|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 3295 for Kras

<< First    < Previous  |  Next >    Last >>
0.079s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Publication
29452147 | J:258663
 
First Author: Lin YK
Year: 2018
Journal: Cancer Lett
Title: Combination of Kras activation and PTEN deletion contributes to murine hepatopancreatic ductal malignancy.
Volume: 421
Pages: 161-169
•
•
•
•
•
Publication
32405640 | J:294932
 
First Author: Janardhan HP
Year: 2020
Journal: J Exp Med
Title: KRAS or BRAF mutations cause hepatic vascular cavernomas treatable with MAP2K-MAPK1 inhibition.
Volume: 217
Issue: 7
•
•
•
•
•
Publication
22232209 | J:184378
First Author: Collins MA
Year: 2012
Journal: J Clin Invest
Title: Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice.
Volume: 122
Issue: 2
Pages: 639-53
•
•
•
•
•
Publication
27032374 | J:254370
 
First Author: Ikenoue T
Year: 2016
Journal: Sci Rep
Title: A novel mouse model of intrahepatic cholangiocarcinoma induced by liver-specific Kras activation and Pten deletion.
Volume: 6
Pages: 23899
•
•
•
•
•
Publication
19208363 | J:148720
First Author: Trobridge P
Year: 2009
Journal: Gastroenterology
Title: TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway.
Volume: 136
Issue: 5
Pages: 1680-8.e7
•
•
•
•
•
Publication
20452353 | J:337198
First Author: Morton JP
Year: 2010
Journal: Gastroenterology
Title: LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest.
Volume: 139
Issue: 2
Pages: 586-97, 597.e1-6
•
•
•
•
•
Publication
31217166 | J:279036
First Author: Yoon C
Year: 2019
Journal: Mol Cancer Res
Title: KRAS Activation in Gastric Adenocarcinoma Stimulates Epithelial-to-Mesenchymal Transition to Cancer Stem-Like Cells and Promotes Metastasis.
Volume: 17
Issue: 9
Pages: 1945-1957
•
•
•
•
•
Publication
28653505 | J:247780
First Author: Fujimoto J
Year: 2017
Journal: Int J Cancer
Title: Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a.
Volume: 141
Issue: 8
Pages: 1589-1599
•
•
•
•
•
Publication
31766149 | J:289010
 
First Author: Maitra R
Year: 2019
Journal: Int J Mol Sci
Title: Development and Characterization of a Genetic Mouse Model of KRAS Mutated Colorectal Cancer.
Volume: 20
Issue: 22
•
•
•
•
•
Publication
24058630 | J:207342
First Author: Yang X
Year: 2013
Journal: PLoS One
Title: Simultaneous activation of Kras and inactivation of p53 induces soft tissue sarcoma and bladder urothelial hyperplasia.
Volume: 8
Issue: 9
Pages: e74809
•
•
•
•
•
Publication
19629168 | J:151781
First Author: Vincent DF
Year: 2009
Journal: PLoS Genet
Title: Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas.
Volume: 5
Issue: 7
Pages: e1000575
•
•
•
•
•
Publication
22577135 | J:188377
First Author: Ryu MJ
Year: 2012
Journal: J Biol Chem
Title: Oncogenic Kras expression in postmitotic neurons leads to S100A8-S100A9 protein overexpression and gliosis.
Volume: 287
Issue: 27
Pages: 22948-58
•
•
•
•
•
Publication
27550813 | J:243006
First Author: Zhong X
Year: 2016
Journal: Mol Cell Biol
Title: Suppression of MicroRNA 200 Family Expression by Oncogenic KRAS Activation Promotes Cell Survival and Epithelial-Mesenchymal Transition in KRAS-Driven Cancer.
Volume: 36
Issue: 21
Pages: 2742-2754
•
•
•
•
•
Publication
23703846 | J:320504
First Author: Bhusari S
Year: 2014
Journal: Toxicol Pathol
Title: Mutation spectra of Kras and Tp53 in urethral and lung neoplasms in B6C3F1 mice treated with 3,3',4,4'-tetrachloroazobenzene.
