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Search results 101 to 200 out of 244 for Lats1

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Type Details Score
Publication
35768444 | J:326521
First Author: Vittoria MA
Year: 2022
Journal: Nat Commun
Title: Inactivation of the Hippo tumor suppressor pathway promotes melanoma.
Volume: 13
Issue: 1
Pages: 3732
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Publication
39173637 | J:355644
First Author: Nie L
Year: 2024
Journal: Mol Cell
Title: Consecutive palmitoylation and phosphorylation orchestrates NLRP3 membrane trafficking and inflammasome activation.
Volume: 84
Issue: 17
Pages: 3336-3353.e7
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Publication
36229481 | J:353711
First Author: Shen H
Year: 2022
Journal: Nat Commun
Title: The Hippo pathway links adipocyte plasticity to adipose tissue fibrosis.
Volume: 13
Issue: 1
Pages: 6030
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Publication
36395225 | J:331498
First Author: Kowalczyk W
Year: 2022
Journal: Science
Title: Hippo signaling instructs ectopic but not normal organ growth.
Volume: 378
Issue: 6621
Pages: eabg3679
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Publication
32994166 | J:300520
 
First Author: Vanyai HK
Year: 2020
Journal: Development
Title: Control of skeletal morphogenesis by the Hippo-YAP/TAZ pathway.
Volume: 147
Issue: 21
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Publication
29438698 | J:257766
First Author: Wu LMN
Year: 2018
Journal: Cancer Cell
Title: Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis.
Volume: 33
Issue: 2
Pages: 292-308.e7
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Publication
28115535 | J:270351
First Author: Kuroda M
Year: 2017
Journal: J Cell Sci
Title: Vinculin promotes nuclear localization of TAZ to inhibit ECM stiffness-dependent differentiation into adipocytes.
Volume: 130
Issue: 5
Pages: 989-1002
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Publication
26503053 | J:226759
First Author: Gregorieff A
Year: 2015
Journal: Nature
Title: Yap-dependent reprogramming of Lgr5(+) stem cells drives intestinal regeneration and cancer.
Volume: 526
Issue: 7575
Pages: 715-8
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Publication
26109051 | J:223215
First Author: Chen Q
Year: 2015
Journal: Genes Dev
Title: Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP.
Volume: 29
Issue: 12
Pages: 1285-97
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Publication
31754005 | J:287851
First Author: Moya IM
Year: 2019
Journal: Science
Title: Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice.
Volume: 366
Issue: 6468
Pages: 1029-1034
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Publication
31474569 | J:279351
First Author: Zhang L
Year: 2019
Journal: Cancer Cell
Title: Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse.
Volume: 36
Issue: 3
Pages: 302-318.e7
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Publication
23644383 | J:198940
First Author: Kim M
Year: 2013
Journal: EMBO J
Title: cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes.
Volume: 32
Issue: 11
Pages: 1543-55
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Publication
31801083 | J:296787
First Author: Li H
Year: 2019
Journal: Cell Rep
Title: YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression.
Volume: 29
Issue: 10
Pages: 3200-3211.e4
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Publication
31513574 | J:279504
First Author: Liu J
Year: 2019
Journal: PLoS Biol
Title: Activation of the intrinsic fibroinflammatory program in adult pancreatic acinar cells triggered by Hippo signaling disruption.
Volume: 17
Issue: 9
Pages: e3000418
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Publication
32341094 | J:288310
First Author: Rudolf MA
Year: 2020
Journal: J Neurosci
Title: YAP Mediates Hair Cell Regeneration in Balance Organs of Chickens, But LATS Kinases Suppress Its Activity in Mice.
Volume: 40
Issue: 20
Pages: 3915-3932
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Publication
24255096 | J:206316
First Author: Heallen T
Year: 2013
Journal: Development
Title: Hippo signaling impedes adult heart regeneration.
Volume: 140
Issue: 23
Pages: 4683-90
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Publication
31019301 | J:283362
First Author: Ayyaz A
Year: 2019
Journal: Nature
Title: Single-cell transcriptomes of the regenerating intestine reveal a revival stem cell.
Volume: 569
Issue: 7754
Pages: 121-125
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Publication
19289085 | J:147050
First Author: Nishioka N
Year: 2009
Journal: Dev Cell
Title: The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass.
Volume: 16
Issue: 3
Pages: 398-410
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Publication
32259481 | J:305872
First Author: Li Q
Year: 2020
Journal: Cell Stem Cell
Title: Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription.
Volume: 26
Issue: 5
Pages: 675-692.e8
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Publication
28973878 | J:280139
First Author: Sakabe M
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: YAP/TAZ-CDC42 signaling regulates vascular tip cell migration.
Volume: 114
Issue: 41
Pages: 10918-10923
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Publication
29669762 | J:262561
First Author: Choi W
Year: 2018
Journal: Cancer Res
Title: YAP/TAZ Initiates Gastric Tumorigenesis via Upregulation of MYC.
Volume: 78
Issue: 12
Pages: 3306-3320
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Publication
35191398 | J:330299
 
First Author: He X
Year: 2022
Journal: JCI Insight
Title: Myofibroblast YAP/TAZ activation is a key step in organ fibrogenesis.
Volume: 7
Issue: 4
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Publication
32796823 | J:294834
First Author: Hong SP
Year: 2020
Journal: Nat Commun
Title: Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi.
Volume: 11
Issue: 1
Pages: 4102
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Publication
30582452 | J:289355
First Author: Cho H
Year: 2019
Journal: Circ Res
Title: YAP and TAZ Negatively Regulate Prox1 During Developmental and Pathologic Lymphangiogenesis.
Volume: 124
Issue: 2
Pages: 225-242
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Publication
28805663 | J:242892
First Author: Kim J
Year: 2017
Journal: J Clin Invest
Title: YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation.
Volume: 127
Issue: 9
Pages: 3441-3461
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Publication
22187428 | J:182447
First Author: Jiang Z
Year: 2012
Journal: J Biol Chem
Title: Trinucleotide repeat containing 6a (Tnrc6a)-mediated microRNA function is required for development of yolk sac endoderm.
Volume: 287
Issue: 8
Pages: 5979-87
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Publication
32960816 | J:306797
 
First Author: Chen Z
Year: 2020
Journal: JCI Insight
Title: Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling.
Volume: 5
Issue: 20
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Publication
32289155 | J:288638
 
First Author: Raynor JL
Year: 2020
Journal: J Exp Med
Title: Hippo/Mst signaling coordinates cellular quiescence with terminal maturation in iNKT cell development and fate decisions.
Volume: 217
Issue: 6
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Publication
30348677 | J:269990
First Author: Chen Z
Year: 2019
Journal: Cancer Discov
Title: Spatiotemporal Loss of NF1 in Schwann Cell Lineage Leads to Different Types of Cutaneous Neurofibroma Susceptible to Modification by the Hippo Pathway.
Volume: 9
Issue: 1
Pages: 114-129
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Publication
32482884 | J:290788
First Author: Gnedeva K
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal.
Volume: 117
Issue: 24
Pages: 13552-13561
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Publication
36149942 | J:339188
First Author: Cui Y
Year: 2022
Journal: Sci Immunol
Title: A Stk4-Foxp3-NF-κB p65 transcriptional complex promotes T(reg) cell activation and homeostasis.
Volume: 7
Issue: 75
Pages: eabl8357
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Publication
27160901 | J:235463
First Author: Singh A
Year: 2016
Journal: Cell Rep
Title: Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development.
Volume: 15
Issue: 7
Pages: 1384-1393
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Publication
36283963 | J:333189
First Author: Nambiar SM
Year: 2023
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Maternal hepatocytes heterogeneously and dynamically exhibit developmental phenotypes partially via yes-associated protein 1 during pregnancy.
Volume: 324
Issue: 1
Pages: G38-G50
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Publication
28486106 | J:242576
First Author: Zhang S
Year: 2017
Journal: Cancer Cell
Title: Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2.
Volume: 31
Issue: 5
Pages: 669-684.e7
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Publication
27912060 | J:238063
First Author: Moroishi T
Year: 2016
Journal: Cell
Title: The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity.
Volume: 167
Issue: 6
Pages: 1525-1539.e17
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Publication
20643348 | J:162628
First Author: Zhang N
Year: 2010
Journal: Dev Cell
Title: The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals.
Volume: 19
Issue: 1
Pages: 27-38
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Publication
23824537 | J:199456
First Author: Lorthongpanich C
Year: 2013
Journal: Genes Dev
Title: Temporal reduction of LATS kinases in the early preimplantation embryo prevents ICM lineage differentiation.
Volume: 27
Issue: 13
Pages: 1441-6
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Publication
29274472 | J:320195
 
First Author: Liu B
Year: 2018
Journal: Int J Biochem Cell Biol
Title: Protein phosphatase 2ACα gene knock-out results in cortical atrophy through activating hippo cascade in neuronal progenitor cells.
Volume: 95
Pages: 53-62
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Publication
28087714 | J:238700
First Author: Kwan J
Year: 2016
Journal: Genes Dev
Title: DLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2.
Volume: 30
Issue: 24
Pages: 2696-2709
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Publication
18369314 | J:134270
First Author: Lee JH
Year: 2008
Journal: EMBO J
Title: A crucial role of WW45 in developing epithelial tissues in the mouse.
Volume: 27
Issue: 8
Pages: 1231-42
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Publication
32730753 | J:306079
First Author: Cheung P
Year: 2020
Journal: Cell Stem Cell
Title: Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer.
Volume: 27
Issue: 4
Pages: 590-604.e9
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Publication
34478649 | J:310907
First Author: Nacarino-Palma A
Year: 2021
Journal: Stem Cell Reports
Title: The aryl hydrocarbon receptor promotes differentiation during mouse preimplantational embryo development.
Volume: 16
Issue: 9
Pages: 2351-2363
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Publication
28457749 | J:253651
First Author: Hu JK
Year: 2017
Journal: Cell Stem Cell
Title: An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice.
Volume: 21
Issue: 1
Pages: 91-106.e6
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Publication
26235047 | J:239794
First Author: Szymaniak AD
Year: 2015
Journal: Dev Cell
Title: Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap.
Volume: 34
Issue: 3
Pages: 283-96
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Publication
21303848 | J:169135
First Author: Mao Y
Year: 2011
Journal: Development
Title: Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development.
Volume: 138
Issue: 5
Pages: 947-57
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Publication
29249622 | J:253963
First Author: Moon KH
Year: 2018
Journal: Dev Cell
Title: Differential Expression of NF2 in Neuroepithelial Compartments Is Necessary for Mammalian Eye Development.
Volume: 44
Issue: 1
Pages: 13-28.e3
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Publication
27405641 | J:240835
 
First Author: Li CY
Year: 2016
Journal: Nat Commun
Title: αE-catenin inhibits YAP/TAZ activity to regulate signalling centre formation during tooth development.
Volume: 7
Pages: 12133
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Publication
30523785 | J:272393
First Author: Lavado A
Year: 2018
Journal: Dev Cell
Title: The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number.
Volume: 47
Issue: 5
Pages: 576-591.e8
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Publication
31980640 | J:283927
First Author: Choi SY
Year: 2020
Journal: Nat Commun
Title: YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells.
Volume: 11
Issue: 1
Pages: 519
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Publication
23071096 | J:192856
First Author: George NM
Year: 2012
Journal: Mol Cell Biol
Title: Hippo signaling regulates pancreas development through inactivation of Yap.
Volume: 32
Issue: 24
Pages: 5116-28
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Publication
25912685 | J:224948
First Author: Lin C
Year: 2015
Journal: Dev Biol
Title: A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth.
Volume: 403
Issue: 1
Pages: 101-13
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Publication
30912742 | J:274694
   
First Author: Lodge EJ
Year: 2019
Journal: Elife
Title: Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade.
Volume: 8
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Publication
19786569 | J:155001
First Author: Oh S
Year: 2009
Journal: Mol Cell Biol
Title: Crucial role for Mst1 and Mst2 kinases in early embryonic development of the mouse.
Volume: 29
Issue: 23
Pages: 6309-20
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Publication
27480037 | J:241275
 
First Author: Reginensi A
Year: 2016
Journal: Nat Commun
Title: A critical role for NF2 and the Hippo pathway in branching morphogenesis.
Volume: 7
Pages: 12309
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Publication
29632206 | J:261328
First Author: Zou J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Neddylation mediates ventricular chamber maturation through repression of Hippo signaling.
Volume: 115
Issue: 17
Pages: E4101-E4110
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Publication
35918150 | J:330505
     
First Author: Drake KA
Year: 2022
Journal: J Am Soc Nephrol
Title: Transcription Factors YAP/TAZ and SRF Cooperate To Specify Renal Myofibroblasts in the Developing Mouse Kidney.
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Publication
28943241 | J:245870
First Author: Cotton JL
Year: 2017
Journal: Dev Cell
Title: YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal Mesenchyme.
Volume: 43
Issue: 1
Pages: 35-47.e4
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Publication
23620511 | J:197340
First Author: Chung C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Hippo-Foxa2 signaling pathway plays a role in peripheral lung maturation and surfactant homeostasis.
Volume: 110
Issue: 19
Pages: 7732-7
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Publication
15031102 | J:92177
First Author: Powles N
Year: 2004
Journal: Dev Biol
Title: Identification and analysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridization.
Volume: 268
Issue: 1
Pages: 24-38
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Publication
31323030 | J:279716
First Author: Braitsch CM
Year: 2019
Journal: PLoS Biol
Title: LATS1/2 suppress NFκB and aberrant EMT initiation to permit pancreatic progenitor differentiation.
Volume: 17
Issue: 7
Pages: e3000382
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:101977
     
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: Serine/threonine-protein kinase LATS1
Type: chain
End: 1129
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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