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Search results 101 to 191 out of 191 for Il12rb1

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Type Details Score
Publication
19830723 | J:155466
First Author: Kurokawa M
Year: 2009
Journal: Eur J Immunol
Title: Regulatory role of DC-derived osteopontin in systemic allergen sensitization.
Volume: 39
Issue: 12
Pages: 3323-30
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Publication
16210644 | J:119107
First Author: Del Nagro CJ
Year: 2005
Journal: J Immunol
Title: A critical role for complement C3d and the B cell coreceptor (CD19/CD21) complex in the initiation of inflammatory arthritis.
Volume: 175
Issue: 8
Pages: 5379-89
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Publication
19306359 | J:156200
First Author: Jana M
Year: 2009
Journal: Glia
Title: IL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12R beta 1.
Volume: 57
Issue: 14
Pages: 1553-65
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Publication
15457342 | J:92935
First Author: de Souza CM
Year: 2004
Journal: Mamm Genome
Title: Quantitative trait loci in Chromosomes 3, 8, and 9 regulate antibody production against Salmonella flagellar antigens in the mouse.
Volume: 15
Issue: 8
Pages: 630-6
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Publication
19100623 | J:145167
First Author: Jana M
Year: 2009
Journal: Mol Immunol
Title: IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages.
Volume: 46
Issue: 5
Pages: 773-83
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Publication
23673666 | J:199653
First Author: Floss DM
Year: 2013
Journal: J Biol Chem
Title: Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor.
Volume: 288
Issue: 27
Pages: 19386-400
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Publication
16688182 | J:111568
First Author: Langowski JL
Year: 2006
Journal: Nature
Title: IL-23 promotes tumour incidence and growth.
Volume: 442
Issue: 7101
Pages: 461-5
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Publication
12023369 | J:76845
First Author: Parham C
Year: 2002
Journal: J Immunol
Title: A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R.
Volume: 168
Issue: 11
Pages: 5699-708
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Publication
12707353 | J:83020
First Author: Fairweather D
Year: 2003
Journal: J Immunol
Title: IL-12 receptor beta 1 and Toll-like receptor 4 increase IL-1 beta- and IL-18-associated myocarditis and coxsackievirus replication.
Volume: 170
Issue: 9
Pages: 4731-7
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Publication
24945711 | J:337975
First Author: Neal LM
Year: 2014
Journal: PLoS Pathog
Title: Toxoplasma gondii profilin promotes recruitment of Ly6Chi CCR2+ inflammatory monocytes that can confer resistance to bacterial infection.
Volume: 10
Issue: 6
Pages: e1004203
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Publication
16880257 | J:124393
First Author: Rangachari M
Year: 2006
Journal: J Exp Med
Title: T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17.
Volume: 203
Issue: 8
Pages: 2009-19
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Publication
24532579 | J:209908
First Author: Bielinska AU
Year: 2014
Journal: J Immunol
Title: Distinct pathways of humoral and cellular immunity induced with the mucosal administration of a nanoemulsion adjuvant.
Volume: 192
Issue: 6
Pages: 2722-33
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Publication
12165484 | J:120706
First Author: Freudenberg MA
Year: 2002
Journal: J Immunol
Title: Cutting edge: a murine, IL-12-independent pathway of IFN-gamma induction by gram-negative bacteria based on STAT4 activation by Type I IFN and IL-18 signaling.
Volume: 169
Issue: 4
Pages: 1665-8
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Publication
22711893 | J:189796
First Author: Rowe JH
Year: 2012
Journal: J Immunol
Title: Innate IFN-γ is essential for programmed death ligand-1-mediated T cell stimulation following Listeria monocytogenes infection.
Volume: 189
Issue: 2
Pages: 876-84
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Publication
19587012 | J:151706
First Author: Brahmachari S
Year: 2009
Journal: J Immunol
Title: Suppression of regulatory T cells by IL-12p40 homodimer via nitric oxide.
Volume: 183
Issue: 3
Pages: 2045-58
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Publication
24586521 | J:213436
First Author: Chognard G
Year: 2014
Journal: PLoS One
Title: The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation.
Volume: 9
Issue: 2
Pages: e89092
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Publication
16482511 | J:320271
First Author: Hoeve MA
Year: 2006
Journal: Eur J Immunol
Title: Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells.
Volume: 36
Issue: 3
Pages: 661-70
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Publication
18504307 | J:137020
First Author: Lochner M
Year: 2008
Journal: J Exp Med
Title: In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells.
Volume: 205
Issue: 6
Pages: 1381-93
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Publication
22306691 | J:181328
First Author: Collison LW
Year: 2012
Journal: Nat Immunol
Title: The composition and signaling of the IL-35 receptor are unconventional.
Volume: 13
Issue: 3
Pages: 290-9
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Publication
19088061 | J:319975
First Author: van de Wetering D
Year: 2009
Journal: Int Immunol
Title: IL-23 modulates CD56+/CD3- NK cell and CD56+/CD3+ NK-like T cell function differentially from IL-12.
Volume: 21
Issue: 2
Pages: 145-53
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Publication
11489994 | J:70821
First Author: Poltorak A
Year: 2001
Journal: J Immunol
Title: A point mutation in the IL-12R beta 2 gene underlies the IL-12 unresponsiveness of Lps-defective C57BL/10ScCr mice.
Volume: 167
Issue: 4
Pages: 2106-11
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Publication
23467089 | J:241283
First Author: Yosef N
Year: 2013
Journal: Nature
Title: Dynamic regulatory network controlling TH17 cell differentiation.
Volume: 496
Issue: 7446
Pages: 461-8
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Publication
19084435 | J:142654
First Author: Satoh-Takayama N
Year: 2008
Journal: Immunity
Title: Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense.
Volume: 29
Issue: 6
Pages: 958-70
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Publication
17506816 | J:148669
First Author: Coers J
Year: 2007
Journal: Cell Microbiol
Title: Restriction of Legionella pneumophila growth in macrophages requires the concerted action of cytokine and Naip5/Ipaf signalling pathways.
Volume: 9
Issue: 10
Pages: 2344-57
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Publication
15170228 | J:90100
First Author: Hernandez-Valladares M
Year: 2004
Journal: Mamm Genome
Title: Confirmation and dissection of QTL controlling resistance to malaria in mice.
Volume: 15
Issue: 5
Pages: 390-8
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Publication
15220916 | J:91804
First Author: Watanabe T
Year: 2004
Journal: Nat Immunol
Title: NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses.
Volume: 5
Issue: 8
Pages: 800-8
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Publication
15245428 | J:91218
First Author: Sundberg JP
Year: 2004
Journal: J Invest Dermatol
Title: Adult-onset Alopecia areata is a complex polygenic trait in the C3H/HeJ mouse model.
Volume: 123
Issue: 2
Pages: 294-7
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Publication
- | J:58777
     
First Author: Elliott R
Year: 2000
Journal: Personal Communication
Title: Chromosome Locations Based on RH mapping
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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DO Term
DOID:0111990 | immunodeficiency 30
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Allele
Il12rb1<tm1(IL12RB1)Smoc> | MGI:7290422
Name: interleukin 12 receptor, beta 1; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence
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Allele
Il12rb1<em1Cya> | MGI:7657279
Name: interleukin 12 receptor, beta 1; endonuclease-mediated mutation 1, Cyagen Biosciences
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:7657552 | C57BL/6N-Il12rb1<em1Cya>/Cya
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
16424222 | -
First Author: Piskin G
Year: 2006
Journal: J Immunol
Title: In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin.
Volume: 176
Issue: 3
Pages: 1908-15
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Protein Domain
IPR010831 | IL-23_alpha
Type: Family
Description: This entry represents interleukin-23 subunit alpha, IL-23A (also known as Interleukin-23 subunit p19) associates with IL-12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity []. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis []. Similar to IL-12, human IL-23 stimulates IFN-gamma production and proliferation in PHA blast T cells, as well as in CD45RO (memory) T cells [].
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Publication
32169842 | J:287330
First Author: Chen J
Year: 2020
Journal: J Immunol
Title: RNA-Binding Protein HuR Promotes Th17 Cell Differentiation and Can Be Targeted to Reduce Autoimmune Neuroinflammation.
Volume: 204
Issue: 8
Pages: 2076-2087
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Protein
Q9EQ14
Organism: Mus musculus/domesticus
Length: 196  
Fragment?: false
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Publication
8999038 | -
First Author: Mosley B
Year: 1996
Journal: J Biol Chem
Title: Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation.
