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Search results 101 to 200 out of 1602 for Ihh

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Type Details Score
GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674819
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331157
Age: embryonic day 11.5
Image: 6B
Note: Ihh expression was detected in the distal limb bud and tail bud. However, at the posterior margin where Shh was normally expressed, no Ihh expression was detected.
Specimen Label: 6B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331157
Age: embryonic day 11.5
Image: 6B
Note: Ihh expression was detected in the distal limb bud and tail bud. However, at the posterior margin where Shh was normally expressed, no Ihh expression was detected.
Specimen Label: 6B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:19209
Assay Type: RNA in situ
Annotation Date: 1999-03-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1677919
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:1331157
Age: embryonic day 11.5
Image: 6B
Note: Ihh expression was detected in the distal limb bud and tail bud. However, at the posterior margin where Shh was normally expressed, no Ihh expression was detected.
Specimen Label: 6B
Detected: true
Specimen Num: 2
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Publication
17707622 | J:130737
First Author: Tagariello A
Year: 2008
Journal: Matrix Biol
Title: Ucma--A novel secreted factor represents a highly specific marker for distal chondrocytes.
Volume: 27
Issue: 1
Pages: 3-11
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Publication
15951842 | J:99641
First Author: Kobayashi T
Year: 2005
Journal: J Clin Invest
Title: Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP.
Volume: 115
Issue: 7
Pages: 1734-42
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Publication
11748145 | J:73071
First Author: Long F
Year: 2001
Journal: Development
Title: Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation.
Volume: 128
Issue: 24
Pages: 5099-108
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Publication
23871669 | J:202107
First Author: Kakanj P
Year: 2013
Journal: Cell Rep
Title: Indian hedgehog controls proliferation and differentiation in skin tumorigenesis and protects against malignant progression.
Volume: 4
Issue: 2
Pages: 340-51
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Publication
8937649 | J:37482
First Author: Kronmiller JE
Year: 1996
Journal: Arch Oral Biol
Title: Spatial and temporal distribution of Indian hedgehog mRNA in the embryonic mouse mandible.
Volume: 41
Issue: 6
Pages: 577-83
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Publication
17409191 | J:120822
First Author: Maeda Y
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Indian Hedgehog produced by postnatal chondrocytes is essential for maintaining a growth plate and trabecular bone.
Volume: 104
Issue: 15
Pages: 6382-7
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Publication
21545794 | J:173631
First Author: Zacharias WJ
Year: 2011
Journal: Dev Biol
Title: Hedgehog signaling controls homeostasis of adult intestinal smooth muscle.
Volume: 355
Issue: 1
Pages: 152-62
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Publication
17343742 | J:128027
 
First Author: Gipp J
Year: 2007
Journal: Mol Cancer
Title: Hedgehog pathway activity in the LADY prostate tumor model.
Volume: 6
Pages: 19
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Publication
24428864 | J:318224
First Author: Zhou J
Year: 2014
Journal: Arthritis Res Ther
Title: Disrupting the Indian hedgehog signaling pathway in vivo attenuates surgically induced osteoarthritis progression in Col2a1-CreERT2; Ihhfl/fl mice.
Volume: 16
Issue: 1
Pages: R11
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Publication
16951680 | J:113097
First Author: Lee K
Year: 2006
Journal: Nat Genet
Title: Indian hedgehog is a major mediator of progesterone signaling in the mouse uterus.
Volume: 38
Issue: 10
Pages: 1204-9
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Publication
20056671 | J:159728
First Author: Franco HL
Year: 2010
Journal: Biol Reprod
Title: Ablation of Indian hedgehog in the murine uterus results in decreased cell cycle progression, aberrant epidermal growth factor signaling, and increased estrogen signaling.
Volume: 82
Issue: 4
Pages: 783-90
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Publication
10842064 | J:63182
First Author: Maye P
Year: 2000
Journal: Mech Dev
Title: Indian hedgehog signaling in extraembryonic endoderm and ectoderm differentiation in ES embryoid bodies.
