|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 174 out of 174 for Il34

<< First    < Previous  |  Next >    Last >>
0.022s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
21494622 | J:172221
First Author: Chen Z
Year: 2011
Journal: PLoS One
Title: The critical role of IL-34 in osteoclastogenesis.
Volume: 6
Issue: 4
Pages: e18689
•
•
•
•
•
Publication
27445335 | J:236151
First Author: Kuboyama K
Year: 2016
Journal: J Biol Chem
Title: Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: PLEIOTROPHIN-PTPRZ-A SIGNALING IS INVOLVED IN OLIGODENDROCYTE DIFFERENTIATION.
Volume: 291
Issue: 35
Pages: 18117-28
•
•
•
•
•
Publication
30622154 | J:292879
First Author: Wada Y
Year: 2019
Journal: J Am Soc Nephrol
Title: IL-34-Dependent Intrarenal and Systemic Mechanisms Promote Lupus Nephritis in MRL-Faslpr Mice.
Volume: 30
Issue: 2
Pages: 244-259
•
•
•
•
•
Publication
23392676 | J:269538
First Author: Gómez-Nicola D
Year: 2013
Journal: J Neurosci
Title: Regulation of microglial proliferation during chronic neurodegeneration.
Volume: 33
Issue: 6
Pages: 2481-93
•
•
•
•
•
Publication
20489731 | J:186351
First Author: Chihara T
Year: 2010
Journal: Cell Death Differ
Title: IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation.
Volume: 17
Issue: 12
Pages: 1917-27
•
•
•
•
•
Publication
22579672 | J:192992
First Author: Liu H
Year: 2012
Journal: Biochim Biophys Acta
Title: The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1.
Volume: 1824
Issue: 7
Pages: 938-45
•
•
•
•
•
Publication
23744080 | J:202720
First Author: Nandi S
Year: 2013
Journal: J Biol Chem
Title: Receptor-type protein-tyrosine phosphatase ζ is a functional receptor for interleukin-34.
Volume: 288
Issue: 30
Pages: 21972-86
•
•
•
•
•
Publication
31350310 | J:280062
First Author: Kana V
Year: 2019
Journal: J Exp Med
Title: CSF-1 controls cerebellar microglia and is required for motor function and social interaction.
Volume: 216
Issue: 10
Pages: 2265-2281
•
•
•
•
•
Publication
30687013 | J:273531
 
