Type |
Details |
Score |
GXD Expression |
Probe: |
MGI:6257856 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-04-06 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:160362 |
Pattern: |
Not Specified |
Stage: |
TS02 |
Assay Id: |
MGI:6402918 |
Age: |
embryonic day 1.0 |
Image: |
1C 2 cell |
Note: |
Expression is nuclear. |
Specimen Label: |
1C 2 cell |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6257852 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-11-27 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:2991528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6258264 |
Age: |
postnatal adult |
Image: |
S1S |
|
Specimen Label: |
S1S |
Detected: |
true |
Specimen Num: |
27 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6257852 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-11-27 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1796228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6258264 |
Age: |
postnatal adult |
Image: |
S1R |
|
Specimen Label: |
S1R |
Detected: |
true |
Specimen Num: |
26 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6257852 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-11-27 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:3148828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6258264 |
Age: |
postnatal adult |
Image: |
1C |
|
Specimen Label: |
1C |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6257852 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-11-27 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:3656228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6258264 |
Age: |
postnatal adult |
Image: |
1E |
|
Specimen Label: |
1E |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Widiez T |
Year: |
2011 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
High nitrogen insensitive 9 (HNI9)-mediated systemic repression of root NO3- uptake is associated with changes in histone methylation. |
Volume: |
108 |
Issue: |
32 |
Pages: |
13329-34 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of IWS1 plant homologues, including AtIWS1/2 from Arabidopsis. AtIWS1, also known as HNI9, is an evolutionary conserved component of the RNA polymerase II complex. It plays a role in N signaling by regulating several hundred N-responsive genes in roots []. It interacts with transcription factor BES1 and is involved in plant steroid hormone brassinosteroid regulated gene expression []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory |
Year: |
2012 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by The Jackson Laboratory |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Function or Process or Component Unknown following Literature Review |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
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•
•
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•
|
UniProt Feature |
Begin: |
1 |
Description: |
Protein IWS1 homolog |
Type: |
chain |
End: |
766 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hashizaki E |
Year: |
2023 |
Journal: |
mBio |
Title: |
Toxoplasma IWS1 Determines Fitness in Interferon-γ-Activated Host Cells and Mice by Indirectly Regulating ROP18 mRNA Expression. |
Volume: |
14 |
Issue: |
1 |
Pages: |
e0325622 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
766
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
543
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
155
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
91
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
198
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
765
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Z |
Year: |
2007 |
Journal: |
Biochem Biophys Res Commun |
Title: |
A putative transcriptional elongation factor hIws1 is essential for mammalian cell proliferation. |
Volume: |
353 |
Issue: |
1 |
Pages: |
47-53 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoh SM |
Year: |
2008 |
Journal: |
Genes Dev |
Title: |
The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation. |
Volume: |
22 |
Issue: |
24 |
Pages: |
3422-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diebold ML |
Year: |
2010 |
Journal: |
EMBO J |
Title: |
The structure of an Iws1/Spt6 complex reveals an interaction domain conserved in TFIIS, Elongin A and Med26. |
Volume: |
29 |
Issue: |
23 |
Pages: |
3979-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sweet SM |
Year: |
2009 |
Journal: |
Mol Cell Proteomics |
Title: |
Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry. |
Volume: |
8 |
Issue: |
5 |
Pages: |
904-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Trost M |
Year: |
2009 |
Journal: |
Immunity |
Title: |
The phagosomal proteome in interferon-gamma-activated macrophages. |
Volume: |
30 |
Issue: |
1 |
Pages: |
143-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Villén J |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Large-scale phosphorylation analysis of mouse liver. |
Volume: |
104 |
Issue: |
5 |
Pages: |
1488-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huttlin EL |
Year: |
2010 |
Journal: |
Cell |
Title: |
A tissue-specific atlas of mouse protein phosphorylation and expression. |
Volume: |
143 |
Issue: |
7 |
Pages: |
1174-89 |
|
•
•
•
•
•
|
Publication |
First Author: |
Church DM |
Year: |
2009 |
Journal: |
PLoS Biol |
Title: |
Lineage-specific biology revealed by a finished genome assembly of the mouse. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e1000112 |
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•
•
•
•
•
|