Volume: 94
Issue: 1-2
Pages: 117-32
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Publication
15771625 | J:100378
First Author: MacLean HE
Year: 2005
Journal: Dev Growth Differ
Title: Localization of Indian hedgehog and PTH/PTHrP receptor expression in relation to chondrocyte proliferation during mouse bone development.
Volume: 47
Issue: 2
Pages: 59-63
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Publication
9237688 | J:41710
First Author: Takabatake T
Year: 1997
Journal: FEBS Lett
Title: Hedgehog and patched gene expression in adult ocular tissues.
Volume: 410
Issue: 2-3
Pages: 485-9
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Publication
22155527 | J:180304
First Author: Tu X
Year: 2012
Journal: Dev Biol
Title: Indian hedgehog requires additional effectors besides Runx2 to induce osteoblast differentiation.
Volume: 362
Issue: 1
Pages: 76-82
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Publication
10465785 | J:57297
First Author: St-Jacques B
Year: 1999
Journal: Genes Dev
Title: Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation.
Volume: 13
Issue: 16
Pages: 2072-86
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Publication
19369399 | J:148017
First Author: Cortes M
Year: 2009
Journal: Development
Title: Sulfation of chondroitin sulfate proteoglycans is necessary for proper Indian hedgehog signaling in the developing growth plate.
Volume: 136
Issue: 10
Pages: 1697-706
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Publication
26918743 | J:249087
First Author: Laurie LE
Year: 2016
Journal: PLoS One
Title: The Transcription Factor Hand1 Is Involved In Runx2-Ihh-Regulated Endochondral Ossification.
Volume: 11
Issue: 2
Pages: e0150263
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Publication
35835905 | J:333914
First Author: Hanna J
Year: 2022
Journal: Nat Commun
Title: Cell-autonomous Hedgehog signaling controls Th17 polarization and pathogenicity.
Volume: 13
Issue: 1
Pages: 4075
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Publication
19389374 | J:149459
First Author: Wuelling M
Year: 2009
Journal: Dev Biol
Title: Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3.
Volume: 328
Issue: 1
Pages: 40-53
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Publication
21537345 | J:200497
First Author: Ma G
Year: 2011
Journal: Cell Res
Title: Indian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levels.
Volume: 21
Issue: 9
Pages: 1343-57
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Publication
20542037 | J:267267
First Author: Kosinski C
Year: 2010
Journal: Gastroenterology
Title: Indian hedgehog regulates intestinal stem cell fate through epithelial-mesenchymal interactions during development.
Volume: 139
Issue: 3
Pages: 893-903
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Publication
32223017 | J:307182
First Author: Amano K
Year: 2020
Journal: FASEB J
Title: Indian hedgehog in craniofacial neural crest cells links to skeletal malocclusion by regulating associated cartilage formation and gene expression.
Volume: 34
Issue: 5
Pages: 6791-6807
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Publication
10208865 | J:54678
First Author: Akiyama H
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Indian hedgehog in the late-phase differentiation in mouse chondrogenic EC cells, ATDC5: upregulation of type X collagen and osteoprotegerin ligand mRNAs.
Volume: 257
Issue: 3
Pages: 814-20
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Publication
29788357 | J:263773
First Author: Liu C
Year: 2018
Journal: Endocrinology
Title: Reproductive, Physiological, and Molecular Outcomes in Female Mice Deficient in Dhh and Ihh.
Volume: 159
Issue: 7
Pages: 2563-2575
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Publication
20503377 | J:160585
First Author: Kesper DA
Year: 2010
Journal: Dev Dyn
Title: Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification.
Volume: 239
Issue: 6
Pages: 1818-26
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Publication
19590577 | J:157333
First Author: Capurro MI
Year: 2009
Journal: EMBO Rep
Title: Overgrowth of a mouse model of Simpson-Golabi-Behmel syndrome is partly mediated by Indian hedgehog.
Volume: 10
Issue: 8
Pages: 901-7
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Publication
35851381 | J:328519
First Author: Tsukasaki M
Year: 2022
Journal: Nat Commun
Title: Periosteal stem cells control growth plate stem cells during postnatal skeletal growth.
Volume: 13
Issue: 1
Pages: 4166
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Publication
21795282 | J:175769
First Author: Hsu SH
Year: 2011
Journal: Development
Title: Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu.