Volume: 42
Issue: 3
Pages: 555-64
•
•
•
•
•
Publication
27477280 | J:238981
First Author: Padanad MS
Year: 2016
Journal: Cell Rep
Title: Fatty Acid Oxidation Mediated by Acyl-CoA Synthetase Long Chain 3 Is Required for Mutant KRAS Lung Tumorigenesis.
Volume: 16
Issue: 6
Pages: 1614-1628
•
•
•
•
•
Publication
26837764 | J:231629
First Author: Thiem S
Year: 2016
Journal: Cancer Res
Title: Stomach-Specific Activation of Oncogenic KRAS and STAT3-Dependent Inflammation Cooperatively Promote Gastric Tumorigenesis in a Preclinical Model.
Volume: 76
Issue: 8
Pages: 2277-87
•
•
•
•
•
Publication
30142336 | J:309352
First Author: Ideno N
Year: 2018
Journal: Gastroenterology
Title: GNASR201C Induces Pancreatic Cystic Neoplasms in Mice That Express Activated KRAS by Inhibiting YAP1 Signaling.
Volume: 155
Issue: 5
Pages: 1593-1607.e12
•
•
•
•
•
Publication
24823639 | J:210592
First Author: McAllister F
Year: 2014
Journal: Cancer Cell
Title: Oncogenic Kras activates a hematopoietic-to-epithelial IL-17 signaling axis in preinvasive pancreatic neoplasia.
Volume: 25
Issue: 5
Pages: 621-37
•
•
•
•
•
Publication
20495549 | J:208978
First Author: Singh M
Year: 2010
Journal: Nat Biotechnol
Title: Assessing therapeutic responses in Kras mutant cancers using genetically engineered mouse models.
Volume: 28
Issue: 6
Pages: 585-93
•
•
•
•
•
Publication
23245996 | J:194363
First Author: Corcoran RB
Year: 2013
Journal: Cancer Cell
Title: Synthetic lethal interaction of combined BCL-XL and MEK inhibition promotes tumor regressions in KRAS mutant cancer models.
Volume: 23
Issue: 1
Pages: 121-8
•
•
•
•
•
Publication
24163374 | J:208914
First Author: Faber AC
Year: 2014
Journal: Cancer Discov
Title: mTOR inhibition specifically sensitizes colorectal cancers with KRAS or BRAF mutations to BCL-2/BCL-XL inhibition by suppressing MCL-1.
Volume: 4
Issue: 1
Pages: 42-52
•
•
•
•
•
Publication
23123965 | J:192269
First Author: Mukhopadhyay A
Year: 2013
Journal: Dev Biol
Title: Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development.
Volume: 373
Issue: 2
Pages: 373-82
•
•
•
•
•
Publication
24276238 | J:216266
First Author: Elsum IA
Year: 2014
Journal: Oncogene
Title: Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo.
Volume: 33
Issue: 48
Pages: 5523-33
•
•
•
•
•
Publication
23376846 | J:212382
First Author: Ray KC
Year: 2014
Journal: Oncogene
Title: Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia.
Volume: 33
Issue: 7
Pages: 823-31
•
•
•
•
•
Publication
30405152 | J:269632
First Author: Quan S
Year: 2018
Journal: Sci Rep
Title: Loss of Sirt2 increases and prolongs a caerulein-induced pancreatitis permissive phenotype and induces spontaneous oncogenic Kras mutations in mice.
Volume: 8
Issue: 1
Pages: 16501
•
•
•
•
•
Publication
14699048 | J:87429
First Author: Braun BS
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder.
Volume: 101
Issue: 2
Pages: 597-602
•
•
•
•
•
Publication
30956775 | J:298186
First Author: Baker SJ
Year: 2019
Journal: Oncotarget
Title: Rigosertib ameliorates the effects of oncogenic KRAS signaling in a murine model of myeloproliferative neoplasia.
Volume: 10
Issue: 20
Pages: 1932-1942
•
•
•
•
•
Publication
23454899 | J:200122
First Author: Molina-Arcas M
Year: 2013
Journal: Cancer Discov
Title: Coordinate direct input of both KRAS and IGF1 receptor to activation of PI3 kinase in KRAS-mutant lung cancer.
Volume: 3
Issue: 5
Pages: 548-63
•
•
•
•
•
Publication
23482563 | J:198390
First Author: Mills LD
Year: 2013
Journal: J Biol Chem
Title: Loss of the transcription factor GLI1 identifies a signaling network in the tumor microenvironment mediating KRAS oncogene-induced transformation.
Volume: 288
Issue: 17
Pages: 11786-94
•
•
•
•
•
Publication
30510993 | J:294540
First Author: Young CC
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: The Loss of ATRX Increases Susceptibility to Pancreatic Injury and Oncogenic KRAS in Female But Not Male Mice.
Volume: 7
Issue: 1
Pages: 93-113
•
•
•
•
•
Publication
22113502 | J:198619
First Author: Qiu W
Year: 2011
Journal: Oncotarget
Title: Disruption of p16 and activation of Kras in pancreas increase ductal adenocarcinoma formation and metastasis in vivo.
Volume: 2
Issue: 11
Pages: 862-73
•
•
•
•
•
Publication
23958541 | J:324563
First Author: Philip B
Year: 2013
Journal: Gastroenterology
Title: A high-fat diet activates oncogenic Kras and COX2 to induce development of pancreatic ductal adenocarcinoma in mice.
Volume: 145
Issue: 6
Pages: 1449-58
•
•
•
•
•
Publication
19966866 | J:160400
First Author: Liang MC
Year: 2010
Journal: Oncogene
Title: TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity.
Volume: 29
Issue: 11
Pages: 1588-97
•
•
•
•
•
Publication
19029981 | J:142254
First Author: Engelman JA
Year: 2008
Journal: Nat Med
Title: Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers.
Volume: 14
Issue: 12
Pages: 1351-6
•
•
•
•
•
Publication
25452273 | J:217379
First Author: Baer R
Year: 2014
Journal: Genes Dev
Title: Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α.
Volume: 28
Issue: 23
Pages: 2621-35
•
•
•
•
•
Publication
31352001 | J:290698
First Author: Luo Y
Year: 2019
Journal: Gastroenterology
Title: Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet.
Volume: 157
Issue: 5
Pages: 1413-1428.e11
•
•
•
•
•
Publication
30585163 | J:295089
First Author: Choi E
Year: 2019
Journal: Cell Mol Gastroenterol Hepatol
Title: Active Kras Expression in Gastric Isthmal Progenitor Cells Induces Foveolar Hyperplasia but Not Metaplasia.
Volume: 7
Issue: 1
Pages: 251-253.e1
•
•
•
•
•
Publication
29844011 | J:264756
First Author: Melo-Cardenas J
Year: 2018
Journal: Blood
Title: USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism.
Volume: 132
Issue: 4
Pages: 423-434
•
•
•
•
•
Publication
30168144 | J:273794
First Author: Kinoshita H
Year: 2019
Journal: J Pathol
Title: Three types of metaplasia model through Kras activation, Pten deletion, or Cdh1 deletion in the gastric epithelium.
Volume: 247
Issue: 1
Pages: 35-47
•
•
•
•
•
Publication
26973247 | J:230792
First Author: Zhang L
Year: 2016
Journal: Oncogene
Title: Effects of Kras activation and Pten deletion alone or in combination on MUC1 biology and epithelial-to-mesenchymal transition in ovarian cancer.
