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Search results 101 to 200 out of 261 for Kctd1

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Type Details Score
GXD Expression
GXD Expression
 
Probe: MGI:6728859
Assay Type: RNA in situ
Annotation Date: 2021-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3674122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6729675
Age: embryonic day 14.5
Image: S3K
Specimen Label: S3K
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:6728859
Assay Type: RNA in situ
Annotation Date: 2021-08-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3674122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6729675
Age: embryonic day 14.5
Image: S3L
Specimen Label: S3L
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:6728859
Assay Type: RNA in situ
Annotation Date: 2021-08-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3674324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6729675
Age: embryonic day 16.5
Image: S4K
Specimen Label: S4K
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
 
Probe: MGI:6728859
Assay Type: RNA in situ
Annotation Date: 2021-08-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3674324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6729675
Age: embryonic day 16.5
Image: S4L
Specimen Label: S4L
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
Probe: MGI:6728859
Assay Type: RNA in situ
Annotation Date: 2021-08-09
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3674225
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6729675
Age: embryonic day 17.0
Image: 2L
Note: There is minimal to no expression.
Specimen Label: 2L
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6728859
Assay Type: RNA in situ
Annotation Date: 2021-08-09
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3674225
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6729675
Age: embryonic day 17.0
Image: 2P
Note: There is minimal to no expression.
Specimen Label: 2P
Detected: true
Specimen Num: 4
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Publication
33460639 | J:303715
 