Volume: 138
Issue: 17
Pages: 3791-801
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Publication
11160153 | J:67277
First Author: Chung UI
Year: 2001
Journal: J Clin Invest
Title: Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development.
Volume: 107
Issue: 3
Pages: 295-304
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Publication
19109233 | J:145997
First Author: Outram SV
Year: 2009
Journal: Blood
Title: Indian hedgehog (Ihh) both promotes and restricts thymocyte differentiation.
Volume: 113
Issue: 10
Pages: 2217-28
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Publication
10926768 | J:64021
First Author: Lin X
Year: 2000
Journal: Dev Biol
Title: Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice.
Volume: 224
Issue: 2
Pages: 299-311
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Publication
17442891 | J:127461
First Author: Shimoyama A
Year: 2007
Journal: Mol Biol Cell
Title: Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function.
Volume: 18
Issue: 7
Pages: 2411-8
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Publication
17555518 | J:137923
First Author: Chin HJ
Year: 2007
Journal: Dev Growth Differ
Title: Studies on the role of Dlx5 in regulation of chondrocyte differentiation during endochondral ossification in the developing mouse limb.
Volume: 49
Issue: 6
Pages: 515-21
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Publication
22507129 | J:185430
First Author: Choi SW
Year: 2012
Journal: Biochem J
Title: Indian Hedgehog signalling triggers Nkx3.2 protein degradation during chondrocyte maturation.
Volume: 443
Issue: 3
Pages: 789-98
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Publication
25587042 | J:233350
First Author: Zhang F
Year: 2015
Journal: J Mol Cell Biol
Title: JMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in mice.
Volume: 7
Issue: 1
Pages: 23-34
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Publication
33707608 | J:306318
First Author: Ono K
Year: 2021
Journal: Commun Biol
Title: Dmrt2 promotes transition of endochondral bone formation by linking Sox9 and Runx2.
Volume: 4
Issue: 1
Pages: 326
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Publication
35765931 | J:327630
First Author: Li R
Year: 2022
Journal: Genesis
Title: Generation of an Ihh-mKate2-Dre knock-in mouse line.
Volume: 60
Issue: 6-7
Pages: e23488
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Publication
18582859 | J:139168
First Author: Dakubo GD
Year: 2008
Journal: Dev Biol
Title: Indian hedgehog signaling from endothelial cells is required for sclera and retinal pigment epithelium development in the mouse eye.
Volume: 320
Issue: 1
Pages: 242-55
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Publication
17507416 | J:122610
First Author: Koyama E
Year: 2007
Journal: Development
Title: Conditional Kif3a ablation causes abnormal hedgehog signaling topography, growth plate dysfunction, and excessive bone and cartilage formation during mouse skeletogenesis.
Volume: 134
Issue: 11
Pages: 2159-69
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Publication
25808752 | J:221866
 
First Author: Yoshida M
Year: 2015
Journal: Nat Commun
Title: The transcription factor Foxc1 is necessary for Ihh-Gli2-regulated endochondral ossification.
Volume: 6
Pages: 6653
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Publication
14993235 | J:88817
First Author: Smits P
Year: 2004
Journal: J Cell Biol
Title: Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate.
Volume: 164
Issue: 5
Pages: 747-58
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Publication
21557453 | J:178364
First Author: Lenton K
Year: 2011
Journal: Genesis
Title: Indian hedgehog positively regulates calvarial ossification and modulates bone morphogenetic protein signaling.
Volume: 49
Issue: 10
Pages: 784-96
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Publication
19035497 | J:143531
First Author: Chen X
Year: 2008
Journal: Arthritis Rheum
Title: Regulation of articular chondrocyte proliferation and differentiation by indian hedgehog and parathyroid hormone-related protein in mice.
Volume: 58
Issue: 12
Pages: 3788-97
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Publication
31449527 | J:279005
First Author: Schroeder N
Year: 2019
Journal: PLoS One
Title: Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bones.
Volume: 14
Issue: 8
Pages: e0218230
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Publication
11476578 | J:71184
First Author: Gritli-Linde A
Year: 2001
Journal: Dev Biol
Title: The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides.
Volume: 236
Issue: 2
Pages: 364-86
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Publication
9853822 | J:51143
First Author: Grabel L
Year: 1998
Journal: Int J Dev Biol
Title: Using EC and ES cell culture to study early development: recent observations on Indian hedgehog and Bmps.
Volume: 42
Issue: 7
Pages: 917-25
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Publication
12917489 | J:85704
 
First Author: Niemann C
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis.
Volume: 100 Suppl 1
Pages: 11873-80
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Publication
22879594 | J:191585
First Author: Takahata Y
Year: 2012
Journal: J Biol Chem
Title: Positive regulation by γ-aminobutyric acid B receptor subunit-1 of chondrogenesis through acceleration of nuclear translocation of activating transcription factor-4.
Volume: 287
Issue: 40
Pages: 33293-303
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Publication
31550480 | J:283400
First Author: Wuelling M
Year: 2020
Journal: Dev Biol
Title: Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophy.
Volume: 457
Issue: 1
Pages: 104-118
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Publication
30470823 | J:311829
First Author: Chong YC
Year: 2019
Journal: Oncogene
Title: Indian Hedgehog links obesity to development of hepatocellular carcinoma.
Volume: 38
Issue: 12
Pages: 2206-2222
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Publication
15576404 | J:94274
First Author: Hu H
Year: 2005
Journal: Development
Title: Sequential roles of Hedgehog and Wnt signaling in osteoblast development.
Volume: 132
Issue: 1
Pages: 49-60
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Publication
25307863 | J:232543
First Author: Büller NV
Year: 2015
Journal: Gastroenterology
Title: Stromal Indian hedgehog signaling is required for intestinal adenoma formation in mice.
Volume: 148
Issue: 1
Pages: 170-180.e6
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Publication
24821091 | J:232067
First Author: Tian F
Year: 2014
Journal: J Bone Miner Res
Title: Core binding factor beta (Cbfβ) controls the balance of chondrocyte proliferation and differentiation by upregulating Indian hedgehog (Ihh) expression and inhibiting parathyroid hormone-related protein receptor (PPR) expression in postnatal cartilage and bone formation.
Volume: 29
Issue: 7
Pages: 1564-1574
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Publication
24753031 | J:233232
First Author: Xing W
Year: 2014
Journal: J Bone Miner Res
Title: Epiphyseal chondrocyte secondary ossification centers require thyroid hormone activation of Indian hedgehog and osterix signaling.
Volume: 29
Issue: 10
Pages: 2262-75
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Publication
10050855 | J:53760
First Author: Chuang PT
Year: 1999
Journal: Nature
Title: Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein.
Volume: 397
Issue: 6720
Pages: 617-21
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Publication
21683695 | J:175458
First Author: Bren-Mattison Y
Year: 2011
Journal: Dev Biol
Title: Growth of limb muscle is dependent on skeletal-derived Indian hedgehog.
Volume: 356
Issue: 2
Pages: 486-95
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Publication
29545125 | J:267570
 
First Author: Piombo V
Year: 2018
Journal: Bone
Title: Signaling systems affecting the severity of multiple osteochondromas.
Volume: 111
Pages: 71-81
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Publication
15936916 | J:103007
First Author: DiPaola CP
Year: 2005
Journal: J Orthop Res
Title: Molecular signaling in intervertebral disk development.
Volume: 23
Issue: 5
Pages: 1112-9
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Publication
12050144 | J:77683
First Author: Kobayashi T
Year: 2002
Journal: Development
Title: PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps.
Volume: 129
Issue: 12
Pages: 2977-86
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Publication
18424451 | J:136877
First Author: Napierala D
Year: 2008
Journal: Hum Mol Genet
Title: Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome.
Volume: 17
Issue: 14
Pages: 2244-54
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Publication
34423857 | J:315670
First Author: Hruba E
Year: 2021
Journal: J Bone Miner Res
Title: Loss of Sprouty Produces a Ciliopathic Skeletal Phenotype in Mice Through Upregulation of Hedgehog Signaling.
Volume: 36
Issue: 11
Pages: 2258-2274
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Publication
26598695 | J:228128
First Author: Zheng Z
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Timing of androgen receptor disruption and estrogen exposure underlies a spectrum of congenital penile anomalies.
Volume: 112
Issue: 52
Pages: E7194-203
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Publication
38472182 | J:346064
First Author: Leung AOW
Year: 2024
Journal: Nat Commun
Title: Suppression of apoptosis impairs phalangeal joint formation in the pathogenesis of brachydactyly type A1.
Volume: 15
Issue: 1
Pages: 2229
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Publication
19272384 | J:360610
First Author: van Dop WA
Year: 2009
Journal: Gastroenterology
Title: Depletion of the colonic epithelial precursor cell compartment upon conditional activation of the hedgehog pathway.
Volume: 136
Issue: 7
Pages: 2195-2203.e1-7
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Publication
25639508 | J:226676
First Author: Lin YC
Year: 2015
Journal: J Bone Miner Res
Title: Disruption of Scube2 Impairs Endochondral Bone Formation.
Volume: 30
Issue: 7
Pages: 1255-67
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Publication
7589793 | J:29671
First Author: Bitgood MJ
Year: 1995
Journal: Dev Biol
Title: Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo.
Volume: 172
Issue: 1
Pages: 126-38
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Publication
10631175 | J:59287
First Author: Karp SJ
Year: 2000
Journal: Development
Title: Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways.
Volume: 127
Issue: 3
Pages: 543-8
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Publication
27666725 | J:241397
First Author: Kamper M
Year: 2017
Journal: Cell Tissue Res
Title: Absence of collagen IX accelerates hypertrophic differentiation in the embryonic mouse spine through a disturbance of the Ihh-PTHrP feedback loop.
Volume: 367
Issue: 2
Pages: 359-367
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Publication
11133164 | J:66902
First Author: Colnot C
Year: 2001
Journal: Dev Biol
Title: Uncoupling of chondrocyte death and vascular invasion in mouse galectin 3 null mutant bones.
Volume: 229
Issue: 1
Pages: 203-14
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Publication
22354840 | J:182744
First Author: Kohn A
Year: 2012
Journal: Development
Title: Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development.
Volume: 139
Issue: 6
Pages: 1198-212
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Publication
11171337 | J:67153
First Author: Long F
Year: 2001
Journal: Development
Title: The CREB family of activators is required for endochondral bone development.
Volume: 128
Issue: 4
Pages: 541-50
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Publication
26553654 | J:320311
First Author: Yang L
Year: 2016
Journal: Cell Tissue Res
Title: Augmented Indian hedgehog signaling in cranial neural crest cells leads to craniofacial abnormalities and dysplastic temporomandibular joint in mice.
Volume: 364
Issue: 1
Pages: 105-15
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Publication
17166921 | J:117033
First Author: Haycraft CJ
Year: 2007
Journal: Development
Title: Intraflagellar transport is essential for endochondral bone formation.
Volume: 134
Issue: 2
Pages: 307-16
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Publication
15811134 | J:97242
First Author: Zhang XQ
Year: 2005
Journal: Differentiation
Title: Gli1 is not required for Pdgfralpha expression during mouse embryonic development.
Volume: 73
Issue: 2-3
Pages: 109-19
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Publication
15107406 | J:89327
First Author: Yoshida CA
Year: 2004
Journal: Genes Dev
Title: Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog.
Volume: 18
Issue: 8
Pages: 952-63
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Publication
17660199 | J:124105
First Author: Ruiz-Perez VL
Year: 2007
Journal: Development
Title: Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia.
Volume: 134
Issue: 16
Pages: 2903-12
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Publication
28323137 | J:250431
First Author: Heinonen J
Year: 2017
Journal: Osteoarthritis Cartilage
Title: Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency.
Volume: 25
Issue: 7
Pages: 1132-1142
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Publication
11311154 | J:68722
First Author: Dyer MA
Year: 2001
Journal: Development
Title: Indian hedgehog activates hematopoiesis and vasculogenesis and can respecify prospective neurectodermal cell fate in the mouse embryo.
Volume: 128
Issue: 10
Pages: 1717-30
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Publication
38836497 | J:357740
First Author: Sorsby M
Year: 2024
Journal: J Bone Miner Res
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