Volume: 35
Issue: 38
Pages: 5010-20
•
•
•
•
•
Publication
37779142 | J:342131
First Author: Shin DH
Year: 2023
Journal: Exp Mol Med
Title: Oncogenic KRAS mutation confers chemoresistance by upregulating SIRT1 in non-small cell lung cancer.
Volume: 55
Issue: 10
Pages: 2220-2237
•
•
•
•
•
Publication
27439864 | J:235137
First Author: Metz HE
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Insulin receptor substrate-1 deficiency drives a proinflammatory phenotype in KRAS mutant lung adenocarcinoma.
Volume: 113
Issue: 31
Pages: 8795-800
•
•
•
•
•
Publication
23887057 | J:202529
First Author: Shen R
Year: 2013
Journal: Cancer Lett
Title: The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models.
Volume: 339
Issue: 1
Pages: 135-43
•
•
•
•
•
Publication
28032649 | J:239543
First Author: Tang FH
Year: 2017
Journal: Int J Cancer
Title: KRAS mutation coupled with p53 loss is sufficient to induce ovarian carcinosarcomas in mice.
Volume: 140
Issue: 8
Pages: 1860-1869
•
•
•
•
•
Publication
36614194 | J:332519
 
First Author: Smith JP
Year: 2023
Journal: Int J Mol Sci
Title: Target-Specific Nanoparticle Polyplex Down-Regulates Mutant Kras to Prevent Pancreatic Carcinogenesis and Halt Tumor Progression.
Volume: 24
Issue: 1
•
•
•
•
•
Publication
36543126 | J:332394
First Author: Tan M
Year: 2022
Journal: Cell Rep
Title: The Sag-Shoc2 axis regulates conversion of mPanINs to cystic lesions in Kras pancreatic tumor model.
Volume: 41
Issue: 12
Pages: 111837
•
•
•
•
•
Publication
33302159 | J:327400
 
First Author: Kobayashi K
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Functional dissection of the KRAS G12C mutation by comparison among multiple oncogenic driver mutations in a lung cancer cell line model.
Volume: 534
Pages: 1-7
•
•
•
•
•
Publication
26542681 | J:228077
First Author: Yeddula N
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Screening for tumor suppressors: Loss of ephrin receptor A2 cooperates with oncogenic KRas in promoting lung adenocarcinoma.
Volume: 112
Issue: 47
Pages: E6476-85
•
•
•
•
•
Publication
32918044 | J:306527
First Author: Junco JJ
Year: 2021
Journal: Leukemia
Title: An Mb1-Cre-driven oncogenic Kras mutation results in a mouse model of T-acute lymphoblastic leukemia/lymphoma with short latency and high penetrance.
Volume: 35
Issue: 6
Pages: 1777-1781
•
•
•
•
•
Publication
29273451 | J:273682
First Author: Kopp JL
Year: 2018
Journal: Gastroenterology
Title: Loss of Pten and Activation of Kras Synergistically Induce Formation of Intraductal Papillary Mucinous Neoplasia From Pancreatic Ductal Cells in Mice.
Volume: 154
Issue: 5
Pages: 1509-1523.e5
•
•
•
•
•
Publication
24944064 | J:216001
First Author: Knab LM
Year: 2014
Journal: Mol Cancer Res
Title: Snail cooperates with Kras G12D in vivo to increase stem cell factor and enhance mast cell infiltration.
Volume: 12
Issue: 10
Pages: 1440-8
•
•
•
•
•
Publication
32552404 | J:312482
First Author: Fish JE
Year: 2020
Journal: Circ Res
Title: Somatic Gain of KRAS Function in the Endothelium Is Sufficient to Cause Vascular Malformations That Require MEK but Not PI3K Signaling.
Volume: 127
Issue: 6
Pages: 727-743
•
•
•
•
•
Publication
28760854 | J:245682
First Author: Till JE
Year: 2017
Journal: Cancer Res
Title: Oncogenic KRAS and p53 Loss Drive Gastric Tumorigenesis in Mice That Can Be Attenuated by E-Cadherin Expression.
Volume: 77
Issue: 19
Pages: 5349-5359
•
•
•
•
•
Publication
35983994 | J:327876
   
First Author: Pribluda A
Year: 2022
Journal: Elife
Title: EHMT2 methyltransferase governs cell identity in the lung and is required for KRAS G12D tumor development and propagation.
Volume: 11
•
•
•
•
•
Publication
22976127 | J:196802
First Author: Du J
Year: 2013
Journal: Leukemia
Title: Loss of CD44 attenuates aberrant GM-CSF signaling in Kras G12D hematopoietic progenitor/precursor cells and prolongs the survival of diseased animals.
Volume: 27
Issue: 3
Pages: 754-7
•
•
•
•
•
Publication
25246276 | J:273044
First Author: Zhu X
Year: 2014
Journal: Neoplasia
Title: Synergistic signaling of KRAS and thyroid hormone receptor β mutants promotes undifferentiated thyroid cancer through MYC up-regulation.
Volume: 16
Issue: 9
Pages: 757-69
•
•
•
•
•
Publication
20179099 | J:159024
First Author: Ichise T
Year: 2010
Journal: Development
Title: H-, N- and Kras cooperatively regulate lymphatic vessel growth by modulating VEGFR3 expression in lymphatic endothelial cells in mice.
Volume: 137
Issue: 6
Pages: 1003-13
•
•
•
•
•
Publication
33882289 | J:308498
First Author: Wang X
Year: 2021
Journal: Am J Pathol
Title: Vaginal Squamous Cell Carcinoma Develops in Mice with Conditional Arid1a Loss and Gain of Oncogenic Kras Driven by Progesterone Receptor Cre.
Volume: 191
Issue: 7
Pages: 1281-1291
•
•
•
•
•
Publication
17114585 | J:116129
First Author: Ijichi H
Year: 2006
Journal: Genes Dev
Title: Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression.
Volume: 20
Issue: 22
Pages: 3147-60
•
•
•
•
•
Publication
25078979 | J:218996
First Author: Tirodkar TS
Year: 2014
Journal: PLoS One
Title: MUC1 positive, Kras and Pten driven mouse gynecologic tumors replicate human tumors and vary in survival and nuclear grade based on anatomical location.
Volume: 9
Issue: 7
Pages: e102409
•
•
•
•
•
Publication
19679546 | J:151931
First Author: Fan HY
Year: 2009
Journal: Cancer Res
Title: Cell type-specific targeted mutations of Kras and Pten document proliferation arrest in granulosa cells versus oncogenic insult to ovarian surface epithelial cells.
Volume: 69
Issue: 16
Pages: 6463-72
•
•
•
•
•
Publication
19028870 | J:142189
First Author: Habbe N
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice.
Volume: 105
Issue: 48
Pages: 18913-8
•
•
•
•
•
Publication
21860425 | J:186144
First Author: Richards JS
Year: 2012
Journal: Oncogene
Title: Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis.
Volume: 31
Issue: 12
Pages: 1504-20
•
•
•
•
•
Publication
28099846 | J:254560
First Author: Nagaraj AS
Year: 2017
Journal: Cell Rep
Title: Cell of Origin Links Histotype Spectrum to Immune Microenvironment Diversity in Non-small-Cell Lung Cancer Driven by Mutant Kras and Loss of Lkb1.
Volume: 18
Issue: 3
Pages: 673-684
•
•
•
•
•
Publication
31397499 | J:298216
First Author: Xu D
Year: 2019
Journal: Mol Carcinog
Title: Inhibition of mutant Kras and p53-driven pancreatic carcinogenesis by atorvastatin: Mainly via targeting of the farnesylated DNAJA1 in chaperoning mutant p53.
Volume: 58
Issue: 11
Pages: 2052-2064
•
•
•
•
•
Publication
28289141 | J:242160
First Author: Boutin AT
Year: 2017
Journal: Genes Dev
Title: Oncogenic Kras drives invasion and maintains metastases in colorectal cancer.
Volume: 31
Issue: 4
Pages: 370-382
•
•
•
•
•
Gene
108712520 | kras.S
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Publication
30377195 | J:269361
First Author: You X
Year: 2018
Journal: Blood
Title: Unique dependence on Sos1 in Kras G12D -induced leukemogenesis.
Volume: 132
Issue: 24
Pages: 2575-2579
•
•
•
•
•
Protein
P32883
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
•
•
•
•
•
Protein
P32883-2
Organism: Mus musculus/domesticus
Length: 188  
Fragment?: false
•
•
•
•
•
Protein
E9Q8V2
Organism: Mus musculus/domesticus
Length: 40  
Fragment?: false
•
•
•
•
•
Protein
B2KGV5
Organism: Mus musculus/domesticus
Length: 34  
Fragment?: true
•
•
•
•
•
Protein
A0A0N4SVY1
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: false
•
•
•
•
•
Protein
Q0VDV7
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
•
•
•
•
•
Allele
Tg(Fabp2-KRAS*Val12)#Jig | MGI:3531319
Name: transgene insertion #, Jeffrey I Gordon
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
•
•
•
•
•
Publication
28652249 | J:245582
First Author: Richer AL
Year: 2017
Journal: Cancer Res
Title: WEE1 Kinase Inhibitor AZD1775 Has Preclinical Efficacy in LKB1-Deficient Non-Small Cell Lung Cancer.
Volume: 77
Issue: 17
Pages: 4663-4672
•
•
•
•
•
Publication
29871934 | J:264249
First Author: Hill MA
Year: 2018
Journal: Cancer Res
Title: Kras and Tp53 Mutations Cause Cholangiocyte- and Hepatocyte-Derived Cholangiocarcinoma.
Volume: 78
Issue: 16
Pages: 4445-4451
•
•
•
•
•
Publication
32792368 | J:299292
First Author: Zafra MP
Year: 2020
Journal: Cancer Discov
Title: An In Vivo Kras Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants.
Volume: 10
Issue: 11
Pages: 1654-1671
•
•
•
•
•
Publication
33268505 | J:305012
 
First Author: Chung WC
Year: 2021
Journal: Life Sci Alliance
Title: Loss of Jag1 cooperates with oncogenic Kras to induce pancreatic cystic neoplasms.
Volume: 4
Issue: 2
•
•
•
•
•
Publication
33839689 | J:308176
First Author: Kim MP
Year: 2021
Journal: Cancer Discov
Title: Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis.
Volume: 11
Issue: 8
Pages: 2094-2111
•
•
•
•
•
Publication
29203670 | J:256758
First Author: Chung WJ
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Kras mutant genetically engineered mouse models of human cancers are genomically heterogeneous.
Volume: 114
Issue: 51
Pages: E10947-E10955
•
•
•
•
•
HT Experiment
GSE243258 | KRAS is required for placenta development
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
•
•
•
•
•
Publication
25071166 | J:213706
First Author: Amelio AL
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvement.
Volume: 111
Issue: 32
Pages: E3260-8
•
•
•
•
•
Publication
20541700 | J:160885
First Author: Carretero J
Year: 2010
Journal: Cancer Cell
Title: Integrative genomic and proteomic analyses identify targets for Lkb1-deficient metastatic lung tumors.
Volume: 17
Issue: 6
Pages: 547-59
•
•
•
•
•
Publication
28387316 | J:253496
 
First Author: Zhang H
Year: 2017
Journal: Nat Commun
Title: Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2.
Volume: 8
Pages: 14922
•
•
•
•
•
Publication
23597566 | J:197037
First Author: Xiao Z
Year: 2013
Journal: Cancer Cell
Title: The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas.
Volume: 23
Issue: 4
Pages: 527-40
•
•
•
•
•
Publication
34257283 | J:307920
First Author: Chen WC
Year: 2021
Journal: Nat Commun
Title: Targeting KRAS4A splicing through the RBM39/DCAF15 pathway inhibits cancer stem cells.
Volume: 12
Issue: 1
Pages: 4288
•
•
•
•
•
Publication
17676035 | J:124682
First Author: Ji H
Year: 2007
Journal: Nature
Title: LKB1 modulates lung cancer differentiation and metastasis.
Volume: 448
Issue: 7155
Pages: 807-10
•
•
•
•
•
Publication
30333301 | J:286967
 
First Author: Van Mater D
Year: 2018
Journal: JCI Insight
Title: Injury promotes sarcoma development in a genetically and temporally restricted manner.
Volume: 3
Issue: 20
•
•
•
•
•
Publication
23751876 | J:202152
First Author: Sponziello M
Year: 2013
Journal: Endocrinology
Title: Molecular differences between human thyroid follicular adenoma and carcinoma revealed by analysis of a murine model of thyroid cancer.
Volume: 154
Issue: 9
Pages: 3043-53
•
•
•
•
•
Publication
26458870 | J:239870
First Author: Hernández-Porras I
Year: 2015
Journal: Rare Dis
Title: The impact of the genetic background in the Noonan syndrome phenotype induced by K-Ras(V14I).
Volume: 3
Issue: 1
Pages: e1045169
•
•
•
•
•
Publication
29055016 | J:252305
First Author: Orlacchio A
Year: 2017
Journal: Cancer Res
Title: SGK1 Is a Critical Component of an AKT-Independent Pathway Essential for PI3K-Mediated Tumor Development and Maintenance.
Volume: 77
Issue: 24
Pages: 6914-6926
•
•
•
•
•
Publication
24794706 | J:210599
First Author: Xu C
Year: 2014
Journal: Cancer Cell
Title: Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.
Volume: 25
Issue: 5
Pages: 590-604
•
•
•
•
•
Publication
32109375 | J:285842
First Author: Salvador-Barbero B
Year: 2020
Journal: Cancer Cell
Title: CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma.
Volume: 37
Issue: 3
Pages: 340-353.e6
•
•
•
•
•
Publication
32066953 | J:292988
First Author: Wang H
Year: 2020
Journal: Nat Immunol
Title: CD36-mediated metabolic adaptation supports regulatory T cell survival and function in tumors.
Volume: 21
Issue: 3
Pages: 298-308
•
•
•
•
•
Publication
27799657 | J:241316
First Author: Kottakis F
Year: 2016
Journal: Nature
Title: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
Volume: 539
Issue: 7629
Pages: 390-395
•
•
•
•
•
Publication
25854920 | J:221857
First Author: Biran A
Year: 2015
Journal: Genes Dev
Title: Senescent cells communicate via intercellular protein transfer.
Volume: 29
Issue: 8
Pages: 791-802
•
•
•
•
•
Publication
12727809 | J:83092
First Author: Brembeck FH
Year: 2003
Journal: Cancer Res
Title: The mutant K-ras oncogene causes pancreatic periductal lymphocytic infiltration and gastric mucous neck cell hyperplasia in transgenic mice.
Volume: 63
Issue: 9
Pages: 2005-9
•
•
•
•
•
Publication
34331774 | J:311000
First Author: Rosigkeit S
Year: 2021
Journal: Int J Cancer
Title: Definitive evidence for Club cells as progenitors for mutant Kras/Trp53-deficient lung cancer.
Volume: 149
Issue: 9
Pages: 1670-1682
•
•
•
•
•
Publication
38910965 | J:350175
 
First Author: Weiss EM
Year: 2024
Journal: Front Cell Neurosci
Title: Developmental effect of RASopathy mutations on neuronal network activity on a chip.
Volume: 18
Pages: 1388409
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom