Type |
Details |
Score |
Publication |
First Author: |
de Croft S |
Year: |
2012 |
Journal: |
Endocrinology |
Title: |
Spontaneous kisspeptin neuron firing in the adult mouse reveals marked sex and brain region differences but no support for a direct role in negative feedback. |
Volume: |
153 |
Issue: |
11 |
Pages: |
5384-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roa J |
Year: |
2018 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin signaling. |
Volume: |
115 |
Issue: |
45 |
Pages: |
E10758-E10767 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abreu AP |
Year: |
2020 |
Journal: |
J Clin Invest |
Title: |
MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons. |
Volume: |
130 |
Issue: |
8 |
Pages: |
4486-4500 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maguire CA |
Year: |
2017 |
Journal: |
Endocrinology |
Title: |
Tac1 Signaling Is Required for Sexual Maturation and Responsiveness of GnRH Neurons to Kisspeptin in the Male Mouse. |
Volume: |
158 |
Issue: |
7 |
Pages: |
2319-2329 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heppner KM |
Year: |
2017 |
Journal: |
eNeuro |
Title: |
GLP-1R Signaling Directly Activates Arcuate Nucleus Kisspeptin Action in Brain Slices but Does not Rescue Luteinizing Hormone Inhibition in Ovariectomized Mice During Negative Energy Balance. |
Volume: |
4 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Qiu J |
Year: |
2016 |
Journal: |
Elife |
Title: |
High-frequency stimulation-induced peptide release synchronizes arcuate kisspeptin neurons and excites GnRH neurons. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Greenwald-Yarnell ML |
Year: |
2016 |
Journal: |
Endocrinology |
Title: |
ERα in Tac2 Neurons Regulates Puberty Onset in Female Mice. |
Volume: |
157 |
Issue: |
4 |
Pages: |
1555-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Beymer M |
Year: |
2014 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Kisspeptin cell-specific PI3K signaling regulates hypothalamic kisspeptin expression and participates in the regulation of female fertility. |
Volume: |
307 |
Issue: |
11 |
Pages: |
E969-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stephens SBZ |
Year: |
2017 |
Journal: |
eNeuro |
Title: |
Effects of Selective Deletion of Tyrosine Hydroxylase from Kisspeptin Cells on Puberty and Reproduction in Male and Female Mice. |
Volume: |
4 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar D |
Year: |
2015 |
Journal: |
Endocrinology |
Title: |
Specialized subpopulations of kisspeptin neurons communicate with GnRH neurons in female mice. |
Volume: |
156 |
Issue: |
1 |
Pages: |
32-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Han SY |
Year: |
2020 |
Journal: |
Endocrinology |
Title: |
Neural Determinants of Pulsatile Luteinizing Hormone Secretion in Male Mice. |
Volume: |
161 |
Issue: |
2 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Clarkson J |
Year: |
2017 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Definition of the hypothalamic GnRH pulse generator in mice. |
Volume: |
114 |
Issue: |
47 |
Pages: |
E10216-E10223 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shen X |
Year: |
2022 |
Journal: |
Front Endocrinol (Lausanne) |
Title: |
Optogenetic stimulation of Kiss1(ARC) terminals in the AVPV induces surge-like luteinizing hormone secretion via glutamate release in mice. |
Volume: |
13 |
|
Pages: |
1036235 |
|
•
•
•
•
•
|
Publication |
First Author: |
Krull AA |
Year: |
2017 |
Journal: |
Endocrinology |
Title: |
A Comprehensive Method To Quantify Adaptations by Male and Female Mice With Hot Flashes Induced by the Neurokinin B Receptor Agonist Senktide. |
Volume: |
158 |
Issue: |
10 |
Pages: |
3259-3268 |
|
•
•
•
•
•
|
Publication |
First Author: |
Capela D |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Adult male mice exposure to nonylphenol alters courtship vocalizations and mating. |
Volume: |
8 |
Issue: |
1 |
Pages: |
2988 |
|
•
•
•
•
•
|
Publication |
First Author: |
Piet R |
Year: |
2013 |
Journal: |
J Neurosci |
Title: |
Estrous cycle plasticity in the hyperpolarization-activated current ih is mediated by circulating 17β-estradiol in preoptic area kisspeptin neurons. |
Volume: |
33 |
Issue: |
26 |
Pages: |
10828-39 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, African clawed |
|
•
•
•
•
•
|
Publication |
First Author: |
Jacobs DC |
Year: |
2016 |
Journal: |
Endocrinology |
Title: |
Evaluation of Immortalized AVPV- and Arcuate-Specific Neuronal Kisspeptin Cell Lines to Elucidate Potential Mechanisms of Estrogen Responsiveness and Temporal Gene Expression in Females. |
Volume: |
157 |
Issue: |
9 |
Pages: |
