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Search results 101 to 106 out of 106 for Ipo9

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0.017s

Type

Details

Score

Protein

Q99LF1

Organism:	Mus musculus/domesticus
Length:	191
Fragment?:	false

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Protein

B1AXD8

Organism:	Mus musculus/domesticus
Length:	201
Fragment?:	false

•

Publication

30036395 | -

First Author:	Polanowska J
Year:	2018
Journal:	PLoS Genet
Title:	Evolutionary plasticity in the innate immune function of Akirin.
Volume:	14
Issue:	7
Pages:	e1007494

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Publication

32950464 | -

First Author:	Howard AM
Year:	2021
Journal:	Dev Biol
Title:	Akirin is critical for early tinman induction and subsequent formation of the heart in Drosophila melanogaster.
Volume:	469

Pages:	1-11

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Publication

34711951 | -

First Author:	de Almeida M
Year:	2021
Journal:	Nature
Title:	AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
Volume:	599
Issue:	7885
Pages:	491-496

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Protein Domain

IPR024132 | Akirin

Type:

Family

Description:

Akirin is a molecular adapter that acts as a bridge between a variety of multiprotein complexes, and which is required for embryonic development and for normal innate immune response[, ]. It plays a central role in immune gene expression in insects and mammals, linking the SWI/SNF chromatin-remodelling complex with the transcription factor NFkappaB [, ]. Ankirin-2 plays a key role in nuclear protein degradation by promoting import of proteasomes into the nucleus as it directly binds to fully assembled 20S proteasomes at one end and to nuclear import receptor IPO9 at the other end, bridging them together and mediating the import of pre-assembled proteasome complexes through the nuclear pore [].

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