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Search results 101 to 117 out of 117 for Leo1

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0.018s

Type

Details

Score

Publication

24385927 | -

First Author:	Mbogning J
Year:	2013
Journal:	PLoS Genet
Title:	The PAF complex and Prf1/Rtf1 delineate distinct Cdk9-dependent pathways regulating transcription elongation in fission yeast.
Volume:	9
Issue:	12
Pages:	e1004029

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Protein Domain

IPR007133 | RNA_pol_II-assoc_Paf1

Type:

Family

Description:

In budding yeasts, Paf1 is part of the Paf1 complex, an RNA polymerase II-associated protein complex containing Paf1, Cdc73, Ctr9, Rtf1 and Leo1 []. Paf1 complex is involved in histone modifications, transcription elongation and other gene expression processes that include transcript site selection []. This entry also includes Paf1 homologues from animals and plants. Human Paf1, also known as PD2 (pancreatic differentiation 2), is associated with tumorigenesis []. Human Paf1 complex (Paf1C) consists of Paf1, Cdc73, Ctr9, Rtf1, Leo1 and Wdr61 (Ski8). As in yeast, the human Paf1C has a central role in co-transcriptional histone modifications []. Human Paf1 complex has a crucial role in the antiviral response []. Arabidopsis Paf1C related proteins such as VIP4 (Leo1), VIP5 (Rtf1), ELF7 (Paf1), ELF8 (Ctr9) and ATXR7 (Set1) are required for the induction of seed dormancy. They control both germination and flowering time [].

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Protein Domain

IPR031101 | Ctr9

Type:

Family

Description:

This entry includes budding yeast RNA polymerase-associated protein Ctr9 and its homologues from other yeasts, animals and plants. The homologue in fission yeast is known as tetratricopeptide repeat protein 1 (Tpr1) [].Budding yeast Ctr9 is part of the Paf1 complex, an RNA polymerase II-associated protein complex containing Paf1, Cdc73, Ctr9, Rtf1 and Leo1 []. Paf1 complex is involved in histone modifications, transcription elongation and other gene expression processes that include transcript site selection []. Human Paf1 complex (Paf1C) consists of Paf1, Cdc73, Ctr9, Rtf1, Leo1 and Wdr61 (Ski8). As in yeast, the human Paf1C has a central role in co-transcriptional histone modifications [].Arabidopsis Paf1C related proteins such as VIP4 (Leo1), VIP5 (Rtf1), ELF7 (Paf1), ELF8 (Ctr9) and ATXR7 (Set1) are required for the induction of seed dormancy. They control both germination and flowering time [].

•

Publication

1913663 | -

First Author:	Isom H
Year:	1991
Journal:	Cancer Res
Title:	Workshop report from the Division of Research Grants, National Institutes of Health. The role of chromosome rearrangements, deletions, and point mutations in cancer--a Pathology B Study Section workshop.
Volume:	51
Issue:	19
Pages:	5440-4

•

Publication

12242279 | -

First Author:	Krogan NJ
Year:	2002
Journal:	Mol Cell Biol
Title:	RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach.
Volume:	22
Issue:	20
Pages:	6979-92

•

Publication

20363855 | -

First Author:	Park S
Year:	2010
Journal:	Plant Physiol
Title:	PLANT HOMOLOGOUS TO PARAFIBROMIN is a component of the PAF1 complex and assists in regulating expression of genes within H3K27ME3-enriched chromatin.
Volume:	153
Issue:	2
Pages:	821-31

•

Publication

20463090 | -

First Author:	Yu X
Year:	2010
Journal:	Plant Physiol
Title:	The Arabidopsis Paf1c complex component CDC73 participates in the modification of FLOWERING LOCUS C chromatin.
Volume:	153
Issue:	3
Pages:	1074-84

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Protein Domain

IPR007852 | Cdc73/Parafibromin

Type:

Family

Description:

This entry includes Cdc73 from budding yeasts and its animal homologue, parafibromin. They are part of the Paf1 complex involved in histone modifications, transcription elongation and other gene expression processes that include transcript site selection [].In budding yeasts, Paf1 is an RNA polymerase II-associated protein complex containing Paf1, Cdc73, Ctr9, Rtf1 and Leo1. It is required for full expression of a subset of yeast genes, particularly those responsive to signals from the Pkc1/MAP kinase cascade. The complex appears to play an essential role in RNA elongation []. Human parafibromin is a tumour suppressor that may facilitate association of 3' mRNA processing factors with actively-transcribed chromatin. It is a component of the human Paf1 complex (Paf1C), which consists of Paf1, Cdc73, Ctr9, Rtf1, Leo1 and Wdr61 (Ski8). As in yeast, the human Paf1C has a central role in co-transcriptional histone modifications []. The Arabidopsis Cdc73 (also known as PLANT HOMOLOGOUS TO PARAFIBROMIN ,PHP) assists in regulating expression of genes within H3K27ME3-enriched chromatin []and participates in the modification of FLOWERING LOCUS C (FLC) chromatin [].

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Publication

17622165 | -

First Author:	Smith JC
Year:	2007
Journal:	J Proteome Res
Title:	A differential phosphoproteomic analysis of retinoic acid-treated P19 cells.
Volume:	6
Issue:	8
Pages:	3174-86

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Protein

Q62018

Organism:	Mus musculus/domesticus
Length:	1173
Fragment?:	false

•

Protein

Q05DK2

Organism:	Mus musculus/domesticus
Length:	939
Fragment?:	true

•

Protein

Q05CJ7

Organism:	Mus musculus/domesticus
Length:	936
Fragment?:	true

•

Protein

Q8JZM7

Organism:	Mus musculus/domesticus
Length:	531
Fragment?:	false

•

Publication

17242355 | -

First Author:	Villén J
Year:	2007
Journal:	Proc Natl Acad Sci U S A
Title:	Large-scale phosphorylation analysis of mouse liver.
Volume:	104
Issue:	5
Pages:	1488-93

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

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Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

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Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

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