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Search results 101 to 114 out of 114 for Impg2

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Type Details Score
Strain
MGI:7718112 | C57BL/6JSmoc-Impg2<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Genotype
Genotype
Symbol: Impg2/Impg2
Background: C57BL/6J-Impg2
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Impg2/Impg2
Background: C57BL/6J-Impg2
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110371 | retinitis pigmentosa 56
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Protein
Q8C8X6
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: false
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Publication
20673862 | -
First Author: Bandah-Rozenfeld D
Year: 2010
Journal: Am J Hum Genet
Title: Mutations in IMPG2, encoding interphotoreceptor matrix proteoglycan 2, cause autosomal-recessive retinitis pigmentosa.
Volume: 87
Issue: 2
Pages: 199-208
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Publication
1070225 | -
 
First Author: Castberg T
Year: 1976
Journal: Acta Med Scand Suppl
Title: Complications from the pacemaker pocket. Prophylaxis, treatment and results.
Volume: 596
Pages: 51-4
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Publication
23993198 | -
First Author: Manes G
Year: 2013
Journal: Am J Hum Genet
Title: Mutations in IMPG1 cause vitelliform macular dystrophies.
Volume: 93
Issue: 3
Pages: 571-8
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Protein Domain
IPR039861 | IMPG
Type: Family
Description: This entry includes interphotoreceptor matrix proteoglycans 1 and 2.IMPG1, also known as SPACR, is a sialoprotein associated with photoreceptor cones and rods protein. It is a secreted glycoprotein containing a central mucin-like domain and an EGF-like domain in the C-terminal region. It also contains two SEA domains (after sea urchin sperm protein, enterokinase, and agrin), a highly conserved structure composed of four anti-parallel �� sheets surrounded by �� helices in an O-linked glycosylation-rich environment. IMPG1 has been linked to vitelliform macular dystrophies [].Interphotoreceptor matrix proteoglycan 2 (IMPG2, also known as SPACRCAN) is a interphotoreceptor matrix proteoglycan that binds to chondroitin sulfate and hyaluronan. It may be involved in organisation of the insoluble interphotoreceptor matrix [, ]. Mutations in the IMPG2 gene cause retinitis pigmentosa 56 (RP56) []and vitelliform macular dystrophy 5 (VMD5) [].
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Publication
36140676 | J:378498
 
First Author: Olivier G
Year: 2022
Journal: Genes (Basel)
Title: SPACR Encoded by IMPG1 Is Essential for Photoreceptor Survival by Interplaying between the Interphotoreceptor Matrix and the Retinal Pigment Epithelium.
Volume: 13
Issue: 9
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Publication
19050768 | J:142700
 
First Author: Escher P
Year: 2008
Journal: Mol Vis
Title: Differential neuroglycan C expression during retinal degeneration in Rpe65-/- mice.
Volume: 14
Pages: 2126-35
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Protein
Q8R1W8
Organism: Mus musculus/domesticus
Length: 798  
Fragment?: false
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Protein
A0A140T8V8
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: true
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Protein
Q80XH2
Organism: Mus musculus/domesticus
Length: 1243  
Fragment?: false
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