3410-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Berthon A |
Year: |
2020 |
Journal: |
Hum Mol Genet |
Title: |
Kisspeptin deficiency leads to abnormal adrenal glands and excess steroid hormone secretion. |
Volume: |
29 |
Issue: |
20 |
Pages: |
3443-3450 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang C |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
Kisspeptin-Activated Autophagy Independently Suppresses Non-Glucose-Stimulated Insulin Secretion from Pancreatic β-Cells. |
Volume: |
9 |
Issue: |
1 |
Pages: |
17451 |
|
•
•
•
•
•
|
Publication |
First Author: |
Salehi S |
Year: |
2015 |
Journal: |
Endocrinology |
Title: |
Developmental and endocrine regulation of kisspeptin expression in mouse Leydig cells. |
Volume: |
156 |
Issue: |
4 |
Pages: |
1514-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Silveira MA |
Year: |
2019 |
Journal: |
Brain Res |
Title: |
Acute effects of somatomammotropin hormones on neuronal components of the hypothalamic-pituitary-gonadal axis. |
Volume: |
1714 |
|
Pages: |
210-217 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2016 |
Journal: |
eNeuro |
Title: |
Excitability and Burst Generation of AVPV Kisspeptin Neurons Are Regulated by the Estrous Cycle Via Multiple Conductances Modulated by Estradiol Action. |
Volume: |
3 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Han SY |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
Mechanism of kisspeptin neuron synchronization for pulsatile hormone secretion in male mice. |
Volume: |
42 |
Issue: |
1 |
Pages: |
111914 |
|
•
•
•
•
•
|
Publication |
First Author: |
Silva MSB |
Year: |
2022 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Female sexual behavior is disrupted in a preclinical mouse model of PCOS via an attenuated hypothalamic nitric oxide pathway. |
Volume: |
119 |
Issue: |
30 |
Pages: |
e2203503119 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nandankar N |
Year: |
2021 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Deficiency of Arcuate Nucleus Kisspeptin Results in Post-Pubertal Central Hypogonadism. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Han SY |
Year: |
2019 |
Journal: |
Endocrinology |
Title: |
Characterization of GnRH Pulse Generator Activity in Male Mice Using GCaMP Fiber Photometry. |
Volume: |
160 |
Issue: |
3 |
Pages: |
557-567 |
|
•
•
•
•
•
|
Publication |
First Author: |
AvendaƱo MS |
Year: |
2024 |
Journal: |
Metabolism |
Title: |
The evolutionary conserved miR-137/325 tandem mediates obesity-induced hypogonadism and metabolic comorbidities by repressing hypothalamic kisspeptin. |
|
|
Pages: |
155932 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu X |
Year: |
2021 |
Journal: |
Elife |
Title: |
Highly redundant neuropeptide volume co-transmission underlying episodic activation of the GnRH neuron dendron. |
Volume: |
10 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Garcia-Galiano D |
Year: |
2020 |
Journal: |
J Neurosci |
Title: |
ERα Signaling in GHRH/Kiss1 Dual-Phenotype Neurons Plays Sex-Specific Roles in Growth and Puberty. |
Volume: |
40 |
Issue: |
49 |
Pages: |
9455-9466 |
|
•
•
•
•
•
|
Publication |
First Author: |
Negrón AL |
Year: |
2020 |
Journal: |
Int J Mol Sci |
Title: |
Targeted Deletion of PTEN in Kisspeptin Cells Results in Brain Region- and Sex-Specific Effects on Kisspeptin Expression and Gonadotropin Release. |
Volume: |
21 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yang JA |
Year: |
2016 |
Journal: |
Mol Cell Endocrinol |
Title: |
The interaction of fasting, caloric restriction, and diet-induced obesity with 17β-estradiol on the expression of KNDy neuropeptides and their receptors in the female mouse. |
Volume: |
437 |
|
Pages: |
35-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stephens SB |
Year: |
2015 |
Journal: |
Endocrinology |
Title: |
Absent Progesterone Signaling in Kisspeptin Neurons Disrupts the LH Surge and Impairs Fertility in Female Mice. |
Volume: |
156 |
Issue: |
9 |
Pages: |
3091-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Treen AK |
Year: |
2016 |
Journal: |
Mol Endocrinol |
Title: |
Divergent Regulation of ER and Kiss Genes by 17β-Estradiol in Hypothalamic ARC Versus AVPV Models. |
Volume: |
30 |
Issue: |
2 |
Pages: |
217-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
León S |
Year: |
2019 |
Journal: |
Endocrinology |
Title: |
Characterization of the Role of NKA in the Control of Puberty Onset and Gonadotropin Release in the Female Mouse. |
Volume: |
160 |
Issue: |
10 |
Pages: |
2453-2463 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mayer C |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Timing and completion of puberty in female mice depend on estrogen receptor alpha-signaling in kisspeptin neurons. |
Volume: |
107 |
Issue: |
52 |
Pages: |
22693-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moore AM |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
Kisspeptin/Neurokinin B/Dynorphin (KNDy) cells as integrators of diverse internal and external cues: evidence from viral-based monosynaptic tract-tracing in mice. |
Volume: |
9 |
Issue: |
1 |
Pages: |
14768 |
|
•
•
•
•
•
|
Publication |
First Author: |
Piet R |
Year: |
2018 |
Journal: |
J Neurosci |
Title: |
Dominant Neuropeptide Cotransmission in Kisspeptin-GABA Regulation of GnRH Neuron Firing Driving Ovulation. |
Volume: |
38 |
Issue: |
28 |
Pages: |
6310-6322 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gal A |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
Loss of Fertility in the Absence of Progesterone Receptor Expression in Kisspeptin Neurons of Female Mice. |
Volume: |
11 |
Issue: |
7 |
Pages: |
e0159534 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
126
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Terasaka T |
Year: |
2013 |
Journal: |
Mol Cell Endocrinol |
Title: |
Mutual interaction of kisspeptin, estrogen and bone morphogenetic protein-4 activity in GnRH regulation by GT1-7 cells. |
Volume: |
381 |
Issue: |
1-2 |
Pages: |
8-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Decourt C |
Year: |
2023 |
Journal: |
Endocrinology |
Title: |
Deletion of Androgen Receptors From Kisspeptin Neurons Prevents PCOS Features in a Letrozole Mouse Model. |
Volume: |
164 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mano T |
Year: |
2021 |
Journal: |
Cell Rep Methods |
Title: |
CUBIC-Cloud provides an integrative computational framework toward community-driven whole-mouse-brain mapping. |
Volume: |
1 |
Issue: |
2 |
Pages: |
100038 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brown RSE |
Year: |
2019 |
Journal: |
Endocrinology |
Title: |
Acute Suppression of LH Secretion by Prolactin in Female Mice Is Mediated by Kisspeptin Neurons in the Arcuate Nucleus. |
Volume: |
160 |
Issue: |
5 |
Pages: |
1323-1332 |
|
•
•
•
•
•
|
Publication |
First Author: |
McQuillan HJ |
Year: |
2022 |
Journal: |
Nat Commun |
Title: |
Definition of the estrogen negative feedback pathway controlling the GnRH pulse generator in female mice. |
Volume: |
13 |
Issue: |
1 |
Pages: |
7433 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cara AL |
Year: |
2023 |
Journal: |
Endocrinology |
Title: |
Deletion of Androgen Receptor in LepRb Cells Improves Estrous Cycles in Prenatally Androgenized Mice. |
Volume: |
164 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Silveira MA |
Year: |
2017 |
Journal: |
Mol Cell Endocrinol |
Title: |
STAT5 signaling in kisspeptin cells regulates the timing of puberty. |
Volume: |
448 |
|
Pages: |
55-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2019 |
Journal: |
Elife |
Title: |
Genetic dissection of the different roles of hypothalamic kisspeptin neurons in regulating female reproduction. |
Volume: |
8 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wang L |
Year: |
2018 |
Journal: |
J Neurosci |
Title: |
Glutamatergic Transmission to Hypothalamic Kisspeptin Neurons Is Differentially Regulated by Estradiol through Estrogen Receptor α in Adult Female Mice. |
Volume: |
38 |
Issue: |
5 |
Pages: |
1061-1072 |
|
•
•
•
•
•
|
Publication |
First Author: |
Navarro VM |
Year: |
2009 |
Journal: |
J Neurosci |
Title: |
Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse. |
Volume: |
29 |
Issue: |
38 |
Pages: |
11859-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martin C |
Year: |
2014 |
Journal: |
J Neurosci |
Title: |
Leptin-responsive GABAergic neurons regulate fertility through pathways that result in reduced kisspeptinergic tone. |
Volume: |
34 |
Issue: |
17 |
Pages: |
6047-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hellier V |
Year: |
2018 |
Journal: |
Nat Commun |
Title: |
Female sexual behavior in mice is controlled by kisspeptin neurons. |
Volume: |
9 |
Issue: |
1 |
Pages: |
400 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ladyman SR |
Year: |
2021 |
Journal: |
Elife |
Title: |
A reduction in voluntary physical activity in early pregnancy in mice is mediated by prolactin. |
Volume: |
10 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Schmid T |
Year: |
2013 |
Journal: |
J Neurosci |
Title: |
Loss of NSCL-2 in gonadotropin releasing hormone neurons leads to reduction of pro-opiomelanocortin neurons in specific hypothalamic nuclei and causes visceral obesity. |
Volume: |
33 |
Issue: |
25 |
Pages: |
10459-70 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Terao Y |
Year: |
2004 |
Journal: |
Biochim Biophys Acta |
Title: |
Expression of KiSS-1, a metastasis suppressor gene, in trophoblast giant cells of the rat placenta. |
Volume: |
1678 |
Issue: |
2-3 |
Pages: |
102-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Glanowska KM |
Year: |
2015 |
Journal: |
Endocrinology |
Title: |
Differential regulation of GnRH secretion in the preoptic area (POA) and the median eminence (ME) in male mice. |
Volume: |
156 |
Issue: |
1 |
Pages: |
231-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Padilla SL |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
A Neural Circuit Underlying the Generation of Hot Flushes. |
Volume: |
24 |
Issue: |
2 |
Pages: |
271-277 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pielecka-Fortuna J |
Year: |
2011 |
Journal: |
Biol Reprod |
Title: |
Voltage-gated potassium currents are targets of diurnal changes in estradiol feedback regulation and kisspeptin action on gonadotropin-releasing hormone neurons in mice. |
Volume: |
85 |
Issue: |
5 |
Pages: |
987-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang C |
Year: |
2013 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Kisspeptin inhibits a slow afterhyperpolarization current via protein kinase C and reduces spike frequency adaptation in GnRH neurons. |
Volume: |
304 |
Issue: |
11 |
Pages: |
E1237-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Telegdy G |
Year: |
2013 |
Journal: |
Behav Brain Res |
Title: |
The action of kisspeptin-13 on passive avoidance learning in mice. Involvement of transmitters. |
Volume: |
243 |
|
Pages: |
300-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Spampinato S |
Year: |
2011 |
Journal: |
Mol Pain |
Title: |
Hyperalgesic activity of kisspeptin in mice. |
Volume: |
7 |
|
Pages: |
90 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5316902 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-05-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737320 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5317109 |
Age: |
embryonic day 12.5 |
Image: |
3 |
|
Specimen Label: |
E12.5 +/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5316902 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-05-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737320 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5317109 |
Age: |
embryonic day 12.5 |
Image: |
3 |
|
Specimen Label: |
E12.5 -/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5316902 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-05-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737325 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5317109 |
Age: |
embryonic day 17.5 |
Image: |
3 |
|
Specimen Label: |
E17.5 +/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5316902 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-05-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737325 |
|
Stage: |
TS25 |
Assay Id: |
MGI:5317109 |
Age: |
embryonic day 17.5 |
Image: |
3 |
|
Specimen Label: |
E17.5 -/- |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5316902 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-05-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737327 |
|
Stage: |
TS27 |
Assay Id: |
MGI:5317109 |
Age: |
postnatal day 0 |
Image: |
3 |
|
Specimen Label: |
P0 +/+ |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5316902 |
Assay Type: |
RT-PCR |
Annotation Date: |
2012-05-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737327 |
|
Stage: |
TS27 |
Assay Id: |
MGI:5317109 |
Age: |
postnatal day 0 |
Image: |
3 |
|
Specimen Label: |
P0 -/- |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391013 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-02-20 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1753625 |
|
Stage: |
TS25 |
Assay Id: |
MGI:6391114 |
Age: |
embryonic day 17.5 |
Image: |
7 |
|
Specimen Label: |
XX WT |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391013 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-02-20 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1753625 |
|
Stage: |
TS25 |
Assay Id: |
MGI:6391114 |
Age: |
embryonic day 17.5 |
Image: |
7 |
|
Specimen Label: |
XX KO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391013 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-02-20 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1753625 |
|
Stage: |
TS25 |
Assay Id: |
MGI:6391114 |
Age: |
embryonic day 17.5 |
Image: |
7 |
|
Specimen Label: |
XY KO |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391013 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-02-20 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1753625 |
