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Search results 101 to 144 out of 144 for Ipmk

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Type Details Score
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
30420721 | -
First Author: Seacrist CD
Year: 2018
Journal: Sci Rep
Title: Crystallographic and kinetic analyses of human IPMK reveal disordered domains modulate ATP binding and kinase activity.
Volume: 8
Issue: 1
Pages: 16672
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GO Term
GO:0000823 | inositol-1,4,5-trisphosphate 6-kinase activity
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GO Term
GO:0000824 | inositol-1,4,5,6-tetrakisphosphate 3-kinase activity
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Protein
Q6PAT6
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: false
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Protein
H3BLD6
Organism: Mus musculus/domesticus
Length: 148  
Fragment?: true
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Protein
A0A0A6YVS3
Organism: Mus musculus/domesticus
Length: 73  
Fragment?: false
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Protein
Q8BKB2
Organism: Mus musculus/domesticus
Length: 644  
Fragment?: true
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Protein
A0A0A6YWA1
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: false
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Protein
F7CWH3
Organism: Mus musculus/domesticus
Length: 96  
Fragment?: false
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Protein
A0A0A6YXT7
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: false
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Protein
A0A0A6YVR5
Organism: Mus musculus/domesticus
Length: 145  
Fragment?: false
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Protein
A0A0A6YX46
Organism: Mus musculus/domesticus
Length: 151  
Fragment?: true
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Protein
A0A0A6YY18
Organism: Mus musculus/domesticus
Length: 110  
Fragment?: false
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Protein Domain
IPR038286 | IPK_sf
Type: Homologous_superfamily
Description: Inositol phosphates (IPs) act as signalling messengers to regulate various cellular processes such as growth. This entry includes a group of inositol polyphosphate kinase, including inositol polyphosphate multikinase Arg82 and Inositol hexakisphosphate/inositol heptakisphosphate kinase Kcs1 from budding yeast. They play important roles in vacuole biogenesis and the cell's response to certain environmental stresses. The kinase activity of Arg82 and Kcs1 is required for the production of soluble inositol phosphates []. Independently of its catalytic activity, Arg82 is crucial for assembling the Arg80-Mcm1 protein complex at the promoter region of genes involved in arginine metabolism [].This entry also includes human inositol hexakisphosphate kinase 1/2/3 (IP6K1/2/3)[], inositol polyphosphate multikinase (IPMK) []and inositol-trisphosphate 3-kinase A/B/C (IP3KA/B/C) []. They are involved in inositol phosphate biosynthesis []. Independently of its catalytic activity, IPMK mediates the activation of mammalian target of rapamycin (mTOR) in response to essential amino acids [. Crystallographic analysis showed that the disordered domains of IPMK modulates its kinase activity [].
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Protein Domain
IPR005522 | IPK
Type: Family
Description: Inositol phosphates (IPs) act as signalling messengers to regulate various cellular processes such as growth. This entry includes a group of inositol polyphosphate kinase, including inositol polyphosphate multikinase Arg82 and Inositol hexakisphosphate/inositol heptakisphosphate kinase Kcs1 from budding yeast. They play important roles in vacuole biogenesis and the cell's response to certain environmental stresses. The kinase activity of Arg82 and Kcs1 is required for the production of soluble inositol phosphates []. Independently of its catalytic activity, Arg82 is crucial for assembling the Arg80-Mcm1 protein complex at the promoter region of genes involved in arginine metabolism [].This entry also includes human inositol hexakisphosphate kinase 1/2/3 (IP6K1/2/3)[], inositol polyphosphate multikinase (IPMK) []and inositol-trisphosphate 3-kinase A/B/C (IP3KA/B/C) []. They are involved in inositol phosphate biosynthesis []. Independently of its catalytic activity, IPMK mediates the activation of mammalian target of rapamycin (mTOR) in response to essential amino acids [. Crystallographic analysis showed that the disordered domains of IPMK modulates its kinase activity [].
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Protein
Q7TS72
Organism: Mus musculus/domesticus
Length: 678  
Fragment?: false
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Protein
Q6PD10
Organism: Mus musculus/domesticus
Length: 433  
Fragment?: false
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Publication
11502751 | J:114043
First Author: Saiardi A
Year: 2001
Journal: J Biol Chem
Title: Identification and characterization of a novel inositol hexakisphosphate kinase.
Volume: 276
Issue: 42
Pages: 39179-85
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Protein
Q8BWD2
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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Protein
Q80V72
Organism: Mus musculus/domesticus
Length: 448  
Fragment?: false
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Protein
Q8R071
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
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Protein
Q7TT16
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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Protein
Q3UGJ0
Organism: Mus musculus/domesticus
Length: 272  
Fragment?: true
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Protein
B2RXC2
Organism: Mus musculus/domesticus
Length: 942  
Fragment?: false
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Protein
D3YWA2
Organism: Mus musculus/domesticus
Length: 397  
Fragment?: false
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Protein
A0A0A6YWM3
Organism: Mus musculus/domesticus
Length: 402  
Fragment?: false
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Protein
H3BIW9
Organism: Mus musculus/domesticus
Length: 235  
Fragment?: true
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Protein
B9EJ11
Organism: Mus musculus/domesticus
Length: 396  
Fragment?: false
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Protein
Q6A097
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: true
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Publication
12828642 | -
First Author: El Alami M
Year: 2003
Journal: Mol Microbiol
Title: Arg82p is a bifunctional protein whose inositol polyphosphate kinase activity is essential for nitrogen and PHO gene expression but not for Mcm1p chaperoning in yeast.
Volume: 49
Issue: 2
Pages: 457-68
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Publication
18498254 | -
First Author: Windhorst S
Year: 2008
Journal: Biochem J
Title: Ins(1,4,5)P3 3-kinase-A overexpression induces cytoskeletal reorganization via a kinase-independent mechanism.
Volume: 414
Issue: 3
Pages: 407-17
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Publication
23050966 | -
 
First Author: Lee JY
Year: 2012
Journal: Ann N Y Acad Sci
Title: Inositol polyphosphate multikinase signaling in the regulation of metabolism.
Volume: 1271
Pages: 68-74
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Publication
37456841 | J:338392
First Author: Tyagi R
Year: 2023
Journal: iScience
Title: Inositol polyphosphate multikinase modulates redox signaling through nuclear factor erythroid 2-related factor 2 and glutathione metabolism.
Volume: 26
Issue: 7
Pages: 107199
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Publication
39609127 | J:360990
First Author: Zou X
Year: 2024
Journal: Immunity
Title: Hypoxia-inducible factor 2α promotes pathogenic polarization of stem-like Th2 cells via modulation of phospholipid metabolism.
Volume: 57
Issue: 12
Pages: 2808-2826.e8
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Publication
31657647 | J:297593
First Author: Tu-Sekine B
Year: 2019
Journal: FASEB J
Title: Inositol polyphosphate multikinase is a metformin target that regulates cell migration.
Volume: 33
Issue: 12
Pages: 14137-14146
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