First Author: Wlodarczyk A
Year: 2018
Journal: Front Cell Neurosci
Title: CSF1R Stimulation Promotes Increased Neuroprotection by CD11c+ Microglia in EAE.
Volume: 12
Pages: 523
•
•
•
•
•
Publication
37001042 | J:338040
First Author: Xie X
Year: 2023
Journal: Blood
Title: TREM2 acts as a receptor for IL-34 to suppress acute myeloid leukemia in mice.
Volume: 141
Issue: 26
Pages: 3184-3198
•
•
•
•
•
Publication
26634935 | J:234684
First Author: Wang Y
Year: 2016
Journal: Eur J Immunol
Title: Nonredundant roles of keratinocyte-derived IL-34 and neutrophil-derived CSF1 in Langerhans cell renewal in the steady state and during inflammation.
Volume: 46
Issue: 3
Pages: 552-9
•
•
•
•
•
Publication
32439942 | J:293191
First Author: Wang PL
Year: 2020
Journal: Nat Commun
Title: Peripheral nerve resident macrophages share tissue-specific programming and features of activated microglia.
Volume: 11
Issue: 1
Pages: 2552
•
•
•
•
•
Publication
30850344 | J:280321
First Author: O'Koren EG
Year: 2019
Journal: Immunity
Title: Microglial Function Is Distinct in Different Anatomical Locations during Retinal Homeostasis and Degeneration.
Volume: 50
Issue: 3
Pages: 723-737.e7
•
•
•
•
•
Publication
32999463 | J:297311
First Author: Badimon A
Year: 2020
Journal: Nature
Title: Negative feedback control of neuronal activity by microglia.
Volume: 586
Issue: 7829
Pages: 417-423
•
•
•
•
•
Publication
39841599 | J:361494
First Author: Lehtonen H
Year: 2025
Journal: Cell Rep
Title: Early precursor-derived pituitary gland tissue-resident macrophages play a pivotal role in modulating hormonal balance.
Volume: 44
Issue: 2
Pages: 115227
•
•
•
•
•
Publication
28813662 | J:259032
First Author: Sierro F
Year: 2017
Journal: Immunity
Title: A Liver Capsular Network of Monocyte-Derived Macrophages Restricts Hepatic Dissemination of Intraperitoneal Bacteria by Neutrophil Recruitment.
Volume: 47
Issue: 2
Pages: 374-388.e6
•
•
•
•
•
Publication
32895539 | J:306423
First Author: Williams JW
Year: 2020
Journal: Nat Immunol
Title: Limited proliferation capacity of aortic intima resident macrophages requires monocyte recruitment for atherosclerotic plaque progression.
Volume: 21
Issue: 10
Pages: 1194-1204
•
•
•
•
•
Publication
22542597 | J:185808
First Author: Nandi S
Year: 2012
Journal: Dev Biol
Title: The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation.
Volume: 367
Issue: 2
Pages: 100-13
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
•
•
•
•
•
Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
•
•
•
•
•
Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
•
•
•
•
•
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Allele
Il34<em2Smoc> | MGI:7290511
Name: interleukin 34; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Strain
MGI:6428978 | C57BL/6JSmoc-Il34<em2Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
•
•
•
•
•
Allele
Il34<em1Smoc> | MGI:7290501
Name: interleukin 34; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Strain
MGI:6770856 | C57BL/6JSmoc-Il34<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Publication
39321806 | J:357545
First Author: Nian Z
Year: 2024
Journal: Immunity
Title: Interleukin-34-orchestrated tumor-associated macrophage reprogramming is required for tumor immune escape driven by p53 inactivation.
Volume: 57
Issue: 10
Pages: 2344-2361.e7
•
•
•
•
•
Publication
27013192 | J:231828
First Author: De I
Year: 2016
Journal: Cancer Res
Title: CSF1 Overexpression Promotes High-Grade Glioma Formation without Impacting the Polarization Status of Glioma-Associated Microglia and Macrophages.
Volume: 76
Issue: 9
Pages: 2552-60
•
•
•
•
•
Publication
7683918 | -
First Author: Bourette RP
Year: 1993
Journal: Blood
Title: Expression of human colony-stimulating factor-1 (CSF-1) receptor in murine pluripotent hematopoietic NFS-60 cells induces long-term proliferation in response to CSF-1 without loss of erythroid differentiation potential.
Volume: 81
Issue: 10
Pages: 2511-20
•
•
•
•
•
Publication
6582485 | -
First Author: Hampe A
Year: 1984
Journal: Proc Natl Acad Sci U S A
Title: Nucleotide sequence of the feline retroviral oncogene v-fms shows unexpected homology with oncogenes encoding tyrosine-specific protein kinases.
Volume: 81
Issue: 1
Pages: 85-9
•
•
•
•
•
Publication
14709771 | -
First Author: Sapi E
Year: 2004
Journal: Exp Biol Med (Maywood)
Title: The role of CSF-1 in normal physiology of mammary gland and breast cancer: an update.
Volume: 229
Issue: 1
Pages: 1-11
•
•
•
•
•
Publication
22197934 | -
First Author: Rademakers R
Year: 2011
Journal: Nat Genet
Title: Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids.
Volume: 44
Issue: 2
Pages: 200-5
•
•
•
•
•
Publication
2849512 | -
First Author: Woolford J
Year: 1988
Journal: Cell
Title: Activation of the feline c-fms proto-oncogene: multiple alterations are required to generate a fully transformed phenotype.
Volume: 55
Issue: 6
Pages: 965-77
•
•
•
•
•
Publication
1834054 | -
 
First Author: Tamura T
Year: 1991
Journal: Behring Inst Mitt
Title: Transforming mechanism of the feline sarcoma virus encoded v-fms oncogene product.
Issue: 89
Pages: 93-9
•
•
•
•
•
Publication
2843495 | -
 
First Author: Rettenmier CW
Year: 1986
Journal: Princess Takamatsu Symp
Title: Requirements for transformation by the fms oncogene product (CSF-1 receptor).
Volume: 17
Pages: 211-8
•
•
•
•
•
Protein Domain
IPR030658 | CSF-1_receptor
Type: Family
Description: This entry represents a macrophage colony-stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR) or CD115 (Cluster of Differentiation 115). CSF1R is a tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes []. CSF-1 and CSF-1R play an important role in the development of the mammary gland and may be involved in the process of mammary gland carcinogenesis []. Mutations in the CSF1R gene cause hereditary diffuse leukoencephalopathy with spheroids, which is an autosomal-dominant central nervous system white-matter disease with variable clinical presentations, including personality and behavioral changes, dementia, depression, parkinsonism, seizures and other phenotypes [].This entry also includes the tyrosine-protein kinase transforming protein v-fms from Feline sarcoma virus. CSF1R (the c-fms product) is its cellular counterpart. It differs in some amino acid substitutions and the replacement of 50 C-terminal amino acids by 11 unrelated residues in v-fms [, , ]. v-fms can bind CSF-1 and has constitutive tyrosine-specific protein kinase activity, providing growth stimulatory signals in the absence of ligand [].
•
•
•
•
•
Protein
P09581
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
•
•
•
•
•
Protein
Q3U1X4
Organism: Mus musculus/domesticus
Length: 945  
Fragment?: true
•
•
•
•
•
Protein
Q0P635
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
•
•
•
•
•
Protein
Q3U1Y3
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
•
•
•
•
•
Protein
Q3U4N8
Organism: Mus musculus/domesticus
Length: 922  
Fragment?: true
•
•
•
•
•
Protein
Q3UKC6
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
•
•
•
•
•
Protein
Q3U210
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
•
•
•
•
•
Protein
Q6NXV8
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
•
•
•
•
•
Protein
Q3U3W0
Organism: Mus musculus/domesticus
Length: 977  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom