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Search results 101 to 162 out of 162 for Lsm3

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0.039s
Type Details Score
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
UniProt Feature
Begin: 2
Description: U6 snRNA-associated Sm-like protein LSm3
Type: chain
End: 102
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: This entry represents Sm-like protein Lsm3. It can be found in the nuclear Lsm2-8 complex or in the cytoplasmic Lsm1-7 complex. The Lsm2-8 complex associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 snRNP, U4/U6.U5 snRNP, and free U6 snRNP). It binds and stabilizes the 3'-terminal poly(U) tract of U6 snRNA and facilitates the assembly of U4-U6 di-snRNP and U4-U6-U5 tri-snRNP [, , ]. The Lsm1-7 complex associates with deadenylated mRNA and promotes decapping in the 5'-3' mRNA decay pathway [, ]. The Sm and the Lsm proteins, characterised by the Sm-domain, have RNA-related functions. The Sm heptamer ring associates with four (U1, U2, U4, U5) snRNPs, while Lsm2-8 heptamer is part of the U6 snRNP. Another Lsm heptameric complex, Lsm1-7, which differs from Lsm2-8 by one Lsm protein, functions in mRNA decapping, a crucial step in the mRNA degradation pathway [].
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: frog, African clawed
Gene
Type: gene
Organism: frog, African clawed
Allele    
Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated; wild type
Allele  
Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap CSH055, BayGenomics
Allele Type: Gene trapped
Allele
Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated; targeted mutation 1, Velocigene
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele  
Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap OST43193, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap OST53455, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap OST60601, Lexicon Genetics
Allele Type: Gene trapped
Allele  
Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap AP0652, Wellcome Trust Sanger Institute
Allele Type: Gene trapped
Allele  
Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap Ayu21-W280, Institute of Molecular Embryology and Genetics
Allele Type: Gene trapped
Allele
Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated; targeted mutation 1, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
Allele  
Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated; gene trap IST14667G6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele
Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH
Allele Type: Targeted
Attribute String: Conditional ready, Null/knockout, Reporter
Allele
Name: LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated; endonuclease-mediated mutation 1, Xuetao Cao
Allele Type: Endonuclease-mediated
Attribute String: Modified isoform(s)
Genotype
Symbol: Lsm3/Lsm3
Background: involves: C57BL/6J
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89