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Search results 101 to 187 out of 187 for Irf2

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:4879837
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541066
Age: embryonic day 15.5
Image: GUDMAP:5597
Specimen Label: GUDMAP:5597
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4879837
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2874723
Stage: TS23
Assay Id: MGI:5541066
Age: embryonic day 15.5
Image: GUDMAP:5596
Specimen Label: GUDMAP:5596
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4879837
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541066
Age: embryonic day 15.5
Image: GUDMAP:5596
Specimen Label: GUDMAP:5596
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4879837
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541066
Age: embryonic day 15.5
Image: GUDMAP:5597
Specimen Label: GUDMAP:5597
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4879837
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:1796223
Stage: TS23
Assay Id: MGI:5541066
Age: embryonic day 15.5
Image: GUDMAP:5596
Specimen Label: GUDMAP:5596
Detected: false
Specimen Num: 1
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Publication
9120398 | J:38780
First Author: Fehr T
Year: 1997
Journal: J Exp Med
Title: Crucial role of interferon consensus sequence binding protein, but neither of interferon regulatory factor 1 nor of nitric oxide synthesis for protection against murine listeriosis.
Volume: 185
Issue: 5
Pages: 921-31
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Publication
19483695 | J:151334
First Author: Sato T
Year: 2009
Journal: Nat Med
Title: Interferon regulatory factor-2 protects quiescent hematopoietic stem cells from type I interferon-dependent exhaustion.
Volume: 15
Issue: 6
Pages: 696-700
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Publication
15004277 | J:88889
First Author: Ichikawa E
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Defective development of splenic and epidermal CD4+ dendritic cells in mice deficient for IFN regulatory factor-2.
Volume: 101
Issue: 11
Pages: 3909-14
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Publication
2475256 | J:17557
First Author: Harada H
Year: 1989
Journal: Cell
Title: Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes.
Volume: 58
Issue: 4
Pages: 729-39
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Publication
8402903 | J:64286
First Author: Matsuyama T
Year: 1993
Journal: Cell
Title: Targeted disruption of IRF-1 or IRF-2 results in abnormal type I IFN gene induction and aberrant lymphocyte development.
Volume: 75
Issue: 1
Pages: 83-97
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Publication
10934221 | J:63876
First Author: Lohoff M
Year: 2000
Journal: J Exp Med
Title: Deficiency in the transcription factor interferon regulatory factor (IRF)-2 leads to severely compromised development of natural killer and T helper type 1 cells.
Volume: 192
Issue: 3
Pages: 325-36
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Publication
8617930 | J:110841
First Author: Salkowski CA
Year: 1996
Journal: J Immunol
Title: Differential dysregulation of nitric oxide production in macrophages with targeted disruptions in IFN regulatory factor-1 and -2 genes.
Volume: 156
Issue: 9
Pages: 3107-10
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Publication
10859338 | J:62869
First Author: Blanco JC
Year: 2000
Journal: J Exp Med
Title: Interferon regulatory factor (IRF)-1 and IRF-2 regulate interferon gamma-dependent cyclooxygenase 2 expression.
Volume: 191
Issue: 12
Pages: 2131-44
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Publication
14983024 | J:90360
First Author: Honda K
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Negative regulation of IFN-alpha/beta signaling by IFN regulatory factor 2 for homeostatic development of dendritic cells.
Volume: 101
Issue: 8
Pages: 2416-21
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Publication
7650042 | J:28308
First Author: Horiuchi M
Year: 1995
Journal: J Biol Chem
Title: The growth-dependent expression of angiotensin II type 2 receptor is regulated by transcription factors interferon regulatory factor-1 and -2.
Volume: 270
Issue: 34
Pages: 20225-30
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Publication
23412092 | J:196707
First Author: Sato T
Year: 2013
Journal: Blood
Title: Novel interferon-based pre-transplantation conditioning in the treatment of a congenital metabolic disorder.
Volume: 121
Issue: 16
Pages: 3267-73
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Publication
10415056 | J:56995
First Author: Salkowski CA
Year: 1999
Journal: J Immunol
Title: IL-12 is dysregulated in macrophages from IRF-1 and IRF-2 knockout mice.
Volume: 163
Issue: 3
Pages: 1529-36
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Publication
22504642 | J:188674
First Author: Notake T
Year: 2012
Journal: J Immunol
Title: Differential requirements for IRF-2 in generation of CD1d-independent T cells bearing NK cell receptors.
Volume: 188
Issue: 10
Pages: 4838-45
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Publication
17709541 | J:125685
First Author: Arakura F
Year: 2007
Journal: J Immunol
Title: Genetic control directed toward spontaneous IFN-alpha/IFN-beta responses and downstream IFN-gamma expression influences the pathogenesis of a murine psoriasis-like skin disease.
Volume: 179
Issue: 5
Pages: 3249-57
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Publication
10524230 | J:57502
First Author: Mamane Y
Year: 1999
Journal: Gene
Title: Interferon regulatory factors: the next generation.
Volume: 237
Issue: 1
Pages: 1-14
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Publication
15494505 | J:93748
First Author: Kuo TC
Year: 2004
Journal: J Immunol
Title: B lymphocyte-induced maturation protein (Blimp)-1, IFN regulatory factor (IRF)-1, and IRF-2 can bind to the same regulatory sites.
Volume: 173
Issue: 9
Pages: 5556-63
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Publication
7843405 | J:22857
First Author: Kawakami T
Year: 1995
Journal: FEBS Lett
Title: Possible involvement of the transcription factor ISGF3 gamma in virus-induced expression of the IFN-beta gene.
Volume: 358
Issue: 3
Pages: 225-9
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Publication
2111015 | J:17559
First Author: Driggers PH
Year: 1990
Journal: Proc Natl Acad Sci U S A
Title: An interferon gamma-regulated protein that binds the interferon-inducible enhancer element of major histocompatibility complex class I genes.
Volume: 87
Issue: 10
Pages: 3743-7
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Publication
15879093 | J:98991
First Author: Taki S
Year: 2005
Journal: J Immunol
Title: IFN regulatory factor-2 deficiency revealed a novel checkpoint critical for the generation of peripheral NK cells.
Volume: 174
Issue: 10
Pages: 6005-12
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Publication
12960317 | J:85375
First Author: Ashkar AA
Year: 2003
Journal: J Immunol
Title: Assessment of requirements for IL-15 and IFN regulatory factors in uterine NK cell differentiation and function during pregnancy.
Volume: 171
Issue: 6
Pages: 2937-44
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Publication
22042864 | J:180225
First Author: Hayashi H
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Characterization of dsRNA-induced pancreatitis model reveals the regulatory role of IFN regulatory factor 2 (Irf2) in trypsinogen5 gene transcription.
Volume: 108
Issue: 46
Pages: 18766-71
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Publication
30783658 | J:277688
First Author: Okubo Y
Year: 2019
Journal: Int Immunol
Title: Generation of a common innate lymphoid cell progenitor requires interferon regulatory factor 2.
Volume: 31
Issue: 8
Pages: 489-498
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Publication
1442307 | J:25570
 
First Author: Tanaka N
Year: 1992
Journal: Adv Immunol
Title: Cytokine gene regulation: regulatory cis-elements and DNA binding factors involved in the interferon system.
Volume: 52
Pages: 263-81
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Publication
7822029 | J:22504
First Author: Barber SA
Year: 1995
Journal: Infect Immun
Title: Differential expression of interferon regulatory factor 1 (IRF-1), IRF-2, and interferon consensus sequence binding protein genes in lipopolysaccharide (LPS)-responsive and LPS-hyporesponsive macrophages.
Volume: 63
Issue: 2
Pages: 601-8
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Publication
7654369 | J:26126
First Author: Riego E
Year: 1995
Journal: Mol Reprod Dev
Title: Differential constitutive expression of interferon genes in early mouse embryos.
Volume: 41
Issue: 2
Pages: 157-66
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Publication
18955028 | J:144079
First Author: Kim EJ
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Ubc9-mediated sumoylation leads to transcriptional repression of IRF-1.
Volume: 377
Issue: 3
Pages: 952-6
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Publication
15914553 | J:118863
First Author: Hida S
Year: 2005
Journal: Blood
Title: Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance.
Volume: 106
Issue: 6
Pages: 2011-7
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Publication
11114377 | J:66034
First Author: Hida S
Year: 2000
Journal: Immunity
Title: CD8(+) T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-alpha/beta signaling.
Volume: 13
Issue: 5
Pages: 643-55
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Publication
11859135 | J:74725
First Author: Ko J
Year: 2002
Journal: J Immunol
Title: Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis.
Volume: 168
Issue: 5
Pages: 2433-40
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Publication
10364426 | J:55576
First Author: Li W
Year: 1999
Journal: Dev Biol
Title: Interferon regulatory transcription factors are constitutively expressed and spatially regulated in the mouse lens.
Volume: 210
Issue: 1
Pages: 44-55
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Publication
17429444 | J:121548
First Author: Gudjonsson JE
Year: 2007
Journal: J Invest Dermatol
Title: Mouse models of psoriasis.
Volume: 127
Issue: 6
Pages: 1292-308
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Publication
22366192 | J:184926
First Author: Blackburn J
Year: 2012
Journal: Dev Biol
Title: The role of Irf6 in tooth epithelial invagination.
Volume: 365
Issue: 1
Pages: 61-70
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Publication
16783635 | J:109795
First Author: Kenney-Hunt JP
Year: 2006
Journal: Mamm Genome
Title: Quantitative trait loci for body size components in mice.
Volume: 17
Issue: 6
Pages: 526-37
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
15618518 | J:91257
First Author: Gray PA
Year: 2004
Journal: Science
Title: Mouse brain organization revealed through direct genome-scale TF expression analysis.
Volume: 306
Issue: 5705
Pages: 2255-7
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
31471524 | J:279970
First Author: Kriegsman BA
Year: 2019
Journal: J Immunol
Title: Frequent Loss of IRF2 in Cancers Leads to Immune Evasion through Decreased MHC Class I Antigen Presentation and Increased PD-L1 Expression.
Volume: 203
Issue: 7
Pages: 1999-2010
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Allele
Irf2<em2Smoc> | MGI:7290571
Name: interferon regulatory factor 2; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6475608 | C57BL/6JSmoc-Irf2<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Irf2<em1Smoc> | MGI:7290570
Name: interferon regulatory factor 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Protein Domain
IPR017431 | IRF1/IRF2
Type: Family
Description: This entry represents the interferon regulatory factor 1/2.IRF1 is a transcriptional regulator involved in the regulation of several cellular responses, such as regulation of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage [, , , , , ].IRF2 is a multifunctional transcription factor that plays a pivotal role in regulation of apoptosis and cell cycle control [, , ]. It also plays an important role in modulating cellular responses to interferon (IFN) and viral infection []. It has an antagonistic role to IRF1 in transcriptional regulation of IFN and ISG genes []. While IRF1 acts as a positive regulator, IRF2 is known to repress IFN-mediated gene expression.
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Publication
23975864 | J:205843
First Author: Sjöstrand M
Year: 2013
Journal: J Immunol
Title: Expression of the immune regulator tripartite-motif 21 is controlled by IFN regulatory factors.
Volume: 191
Issue: 7
Pages: 3753-63
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Publication
32456211 | J:302405
 
First Author: Nakao M
Year: 2020
Journal: Int J Mol Sci
Title: Exacerbated Imiquimod-Induced Psoriasis-Like Skin Inflammation in IRF5-Deficient Mice.
Volume: 21
Issue: 10
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Publication
8760352 | J:34972
 
First Author: Roffet P
Year: 1996
Journal: Biochem J
Title: Identification of distal silencing elements in the murine interferon-A11 gene promoter.
Volume: 317 ( Pt 3)
Pages: 697-706
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Publication
11244049 | J:183979
 
First Author: Taniguchi T
Year: 2001
Journal: Annu Rev Immunol
Title: IRF family of transcription factors as regulators of host defense.
Volume: 19
Pages: 623-55
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Publication
11846974 | -
First Author: Romeo G
Year: 2002
Journal: J Interferon Cytokine Res
Title: IRF-1 as a negative regulator of cell proliferation.
Volume: 22
Issue: 1
Pages: 39-47
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Publication
15226432 | -
First Author: Oshima S
Year: 2004
Journal: Mol Cell Biol
Title: Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cells.
Volume: 24
Issue: 14
Pages: 6298-310
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Publication
22200613 | -
First Author: Armstrong MJ
Year: 2012
Journal: Cancer Lett
Title: Interferon Regulatory Factor 1 (IRF-1) induces p21(WAF1/CIP1) dependent cell cycle arrest and p21(WAF1/CIP1) independent modulation of survivin in cancer cells.
Volume: 319
Issue: 1
Pages: 56-65
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Publication
19851330 | -
First Author: Gao J
Year: 2010
Journal: Cell Death Differ
Title: IRF-1 transcriptionally upregulates PUMA, which mediates the mitochondrial apoptotic pathway in IRF-1-induced apoptosis in cancer cells.
Volume: 17
Issue: 4
Pages: 699-709
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Publication
15509808 | -
First Author: Dornan D
Year: 2004
Journal: Mol Cell Biol
Title: Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53.
Volume: 24
Issue: 22
Pages: 10083-98
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Publication
28769762 | J:276818
 
First Author: Cruz SA
Year: 2017
Journal: Front Cell Neurosci
Title: Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury.
Volume: 11
Pages: 201
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Publication
31982409 | J:299369
First Author: Liu X
Year: 2020
Journal: Gastroenterology
Title: Identification of Lineage-Specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution.
Volume: 158
Issue: 6
Pages: 1728-1744.e14
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Protein
P15314
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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Protein
Q3U5M1
Organism: Mus musculus/domesticus
Length: 304  
Fragment?: false
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Protein
Q5SX13
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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Protein
Q4FK18
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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