First Author: Woodruff ED
Year: 2021
Journal: Dev Biol
Title: Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development.
Volume: 472
Pages: 67-74
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Publication
29055695 | J:256883
First Author: Zhou J
Year: 2017
Journal: Biochim Biophys Acta
Title: Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system.
Volume: 1860
Issue: 12
Pages: 1159-1168
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: BTB/POZ domain-containing protein KCTD1
Type: chain
End: 257
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Protein
Q5M956
Organism: Mus musculus/domesticus
Length: 257  
Fragment?: false
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Protein
E9Q6T9
Organism: Mus musculus/domesticus
Length: 861  
Fragment?: false
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Protein
A0A3Q4EG48
Organism: Mus musculus/domesticus
Length: 180  
Fragment?: true
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Protein
Q5M956-2
Organism: Mus musculus/domesticus
Length: 265  
Fragment?: false
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Allele
Kctd1<tm1d(EUCOMM)Wtsi> | MGI:6502870
Name: potassium channel tetramerisation domain containing 1; targeted mutation 1d, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout
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HT Experiment
E-GEOD-47005 | Generation and standardized, systemic phenotypic analysis of Kctd1 mutant mice
Series Id: GSE47005
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
19115315 | -
First Author: Ding X
Year: 2009
Journal: J Cell Biochem
Title: The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation.
Volume: 106
Issue: 2
Pages: 285-95
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Publication
18358072 | -
First Author: Ding XF
Year: 2008
Journal: DNA Cell Biol
Title: Characterization and expression of a human KCTD1 gene containing the BTB domain, which mediates transcriptional repression and homomeric interactions.
Volume: 27
Issue: 5
Pages: 257-65
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Allele
Kctd1<tm1c(EUCOMM)Wtsi> | MGI:6502868
Name: potassium channel tetramerisation domain containing 1; targeted mutation 1c, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready
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Genotype
Genotype
Symbol: Kctd1/Kctd1 Kctd15/Kctd15 Tg(KRT14-cre)1Amc/?
Background: involves: C57BL/6N * C57BL/6NJ
Zygosity: cn
Has Mutant Allele: true
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DO Term
DOID:0111550 | scalp-ear-nipple syndrome
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Genotype
Genotype
Symbol: Kctd1/Kctd1 Tg(Six2-EGFP/cre)1Amc/?
Background: involves: C57BL/6J * C57BL/6N * CD-1
Zygosity: cn
Has Mutant Allele: true
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Publication
9886290 | -
First Author: Bixby KA
Year: 1999
Journal: Nat Struct Biol
Title: Zn2+-binding and molecular determinants of tetramerization in voltage-gated K+ channels.
Volume: 6
Issue: 1
Pages: 38-43
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Protein Domain
IPR003131 | T1-type_BTB
Type: Domain
Description: This domain can be found at the N terminus of voltage-gated potassium channel proteins, where represents a cytoplasmic tetramerisation domain (T1) involved in assembly of alpha-subunits into functional tetrameric channels []. This domain can also be found in proteins that are not potassium channels, like KCTD1 (potassium channel tetramerisation domain-containing protein 1). KCTD1 is though to be a nuclear protein that functions as a transcriptional repressor. In KCTD1, the T1-type BTB domain mediates homomeric protein-protein interactions [, ].
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Publication
27389986 | -
First Author: Wong TC
Year: 2016
Journal: Int J Dev Biol
Title: Genes regulated by potassium channel tetramerization domain containing 15 (Kctd15) in the developing neural crest.
Volume: 60
Issue: 4-6
Pages: 159-66
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Publication
22811273 | -
First Author: Takahashi C
Year: 2012
Journal: Int J Dev Biol
Title: Identification and characterization of Xenopus kctd15, an ectodermal gene repressed by the FGF pathway.
Volume: 56
Issue: 5
Pages: 393-402
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Publication
23382213 | -
First Author: Zarelli VE
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inhibition of neural crest formation by Kctd15 involves regulation of transcription factor AP-2.
Volume: 110
Issue: 8
Pages: 2870-5
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Publication
26334369 | -
First Author: Ji AX
Year: 2016
Journal: J Mol Biol
Title: Structural Insights into KCTD Protein Assembly and Cullin3 Recognition.
Volume: 428
Issue: 1
Pages: 92-107
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Publication
28963344 | -
First Author: Pinkas DM
Year: 2017
Journal: Biochem J
Title: Structural complexity in the KCTD family of Cullin3-dependent E3 ubiquitin ligases.
Volume: 474
Issue: 22
Pages: 3747-3761
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Protein Domain
IPR045904 | KCTD15_T1-type_BTB
Type: Domain
Description: This entry represents the BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain, also known as tetramerization (T1) domain, found in KCTD15 proteins from vertebrates. It is a versatile protein-protein interaction motif that facilitates homodimerization or heterodimerization. The BTB domains from KCTD family members can adopt a wide range of oligomerization geometries, including homodimerization, tetramerization, and pentamerization. The KCTD1 BTB domains, closely related to KCTD15, form pentamers [, ].BTB/POZ domain-containing protein KCTD15 (potassium channel tetramerization domain-containing protein 15) plays a role in the regulation of neural crest (NC) formation and other steps in embryonic development. It inhibits AP2 transcriptional activity by interacting with its activation domain [, , ].
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Protein
Q562E2
Organism: Mus musculus/domesticus
Length: 927  
Fragment?: false
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Protein
Q9CSZ1
Organism: Mus musculus/domesticus
Length: 164  
Fragment?: true
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Protein
E9PVN1
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: false
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Protein
D3Z7J5
Organism: Mus musculus/domesticus
Length: 40  
Fragment?: true
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Protein
E0CZ26
Organism: Mus musculus/domesticus
Length: 429  
Fragment?: false
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Protein
Q8CBQ4
Organism: Mus musculus/domesticus
Length: 156  
Fragment?: false
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Protein
A0A2R8VHM0
Organism: Mus musculus/domesticus
Length: 173  
Fragment?: true
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Protein
Q6DI85
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: false
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Protein
F7B6A4
Organism: Mus musculus/domesticus
Length: 206  
Fragment?: true
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Protein
E9PYP3
Organism: Mus musculus/domesticus
Length: 129  
Fragment?: false
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Protein
Q8K0E1
Organism: Mus musculus/domesticus
Length: 283  
Fragment?: false
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Protein
O70479
Organism: Mus musculus/domesticus
Length: 316  
Fragment?: false
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Protein
Q922M3
Organism: Mus musculus/domesticus
Length: 315  
Fragment?: false
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Protein
Q8BGV7
Organism: Mus musculus/domesticus
Length: 329  
Fragment?: false
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Protein
Q8K485
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: false
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Protein
Q6WVG3
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Protein
Q2TUM3
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: false
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Protein
Q9D7X1
Organism: Mus musculus/domesticus
Length: 259  
Fragment?: false
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Protein
Q50H33
Organism: Mus musculus/domesticus
Length: 476  
Fragment?: false
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Protein
Q8CEZ0
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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Protein
Q8BJK1
Organism: Mus musculus/domesticus
Length: 289  
Fragment?: false
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Protein
Q8VC57
Organism: Mus musculus/domesticus
Length: 234  
Fragment?: false
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Protein
Q8BNL5
Organism: Mus musculus/domesticus
Length: 237  
Fragment?: false
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Protein
Q5DTY9
Organism: Mus musculus/domesticus
Length: 427  
Fragment?: false
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Protein
A6H697
Organism: Mus musculus/domesticus
Length: 218  
Fragment?: false
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Protein
F8WGQ9
Organism: Mus musculus/domesticus
Length: 316  
Fragment?: false
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Protein
F6QXA3
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: true
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Protein
A0A0U1RPG8
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: false
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Protein
D3YZ64
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
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Protein
E0CYD2
Organism: Mus musculus/domesticus
Length: 243  
Fragment?: false
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Protein
S4R2A3
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: false
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Protein
F6SH71
Organism: Mus musculus/domesticus
Length: 278  
Fragment?: true
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Protein
Q8C004
Organism: Mus musculus/domesticus
Length: 222  
Fragment?: false
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Protein
A0A0U1RNG7
Organism: Mus musculus/domesticus
Length: 287  
Fragment?: false
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Protein
A0A0R4J2B2
Organism: Mus musculus/domesticus
Length: 327  
Fragment?: false
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Protein
A2A9V9
Organism: Mus musculus/domesticus
Length: 338  
Fragment?: false
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Protein
E0CZ97
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: false
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Protein
A0A0R4J000
Organism: Mus musculus/domesticus
Length: 234  
Fragment?: false
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Protein
Q6ZQH5
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: true
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Protein
E0CYQ0
Organism: Mus musculus/domesticus
Length: 289  
Fragment?: false
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Protein
Q8C7J6
Organism: Mus musculus/domesticus
Length: 292  
Fragment?: false
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Protein
Q5EER8
Organism: Mus musculus/domesticus
Length: 234  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom