Type |
Details |
Score |
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
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•
•
•
•
•
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Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
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•
•
•
•
•
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Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
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•
•
•
•
•
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Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
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•
•
•
•
•
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Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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•
•
•
•
•
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Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
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•
•
•
•
•
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Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
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•
•
•
•
•
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Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
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•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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|
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•
•
•
•
•
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
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•
•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
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|
|
•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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|
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•
•
•
•
•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
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|
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•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
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|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
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|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The lysosome associated protein transmembrane (LAPTM) family is comprised of three members: LAPTM5, LAPTM4a and LAPTM4b; they are lysosome-associated transmembrane proteins, found in mammals, insects and nematodes. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
233
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
308
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
197
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Hogue DL |
Year: |
2002 |
Journal: |
Biochem J |
Title: |
Lysosome-associated protein transmembrane 4 alpha (LAPTM4 alpha) requires two tandemly arranged tyrosine-based signals for sorting to lysosomes. |
Volume: |
365 |
Issue: |
Pt 3 |
Pages: |
721-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cabrita MA |
Year: |
1999 |
Journal: |
Cancer Res |
Title: |
Mouse transporter protein, a membrane protein that regulates cellular multidrug resistance, is localized to lysosomes. |
Volume: |
59 |
Issue: |
19 |
Pages: |
4890-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Inoue J |
Year: |
2009 |
Journal: |
PLoS One |
Title: |
Lysosomal-associated protein multispanning transmembrane 5 gene (LAPTM5) is associated with spontaneous regression of neuroblastomas. |
Volume: |
4 |
Issue: |
9 |
Pages: |
e7099 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The lysosome associated protein transmembrane (LAPTM) family is comprised of three members: LAPTM5, LAPTM4a and LAPTM4b; they are lysosome-associated transmembrane proteins, found in mammals, insects and nematodes.This entry represents LAPTM4 alpha (LAPTM4A) and LAPTM45. LAPTM4A regulates the intracellular compartmentalisation of amphipathic solutes and possibly the sensitivity of cells toward anthracyclines, antibiotics, ionophores, nucleobases and organic cations [, ]. LAPTM5 may have functional role during embryogenesis and in adult hematopoietic cells []. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
227
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
227
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
89
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
267
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
263
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
231
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
173
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
241
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
264
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
86
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
107
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
44
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
159
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Y |
Year: |
2007 |
Journal: |
Ann Oncol |
Title: |
Relationship between LAPTM4B gene polymorphism and susceptibility of gastric cancer. |
Volume: |
18 |
Issue: |
2 |
Pages: |
311-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shao GZ |
Year: |
2003 |
Journal: |
Oncogene |
Title: |
Molecular cloning and characterization of LAPTM4B, a novel gene upregulated in hepatocellular carcinoma. |
Volume: |
22 |
Issue: |
32 |
Pages: |
5060-9 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The lysosome associated protein transmembrane (LAPTM) family is comprised of three members: LAPTM5, LAPTM4a and LAPTM4b; they are lysosome-associated transmembrane proteins, found in mammals, insects and nematodes.This entry represents LAPTM4 beta (LAPTM4B). Overexpression of LAPTM4B has been show to be involved in carcinogenesis [], and polymorphisms in the gene have been asssociated with an increased susceptibility to gastric cancer []. In normal cells, LAPTM4B may play a role in the regulation of cell proliferation and survival []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Ouchida R |
Year: |
2010 |
Journal: |
J Immunol |
Title: |
A role for lysosomal-associated protein transmembrane 5 in the negative regulation of surface B cell receptor levels and B cell activation. |
Volume: |
185 |
Issue: |
1 |
Pages: |
294-301 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ouchida R |
Year: |
2008 |
Journal: |
Immunity |
Title: |
A lysosomal protein negatively regulates surface T cell antigen receptor expression by promoting CD3zeta-chain degradation. |
Volume: |
29 |
Issue: |
1 |
Pages: |
33-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Glowacka WK |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
LAPTM5 protein is a positive regulator of proinflammatory signaling pathways in macrophages. |
Volume: |
287 |
Issue: |
33 |
Pages: |
27691-702 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pak Y |
Year: |
2006 |
Journal: |
J Cell Biol |
Title: |
Transport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitination. |
Volume: |
175 |
Issue: |
4 |
Pages: |
631-45 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The lysosome associated protein transmembrane (LAPTM) family is comprised of three members: LAPTM5, LAPTM4a and LAPTM4b; they are lysosome-associated transmembrane proteins, found in mammals, insects and nematodes.This entry represents LAPTM5, which is a lysosomal protein expressed in cells of lymphoid and myeloid origin. LAPTM5 trafficking from the Golgi to the lysosome requires its association with the ubiquitin ligase Nedd4 and the clathrin adaptor GGA3 []. LAPTM5 negatively regulates T and B cell receptor signaling by directly interacting with these receptors and mediating their down-regulation [, ]. It is also a positive regulator of NF-kB and MAPK signaling allowing efficient proinflammatory cytokine production in response to macrophage activation []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2000 |
Journal: |
Genome Res |
Title: |
Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. |
Volume: |
10 |
Issue: |
10 |
Pages: |
1617-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
1999 |
Journal: |
Methods Enzymol |
Title: |
High-efficiency full-length cDNA cloning. |
Volume: |
303 |
|
Pages: |
19-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shibata K |
Year: |
2000 |
Journal: |
Genome Res |
Title: |
RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. |
Volume: |
10 |
Issue: |
11 |
Pages: |
1757-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Katayama S |
Year: |
2005 |
Journal: |
Science |
Title: |
Antisense transcription in the mammalian transcriptome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1564-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|