Volume: 271
Issue: 51
Pages: 32635-43
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Protein Domain
IPR003529 | Hematopoietin_rcpt_Gp130_CS
Type: Conserved_site
Description: A number of receptors for lymphokines, hematopoietic growth factors and growth hormone-related molecules have been found to share a common binding domain. These receptors are designated as hematopoietin receptors []and the corresponding ligands as hematopoietins. Further, hematopoietins have been subdivided into two major structural groups: Large/long and small/short hematopoietins.One subset of individual receptor chains that are part of receptor complexes for large hematopoietins contain common structural elements in their extracellular parts: an immunoglobulin-like domain, an hematopoietin-receptor domain, and 3 fibronectin type-III domains (2 in the leptin receptor). This subgroup was designated as "Gp130 family of receptors"[]and contains the following chains: Leptin receptor (LPTR), Granulocyte colony stimulating factor receptor (GCSFR), Interleukin-6/-11/LIF/OSM/CNTF common beta chain (Gp130), Leukemia inhibiting factor receptor (LIFR), Oncostatin-M receptor beta chain (OSMR), Interleukin-12 receptor beta-1 chain (IL12RB1), Interleukin-12 receptor beta-2 chain (IL12RB2). A schematic representation of the structure of these receptors is shown below: +-------+-------------------------+-----------------xxxxxxx-----------------+|Ig-like| C C C C Extracellular | FnIII (x3) XXXXXXX Cytoplasmic |+-------+-|-|--|--|---------------+-----------------xxxxxxx-----------------+| | | | Transmembrane+-+ +--+These receptor chains homodimerize (GCSFR, Gp130, LPTR) or heterodimerize (Gp130 with LIFR or OSMR, IL12RB1 with IL12RB2) upon binding of the cognate cytokine: G-CSF, LIF, OSM, LPT, or the cytokine/alpha chain complex: IL-6/IL6RA, IL-11/IL11RA, CNTF/CNTFRA, IL-12 (p35/p40) [, ].
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Publication
8293462 | -
First Author: Kishimoto T
Year: 1994
Journal: Cell
Title: Cytokine signal transduction.
Volume: 76
Issue: 2
Pages: 253-62
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Protein
O70458
Organism: Mus musculus/domesticus
Length: 971  
Fragment?: false
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Protein
Q00560
Organism: Mus musculus/domesticus
Length: 917  
Fragment?: false
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Protein
P97378
Organism: Mus musculus/domesticus
Length: 874  
Fragment?: false
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Protein
B9EHD2
Organism: Mus musculus/domesticus
Length: 972  
Fragment?: false
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Protein
A0A0R4J268
Organism: Mus musculus/domesticus
Length: 970  
Fragment?: false
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Protein
G3X8V6
Organism: Mus musculus/domesticus
Length: 971  
Fragment?: false
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Protein
Q6PDI9
Organism: Mus musculus/domesticus
Length: 917  
Fragment?: false
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Protein
D3Z6H5
Organism: Mus musculus/domesticus
Length: 540  
Fragment?: false
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Protein
H6WCS3
Organism: Mus musculus/domesticus
Length: 917  
Fragment?: false
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Protein
P40223
Organism: Mus musculus/domesticus
Length: 837  
Fragment?: false
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Protein
P42703
Organism: Mus musculus/domesticus
Length: 1092  
Fragment?: false
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Protein
Q14BI3
Organism: Mus musculus/domesticus
Length: 729  
Fragment?: false
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Protein
Q3UKU5
Organism: Mus musculus/domesticus
Length: 719  
Fragment?: false
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Protein
Q3U234
Organism: Mus musculus/domesticus
Length: 1092  
Fragment?: false
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Protein
Q14AY3
Organism: Mus musculus/domesticus
Length: 837  
Fragment?: false
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Publication
1400369 | -
First Author: Boulay JL
Year: 1992
Journal: J Biol Chem
Title: The interleukin-4-related lymphokines and their binding to hematopoietin receptors.
Volume: 267
Issue: 29
Pages: 20525-8
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Protein
P48356
Organism: Mus musculus/domesticus
Length: 1162  
Fragment?: false
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Protein
Q3UNU8
Organism: Mus musculus/domesticus
Length: 892  
Fragment?: false
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Protein
Q3US58
Organism: Mus musculus/domesticus
Length: 894  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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