1Vbo
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igk/Igk Tg(H2-Ea-HA)HACIIAjca/? Tg(TcraS106-1,TcrbS106-1)TS1SWAjca/?
Background: C.Cg-Igk Tg(H2-Ea-HA)HACIIAjca Tg(TcraS106-1,TcrbS106-1)TS1SWAjca
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Igh/Igh<+> Rr158/Rr158 Arhgef1/Arhgef1
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cx
Has Mutant Allele: true
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Publication
103004 | J:6069
First Author: Seidman JG
Year: 1978
Journal: Nature
Title: The arrangement and rearrangement of antibody genes.
Volume: 276
Issue: 5690
Pages: 790-5
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Publication
103631 | J:6075
First Author: Schibler U
Year: 1978
Journal: Cell
Title: The synthesis and processing of the messenger RNAs specifying heavy and light chain immunoglobulins in MPC-11 cells.
Volume: 15
Issue: 4
Pages: 1495-509
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Publication
6277505 | J:6697
First Author: Alt F
Year: 1981
Journal: Cell
Title: Organization and reorganization of immunoglobulin genes in A-MULV-transformed cells: rearrangement of heavy but not light chain genes.
Volume: 27
Issue: 2 Pt 1
Pages: 381-90
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Publication
6291785 | J:6897
First Author: Lewis S
Year: 1982
Journal: Cell
Title: Continuing kappa-gene rearrangement in a cell line transformed by Abelson murine leukemia virus.
Volume: 30
Issue: 3
Pages: 807-16
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Publication
6296832 | J:34871
First Author: Hawley RG
Year: 1982
Journal: Proc Natl Acad Sci U S A
Title: Mutant immunoglobulin genes have repetitive DNA elements inserted into their intervening sequences.
Volume: 79
Issue: 23
Pages: 7425-9
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Publication
6222379 | J:35040
First Author: Gearhart PJ
Year: 1983
Journal: Proc Natl Acad Sci U S A
Title: Clusters of point mutations are found exclusively around rearranged antibody variable genes.
Volume: 80
Issue: 11
Pages: 3439-43
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Publication
6409419 | J:7128
First Author: Queen C
Year: 1983
Journal: Cell
Title: Immunoglobulin gene transcription is activated by downstream sequence elements.
Volume: 33
Issue: 3
Pages: 741-8
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Publication
6415486 | J:7224
First Author: Stafford J
Year: 1983
Journal: Nature
Title: Cell-type specific expression of a transfected immunoglobulin gene.
Volume: 306
Issue: 5938
Pages: 77-9
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Publication
3927151 | J:7956
First Author: Kelley DE
Year: 1985
Journal: Mol Cell Biol
Title: Nonproductive kappa immunoglobulin genes: recombinational abnormalities and other lesions affecting transcription, RNA processing, turnover, and translation.
Volume: 5
Issue: 7
Pages: 1660-75
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Publication
3932578 | J:8073
First Author: Dzierzak EA
Year: 1985
Journal: J Exp Med
Title: Molecular characterization of antibodies bearing Id-460. II. Molecular basis for Id-460 expression.
Volume: 162
Issue: 5
Pages: 1494-511
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Publication
3085099 | J:35041
First Author: Riley SC
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: Preferential expression of variable region heavy chain gene segments by predominant 2,4-dinitrophenyl-specific BALB/c neonatal antibody clonotypes.
Volume: 83
Issue: 8
Pages: 2589-93
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Publication
3032783 | J:8678
First Author: Yang JN
Year: 1987
Journal: Immunogenetics
Title: The endogenous retrovirus Mtv-8 on mouse chromosome 6 maps near several kappa light chain markers.
Volume: 25
Issue: 4
Pages: 222-7
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Publication
3034625 | J:8717
First Author: Dildrop R
Year: 1987
Journal: Eur J Immunol
Title: A new V gene expressed in lambda-2 light chains of the mouse.
Volume: 17
Issue: 5
Pages: 731-4
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Publication
2898504 | J:9233
First Author: D'Hoostelaere LA
Year: 1988
Journal: J Immunol
Title: The Ig kappa L chain allelic groups among the Ig kappa haplotypes and Ig kappa crossover populations suggest a gene order.
Volume: 141
Issue: 2
Pages: 652-61
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Publication
2563357 | J:32326
First Author: Kofler R
Year: 1989
Journal: Immunogenetics
Title: Complexity, polymorphism, and connectivity of mouse Vk gene families.
Volume: 29
Issue: 2
Pages: 65-74
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Publication
2613230 | J:10238
First Author: Azen EA
Year: 1989
Journal: Genomics
Title: Prp (proline-rich protein) genes linked to markers Es-12 (esterase-12), Ea-10 (erythrocyte alloantigen), and loci on distal mouse chromosome 6.
Volume: 5
Issue: 3
Pages: 415-22
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Publication
2115001 | J:10628
First Author: Müller B
Year: 1990
Journal: Eur J Immunol
Title: A physical map and analysis of the murine C kappa-RS region show the presence of a conserved element.
Volume: 20
Issue: 6
Pages: 1409-11
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Publication
1974568 | J:10673
First Author: Shefner R
Year: 1990
Journal: J Immunol
Title: Identification of a new V kappa gene family that is highly expressed in hybridomas from an autoimmune mouse strain.
Volume: 145
Issue: 5
Pages: 1609-14
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2119497 | J:10739
First Author: Wellman AA
Year: 1990
Journal: Nucleic Acids Res
Title: Sequences of the Lym-1 antibody heavy and light chain variable regions.
Volume: 18
Issue: 17
Pages: 5281
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Publication
1916951 | J:11491
First Author: Kim SO
Year: 1991
Journal: Immunogenetics
Title: Polymorphism in V kappa 10 genes encoding L chains of antibodies bearing the Ars-A and A48 cross-reactive idiotypes.
Volume: 34
Issue: 4
Pages: 231-41
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Publication
1778474 | J:714
First Author: Deyev SM
Year: 1991
Journal: Genetica
Title: Allelic variants of rearranged immunoglobulin heavy and light chain genes in hybridoma PTF-02 and parent myeloma.
Volume: 85
Issue: 1
Pages: 45-51
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Publication
1542295 | J:720
First Author: Kofler H
Year: 1992
Journal: Mol Immunol
Title: Mechanism of allergic cross-reactions--III. cDNA cloning and variable-region sequence analysis of two IgE antibodies specific for trinitrophenyl.
Volume: 29
Issue: 2
Pages: 161-6
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Publication
1379680 | J:1672
First Author: Chen J
Year: 1992
Journal: Mol Immunol
Title: Variable region cDNA sequences of three mouse monoclonal anti-idiotypic antibodies specific for anti-alpha(1----6)dextrans with groove- or cavity-type combining sites.
Volume: 29
Issue: 9
Pages: 1121-9
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Publication
8436417 | J:4304
First Author: Henderson TJ
Year: 1993
Journal: Immunogenetics
Title: Characterization of a V kappa family in Mus musculus castaneus: sequence analysis.
Volume: 37
Issue: 6
Pages: 426-36
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Publication
8511672 | J:12597
First Author: Chou CL
Year: 1993
Journal: Somat Cell Mol Genet
Title: An insertion-deletion event in murine immunoglobulin kappa gene resembles mutations at heavy-chain disease loci.
Volume: 19
Issue: 2
Pages: 131-9
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