|
Stage: |
TS25 |
Assay Id: |
MGI:6391114 |
Age: |
embryonic day 17.5 |
Image: |
7 |
|
Specimen Label: |
XY WT |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6766380 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-10-12 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3514228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6766545 |
Age: |
postnatal week 12 |
|
|
Specimen Label: |
Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6766380 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-10-12 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3514228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6766545 |
Age: |
postnatal week 12 |
|
|
Specimen Label: |
Mutant |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464099 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1637022 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7464107 |
Age: |
embryonic day 14.5 |
Image: |
S2D SCAP+/+ |
|
Specimen Label: |
S2D SCAP+/+ |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7464099 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-18 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1637022 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:7464107 |
Age: |
embryonic day 14.5 |
Image: |
S2D SCAPfl/fl |
Note: |
Expression significantly upregulated in embryonic placenta compared to wild type. |
Specimen Label: |
S2D SCAPfl/fl |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391003 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-02-19 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3514228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6391014 |
Age: |
postnatal day 12 |
Image: |
4 P12 Female |
Note: |
A transient sex difference in the number of labeled cells was evident at P12. More cells were labeled in the female compared with the male. |
Specimen Label: |
4 P12 Female |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391003 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-02-19 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3514228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6391014 |
Age: |
postnatal day 12 |
Image: |
4 P12 Male |
Note: |
A transient sex difference in the number of labeled cells was evident at P12. More cells were labeled in the female compared with the male. |
Specimen Label: |
4 P12 Male |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391003 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-02-19 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3514228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6391014 |
Age: |
postnatal day 35 |
Image: |
4 P35 Female |
Note: |
There was no sex difference in the number of labeled cells at P35. |
Specimen Label: |
4 P35 Female |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391003 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-02-19 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3514228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6391014 |
Age: |
postnatal day 35 |
Image: |
4 P35 Male |
Note: |
There was no sex difference in the number of labeled cells at P35. |
Specimen Label: |
4 P35 Male |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2023-04-15 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3514228 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7461994 |
Age: |
postnatal adult |
|
Note: |
Signal is seen in the medial and caudal arcuate nucleus. |
Specimen Label: |
Not shown |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7469507 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-05 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3514226 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:7469649 |
Age: |
embryonic day 18.5 |
Image: |
7B/D |
|
Specimen Label: |
7B/D |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7469507 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-05 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3514226 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:7469649 |
Age: |
embryonic day 18.5 |
Image: |
7E/G |
|
Specimen Label: |
7E/G |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7469507 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3514224 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:7469649 |
Age: |
embryonic day 16.5 |
Image: |
7-2 |
|
Specimen Label: |
7-2 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7469507 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-05 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3514227 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7469649 |
Age: |
postnatal day 0 |
Image: |
8A male |
|
Specimen Label: |
8A male |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7469507 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-05 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3514227 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:7469649 |
Age: |
postnatal day 0 |
Image: |
8B female |
|
Specimen Label: |
8B female |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7284771 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-06-10 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753620 |
|
Stage: |
TS20 |
Assay Id: |
MGI:7284784 |
Age: |
embryonic day 12.5 |
Image: |
5A - E12.5 |
Note: |
No expression is seen in the presumptive arcuate nucleus. |
Specimen Label: |
5A - E12.5 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7284771 |
Assay Type: |
RNA in situ |
Annotation Date: |
2022-06-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:7284784 |
Age: |
embryonic day 15.5 |
Image: |
5A - E15.5 |
Note: |
Expression is seen in the presumptive arcuate nucleus. |
Specimen Label: |
5A - E15.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7469507 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-05-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753621 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:7469649 |
Age: |
embryonic day 13.5 |
Image: |
7-1 |
Note: |
Expression is seen in the arcuate nucleus. |
Specimen Label: |
7-1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391003 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-02-19 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1689621 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:6391014 |
Age: |
embryonic day 13.5 |
Image: |
1 E13 |
Note: |
Expression was detected in a few cells near the median eminence. |
Specimen Label: |
1 E13 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391003 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-02-19 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1689623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:6391014 |
Age: |
embryonic day 15.5 |
Image: |
1 E15 |
Note: |
The total number of expressing cells had greatly increased (from 30 cells/half brain to ~400 cells/half brain), although the distribution remained similar. |
Specimen Label: |
1 E15 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391003 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-02-19 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1689621 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:6391014 |
Age: |
embryonic day 13.5 |
Image: |
4 E13 Female |
Note: |
Expression was detected in a few cells near the median eminence. There was no sex difference in the number of expressing cells. |
Specimen Label: |
4 E13 Female |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391003 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-02-19 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689621 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:6391014 |
Age: |
embryonic day 13.5 |
Image: |
4 E13 Male |
Note: |
Expression was detected in a few cells near the median eminence. There was no sex difference in the number of expressing cells. |
Specimen Label: |
4 E13 Male |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391019 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2020-02-20 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3542125 |
Pattern: |
Regionally restricted |
Stage: |
TS25 |
Assay Id: |
MGI:6391106 |
Age: |
embryonic day 17.5 |
Image: |
3B |
Note: |
Expression was detected in the arcuate nucleus. Serial coronal sections from rostral to caudal indicated that expression extends over 800-1000 um. |
Specimen Label: |
3B |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391003 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-02-19 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3542125 |
Pattern: |
Regionally restricted |
Stage: |
TS25 |
Assay Id: |
MGI:6391014 |
Age: |
embryonic day 17.5 |
Image: |
3A |
Note: |
Expression was detected in the arcuate nucleus. Serial coronal sections from rostral to caudal indicated that expression extends over 800-1000 um. |
Specimen Label: |
3A |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6391003 |
Assay Type: |
RNA in situ |
Annotation Date: |
2020-02-19 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:3542125 |
Pattern: |
Regionally restricted |
Stage: |
TS25 |
Assay Id: |
MGI:6391014 |
Age: |
embryonic day 17.5 |
Image: |
4 E17 Female |
Note: |
Expression was detected in the arcuate nucleus. There was no sex difference in the number of expressing cells. |
Specimen Label: |
4 E17 Female |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|