|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 488 for Irs1

0.016s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
First Author: Ueki K
Year: 2000
Journal: J Clin Invest
Title: Restored insulin-sensitivity in IRS-1-deficient mice treated by adenovirus-mediated gene therapy.
Volume: 105
Issue: 10
Pages: 1437-45
Publication
First Author: Hoshi K
Year: 2004
Journal: J Bone Miner Res
Title: Deficiency of insulin receptor substrate-1 impairs skeletal growth through early closure of epiphyseal cartilage.
Volume: 19
Issue: 2
Pages: 214-23
Publication
First Author: Zemva J
Year: 2013
Journal: Age (Dordr)
Title: Neuronal overexpression of insulin receptor substrate 2 leads to increased fat mass, insulin resistance, and glucose intolerance during aging.
Volume: 35
Issue: 5
Pages: 1881-97
Publication
First Author: Bolukbasi E
Year: 2017
Journal: Cell Rep
Title: Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity.
Volume: 21
Issue: 3
Pages: 641-653
Publication
First Author: Okin D
Year: 2016
Journal: Cell
Title: The Effect of Sustained Inflammation on Hepatic Mevalonate Pathway Results in Hyperglycemia.
Volume: 165
Issue: 2
Pages: 343-56
Publication
First Author: Man XF
Year: 2020
Journal: FASEB J
Title: Insulin receptor substrate-1 inhibits high-fat diet-induced obesity by browning of white adipose tissue through miR-503.
Volume: 34
Issue: 9
Pages: 12308-12323
Publication      
First Author: Turer E
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for runt.
Publication
First Author: Smith LK
Year: 1993
Journal: Biochem Biophys Res Commun
Title: The insulin receptor substrate (IRS-1) is a PEST protein that is susceptible to calpain degradation in vitro.
Volume: 196
Issue: 2
Pages: 767-72
Publication
First Author: Myers MG Jr
Year: 1994
Journal: Trends Biochem Sci
Title: The IRS-1 signaling system.
Volume: 19
Issue: 7
Pages: 289-93
Publication
First Author: Voliovitch H
Year: 1995
Journal: J Biol Chem
Title: Tyrosine phosphorylation of insulin receptor substrate-1 in vivo depends upon the presence of its pleckstrin homology region.
Volume: 270
Issue: 30
Pages: 18083-7
Publication
First Author: Araki E
Year: 1995
Journal: Mol Endocrinol
Title: Characterization and regulation of the mouse insulin receptor substrate gene promoter.
Volume: 9
Issue: 10
Pages: 1367-79
Publication
First Author: Isakoff SJ
Year: 1996
Journal: J Biol Chem
Title: Interaction between the phosphotyrosine binding domain of Shc and the insulin receptor is required for Shc phosphorylation by insulin in vivo.
Volume: 271
Issue: 8
Pages: 3959-62
Publication
First Author: Taouis M
Year: 1996
Journal: Gene
Title: Cloning of the chicken insulin receptor substrate 1 gene.
Volume: 178
Issue: 1-2
Pages: 51-5
Publication
First Author: Matsuda K
Year: 1997
Journal: Diabetes
Title: Cell-specific regulation of IRS-1 gene expression: role of E box and C/EBP binding site in HepG2 cells and CHO cells.
Volume: 46
Issue: 3
Pages: 354-62
Publication
First Author: Puscheck EE
Year: 1998
Journal: Mol Reprod Dev
Title: Insulin receptor substrate-1 is expressed at high levels in all cells of the peri-implantation mouse embryo.
Volume: 49
Issue: 4
Pages: 386-93
Publication
First Author: Wu A
Year: 2003
Journal: J Cell Physiol
Title: Nuclear translocation of insulin receptor substrate-1 by the insulin receptor in mouse embryo fibroblasts.
Volume: 195
Issue: 3
Pages: 453-60
Publication
First Author: Carlson CJ
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Mammalian target of rapamycin regulates IRS-1 serine 307 phosphorylation.
Volume: 316
Issue: 2
Pages: 533-9
Publication
First Author: Ko WC
Year: 2006
Journal: Neurosci Lett
Title: Effect of opioid mu-receptors activation on insulin signals damaged by tumor necrosis factor alpha in myoblast C2C12 cells.
Volume: 397
Issue: 3
Pages: 274-8
Publication
First Author: Yoo H
Year: 2004
Journal: J Lipid Res
Title: Quantifying carbon sources for de novo lipogenesis in wild-type and IRS-1 knockout brown adipocytes.
Volume: 45
Issue: 7
Pages: 1324-32
Publication
First Author: Murata Y
Year: 2007
Journal: Biochem Biophys Res Commun
Title: IRS-1 transgenic mice show increased epididymal fat mass and insulin resistance.
Volume: 364
Issue: 2
Pages: 301-7
Publication
First Author: Zhang J
Year: 2008
Journal: Biochem Biophys Res Commun
Title: The cell growth suppressor, mir-126, targets IRS-1.
Volume: 377
Issue: 1
Pages: 136-40
Publication
First Author: Hos D
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: Blockade of insulin receptor substrate-1 inhibits corneal lymphangiogenesis.
Volume: 52
Issue: 8
Pages: 5778-85
Publication
First Author: Boura-Halfon S
Year: 2010
Journal: Mol Endocrinol
Title: A novel domain mediates insulin-induced proteasomal degradation of insulin receptor substrate 1 (IRS-1).
Volume: 24
Issue: 11
Pages: 2179-92
Publication  
First Author: Song J
Year: 2015
Journal: Neuroscience
Title: Impairment of insulin receptor substrate 1 signaling by insulin resistance inhibits neurite outgrowth and aggravates neuronal cell death.
Volume: 301
Pages: 26-38
Publication
First Author: Chu F
Year: 2018
Journal: Clin Exp Immunol
Title: MicroRNA-126 deficiency enhanced the activation and function of CD4(+) T cells by elevating IRS-1 pathway.
Volume: 191
Issue: 2
Pages: 166-179
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 16
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Absent
Sex: Pooled
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: false
Specimen Num: 17
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1832128
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 21
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3511228
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 22
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1914328
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1742828
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 24
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3288928
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 25
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1718528
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 26
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1775128
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 27
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1683328
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 28
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1788628
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 29
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1789128
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 30
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1885228
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 31
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1866628
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 32
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3276428
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 33
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3519728
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 34
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3515128
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 35
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3528528
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 36
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3514028
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 37
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 38
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 39
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1775928
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 40
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 41
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 42
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 43
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:2992728
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 44
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:1204502
Age: postnatal week 6-8
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 45
GXD Expression    
Probe: MGI:1204500
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:1204502
Age: embryonic day 15-16
Image: st96_186
Specimen Label: None
Detected: true
Specimen Num: 46
GXD Expression      
Probe: MGI:1194961
Assay Type: Northern blot
Annotation Date: 2003-06-24
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2663668
Age: embryonic day 7.0
Specimen Label: 7 DAYS
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:1194961
Assay Type: Northern blot
Annotation Date: 2003-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2663668
Age: embryonic day 11.0
Specimen Label: 11 DAYS
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:1194961
Assay Type: Northern blot
Annotation Date: 2003-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2663668
Age: embryonic day 15.0
Specimen Label: 15 DAYS
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:1194961
Assay Type: Northern blot
Annotation Date: 2003-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2663668
Age: embryonic day 17.0
Specimen Label: 17 DAYS
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:3511488
Assay Type: Northern blot
Annotation Date: 2004-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3511489
Age: postnatal adult
Image: 2
Specimen Label: Brain
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:3511488
Assay Type: Northern blot
Annotation Date: 2004-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3511489
Age: postnatal adult
Image: 2
Specimen Label: Liver
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:3511486
Assay Type: RT-PCR
Annotation Date: 2004-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3511492
Age: embryonic day 3.5
Image: 1
Specimen Label: Blastocyst
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3511487
Assay Type: RT-PCR
Annotation Date: 2004-12-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3511493
Age: embryonic day 3.5
Image: 1
Specimen Label: Blastocyst
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4881444
Assay Type: RT-PCR
Annotation Date: 2011-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:4881510
Age: embryonic day 12.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4881444
Assay Type: RT-PCR
Annotation Date: 2011-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604220
Stage: TS20
Assay Id: MGI:4881510
Age: embryonic day 12.5
Specimen Label: WT
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4881444
Assay Type: RT-PCR
Annotation Date: 2011-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:4881510
Age: embryonic day 12.5
Specimen Label: Csf2-/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4881444
Assay Type: RT-PCR
Annotation Date: 2011-02-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1604220
Stage: TS20
Assay Id: MGI:4881510
Age: embryonic day 12.5
Specimen Label: Csf2-/-
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:4423547
Assay Type: RNA in situ
Annotation Date: 2023-08-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7516890
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
Publication
First Author: Kurosu H
Year: 2005
Journal: Science
Title: Suppression of aging in mice by the hormone Klotho.
Volume: 309
Issue: 5742
Pages: 1829-33
Publication
First Author: Tsukumo DM
Year: 2007
Journal: Diabetes
Title: Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance.
Volume: 56
Issue: 8
Pages: 1986-98
Publication
First Author: Shinoda Y
Year: 2010
Journal: J Cell Biochem
Title: Mechanisms underlying catabolic and anabolic functions of parathyroid hormone on bone by combination of culture systems of mouse cells.
Volume: 109
Issue: 4
Pages: 755-63
Publication
First Author: Minami K
Year: 2003
Journal: Am J Physiol Endocrinol Metab
Title: ATP-sensitive K+ channel-mediated glucose uptake is independent of IRS-1/phosphatidylinositol 3-kinase signaling.
Volume: 285
Issue: 6
Pages: E1289-96
Publication
First Author: Furusaka A
Year: 1995
Journal: Biochem Biophys Res Commun
Title: Ornithine decarboxylase induction during liver regeneration in IRS-1-deficient mice.
Volume: 216
Issue: 1
Pages: 284-90
Publication
First Author: Terauchi Y
Year: 2000
Journal: Diabetes
Title: Insulin effect during embryogenesis determines fetal growth: a possible molecular link between birth weight and susceptibility to type 2 diabetes.
Volume: 49
Issue: 1
Pages: 82-6
Publication
First Author: Terauchi Y
Year: 1997
Journal: J Clin Invest
Title: Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease.
Volume: 99
Issue: 5
Pages: 861-6
Publication
First Author: Nakatsu Y
Year: 2011
Journal: J Biol Chem
Title: Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 associates with insulin receptor substrate-1 and enhances insulin actions and adipogenesis.
Volume: 286
Issue: 23
Pages: 20812-22
Publication
First Author: Nakao R
Year: 2009
Journal: Mol Cell Biol
Title: Ubiquitin ligase Cbl-b is a negative regulator for insulin-like growth factor 1 signaling during muscle atrophy caused by unloading.
Volume: 29
Issue: 17
Pages: 4798-811
Publication
First Author: Nakamura T
Year: 2010
Journal: Cell
Title: Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis.
Volume: 140
Issue: 3
Pages: 338-48
Publication
First Author: Metz HE
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Insulin receptor substrate-1 deficiency drives a proinflammatory phenotype in KRAS mutant lung adenocarcinoma.
Volume: 113
Issue: 31
Pages: 8795-800
Publication
First Author: Guo Y
Year: 2016
Journal: FASEB J
Title: Insulin receptor substrate-1 time-dependently regulates bone formation by controlling collagen Iα2 expression via miR-342.
Volume: 30
Issue: 12
Pages: 4214-4226
Publication
First Author: Ahn J
Year: 2011
Journal: Biochem Biophys Res Commun
Title: High fat diet induced downregulation of microRNA-467b increased lipoprotein lipase in hepatic steatosis.
Volume: 414
Issue: 4
Pages: 664-9
Publication
First Author: Borge PD Jr
Year: 2003
Journal: J Biol Chem
Title: Insulin receptor substrate 1 regulation of sarco-endoplasmic reticulum calcium ATPase 3 in insulin-secreting beta-cells.
Volume: 278
Issue: 13
Pages: 11359-68
Publication
First Author: Kim JA
Year: 2005
Journal: J Biol Chem
Title: Phosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by Mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: cross-talk between inflammatory signaling and insulin signaling that may contribute to insulin resistance.
Volume: 280
Issue: 24
Pages: 23173-83
Publication
First Author: Ando Y
Year: 2015
Journal: J Biol Chem
Title: Tumor necrosis factor (TNF)-α-induced repression of GKAP42 protein levels through cGMP-dependent kinase (cGK)-Iα causes insulin resistance in 3T3-L1 adipocytes.
Volume: 290
Issue: 9
Pages: 5881-92